Nr2f2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nr2f2
Entrez Gene ID	113984
Full Name	nuclear receptor subfamily 2, group F, member 2
Synonyms	Tfcoup2
General protein information	Preferred Names nuclear receptor subfamily 2, group F, member 2 Names COUP transcription factor 2 ARP-1 COUP transcription factor II COUP-TF II COUP-TF2 COUPb apolipoprotein A-I regulatory protein 1 apolipoprotein AI regulatory protein 1 ovalbumin upstream promoter beta nuclear receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q31
Summary	transcriptional activator or repressor; involved in determining the metabolic phenotype of hepatic cells [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_080778.2	NP_542956.1	COUP transcription factor 2
XM_006229366.3	XP_006229428.1	COUP transcription factor 2 isoform X1
XM_017588643.1	XP_017444132.1	COUP transcription factor 2 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Nr2f2	NP_033827.2
Drosophila melanogaster (fruit fly)	svp	NP_524325.1
Homo sapiens (human)	NR2F2	NP_066285.1
	NR2F2	XP_001099957.1
Pan troglodytes (chimpanzee)	NR2F2	XP_003952785.1
Canis lupus familiaris (dog)	NR2F2	XP_005618373.1
Bos taurus (cattle)	NR2F2	NP_776827.1
Rattus norvegicus (Norway rat)	Nr2f2	NP_542956.1
Gallus gallus (chicken)	NR2F2	NP_989752.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002544	XP_312394.4
Xenopus tropicalis (tropical clawed frog)	nr2f2	NP_001107703.1
Danio rerio (zebrafish)	nr2f2	NP_571258.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension.
Kumarasamy S, Waghulde H, Gopalakrishnan K, Mell B, Morgan E, Joe B
Nature communications66252(2015 Feb)

The expression of Apoc3 mRNA is regulated by HNF4? and COUP-TFII, but not acute retinoid treatments, in primary rat hepatocytes and hepatoma cells.
Howell M, Li R, Zhang R, Li Y, Chen W, Chen G
Molecular and cellular biochemistry387(1-2)241-50(2014 Feb)

Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells.
Kim BJ, Scott DA
PloS one9(1)e87518(2014)

Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.
Tornari C, Towers ER, Gale JE, Dawson SJ
PloS one9(11)e112247(2014)

Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2.
Li Y, Xia Y, Wang Y, Mao L, Gao Y, He Q, Huang M, Chen S, Hu B
Molecular neurobiology47(3)967-75(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Nr2f2 mutation in the hinge region attenuates salt-sensitive hypertension
Title: Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension.

Apoc3 expression is regulated by HNF4a and COUP-TFII but not by retinoic acid in rat hepatocytes.
Title: The expression of Apoc3 mRNA is regulated by HNF4? and COUP-TFII, but not acute retinoid treatments, in primary rat hepatocytes and hepatoma cells.

These data demonstrate that Nr2f2 is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.
Title: Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.

oxygen-glucose deprivation could induce the expressions of VEGF, Ang-1, and Ang-2, with the expression of Shh signaling components increased.
Title: Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2.

Upregulation of COUP-II gene expression in the PPF may contribute to the diaphragmatic defect in the nitrofen congenital diaphragmatic hernia rat model by inhibiting the RSP.
Title: COUP-TFII gene expression is upregulated in embryonic pleuroperitoneal folds in the nitrofen-induced congenital diaphragmatic hernia rat model.

