Cdc42bpb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdc42bpb
Entrez Gene ID	113960
Full Name	CDC42 binding protein kinase beta
General protein information	Preferred Names CDC42 binding protein kinase beta Names serine/threonine-protein kinase MRCK beta CDC42 binding protein kinase beta (DMPK-like) Cdc42-binding protein kinase beta DMPK-like beta MRCK beta myotonic dystrophy kinase-related CDC42-binding kinase beta myotonic dystrophy protein kinase-like beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32
Summary	serine/threonine protein kinase; mediates myosin light chain phosphorylation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006240562.3	XP_006240624.1	serine/threonine-protein kinase MRCK beta isoform X1
NM_053620.3	NP_446072.2	serine/threonine-protein kinase MRCK beta

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CDC42BPB	XP_005623889.1
Bos taurus (cattle)	CDC42BPB	XP_003587632.2
Danio rerio (zebrafish)	cdc42bpb	NP_001038590.1
Xenopus tropicalis (tropical clawed frog)	cdc42bpb	XP_004917233.1
Homo sapiens (human)	CDC42BPB	NP_006026.3
Pan troglodytes (chimpanzee)	CDC42BPB	XP_510180.2
	LOC695720	XP_002805265.1
Mus musculus (house mouse)	Cdc42bpb	NP_898837.2
Rattus norvegicus (Norway rat)	Cdc42bpb	NP_446072.2
Gallus gallus (chicken)	CDC42BPB	XP_004936409.1

Gene Ontology
Bibliography

Related articles in PubMed

CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.
Lant B, Yu B, Goudreault M, Holmyard D, Knight JD, Xu P, Zhao L, Chin K, Wallace E, Zhen M, Gingras AC, Derry WB
Nature communications66449(2015 Mar)

Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.
Lee IC, Leung T, Tan I
The Journal of biological chemistry289(39)26989-7003(2014 Sep)

Co-crystal structures of inhibitors with MRCK?, a key regulator of tumor cell invasion.
Heikkila T, Wheatley E, Crighton D, Schroder E, Boakes A, Kaye SJ, Mezna M, Pang L, Rushbrooke M, Turnbull A, Olson MF
PloS one6(9)e24825(2011)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.
Tan I, Yong J, Dong JM, Lim L, Leung T
Cell135(1)123-36(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study reports that MRCK and myosin II-related MYO18A linked by the adaptor protein LRAP35a form a functional tripartite complex, which is responsible for the assembly of lamellar actomyosin bundles and of a subnuclear actomyosin network.
Title: A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.

The following Cdc42bpb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc42bpb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10106	NM_053620.3 Latest version!	Rattus norvegicus CDC42 binding protein kinase beta (Cdc42bpb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
ORa29622	XM_006240562.3 Latest version!	Rattus norvegicus CDC42 binding protein kinase beta (Cdc42bpb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdc42bpb ( NM_053620.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446072.2 Rattus norvegicus CDC42 binding protein kinase beta (Cdc42bpb), mRNA.

