Magi2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Magi2
Entrez Gene ID	113970
Full Name	membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms	Acvrinp1,Acvrip1,S-SCAM
General protein information	Preferred Names membrane associated guanylate kinase, WW and PDZ domain containing 2 Names membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 AIP-1 MAGI-2 activin receptor interacting protein 1 atrophin-1-interacting protein 1 membrane-associated guanylate kinase inverted 2 synaptic-scaffolding molecule
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_053621.1	NP_446073.1	membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	MAGI2	NP_001186469.1
Danio rerio (zebrafish)	magi2	NP_001116083.1
Homo sapiens (human)	MAGI2	NP_036433.2
Mus musculus (house mouse)	Magi2	NP_001164217.1
Caenorhabditis elegans (roundworm)	magi-1	NP_001255577.1
Pan troglodytes (chimpanzee)	MAGI2	XP_519172.3
Rattus norvegicus (Norway rat)	Magi2	NP_446073.1
Canis lupus familiaris (dog)	MAGI2	XP_005631075.1
Bos taurus (cattle)	MAGI2	XP_002686815.1

Gene Ontology
Bibliography

Related articles in PubMed

Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
Bender J, Engeholm M, Ederer MS, Breu J, M?ller TC, Michalakis S, Rasko T, Wanker EE, Biel M, Martinez KL, Wurst W, Deussing JM
PloS one10(9)e0136768(2015)

The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development.
Woo J, Kwon SK, Nam J, Choi S, Takahashi H, Krueger D, Park J, Lee Y, Bae JY, Lee D, Ko J, Kim H, Kim MH, Bae YC, Chang S, Craig AM, Kim E
The Journal of cell biology201(6)929-44(2013 Jun)

Wistar rats subjected to chronic restraint stress display increased hippocampal spine density paralleled by increased expression levels of synaptic scaffolding proteins.
Orlowski D, Elfving B, M?ller HK, Wegener G, Bjarkam CR
Stress (Amsterdam, Netherlands)15(5)514-23(2012 Sep)

S-SCAM/MAGI-2 is an essential synaptic scaffolding molecule for the GluA2-containing maintenance pool of AMPA receptors.
Danielson E, Zhang N, Metallo J, Kaleka K, Shin SM, Gerges N, Lee SH
The Journal of neuroscience : the official journal of the Society for Neuroscience32(20)6967-80(2012 May)

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.
Babayeva S, Zilber Y, Torban E
American journal of physiology. Renal physiology300(2)F549-60(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chronic restraint stress influences hippocampal neuroplasticity by modulation of dendrite branching pattern and spine density paralleled by increased expression levels of synaptic scaffolding proteins.
Title: Wistar rats subjected to chronic restraint stress display increased hippocampal spine density paralleled by increased expression levels of synaptic scaffolding proteins.

these results suggest that S-SCAM is an essential AMPAR scaffolding molecule for the GluA2-containing pool of AMPARs, which are involved in the constitutive pathway of maintaining synaptic strength.
Title: S-SCAM/MAGI-2 is an essential synaptic scaffolding molecule for the GluA2-containing maintenance pool of AMPA receptors.

We identified Axin as a novel binding partner of S-SCAM. Axin was co-immunoprecipitated with S-SCAM from rat brain
Title: Synaptic scaffolding molecule interacts with axin.

The following Magi2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Magi2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10108	NM_053621.1 Latest version!	Rattus norvegicus membrane associated guanylate kinase, WW and PDZ domain containing 2 (Magi2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Magi2 ( NM_053621.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446073.1 Rattus norvegicus membrane associated guanylate kinase, WW and PDZ domain containing 2 (Magi2), mRNA.