The following Nr2f2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nr2f2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa22897	XM_006229366.3 Latest version!	Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa56291	XM_017588643.1 Latest version!	Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa00175	NM_080778.2 Latest version!	Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nr2f2 ( XM_006229366.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229428.1 Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22897
Clone ID Related Accession (Same CDS sequence)	XM_006229366.3
Accession Version	XM_006229366.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	COUP transcription factor 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229366.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGCGG TTTGGGACCT TGAACAAGGC AAATATGGTT TTGCTGTACA GAGGGGCAGG 
ATGCCGCCCA CCCAGCCTAC TCACGGGCAG TTTGCACTGA CCAACGGGGA CCCCCTCAAC 
TGCCACTCGT ACCTGTCCGG ATATATTTCC CTGCTGCTGC GCGCGGAGCC CTACCCCACG 
TCGCGCTTCG GCAGTCAGTG CATGCAGCCT AACAACATCA TGGGCATCGA GAACATTTGC 
GAACTGGCCG CACGGATGCT CTTCAGCGCC GTTGAGTGGG CCCGGAACAT CCCCTTCTTC 
CCTGACCTGC AGATCACGGA CCAGGTGGCC CTCCTTCGCC TCACCTGGAG CGAGCTGTTC 
GTGTTGAATG CAGCACAGTG CTCCATGCCC CTCCATGTTG CCCCGCTCCT TGCCGCTGCT 
GGCCTGCACG CTTCACCCAT GTCAGCCGAC CGGGTGGTCG CCTTTATGGA CCACATACGG 
ATCTTCCAAG AGCAAGTGGA GAAGCTCAAG GCACTGCACG TCGACTCCGC CGAGTACAGC 
TGCCTCAAGG CCATAGTCCT GTTCACCTCA GATGCCTGTG GTCTGTCTGA TGTAGCCCAC 
GTGGAAAGTT TGCAGGAAAA GTCCCAGTGT GCTTTGGAAG AGTACGTTAG GAGCCAGTAC 
CCCAACCAGC CAACACGGTT CGGAAAGCTT TTGCTTCGTC TCCCTTCCCT CCGCACGGTC 
TCCTCCTCAG TCATAGAGCA ATTGTTTTTC GTCCGTTTGG TAGGTAAAAC CCCCATCGAA 
ACCCTCATCC GGGATATGTT ACTGTCCGGC AGCAGTTTTA ACTGGCCATA CATGGCAATT 
CAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229428.1
CDS	5475..6320
Translation	MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ

Target ORF information:

RefSeq Version	XM_006229366.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229366.3

ORF Insert Sequence:

ATGCAAGCGG TTTGGGACCT TGAACAAGGC AAATATGGTT TTGCTGTACA GAGGGGCAGG 
ATGCCGCCCA CCCAGCCTAC TCACGGGCAG TTTGCACTGA CCAACGGGGA CCCCCTCAAC 
TGCCACTCGT ACCTGTCCGG ATATATTTCC CTGCTGCTGC GCGCGGAGCC CTACCCCACG 
TCGCGCTTCG GCAGTCAGTG CATGCAGCCT AACAACATCA TGGGCATCGA GAACATTTGC 
GAACTGGCCG CACGGATGCT CTTCAGCGCC GTTGAGTGGG CCCGGAACAT CCCCTTCTTC 
CCTGACCTGC AGATCACGGA CCAGGTGGCC CTCCTTCGCC TCACCTGGAG CGAGCTGTTC 
GTGTTGAATG CAGCACAGTG CTCCATGCCC CTCCATGTTG CCCCGCTCCT TGCCGCTGCT 
GGCCTGCACG CTTCACCCAT GTCAGCCGAC CGGGTGGTCG CCTTTATGGA CCACATACGG 
ATCTTCCAAG AGCAAGTGGA GAAGCTCAAG GCACTGCACG TCGACTCCGC CGAGTACAGC 
TGCCTCAAGG CCATAGTCCT GTTCACCTCA GATGCCTGTG GTCTGTCTGA TGTAGCCCAC 
GTGGAAAGTT TGCAGGAAAA GTCCCAGTGT GCTTTGGAAG AGTACGTTAG GAGCCAGTAC 
CCCAACCAGC CAACACGGTT CGGAAAGCTT TTGCTTCGTC TCCCTTCCCT CCGCACGGTC 
TCCTCCTCAG TCATAGAGCA ATTGTTTTTC GTCCGTTTGG TAGGTAAAAC CCCCATCGAA 
ACCCTCATCC GGGATATGTT ACTGTCCGGC AGCAGTTTTA ACTGGCCATA CATGGCAATT 
CAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr2f2 ( XM_017588643.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444132.1 Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa56291
Clone ID Related Accession (Same CDS sequence)	XM_017588643.1
Accession Version	XM_017588643.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	COUP transcription factor 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGCCCA CCCAGCCTAC TCACGGGCAG TTTGCACTGA CCAACGGGGA CCCCCTCAAC 
TGCCACTCGT ACCTGTCCGG ATATATTTCC CTGCTGCTGC GCGCGGAGCC CTACCCCACG 
TCGCGCTTCG GCAGTCAGTG CATGCAGCCT AACAACATCA TGGGCATCGA GAACATTTGC 
GAACTGGCCG CACGGATGCT CTTCAGCGCC GTTGAGTGGG CCCGGAACAT CCCCTTCTTC 
CCTGACCTGC AGATCACGGA CCAGGTGGCC CTCCTTCGCC TCACCTGGAG CGAGCTGTTC 
GTGTTGAATG CAGCACAGTG CTCCATGCCC CTCCATGTTG CCCCGCTCCT TGCCGCTGCT 
GGCCTGCACG CTTCACCCAT GTCAGCCGAC CGGGTGGTCG CCTTTATGGA CCACATACGG 
ATCTTCCAAG AGCAAGTGGA GAAGCTCAAG GCACTGCACG TCGACTCCGC CGAGTACAGC 
TGCCTCAAGG CCATAGTCCT GTTCACCTCA GATGCCTGTG GTCTGTCTGA TGTAGCCCAC 
GTGGAAAGTT TGCAGGAAAA GTCCCAGTGT GCTTTGGAAG AGTACGTTAG GAGCCAGTAC 
CCCAACCAGC CAACACGGTT CGGAAAGCTT TTGCTTCGTC TCCCTTCCCT CCGCACGGTC 
TCCTCCTCAG TCATAGAGCA ATTGTTTTTC GTCCGTTTGG TAGGTAAAAC CCCCATCGAA 
ACCCTCATCC GGGATATGTT ACTGTCCGGC AGCAGTTTTA ACTGGCCATA CATGGCAATT 
CAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444132.1
CDS	96..881
Translation	MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ

Target ORF information:

RefSeq Version	XM_017588643.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588643.1

ORF Insert Sequence:

ATGCCGCCCA CCCAGCCTAC TCACGGGCAG TTTGCACTGA CCAACGGGGA CCCCCTCAAC 
TGCCACTCGT ACCTGTCCGG ATATATTTCC CTGCTGCTGC GCGCGGAGCC CTACCCCACG 
TCGCGCTTCG GCAGTCAGTG CATGCAGCCT AACAACATCA TGGGCATCGA GAACATTTGC 
GAACTGGCCG CACGGATGCT CTTCAGCGCC GTTGAGTGGG CCCGGAACAT CCCCTTCTTC 
CCTGACCTGC AGATCACGGA CCAGGTGGCC CTCCTTCGCC TCACCTGGAG CGAGCTGTTC 
GTGTTGAATG CAGCACAGTG CTCCATGCCC CTCCATGTTG CCCCGCTCCT TGCCGCTGCT 
GGCCTGCACG CTTCACCCAT GTCAGCCGAC CGGGTGGTCG CCTTTATGGA CCACATACGG 
ATCTTCCAAG AGCAAGTGGA GAAGCTCAAG GCACTGCACG TCGACTCCGC CGAGTACAGC 
TGCCTCAAGG CCATAGTCCT GTTCACCTCA GATGCCTGTG GTCTGTCTGA TGTAGCCCAC 
GTGGAAAGTT TGCAGGAAAA GTCCCAGTGT GCTTTGGAAG AGTACGTTAG GAGCCAGTAC 
CCCAACCAGC CAACACGGTT CGGAAAGCTT TTGCTTCGTC TCCCTTCCCT CCGCACGGTC 
TCCTCCTCAG TCATAGAGCA ATTGTTTTTC GTCCGTTTGG TAGGTAAAAC CCCCATCGAA 
ACCCTCATCC GGGATATGTT ACTGTCCGGC AGCAGTTTTA ACTGGCCATA CATGGCAATT 
CAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr2f2 ( NM_080778.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_542956.1 Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), mRNA.