Price & Availability↑

CloneID	ORa10106
Clone ID Related Accession (Same CDS sequence)	NM_053620.3
Accession Version	NM_053620.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5142bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase MRCK beta
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY277590.1 and CB748377.1. On Sep 26, 2005 this sequence version replaced NM_053620.2. ##Evidence-Data-START## Transcript exon combination :: AY277590.1, AF021936.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC 
AATGAGAGCT CCCTGAGCGT GGAGACGCTG CTGGACGTGC TGGTGTGCCT TTACACCGAG 
TGCAGCCACT CGGCGCTGCG CCGCGACAAG TATGTGGCGG AGTTCCTCGA GTGGGCTAAG 
CCATTCACCC AGCTCGTGAA GGACATGCAG CTTCATCGGG AGGACTTTGA GATCATCAAA 
GTGATTGGAA GAGGAGCTTT TGGTGAGGTT GCTGTTGTCA AAATGAAGAA CACTGAACGA 
ATTTATGCAA TGAAAATTCT CAACAAATGG GAGATGCTAA AGAGAGCAGA GACAGCTTGC 
TTTCGAGAAG AGAGGGATGT GCTGGTGAAC GGTGACTGCC AGTGGATCAC TGCGCTACAC 
TACGCCTTTC AAGATGAGAA CTACCTGTAC TTGGTTATGG ATTACTATGT GGGTGGTGAC 
TTGCTGACCC TGCTGAGTAA GTTTGAAGAC AAACTTCCAG AAGACATGGC GAGGTTCTAC 
ATTGGCGAGA TGGTGTTGGC CATCGACTCG ATCCACCAGC TCCACTATGT GCACAGAGAC 
ATTAAACCCG ACAACGTCCT TCTGGATGTC AACGGTCACA TCCGCCTGGC TGACTTTGGC 
TCGTGCTTGA AGATGAACGA TGACGGCACT GTTCAGTCTT CCGTGGCTGT GGGCACACCT 
GACTACATCT CACCAGAGAT CCTGCAGGCC ATGGAGGATG GCATGGGCAA ATACGGGCCC 
GAGTGTGACT GGTGGTCCCT GGGCGTCTGC ATGTATGAGA TGCTGTATGG AGAAACGCCA 
TTTTATGCAG AGTCTCTGGT GGAGACATAT GGAAAGATCA TGAACCACGA GGAGCGGTTT 
CAGTTCCCAT CCCACGTCAC TGACGTCTCT GAAGAAGCGA AAGACCTCAT CCAGAGACTA 
ATATGCAGCA GAGAGCGCCG GCTCGGGCAG AACGGGATAG AGGACTTTAA GAAACATGCA 
TTCTTTGAAG GTCTAAATTG GGAAAATATA CGGAACCTGG AAGCACCCTA CATTCCCGAT 
GTGAGCAGCC CTTCTGACAC GTCCAACTTC GATGTGGACG ATGACGTGCT GAGAAACATC 
GAAATCTTAC CTCCCGGCTC TCACACGGGC TTCTCGGGAC TGCACCTACC CTTCATTGGC 
TTTACATTTA CGACAGAAAG CTGCTTTTCT GACCGAGGCT CTCTGAAGAG CATGATACAG 
TCTAACACGC TAACCAAAGA TGAGGATGTG CAGCGGGATT TGGAGAACAG CTTGCAGATC 
GAAGCTTACG AGCGAAGGAT ACGAAGGCTG GAACAGGAGA AGCTAGAGCT GAGCCGGAAG 
CTGCAAGAGT CCACCCAGAC TGTGCAGTCC CTTCACGGTT CCACACGGGC CCTGGGCAAC 
TCAAACCGTG ACAAGGAAAT CAAGAGGCTG AATGAAGAGC TTGAACGCAT GAAGAGTAAA 
ATGGCAGATT CAAACAGGCT CGAACGACAG CTCGAGGATA CCGTGACCCT TCGCCAGGAG 
CATGAAGACT CCACACAACG GCTGAAGGGC CTGGAGAAGC AGTACCGCCT GGCACGGCAG 
GAGAAGGAAG AATTGCACAA GCAATTGGTT GAAGCTTCAG AGCGATTGAA ATCCCAGACC 
AAAGAACTCA AAGATGCTCA TCAGCAGCGA AAACGGGCCC TGCAGGAGTT TTCAGAGCTC 
AATGAGCGCA TGGCAGAGCT GAGGTCACAG AAGCAGAAGG TGTCCCGGCA GCTCCGTGAC 
AAGGAGGAGG AGATGGAGGT GGCCATGCAG AAGATTGACT CCATGAGGCA GGATATCCGC 
AAGTCTGAGA AGTCTAGGAA AGAGCTGGAA GCTCGGCTTG AGGACGCAGT CGCTGAGGCC 
TCCAAGGAGA GGAAGCTTCG AGAGCACAGT GAGAGCTTCT CTAAGCAGAT GGAGCGCGAG 
CTCGAGACCC TCAAGGTGAA GCAAGGAGGC CGGGGGCCGG GTGCCACGTT AGAACATCAG 
CAGGAGATCT CCAAAATCAG GTCAGAGCTT GAGAAGAAAG TCTTGTTCTA TGAGGAGGAG 
TTGGTCCGCC GAGAGGCCTC CCATGTGCTA GAAGTAAAGA ATGTGAAGAA GGAGGTGCAC 
GAATCTGAAA GCCACCAGTT GGCCCTGCAG AAAGAGGTCC TGATGCTGAA AGATAAGTTA 
GAAAAGTCAA AACGAGAACG GCACAGTGAG ATGGAGGAGG CCATAGGTGC CATGAAAGAC 
AAGTACGAAC GGGAGAGGGC CATGCTGTTC GACGAGAACA AGAAGTTAAC AGCAGAAAAC 
GAAAAGCTCT GTTCCTTTGT GGATAAACTA ACAGCCCAAA ACAGACAGCT GGAGGACGAG 
CTGCAGGACC TGGCCTCCAA GAAGGAGTCG GTCGCTCACT GGGAGGCGCA GATTGCAGAG 
ATTATTCAGT GGGTCAGCGA TGAGAAAGAT GCCAGAGGCT ACCTTCAAGC ACTTGCTTCT 
AAGATGACCG AAGAGCTTGA GACTTTGAGA AGCTCTAGTT TGGGATCCAG GACACTGGAC 
CCACTCTGGA AGGTCCGTCG GAGCCAGAAG CTGGACATGT CTGCGCGGCT GGAGTTGCAG 
TCCGCTCTCG AGGCAGAGAT CCGTGCCAAG CAGCTGGTTC ACGAGGAGCT GAGGAAGGTC 
AAAGACACCA GCCTAGCCTT CGAAAGCAAA CTGAAGGAGT CAGAAGCCAA AAACAGGGAA 
TTATTAGAAG AAATGCAAAG TCTGAAGAAA AGGATGGAAG AAAAATTTAG AGCAGATACA 
GGGCTCAAAC TTCCAGATTT CCAGGATCCT ATCTTTGAGT ACTTCAACAC TGCTCCTCTT 
GCACATGACC TGACTTTTAG AACTAGCTCA GCTAGTGATC AGGAAACACA GGCTTCAAAG 