Price & Availability↑

CloneID	ORa10108
Clone ID Related Accession (Same CDS sequence)	NM_053621.1
Accession Version	NM_053621.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-06
Organism	Rattus norvegicus(Norway rat)
Product	membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF034863.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF034863.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCCAAAA GCTTGAAAAA GAAAAGCCAC TGGACTAGCA AAGTCCACGA GAGTGTCATT 
GGCAGAAACC CGGAGGGCCA GCTGGGCTTT GAACTGAAGG GGGGCGCCGA AAACGGACAG 
TTCCCCTACC TGGGGGAGGT GAAGCCGGGC AAGGTGGCCT ATGAAAGCGG CAGCAAGTTG 
GTGTCCGAGG AGCTGCTGCT GGAGGTGAAC GAGACCCCCG TGGCGGGGCT CACCATCAGG 
GATGTTCTGG CCGTGATCAA ACACTGCAAG GACCCCCTCC GGCTCAAGTG TGTCAAGCAA 
GGAGGAATTG TTGATAAGGA TCTTCGTCAC TACCTCAACT TAAGATTTCA GAAGGGTTCT 
GTTGACCACG AACTACAGCA AATCATCCGT GACAACCTCT ACCTCCGCAC AGTGCCATGC 
ACCACAAGGC CACATAAGGA GGGTGAGGTC CCTGGAGTGG ACTACATTTT CATAACCGTT 
GAGGACTTTA TGGAATTGGA GAAAAGCGGT GCTCTCCTAG AAAGTGGGAC CTATGAAGAC 
AACTATTACG GCACTCCAAA GCCTCCAGCT GAACCAGCAC CATTATTATT AAATGTAACA 
GATCAGATAC TCCCGGGAGC TACTCCAAGT GCTGAGGGGA AGCGGAAAAG AAATAAGTCT 
GTGACCAACA TGGAGAAAGC AAGTATAGAG CCACCGGAGG AAGAGGAGGA AGAAAGGCCT 
GTGGTCAACG GAAATGGCGT CGTCATAACA CCAGAATCCA GTGAACATGA AGACAAAAGT 
GCAGGTGCCT CAGGGGAGAC CCCCTCCCAG CCTTACCCTG CACCAGTGTA CAGTCAGCCT 
GAAGAGCTCA AGGACCAGAT GGATGATACA AAGTCAACAA AGCCCGAGGA GAATGAGGAC 
TCCGACCCAT TGCCTGATAA CTGGGAAATG GCCTACACAG AGAAGGGTGA AGTCTACTTC 
ATTGACCATA ACACAAAGAC AACATCATGG CTGGATCCAC GACTTGCCAA AAAGGCTAAG 
CCTGCAGAGG AGTGCAAGGA AAATGAGCTT CCATATGGCT GGGAAAAAAT CGATGATCCT 
ATATATGGCA CTTACTATGT CGACCACATA AATAGAAGAA CACAGTTTGA AAACCCTGTC 
CTGGAAGCAA AAAGGAAGCT ACAGCAACAT AACATGCCCC ACACAGAACT TGGAACAAAG 
CCCCTGCAGG CCCCAGGTTT CCGAGAAAAG CCACTCTTCA CCCGGGATGC ATCCCAGTTG 
AAGGGAACAT TCCTCAGCAC CACCCTCAAA AAGAGCAACA TGGGCTTTGG GTTTACGATC 
ATCGGTGGAG ATGAGCCGGA CGAGTTTCTA CAGGTGAAGA GTGTGATCCC GGATGGGCCC 
GCCGCACAGG ATGGGAAAAT GGAGACAGGT GATGTCATTG TCTATATTAA TGAAGTTTGT 
GTCCTTGGAC ACACTCATGC AGATGTTGTC AAACTTTTCC AGTCTGTTCC TATTGGTCAG 
AGCGTCAACC TGGTGTTGTG TCGTGGCTAC CCTTTGCCCT TTGATCCTGA AGACCCTGCC 
AACAGCATGG TGCCACCCCT TGCAATAATG GAGAGGCCAC CTCCGGTGAT GGTCAATGGA 
AGACATAACT ATGAAACATA TTTGGAATAC ATTTCTCGGA CCTCACAGTC GGTCCCAGAT 
ATTACAGACC GGCCACCTCA TTCTTTGCAC TCCATGCCAG CTGATGGCCA ACTAGATGGC 
ACATATCCAC CACCCGTCCA CGATGACAAT GTGTCTGTGG CTTCATCTGG AGCCACTCAA 
GCTGAACTTA TGACCTTAAC CATTGTGAAA GGTGCCAAGG GATTTGGCTT TACTATTGCC 
GACAGTCCCA CGGGACAGCG GGTGAAACAA ATACTTGACA TTCAGGGATG CCCCGGGCTG 
TGTGAAGGAG ACCTCATTGT TGAGATCAAT CAACAGAATG TACAGAACCT GAGCCATACA 
GAAGTGGTTG ATATACTTAA GGACTGCCCC GTCGGAAGCG AGACTTCTCT AATCATCCAT 
CGAGGAGGTT TCTTTTCTCC ATGGAAAACT CCAAAGCCTA TGGTGGACCG GTGGGAGAAC 