Price & Availability↑

CloneID	ORa00175
Clone ID Related Accession (Same CDS sequence)	NM_080778.2
Accession Version	NM_080778.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	COUP transcription factor 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF003944.1. On Aug 31, 2012 this sequence version replaced NM_080778.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF003944.1, EV770714.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906351, SAMN01906357 [ECO:0000348] ##Evidence-Data-END##

ATGGCAATGG TAGTCAGCAC GTGGCGCGAC CCCCAGGACG AGGTGCCCGG CTCTCAGGGC 
AGCCAGGCCT CGCAGGCGCC GCCCGTGCCG GGCCCGCCGC CTGGCGCCCC GCACACGCCA 
CAGACGCCGG GCCAAGGGGG CCCGGCCAGC ACGCCGGCCC AGACAGCGGC TGGCAGCCAG 
GGCGGCCCTG GCGGCCCAGG CAGCGACAAA CAGCAGCAGC AGCAGCACAT CGAGTGCGTG 
GTGTGCGGGG ACAAGTCGAG CGGCAAGCAC TACGGCCAGT TCACGTGCGA GGGCTGCAAG 
AGCTTCTTCA AGCGCAGCGT GCGGAGGAAC CTGAGCTACA CGTGCCGCGC CAACCGGAAC 
TGTCCCATCG ACCAGCACCA CCGCAACCAG TGCCAGTACT GCCGCCTCAA AAAGTGCCTC 
AAAGTGGGCA TGAGACGGGA AGCTGTACAG AGGGGCAGGA TGCCGCCCAC CCAGCCTACT 
CACGGGCAGT TTGCACTGAC CAACGGGGAC CCCCTCAACT GCCACTCGTA CCTGTCCGGA 
TATATTTCCC TGCTGCTGCG CGCGGAGCCC TACCCCACGT CGCGCTTCGG CAGTCAGTGC 
ATGCAGCCTA ACAACATCAT GGGCATCGAG AACATTTGCG AACTGGCCGC ACGGATGCTC 
TTCAGCGCCG TTGAGTGGGC CCGGAACATC CCCTTCTTCC CTGACCTGCA GATCACGGAC 
CAGGTGGCCC TCCTTCGCCT CACCTGGAGC GAGCTGTTCG TGTTGAATGC AGCACAGTGC 
TCCATGCCCC TCCATGTTGC CCCGCTCCTT GCCGCTGCTG GCCTGCACGC TTCACCCATG 
TCAGCCGACC GGGTGGTCGC CTTTATGGAC CACATACGGA TCTTCCAAGA GCAAGTGGAG 
AAGCTCAAGG CACTGCACGT CGACTCCGCC GAGTACAGCT GCCTCAAGGC CATAGTCCTG 
TTCACCTCAG ATGCCTGTGG TCTGTCTGAT GTAGCCCACG TGGAAAGTTT GCAGGAAAAG 
TCCCAGTGTG CTTTGGAAGA GTACGTTAGG AGCCAGTACC CCAACCAGCC AACACGGTTC 
GGAAAGCTTT TGCTTCGTCT CCCTTCCCTC CGCACGGTCT CCTCCTCAGT CATAGAGCAA 
TTGTTTTTCG TCCGTTTGGT AGGTAAAACC CCCATCGAAA CCCTCATCCG GGATATGTTA 
CTGTCCGGCA GCAGTTTTAA CTGGCCATAC ATGGCAATTC AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542956.1
CDS	185..1429
Translation	MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGSQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ

Target ORF information:

RefSeq Version	NM_080778.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080778.2