TTGGACTTGT CCCCATCAGT GTCTGTGGCC ACAAGCACAG AACAGCAGGA GGATGCGGCT 
CGTTCACAGC AGAGGCCGTC TACTGTGCCG CTGCCCAACA CACAGGCCCT CGCCATGGCT 
GGACCAAAGC CCAAGGCACA CCAGTTCAGC ATCAAGTCCT TCCCCAGCCC CACCCAGTGT 
AGCCACTGTA CGTCCTTGAT GGTTGGGCTG ATCCGACAGG GCTATGCCTG TGAGGTCTGC 
GCGTTTTCCT GCCATGTGTC CTGCAAAGAC AGCGCTCCCC AGGTGTGCCC CATACCTCCT 
GAGCAGTCCA AGCGGCCTCT CGGCGTAGAC GTGCAGAGGG GCATAGGCAC AGCCTACAAG 
GGCTACGTCA AGGTCCCGAA GCCCACAGGC GTGAAGAAAG GGTGGCAGCG GGCTTACGCA 
GTGGTCTGTG ACTGCAAGCT CTTCCTGTAC GACCTGCCAG AAGGGAAGTC CACCCAGCCT 
GGGGTCATCG CCAGTCAAGT CTTAGACCTC AGAGATGACG AGTTTGCTGT GAGCTCAGTC 
CTGGCCTCAG ATGTCATCCA TGCTACACGC CGAGACATCC CGTGTATATT CAGGGTGACG 
GCCTCTCTCT TAGGTTCACC TTCTAAGACC AGCTCACTGC TCATCCTGAC AGAGAACGAG 
AATGAAAAGA GGAAGTGGGT TGGGATCCTG GAAGGGCTGC AGGCTATCCT CCACAAGAAC 
CGGCTGAGGA GCCAGGTGGT GCACGTGGCA CAGGAAGCGT ACGACAGCTC ACTGCCGCTC 
ATCAAGACCG TCCTGGCTGC CGCTATTGTG GATGGAGACA GAATTGCGGT CGGCCTGGAA 
GAAGGGCTCT ACGTCATTGA GCTCACCCGA GATGTGATCG TCCGCGCTGC TGACTGCAAG 
AAGGTATACC AGATCGAGCT GGCGCCCAAG GAGAAGCTCA TCCTCCTCCT CTGTGGCCGG 
AACCACCACG TGCACCTCTA CCCCTGGACC TCCTTCGATG GAGCAGAAGC TAGCAACTTT 
GACATCAAGC TCCCAGAAAC GAAGGGCTGC CAGCTCATAG CAACAGGGAC GCTGAGGAAG 
AGCTCGTCCA CCTGCCTGTT TGTCGCCGTG AAGCGGCTGG TCCTTTGCTA CGAGATCCAG 
AGAACTAAGC CTTTCCACCG GAAGTTCAAT GAGATCGTGG CCCCGGGACA TGTGCAGTGG 
ATGGCCATGT TCAAGGACAG GCTCTGTGTT GGCTACCCCT CCGGGTTCTC TCTGTTGAGC 
ATCCAGGGGG ACGGGCAGCC TCTAGACCTG GTAAATCCCG CTGACCCCTC GCTCGCGTTC 
CTCTCACAGC AGTCTTTCGA TGCCCTCTGT GCTGTAGAGC TCAAAAGTGA GGAGTACCTG 
CTCTGCTTCA GCCACATGGG ACTGTACGTG GACCCTCAAG GTCGGAGGTC ACGCACGCAG 
GAGCTCATGT GGCCTGCGGC TCCTGTCGCC TGTAGTTGCA GCTCCTCCCA CGTCACGGTG 
TACAGCGAAT ACGGGGTGGA TGTCTTCGAC GTGCGCACCA TGGAGTGGGT TCAGACCATC 
GGCCTGCGGA GGATAAGACC TCTGAACTCT GATGGTAGCC TCAACCTGCT GGGCTGTGAG 
CCCCCACGCC TCATCTACTT CAAAAACAAG TTCTCAGGCA CCGTCCTCAA TGTGCCCGAT 
ACCTCGGACA ACAGCAAGAA GCAGATGCTG CGGACGCGGA GCAAACGGCG CTTCGTCTTC 
AAGGTTCCAG AGGAAGAGAG GCTGCAGCAG CGGCGAGAGA TGCTCAGAGA CCCGGAACTG 
AGATCCAAAA TGATATCCAA TCCGACCAAC TTCAACCACG TGGCTCACAT GGGCCCTGGC 
GATGGGATGC AGGTGCTCAT GGACCTGCCT CTGAGTGCTG CGCCCACAGC CCAGGAGGAA 
AAGCAGGGTC CTGCCCCAAC AGGCCTCCCT CGGCAGCTCC CATCCAGGAA CAAGCCCTAT 
GTCTCATGGC CGTCCTCAGG TGGGTCTGAG CCTGGAGTGC CTGTGCCTCT GAGGAGCATG 
TCTGACCCCG ACCAGGATTT TGACAAAGAG CCTGACTCTG ACTCCACGAA GCACTCGACT 
CCGTCCAACA GCTCCAACCC TAGCGGCCCC CCGAGCCCCA ACTCACCGCA CCGGAGCCAG 
CTCCCTCTGG AAGGCCTGGA CCAGCCAGCC TGCGACGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446072.2
CDS	89..5230
Translation	MSAKVRLKKLEQLLLDGPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSMIQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTRALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQYRLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVSRQLRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSKQMERELETLKVKQGGRGPGATLEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHESESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGAMKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVHEELRKVKDTSLAFESKLKESEAKNRELLEEMQSLKKRMEEKFRADTGLKLPDFQDPIFEYFNTAPLAHDLTFRTSSASDQETQASKLDLSPSVSVATSTEQQEDAARSQQRPSTVPLPNTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFAVSSVLASDVIHATRRDIPCIFRVTASLLGSPSKTSSLLILTENENEKRKWVGILEGLQAILHKNRLRSQVVHVAQEAYDSSLPLIKTVLAAAIVDGDRIAVGLEEGLYVIELTRDVIVRAADCKKVYQIELAPKEKLILLLCGRNHHVHLYPWTSFDGAEASNFDIKLPETKGCQLIATGTLRKSSSTCLFVAVKRLVLCYEIQRTKPFHRKFNEIVAPGHVQWMAMFKDRLCVGYPSGFSLLSIQGDGQPLDLVNPADPSLAFLSQQSFDALCAVELKSEEYLLCFSHMGLYVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGCEPPRLIYFKNKFSGTVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPTAQEEKQGPAPTGLPRQLPSRNKPYVSWPSSGGSEPGVPVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLDQPACDA

Target ORF information:

RefSeq Version	NM_053620.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDC42 binding protein kinase beta (Cdc42bpb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053620.3

ORF Insert Sequence:

ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC 
AATGAGAGCT CCCTGAGCGT GGAGACGCTG CTGGACGTGC TGGTGTGCCT TTACACCGAG 
TGCAGCCACT CGGCGCTGCG CCGCGACAAG TATGTGGCGG AGTTCCTCGA GTGGGCTAAG 
CCATTCACCC AGCTCGTGAA GGACATGCAG CTTCATCGGG AGGACTTTGA GATCATCAAA 
GTGATTGGAA GAGGAGCTTT TGGTGAGGTT GCTGTTGTCA AAATGAAGAA CACTGAACGA 
ATTTATGCAA TGAAAATTCT CAACAAATGG GAGATGCTAA AGAGAGCAGA GACAGCTTGC 
TTTCGAGAAG AGAGGGATGT GCTGGTGAAC GGTGACTGCC AGTGGATCAC TGCGCTACAC 
TACGCCTTTC AAGATGAGAA CTACCTGTAC TTGGTTATGG ATTACTATGT GGGTGGTGAC 
TTGCTGACCC TGCTGAGTAA GTTTGAAGAC AAACTTCCAG AAGACATGGC GAGGTTCTAC 
ATTGGCGAGA TGGTGTTGGC CATCGACTCG ATCCACCAGC TCCACTATGT GCACAGAGAC 
ATTAAACCCG ACAACGTCCT TCTGGATGTC AACGGTCACA TCCGCCTGGC TGACTTTGGC 
TCGTGCTTGA AGATGAACGA TGACGGCACT GTTCAGTCTT CCGTGGCTGT GGGCACACCT 
GACTACATCT CACCAGAGAT CCTGCAGGCC ATGGAGGATG GCATGGGCAA ATACGGGCCC 
GAGTGTGACT GGTGGTCCCT GGGCGTCTGC ATGTATGAGA TGCTGTATGG AGAAACGCCA 
TTTTATGCAG AGTCTCTGGT GGAGACATAT GGAAAGATCA TGAACCACGA GGAGCGGTTT 
CAGTTCCCAT CCCACGTCAC TGACGTCTCT GAAGAAGCGA AAGACCTCAT CCAGAGACTA 
ATATGCAGCA GAGAGCGCCG GCTCGGGCAG AACGGGATAG AGGACTTTAA GAAACATGCA 
TTCTTTGAAG GTCTAAATTG GGAAAATATA CGGAACCTGG AAGCACCCTA CATTCCCGAT 
GTGAGCAGCC CTTCTGACAC GTCCAACTTC GATGTGGACG ATGACGTGCT GAGAAACATC 
GAAATCTTAC CTCCCGGCTC TCACACGGGC TTCTCGGGAC TGCACCTACC CTTCATTGGC 
TTTACATTTA CGACAGAAAG CTGCTTTTCT GACCGAGGCT CTCTGAAGAG CATGATACAG 
TCTAACACGC TAACCAAAGA TGAGGATGTG CAGCGGGATT TGGAGAACAG CTTGCAGATC 
GAAGCTTACG AGCGAAGGAT ACGAAGGCTG GAACAGGAGA AGCTAGAGCT GAGCCGGAAG 
CTGCAAGAGT CCACCCAGAC TGTGCAGTCC CTTCACGGTT CCACACGGGC CCTGGGCAAC 
TCAAACCGTG ACAAGGAAAT CAAGAGGCTG AATGAAGAGC TTGAACGCAT GAAGAGTAAA 
ATGGCAGATT CAAACAGGCT CGAACGACAG CTCGAGGATA CCGTGACCCT TCGCCAGGAG 
CATGAAGACT CCACACAACG GCTGAAGGGC CTGGAGAAGC AGTACCGCCT GGCACGGCAG 
GAGAAGGAAG AATTGCACAA GCAATTGGTT GAAGCTTCAG AGCGATTGAA ATCCCAGACC 
AAAGAACTCA AAGATGCTCA TCAGCAGCGA AAACGGGCCC TGCAGGAGTT TTCAGAGCTC 
AATGAGCGCA TGGCAGAGCT GAGGTCACAG AAGCAGAAGG TGTCCCGGCA GCTCCGTGAC 
AAGGAGGAGG AGATGGAGGT GGCCATGCAG AAGATTGACT CCATGAGGCA GGATATCCGC 
AAGTCTGAGA AGTCTAGGAA AGAGCTGGAA GCTCGGCTTG AGGACGCAGT CGCTGAGGCC 
TCCAAGGAGA GGAAGCTTCG AGAGCACAGT GAGAGCTTCT CTAAGCAGAT GGAGCGCGAG 
CTCGAGACCC TCAAGGTGAA GCAAGGAGGC CGGGGGCCGG GTGCCACGTT AGAACATCAG 
CAGGAGATCT CCAAAATCAG GTCAGAGCTT GAGAAGAAAG TCTTGTTCTA TGAGGAGGAG 
TTGGTCCGCC GAGAGGCCTC CCATGTGCTA GAAGTAAAGA ATGTGAAGAA GGAGGTGCAC 
GAATCTGAAA GCCACCAGTT GGCCCTGCAG AAAGAGGTCC TGATGCTGAA AGATAAGTTA 
GAAAAGTCAA AACGAGAACG GCACAGTGAG ATGGAGGAGG CCATAGGTGC CATGAAAGAC 
AAGTACGAAC GGGAGAGGGC CATGCTGTTC GACGAGAACA AGAAGTTAAC AGCAGAAAAC 
GAAAAGCTCT GTTCCTTTGT GGATAAACTA ACAGCCCAAA ACAGACAGCT GGAGGACGAG 
CTGCAGGACC TGGCCTCCAA GAAGGAGTCG GTCGCTCACT GGGAGGCGCA GATTGCAGAG 
ATTATTCAGT GGGTCAGCGA TGAGAAAGAT GCCAGAGGCT ACCTTCAAGC ACTTGCTTCT 
AAGATGACCG AAGAGCTTGA GACTTTGAGA AGCTCTAGTT TGGGATCCAG GACACTGGAC 