CAAGGCAGCC CTCAAACAAG TTTATCTGCT CCGGCCGTCC CACAGAGCCT GCCCTTCCCA 
CCTGCCCTTC ATAGGAGCTC CTTTCCTGAC TCAACAGAGG CCTTTGACCC ACGGAAGCCT 
GACCCGTATG AGCTCTACGA GAAATCGAGA GCCATTTATG AAAGTAGGCA ACAAGTGCCA 
CCCAGGACCA GTTTTCGAAT GGATTCCTCT GGTCCAGATT ATAAGGAATT GGATGTTCAC 
CTTCGGAGGA TGGAGTCTGG ATTTGGCTTC AGAATCCTTG GGGGAGACGA GCCCGGACAG 
CCTATTTTGA TCGGAGCTGT CATTGCGATG GGCTCAGCTG ACAGAGACGG CCGTCTGCAC 
CCAGGAGACG AGCTTGTCTA CGTGGATGGG ATCCCGGTGG CTGGCAAGAC CCACCGGTAT 
GTCATCGACC TCATGCACCA TGCGGCCCGC AACGGGCAGG TTAACCTCAC TGTGAGAAGA 
AAGGTGCTAT GTGGAGGGGA GCCCTGCCCA GAGAATGGGA GGAGTCCAGG CTCTGTATCA 
ACACACCACA GCTCTCCCCG CAGTGACTAT GCCACCTACG CCAACAGCAA CCACGCGGCC 
CCCAGTAACA ATGCCTCACC CCCTGAAGGC TTTGCCTCGC ACAGCCTGCA GACCAGTGAC 
GTCATCATTC ACCGAAAGGA AAACGAAGGC TTCGGCTTCG TCATCATCAG CTCCCTGAAC 
AGGCCTGAGT CTGGAGCCAC CATAACCGTG CCCCATAAAA TCGGACGAAT CATCGATGGG 
AGCCCTGCAG ATCGCTGCGC AAAACTCAAA GTGGGCGACC GGATCTTAGC AGTCAACGGC 
CAGTCTATCA TCAACATGCC TCACGCTGAC ATCGTGAAGC TCATCAAGGA TGCGGGTCTC 
AGCGTCACCC TCCGCATCAT TCCTCAGGAG GAGCTCAACA ACCCAACATC AGCACCCAGT 
TCAGAGAAGC AGAGCCCCAT GGCCCAGCAG CACAGCCCTC TGGCCCAGCA GCACAGCCCT 
CTGGCCCAGC CGAGCCCAGC CACCCCCAAC AGCCCAGTTG CACAGCCAGC TCCTCCTCAA 
CCTCTCCAGC TGCAAGGACA TGAAAATAGT TACAGGTCAG AAGTTAAAGC AAGGCAAGAT 
GTGAAGCCAG ACATCCGGCA GCCGCCCTTC ACAGACTACA GGCAGCCGCC ACTGGACTAC 
AGGCAACCCC CGGGAGGGGA CTACTCGCAG CCCTCACCCT TGGACTACAG GCAGCACTCC 
CCAGACACCA GGCAGTACCC TCTGTCAGAC TACAGGCAGC CACAGGATTT CGATTATTTC 
ACTGTGGACA TGGAGAAAGG AGCCAAAGGA TTTGGATTCA GCATCCGTGG AGGAAGGGAA 
TACAAAATGG ATCTGTACGT GTTGAGATTG GCGGAGGATG GGCCAGCCAT AAGGAACGGC 
AGGATGAGGG TGGGAGATCA GATCATCGAA ATAAATGGGG AAAGCACACG AGACATGACC 
CACGCCAGAG CAATAGAACT CATCAAGTCG GGAGGAAGAA GAGTGCGGTT GCTGCTGAAA 
CGAGGCACGG GGCAGGTCCC AGAGTATGGA ATGGTGCCTT CCAGCCTCTC CATGTGCATG 
AAAAGTGACA AGCATGGGTC CCCATATTTC TACTTACTGG GCCACCCTAA AGACACGACG 
AACCCTACGC CTGGAGCGCT GCCGCTGCCG CCGCCCCAGG CCTGCCGGAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446073.1
CDS	151..3984
Translation	MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKLVSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVTNMEKASIEPPEEEEEERPVVNGNGVVITPESSEHEDKSAGASGETPSQPYPAPVYSQPEELKDQMDDTKSTKPEENEDSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPAEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPADGQLDGTYPPPVHDDNVSVASSGATQAELMTLTIVKGAKGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETSLIIHRGGFFSPWKTPKPMVDRWENQGSPQTSLSAPAVPQSLPFPPALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYANSNHAAPSNNASPPEGFASHSLQTSDVIIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNNPTSAPSSEKQSPMAQQHSPLAQQHSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYSQPSPLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTTNPTPGALPLPPPQACRK

Target ORF information:

RefSeq Version	NM_053621.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus membrane associated guanylate kinase, WW and PDZ domain containing 2 (Magi2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053621.1

ORF Insert Sequence:

ATGTCCAAAA GCTTGAAAAA GAAAAGCCAC TGGACTAGCA AAGTCCACGA GAGTGTCATT 
GGCAGAAACC CGGAGGGCCA GCTGGGCTTT GAACTGAAGG GGGGCGCCGA AAACGGACAG 
TTCCCCTACC TGGGGGAGGT GAAGCCGGGC AAGGTGGCCT ATGAAAGCGG CAGCAAGTTG 
GTGTCCGAGG AGCTGCTGCT GGAGGTGAAC GAGACCCCCG TGGCGGGGCT CACCATCAGG 
GATGTTCTGG CCGTGATCAA ACACTGCAAG GACCCCCTCC GGCTCAAGTG TGTCAAGCAA 
GGAGGAATTG TTGATAAGGA TCTTCGTCAC TACCTCAACT TAAGATTTCA GAAGGGTTCT 
GTTGACCACG AACTACAGCA AATCATCCGT GACAACCTCT ACCTCCGCAC AGTGCCATGC 
ACCACAAGGC CACATAAGGA GGGTGAGGTC CCTGGAGTGG ACTACATTTT CATAACCGTT 
GAGGACTTTA TGGAATTGGA GAAAAGCGGT GCTCTCCTAG AAAGTGGGAC CTATGAAGAC 
AACTATTACG GCACTCCAAA GCCTCCAGCT GAACCAGCAC CATTATTATT AAATGTAACA 
GATCAGATAC TCCCGGGAGC TACTCCAAGT GCTGAGGGGA AGCGGAAAAG AAATAAGTCT 
GTGACCAACA TGGAGAAAGC AAGTATAGAG CCACCGGAGG AAGAGGAGGA AGAAAGGCCT 
GTGGTCAACG GAAATGGCGT CGTCATAACA CCAGAATCCA GTGAACATGA AGACAAAAGT 
GCAGGTGCCT CAGGGGAGAC CCCCTCCCAG CCTTACCCTG CACCAGTGTA CAGTCAGCCT 
GAAGAGCTCA AGGACCAGAT GGATGATACA AAGTCAACAA AGCCCGAGGA GAATGAGGAC 
TCCGACCCAT TGCCTGATAA CTGGGAAATG GCCTACACAG AGAAGGGTGA AGTCTACTTC 
ATTGACCATA ACACAAAGAC AACATCATGG CTGGATCCAC GACTTGCCAA AAAGGCTAAG 
CCTGCAGAGG AGTGCAAGGA AAATGAGCTT CCATATGGCT GGGAAAAAAT CGATGATCCT 
ATATATGGCA CTTACTATGT CGACCACATA AATAGAAGAA CACAGTTTGA AAACCCTGTC 
CTGGAAGCAA AAAGGAAGCT ACAGCAACAT AACATGCCCC ACACAGAACT TGGAACAAAG 
CCCCTGCAGG CCCCAGGTTT CCGAGAAAAG CCACTCTTCA CCCGGGATGC ATCCCAGTTG 
AAGGGAACAT TCCTCAGCAC CACCCTCAAA AAGAGCAACA TGGGCTTTGG GTTTACGATC 
ATCGGTGGAG ATGAGCCGGA CGAGTTTCTA CAGGTGAAGA GTGTGATCCC GGATGGGCCC 
GCCGCACAGG ATGGGAAAAT GGAGACAGGT GATGTCATTG TCTATATTAA TGAAGTTTGT 