ORF Insert Sequence:

ATGGCAATGG TAGTCAGCAC GTGGCGCGAC CCCCAGGACG AGGTGCCCGG CTCTCAGGGC 
AGCCAGGCCT CGCAGGCGCC GCCCGTGCCG GGCCCGCCGC CTGGCGCCCC GCACACGCCA 
CAGACGCCGG GCCAAGGGGG CCCGGCCAGC ACGCCGGCCC AGACAGCGGC TGGCAGCCAG 
GGCGGCCCTG GCGGCCCAGG CAGCGACAAA CAGCAGCAGC AGCAGCACAT CGAGTGCGTG 
GTGTGCGGGG ACAAGTCGAG CGGCAAGCAC TACGGCCAGT TCACGTGCGA GGGCTGCAAG 
AGCTTCTTCA AGCGCAGCGT GCGGAGGAAC CTGAGCTACA CGTGCCGCGC CAACCGGAAC 
TGTCCCATCG ACCAGCACCA CCGCAACCAG TGCCAGTACT GCCGCCTCAA AAAGTGCCTC 
AAAGTGGGCA TGAGACGGGA AGCTGTACAG AGGGGCAGGA TGCCGCCCAC CCAGCCTACT 
CACGGGCAGT TTGCACTGAC CAACGGGGAC CCCCTCAACT GCCACTCGTA CCTGTCCGGA 
TATATTTCCC TGCTGCTGCG CGCGGAGCCC TACCCCACGT CGCGCTTCGG CAGTCAGTGC 
ATGCAGCCTA ACAACATCAT GGGCATCGAG AACATTTGCG AACTGGCCGC ACGGATGCTC 
TTCAGCGCCG TTGAGTGGGC CCGGAACATC CCCTTCTTCC CTGACCTGCA GATCACGGAC 
CAGGTGGCCC TCCTTCGCCT CACCTGGAGC GAGCTGTTCG TGTTGAATGC AGCACAGTGC 
TCCATGCCCC TCCATGTTGC CCCGCTCCTT GCCGCTGCTG GCCTGCACGC TTCACCCATG 
TCAGCCGACC GGGTGGTCGC CTTTATGGAC CACATACGGA TCTTCCAAGA GCAAGTGGAG 
AAGCTCAAGG CACTGCACGT CGACTCCGCC GAGTACAGCT GCCTCAAGGC CATAGTCCTG 
TTCACCTCAG ATGCCTGTGG TCTGTCTGAT GTAGCCCACG TGGAAAGTTT GCAGGAAAAG 
TCCCAGTGTG CTTTGGAAGA GTACGTTAGG AGCCAGTACC CCAACCAGCC AACACGGTTC 
GGAAAGCTTT TGCTTCGTCT CCCTTCCCTC CGCACGGTCT CCTCCTCAGT CATAGAGCAA 
TTGTTTTTCG TCCGTTTGGT AGGTAAAACC CCCATCGAAA CCCTCATCCG GGATATGTTA 
CTGTCCGGCA GCAGTTTTAA CTGGCCATAC ATGGCAATTC AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension.
Nature communications66252(2015 Feb)
Kumarasamy S,Waghulde H,Gopalakrishnan K,Mell B,Morgan E,Joe B

The expression of Apoc3 mRNA is regulated by HNF4? and COUP-TFII, but not acute retinoid treatments, in primary rat hepatocytes and hepatoma cells.
Molecular and cellular biochemistry387(1-2)241-50(2014 Feb)
Howell M,Li R,Zhang R,Li Y,Chen W,Chen G

Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells.
PloS one9(1)e87518(2014)
Kim BJ,Scott DA

Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.
PloS one9(11)e112247(2014)
Tornari C,Towers ER,Gale JE,Dawson SJ

Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2.
Molecular neurobiology47(3)967-75(2013 Jun)
Li Y,Xia Y,Wang Y,Mao L,Gao Y,He Q,Huang M,Chen S,Hu B

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Nr2f2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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