CCACTCTGGA AGGTCCGTCG GAGCCAGAAG CTGGACATGT CTGCGCGGCT GGAGTTGCAG 
TCCGCTCTCG AGGCAGAGAT CCGTGCCAAG CAGCTGGTTC ACGAGGAGCT GAGGAAGGTC 
AAAGACACCA GCCTAGCCTT CGAAAGCAAA CTGAAGGAGT CAGAAGCCAA AAACAGGGAA 
TTATTAGAAG AAATGCAAAG TCTGAAGAAA AGGATGGAAG AAAAATTTAG AGCAGATACA 
GGGCTCAAAC TTCCAGATTT CCAGGATCCT ATCTTTGAGT ACTTCAACAC TGCTCCTCTT 
GCACATGACC TGACTTTTAG AACTAGCTCA GCTAGTGATC AGGAAACACA GGCTTCAAAG 
TTGGACTTGT CCCCATCAGT GTCTGTGGCC ACAAGCACAG AACAGCAGGA GGATGCGGCT 
CGTTCACAGC AGAGGCCGTC TACTGTGCCG CTGCCCAACA CACAGGCCCT CGCCATGGCT 
GGACCAAAGC CCAAGGCACA CCAGTTCAGC ATCAAGTCCT TCCCCAGCCC CACCCAGTGT 
AGCCACTGTA CGTCCTTGAT GGTTGGGCTG ATCCGACAGG GCTATGCCTG TGAGGTCTGC 
GCGTTTTCCT GCCATGTGTC CTGCAAAGAC AGCGCTCCCC AGGTGTGCCC CATACCTCCT 
GAGCAGTCCA AGCGGCCTCT CGGCGTAGAC GTGCAGAGGG GCATAGGCAC AGCCTACAAG 
GGCTACGTCA AGGTCCCGAA GCCCACAGGC GTGAAGAAAG GGTGGCAGCG GGCTTACGCA 
GTGGTCTGTG ACTGCAAGCT CTTCCTGTAC GACCTGCCAG AAGGGAAGTC CACCCAGCCT 
GGGGTCATCG CCAGTCAAGT CTTAGACCTC AGAGATGACG AGTTTGCTGT GAGCTCAGTC 
CTGGCCTCAG ATGTCATCCA TGCTACACGC CGAGACATCC CGTGTATATT CAGGGTGACG 
GCCTCTCTCT TAGGTTCACC TTCTAAGACC AGCTCACTGC TCATCCTGAC AGAGAACGAG 
AATGAAAAGA GGAAGTGGGT TGGGATCCTG GAAGGGCTGC AGGCTATCCT CCACAAGAAC 
CGGCTGAGGA GCCAGGTGGT GCACGTGGCA CAGGAAGCGT ACGACAGCTC ACTGCCGCTC 
ATCAAGACCG TCCTGGCTGC CGCTATTGTG GATGGAGACA GAATTGCGGT CGGCCTGGAA 
GAAGGGCTCT ACGTCATTGA GCTCACCCGA GATGTGATCG TCCGCGCTGC TGACTGCAAG 
AAGGTATACC AGATCGAGCT GGCGCCCAAG GAGAAGCTCA TCCTCCTCCT CTGTGGCCGG 
AACCACCACG TGCACCTCTA CCCCTGGACC TCCTTCGATG GAGCAGAAGC TAGCAACTTT 
GACATCAAGC TCCCAGAAAC GAAGGGCTGC CAGCTCATAG CAACAGGGAC GCTGAGGAAG 
AGCTCGTCCA CCTGCCTGTT TGTCGCCGTG AAGCGGCTGG TCCTTTGCTA CGAGATCCAG 
AGAACTAAGC CTTTCCACCG GAAGTTCAAT GAGATCGTGG CCCCGGGACA TGTGCAGTGG 
ATGGCCATGT TCAAGGACAG GCTCTGTGTT GGCTACCCCT CCGGGTTCTC TCTGTTGAGC 
ATCCAGGGGG ACGGGCAGCC TCTAGACCTG GTAAATCCCG CTGACCCCTC GCTCGCGTTC 
CTCTCACAGC AGTCTTTCGA TGCCCTCTGT GCTGTAGAGC TCAAAAGTGA GGAGTACCTG 
CTCTGCTTCA GCCACATGGG ACTGTACGTG GACCCTCAAG GTCGGAGGTC ACGCACGCAG 
GAGCTCATGT GGCCTGCGGC TCCTGTCGCC TGTAGTTGCA GCTCCTCCCA CGTCACGGTG 
TACAGCGAAT ACGGGGTGGA TGTCTTCGAC GTGCGCACCA TGGAGTGGGT TCAGACCATC 
GGCCTGCGGA GGATAAGACC TCTGAACTCT GATGGTAGCC TCAACCTGCT GGGCTGTGAG 
CCCCCACGCC TCATCTACTT CAAAAACAAG TTCTCAGGCA CCGTCCTCAA TGTGCCCGAT 
ACCTCGGACA ACAGCAAGAA GCAGATGCTG CGGACGCGGA GCAAACGGCG CTTCGTCTTC 
AAGGTTCCAG AGGAAGAGAG GCTGCAGCAG CGGCGAGAGA TGCTCAGAGA CCCGGAACTG 
AGATCCAAAA TGATATCCAA TCCGACCAAC TTCAACCACG TGGCTCACAT GGGCCCTGGC 
GATGGGATGC AGGTGCTCAT GGACCTGCCT CTGAGTGCTG CGCCCACAGC CCAGGAGGAA 
AAGCAGGGTC CTGCCCCAAC AGGCCTCCCT CGGCAGCTCC CATCCAGGAA CAAGCCCTAT 
GTCTCATGGC CGTCCTCAGG TGGGTCTGAG CCTGGAGTGC CTGTGCCTCT GAGGAGCATG 
TCTGACCCCG ACCAGGATTT TGACAAAGAG CCTGACTCTG ACTCCACGAA GCACTCGACT 
CCGTCCAACA GCTCCAACCC TAGCGGCCCC CCGAGCCCCA ACTCACCGCA CCGGAGCCAG 
CTCCCTCTGG AAGGCCTGGA CCAGCCAGCC TGCGACGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cdc42bpb ( XM_006240562.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240624.1 Rattus norvegicus CDC42 binding protein kinase beta (Cdc42bpb), transcript variant X1, mRNA.