GTCCTTGGAC ACACTCATGC AGATGTTGTC AAACTTTTCC AGTCTGTTCC TATTGGTCAG 
AGCGTCAACC TGGTGTTGTG TCGTGGCTAC CCTTTGCCCT TTGATCCTGA AGACCCTGCC 
AACAGCATGG TGCCACCCCT TGCAATAATG GAGAGGCCAC CTCCGGTGAT GGTCAATGGA 
AGACATAACT ATGAAACATA TTTGGAATAC ATTTCTCGGA CCTCACAGTC GGTCCCAGAT 
ATTACAGACC GGCCACCTCA TTCTTTGCAC TCCATGCCAG CTGATGGCCA ACTAGATGGC 
ACATATCCAC CACCCGTCCA CGATGACAAT GTGTCTGTGG CTTCATCTGG AGCCACTCAA 
GCTGAACTTA TGACCTTAAC CATTGTGAAA GGTGCCAAGG GATTTGGCTT TACTATTGCC 
GACAGTCCCA CGGGACAGCG GGTGAAACAA ATACTTGACA TTCAGGGATG CCCCGGGCTG 
TGTGAAGGAG ACCTCATTGT TGAGATCAAT CAACAGAATG TACAGAACCT GAGCCATACA 
GAAGTGGTTG ATATACTTAA GGACTGCCCC GTCGGAAGCG AGACTTCTCT AATCATCCAT 
CGAGGAGGTT TCTTTTCTCC ATGGAAAACT CCAAAGCCTA TGGTGGACCG GTGGGAGAAC 
CAAGGCAGCC CTCAAACAAG TTTATCTGCT CCGGCCGTCC CACAGAGCCT GCCCTTCCCA 
CCTGCCCTTC ATAGGAGCTC CTTTCCTGAC TCAACAGAGG CCTTTGACCC ACGGAAGCCT 
GACCCGTATG AGCTCTACGA GAAATCGAGA GCCATTTATG AAAGTAGGCA ACAAGTGCCA 
CCCAGGACCA GTTTTCGAAT GGATTCCTCT GGTCCAGATT ATAAGGAATT GGATGTTCAC 
CTTCGGAGGA TGGAGTCTGG ATTTGGCTTC AGAATCCTTG GGGGAGACGA GCCCGGACAG 
CCTATTTTGA TCGGAGCTGT CATTGCGATG GGCTCAGCTG ACAGAGACGG CCGTCTGCAC 
CCAGGAGACG AGCTTGTCTA CGTGGATGGG ATCCCGGTGG CTGGCAAGAC CCACCGGTAT 
GTCATCGACC TCATGCACCA TGCGGCCCGC AACGGGCAGG TTAACCTCAC TGTGAGAAGA 
AAGGTGCTAT GTGGAGGGGA GCCCTGCCCA GAGAATGGGA GGAGTCCAGG CTCTGTATCA 
ACACACCACA GCTCTCCCCG CAGTGACTAT GCCACCTACG CCAACAGCAA CCACGCGGCC 
CCCAGTAACA ATGCCTCACC CCCTGAAGGC TTTGCCTCGC ACAGCCTGCA GACCAGTGAC 
GTCATCATTC ACCGAAAGGA AAACGAAGGC TTCGGCTTCG TCATCATCAG CTCCCTGAAC 
AGGCCTGAGT CTGGAGCCAC CATAACCGTG CCCCATAAAA TCGGACGAAT CATCGATGGG 
AGCCCTGCAG ATCGCTGCGC AAAACTCAAA GTGGGCGACC GGATCTTAGC AGTCAACGGC 
CAGTCTATCA TCAACATGCC TCACGCTGAC ATCGTGAAGC TCATCAAGGA TGCGGGTCTC 
AGCGTCACCC TCCGCATCAT TCCTCAGGAG GAGCTCAACA ACCCAACATC AGCACCCAGT 
TCAGAGAAGC AGAGCCCCAT GGCCCAGCAG CACAGCCCTC TGGCCCAGCA GCACAGCCCT 