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CloneID	ORa29622
Clone ID Related Accession (Same CDS sequence)	XM_006240562.3
Accession Version	XM_006240562.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5193bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase MRCK beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240562.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC 
AATGAGAGCT CCCTGAGCGT GGAGACGCTG CTGGACGTGC TGGTGTGCCT TTACACCGAG 
TGCAGCCACT CGGCGCTGCG CCGCGACAAG TATGTGGCGG AGTTCCTCGA GTGGGCTAAG 
CCATTCACCC AGCTCGTGAA GGACATGCAG CTTCATCGGG AGGACTTTGA GATCATCAAA 
GTGATTGGAA GAGGAGCTTT TGGTGAGGTT GCTGTTGTCA AAATGAAGAA CACTGAACGA 
ATTTATGCAA TGAAAATTCT CAACAAATGG GAGATGCTAA AGAGAGCAGA GACAGCTTGC 
TTTCGAGAAG AGAGGGATGT GCTGGTGAAC GGTGACTGCC AGTGGATCAC TGCGCTACAC 
TACGCCTTTC AAGATGAGAA CTACCTGTAC TTGGTTATGG ATTACTATGT GGGTGGTGAC 
TTGCTGACCC TGCTGAGTAA GTTTGAAGAC AAACTTCCAG AAGACATGGC GAGGTTCTAC 
ATTGGCGAGA TGGTGTTGGC CATCGACTCG ATCCACCAGC TCCACTATGT GCACAGAGAC 
ATTAAACCCG ACAACGTCCT TCTGGATGTC AACGGTCACA TCCGCCTGGC TGACTTTGGC 
TCGTGCTTGA AGATGAACGA TGACGGCACT GTTCAGTCTT CCGTGGCTGT GGGCACACCT 
GACTACATCT CACCAGAGAT CCTGCAGGCC ATGGAGGATG GCATGGGCAA ATACGGGCCC 
GAGTGTGACT GGTGGTCCCT GGGCGTCTGC ATGTATGAGA TGCTGTATGG AGAAACGCCA 
TTTTATGCAG AGTCTCTGGT GGAGACATAT GGAAAGATCA TGAACCACGA GGAGCGGTTT 
CAGTTCCCAT CCCACGTCAC TGACGTCTCT GAAGAAGCGA AAGACCTCAT CCAGAGACTA 
ATATGCAGCA GAGAGCGCCG GCTCGGGCAG AACGGGATAG AGGACTTTAA GAAACATGCA 
TTCTTTGAAG GTCTAAATTG GGAAAATATA CGGAACCTGG AAGCACCCTA CATTCCCGAT 
GTGAGCAGCC CTTCTGACAC GTCCAACTTC GATGTGGACG ATGACGTGCT GAGAAACATC 
GAAATCTTAC CTCCCGGCTC TCACACGGGC TTCTCGGGAC TGCACCTACC CTTCATTGGC 
TTTACATTTA CGACAGAAAG CTGCTTTTCT GACCGAGGCT CTCTGAAGAG CATGATACAG 
TCTAACACGC TAACCAAAGA TGAGGATGTG CAGCGGGATT TGGAGAACAG CTTGCAGATC 
GAAGCTTACG AGCGAAGGAT ACGAAGGCTG GAACAGGAGA AGCTAGAGCT GAGCCGGAAG 
CTGCAAGAGT CCACCCAGAC TGTGCAGTCC CTTCACGGTT CCACACGGGC CCTGGGCAAC 
TCAAACCGTG ACAAGGAAAT CAAGAGGCTG AATGAAGAGC TTGAACGCAT GAAGAGTAAA 
ATGGCAGATT CAAACAGGCT CGAACGACAG CTCGAGGATA CCGTGACCCT TCGCCAGGAG 
CATGAAGACT CCACACAACG GCTGAAGGGC CTGGAGAAGC AGTACCGCCT GGCACGGCAG 
GAGAAGGAAG AATTGCACAA GCAATTGGTT GAAGCTTCAG AGCGATTGAA ATCCCAGACC 
AAAGAACTCA AAGATGCTCA TCAGCAGCGA AAACGGGCCC TGCAGGAGTT TTCAGAGCTC 
AATGAGCGCA TGGCAGAGCT GAGGTCACAG AAGCAGAAGG TGTCCCGGCA GCTCCGTGAC 
AAGGAGGAGG AGATGGAGGT GGCCATGCAG AAGATTGACT CCATGAGGCA GGATATCCGC 
AAGTCTGAGA AGTCTAGGAA AGAGCTGGAA GCTCGGCTTG AGGACGCAGT CGCTGAGGCC 
TCCAAGGAGA GGAAGCTTCG AGAGCACAGT GAGAGCTTCT CTAAGCAGAT GGAGCGCGAG 
CTCGAGACCC TCAAGGTGAA GCAAGGAGGC CGGGGGCCGG GTGCCACGTT AGAACATCAG 
CAGGAGATCT CCAAAATCAG GTCAGAGCTT GAGAAGAAAG TCTTGTTCTA TGAGGAGGAG 
TTGGTCCGCC GAGAGGCCTC CCATGTGCTA GAAGTAAAGA ATGTGAAGAA GGAGGTGCAC 
GAATCTGAAA GCCACCAGTT GGCCCTGCAG AAAGAGGTCC TGATGCTGAA AGATAAGTTA 
GAAAAGTCAA AACGAGAACG GCACAGTGAG ATGGAGGAGG CCATAGGTGC CATGAAAGAC 
AAGTACGAAC GGGAGAGGGC CATGCTGTTC GACGAGAACA AGAAGTTAAC AGCAGAAAAC 
GAAAAGCTCT GTTCCTTTGT GGATAAACTA ACAGCCCAAA ACAGACAGCT GGAGGACGAG 
CTGCAGGACC TGGCCTCCAA GAAGGAGTCG GTCGCTCACT GGGAGGCGCA GATTGCAGAG 
ATTATTCAGT GGGTCAGCGA TGAGAAAGAT GCCAGAGGCT ACCTTCAAGC ACTTGCTTCT 
AAGATGACCG AAGAGCTTGA GACTTTGAGA AGCTCTAGTT TGGGATCCAG GACACTGGAC 
CCACTCTGGA AGGTCCGTCG GAGCCAGAAG CTGGACATGT CTGCGCGGCT GGAGTTGCAG 
TCCGCTCTCG AGGCAGAGAT CCGTGCCAAG CAGCTGGTTC ACGAGGAGCT GAGGAAGGTC 
AAAGACACCA GCCTAGCCTT CGAAAGCAAA CTGAAGGAGT CAGAAGCCAA AAACAGGGAA 
TTATTAGAAG AAATGCAAAG TCTGAAGAAA AGGATGGAAG AAAAATTTAG AGCAGATACA 
GGGCTCAAAC TTCCAGATTT CCAGGATCCT ATCTTTGAGT ACTTCAACAC TGCTCCTCTT 
GCACATGACC TGACTTTTAG AGACTCGCTC TCCTCCTCAT CTGCATCTTC TCTGCTAGCC 
TTGTGGGAGG ACACTAGCTC AGCTAGTGAT CAGGAAACAC AGGCTTCAAA GTTGGACTTG 