CTGGCCCAGC CGAGCCCAGC CACCCCCAAC AGCCCAGTTG CACAGCCAGC TCCTCCTCAA 
CCTCTCCAGC TGCAAGGACA TGAAAATAGT TACAGGTCAG AAGTTAAAGC AAGGCAAGAT 
GTGAAGCCAG ACATCCGGCA GCCGCCCTTC ACAGACTACA GGCAGCCGCC ACTGGACTAC 
AGGCAACCCC CGGGAGGGGA CTACTCGCAG CCCTCACCCT TGGACTACAG GCAGCACTCC 
CCAGACACCA GGCAGTACCC TCTGTCAGAC TACAGGCAGC CACAGGATTT CGATTATTTC 
ACTGTGGACA TGGAGAAAGG AGCCAAAGGA TTTGGATTCA GCATCCGTGG AGGAAGGGAA 
TACAAAATGG ATCTGTACGT GTTGAGATTG GCGGAGGATG GGCCAGCCAT AAGGAACGGC 
AGGATGAGGG TGGGAGATCA GATCATCGAA ATAAATGGGG AAAGCACACG AGACATGACC 
CACGCCAGAG CAATAGAACT CATCAAGTCG GGAGGAAGAA GAGTGCGGTT GCTGCTGAAA 
CGAGGCACGG GGCAGGTCCC AGAGTATGGA ATGGTGCCTT CCAGCCTCTC CATGTGCATG 
AAAAGTGACA AGCATGGGTC CCCATATTTC TACTTACTGG GCCACCCTAA AGACACGACG 
AACCCTACGC CTGGAGCGCT GCCGCTGCCG CCGCCCCAGG CCTGCCGGAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
PloS one10(9)e0136768(2015)
Bender J,Engeholm M,Ederer MS,Breu J,M?ller TC,Michalakis S,Rasko T,Wanker EE,Biel M,Martinez KL,Wurst W,Deussing JM

The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development.
The Journal of cell biology201(6)929-44(2013 Jun)
Woo J,Kwon SK,Nam J,Choi S,Takahashi H,Krueger D,Park J,Lee Y,Bae JY,Lee D,Ko J,Kim H,Kim MH,Bae YC,Chang S,Craig AM,Kim E

Wistar rats subjected to chronic restraint stress display increased hippocampal spine density paralleled by increased expression levels of synaptic scaffolding proteins.
Stress (Amsterdam, Netherlands)15(5)514-23(2012 Sep)
Orlowski D,Elfving B,M?ller HK,Wegener G,Bjarkam CR

S-SCAM/MAGI-2 is an essential synaptic scaffolding molecule for the GluA2-containing maintenance pool of AMPA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience32(20)6967-80(2012 May)
Danielson E,Zhang N,Metallo J,Kaleka K,Shin SM,Gerges N,Lee SH

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.
American journal of physiology. Renal physiology300(2)F549-60(2011 Feb)
Babayeva S,Zilber Y,Torban E