TCCCCATCAG TGTCTGTGGC CACAAGCACA GAACAGCAGG AGGATGCGGC TCGTTCACAG 
CAGAGGCCGT CTACTGTGCC GCTGCCCAAC ACACAGGCCC TCGCCATGGC TGGACCAAAG 
CCCAAGGCAC ACCAGTTCAG CATCAAGTCC TTCCCCAGCC CCACCCAGTG TAGCCACTGT 
ACGTCCTTGA TGGTTGGGCT GATCCGACAG GGCTATGCCT GTGAGGTCTG CGCGTTTTCC 
TGCCATGTGT CCTGCAAAGA CAGCGCTCCC CAGGTGTGCC CCATACCTCC TGAGCAGTCC 
AAGCGGCCTC TCGGCGTAGA CGTGCAGAGG GGCATAGGCA CAGCCTACAA GGGCTACGTC 
AAGGTCCCGA AGCCCACAGG CGTGAAGAAA GGGTGGCAGC GGGCTTACGC AGTGGTCTGT 
GACTGCAAGC TCTTCCTGTA CGACCTGCCA GAAGGGAAGT CCACCCAGCC TGGGGTCATC 
GCCAGTCAAG TCTTAGACCT CAGAGATGAC GAGTTTGCTG TGAGCTCAGT CCTGGCCTCA 
GATGTCATCC ATGCTACACG CCGAGACATC CCGTGTATAT TCAGGGTGAC GGCCTCTCTC 
TTAGGTTCAC CTTCTAAGAC CAGCTCACTG CTCATCCTGA CAGAGAACGA GAATGAAAAG 
AGGAAGTGGG TTGGGATCCT GGAAGGGCTG CAGGCTATCC TCCACAAGAA CCGGCTGAGG 
AGCCAGGTGG TGCACGTGGC ACAGGAAGCG TACGACAGCT CACTGCCGCT CATCAAGACC 
GTCCTGGCTG CCGCTATTGT GGATGGAGAC AGAATTGCGG TCGGCCTGGA AGAAGGGCTC 
TACGTCATTG AGCTCACCCG AGATGTGATC GTCCGCGCTG CTGACTGCAA GAAGGTATAC 
CAGATCGAGC TGGCGCCCAA GGAGAAGCTC ATCCTCCTCC TCTGTGGCCG GAACCACCAC 
GTGCACCTCT ACCCCTGGAC CTCCTTCGAT GGAGCAGAAG CTAGCAACTT TGACATCAAG 
CTCCCAGAAA CGAAGGGCTG CCAGCTCATA GCAACAGGGA CGCTGAGGAA GAGCTCGTCC 
ACCTGCCTGT TTGTCGCCGT GAAGCGGCTG GTCCTTTGCT ACGAGATCCA GAGAACTAAG 
CCTTTCCACC GGAAGTTCAA TGAGATCGTG GCCCCGGGAC ATGTGCAGTG GATGGCCATG 
TTCAAGGACA GGCTCTGTGT TGGCTACCCC TCCGGGTTCT CTCTGTTGAG CATCCAGGGG 
GACGGGCAGC CTCTAGACCT GGTAAATCCC GCTGACCCCT CGCTCGCGTT CCTCTCACAG 
CAGTCTTTCG ATGCCCTCTG TGCTGTAGAG CTCAAAAGTG AGGAGTACCT GCTCTGCTTC 
AGCCACATGG GACTGTACGT GGACCCTCAA GGTCGGAGGT CACGCACGCA GGAGCTCATG 
TGGCCTGCGG CTCCTGTCGC CTGTAGTTGC AGCTCCTCCC ACGTCACGGT GTACAGCGAA 
TACGGGGTGG ATGTCTTCGA CGTGCGCACC ATGGAGTGGG TTCAGACCAT CGGCCTGCGG 
AGGATAAGAC CTCTGAACTC TGATGGTAGC CTCAACCTGC TGGGCTGTGA GCCCCCACGC 
CTCATCTACT TCAAAAACAA GTTCTCAGGC ACCGTCCTCA ATGTGCCCGA TACCTCGGAC 
AACAGCAAGA AGCAGATGCT GCGGACGCGG AGCAAACGGC GCTTCGTCTT CAAGGTTCCA 
GAGGAAGAGA GGCTGCAGCA GCGGCGAGAG ATGCTCAGAG ACCCGGAACT GAGATCCAAA 
ATGATATCCA ATCCGACCAA CTTCAACCAC GTGGCTCACA TGGGCCCTGG CGATGGGATG 
CAGGTGCTCA TGGACCTGCC TCTGAGTGCT GCGCCCACAG CCCAGGAGGA AAAGCAGGGT 
CCTGCCCCAA CAGGCCTCCC TCGGCAGCTC CCATCCAGGA ACAAGCCCTA TGTCTCATGG 
CCGTCCTCAG GTGGGTCTGA GCCTGGAGTG CCTGTGCCTC TGAGGAGCAT GTCTGACCCC 
GACCAGGATT TTGACAAAGA GCCTGACTCT GACTCCACGA AGCACTCGAC TCCGTCCAAC 
AGCTCCAACC CTAGCGGCCC CCCGAGCCCC AACTCACCGC ACCGGAGCCA GCTCCCTCTG 
GAAGGCCTGG ACCAGCCAGC CTGCGACGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240624.1
CDS	239..5431
Translation	MSAKVRLKKLEQLLLDGPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSMIQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTRALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQYRLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVSRQLRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSKQMERELETLKVKQGGRGPGATLEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHESESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGAMKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVHEELRKVKDTSLAFESKLKESEAKNRELLEEMQSLKKRMEEKFRADTGLKLPDFQDPIFEYFNTAPLAHDLTFRDSLSSSSASSLLALWEDTSSASDQETQASKLDLSPSVSVATSTEQQEDAARSQQRPSTVPLPNTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFAVSSVLASDVIHATRRDIPCIFRVTASLLGSPSKTSSLLILTENENEKRKWVGILEGLQAILHKNRLRSQVVHVAQEAYDSSLPLIKTVLAAAIVDGDRIAVGLEEGLYVIELTRDVIVRAADCKKVYQIELAPKEKLILLLCGRNHHVHLYPWTSFDGAEASNFDIKLPETKGCQLIATGTLRKSSSTCLFVAVKRLVLCYEIQRTKPFHRKFNEIVAPGHVQWMAMFKDRLCVGYPSGFSLLSIQGDGQPLDLVNPADPSLAFLSQQSFDALCAVELKSEEYLLCFSHMGLYVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGCEPPRLIYFKNKFSGTVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPTAQEEKQGPAPTGLPRQLPSRNKPYVSWPSSGGSEPGVPVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLDQPACDA

Target ORF information:

RefSeq Version	XM_006240562.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDC42 binding protein kinase beta (Cdc42bpb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240562.3

ORF Insert Sequence:

ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC 
AATGAGAGCT CCCTGAGCGT GGAGACGCTG CTGGACGTGC TGGTGTGCCT TTACACCGAG 
TGCAGCCACT CGGCGCTGCG CCGCGACAAG TATGTGGCGG AGTTCCTCGA GTGGGCTAAG 
CCATTCACCC AGCTCGTGAA GGACATGCAG CTTCATCGGG AGGACTTTGA GATCATCAAA 
GTGATTGGAA GAGGAGCTTT TGGTGAGGTT GCTGTTGTCA AAATGAAGAA CACTGAACGA 
ATTTATGCAA TGAAAATTCT CAACAAATGG GAGATGCTAA AGAGAGCAGA GACAGCTTGC 
TTTCGAGAAG AGAGGGATGT GCTGGTGAAC GGTGACTGCC AGTGGATCAC TGCGCTACAC 
TACGCCTTTC AAGATGAGAA CTACCTGTAC TTGGTTATGG ATTACTATGT GGGTGGTGAC 
TTGCTGACCC TGCTGAGTAA GTTTGAAGAC AAACTTCCAG AAGACATGGC GAGGTTCTAC 
ATTGGCGAGA TGGTGTTGGC CATCGACTCG ATCCACCAGC TCCACTATGT GCACAGAGAC 
ATTAAACCCG ACAACGTCCT TCTGGATGTC AACGGTCACA TCCGCCTGGC TGACTTTGGC 
TCGTGCTTGA AGATGAACGA TGACGGCACT GTTCAGTCTT CCGTGGCTGT GGGCACACCT 
GACTACATCT CACCAGAGAT CCTGCAGGCC ATGGAGGATG GCATGGGCAA ATACGGGCCC 
GAGTGTGACT GGTGGTCCCT GGGCGTCTGC ATGTATGAGA TGCTGTATGG AGAAACGCCA 
TTTTATGCAG AGTCTCTGGT GGAGACATAT GGAAAGATCA TGAACCACGA GGAGCGGTTT 
CAGTTCCCAT CCCACGTCAC TGACGTCTCT GAAGAAGCGA AAGACCTCAT CCAGAGACTA 
ATATGCAGCA GAGAGCGCCG GCTCGGGCAG AACGGGATAG AGGACTTTAA GAAACATGCA 
TTCTTTGAAG GTCTAAATTG GGAAAATATA CGGAACCTGG AAGCACCCTA CATTCCCGAT 
GTGAGCAGCC CTTCTGACAC GTCCAACTTC GATGTGGACG ATGACGTGCT GAGAAACATC 
GAAATCTTAC CTCCCGGCTC TCACACGGGC TTCTCGGGAC TGCACCTACC CTTCATTGGC 
TTTACATTTA CGACAGAAAG CTGCTTTTCT GACCGAGGCT CTCTGAAGAG CATGATACAG 
TCTAACACGC TAACCAAAGA TGAGGATGTG CAGCGGGATT TGGAGAACAG CTTGCAGATC 
GAAGCTTACG AGCGAAGGAT ACGAAGGCTG GAACAGGAGA AGCTAGAGCT GAGCCGGAAG 
CTGCAAGAGT CCACCCAGAC TGTGCAGTCC CTTCACGGTT CCACACGGGC CCTGGGCAAC 
TCAAACCGTG ACAAGGAAAT CAAGAGGCTG AATGAAGAGC TTGAACGCAT GAAGAGTAAA 
ATGGCAGATT CAAACAGGCT CGAACGACAG CTCGAGGATA CCGTGACCCT TCGCCAGGAG 
CATGAAGACT CCACACAACG GCTGAAGGGC CTGGAGAAGC AGTACCGCCT GGCACGGCAG 
GAGAAGGAAG AATTGCACAA GCAATTGGTT GAAGCTTCAG AGCGATTGAA ATCCCAGACC 
AAAGAACTCA AAGATGCTCA TCAGCAGCGA AAACGGGCCC TGCAGGAGTT TTCAGAGCTC 
AATGAGCGCA TGGCAGAGCT GAGGTCACAG AAGCAGAAGG TGTCCCGGCA GCTCCGTGAC 
AAGGAGGAGG AGATGGAGGT GGCCATGCAG AAGATTGACT CCATGAGGCA GGATATCCGC 
AAGTCTGAGA AGTCTAGGAA AGAGCTGGAA GCTCGGCTTG AGGACGCAGT CGCTGAGGCC 
TCCAAGGAGA GGAAGCTTCG AGAGCACAGT GAGAGCTTCT CTAAGCAGAT GGAGCGCGAG 
CTCGAGACCC TCAAGGTGAA GCAAGGAGGC CGGGGGCCGG GTGCCACGTT AGAACATCAG 
CAGGAGATCT CCAAAATCAG GTCAGAGCTT GAGAAGAAAG TCTTGTTCTA TGAGGAGGAG 
TTGGTCCGCC GAGAGGCCTC CCATGTGCTA GAAGTAAAGA ATGTGAAGAA GGAGGTGCAC 
GAATCTGAAA GCCACCAGTT GGCCCTGCAG AAAGAGGTCC TGATGCTGAA AGATAAGTTA 
GAAAAGTCAA AACGAGAACG GCACAGTGAG ATGGAGGAGG CCATAGGTGC CATGAAAGAC 
AAGTACGAAC GGGAGAGGGC CATGCTGTTC GACGAGAACA AGAAGTTAAC AGCAGAAAAC 
GAAAAGCTCT GTTCCTTTGT GGATAAACTA ACAGCCCAAA ACAGACAGCT GGAGGACGAG 
CTGCAGGACC TGGCCTCCAA GAAGGAGTCG GTCGCTCACT GGGAGGCGCA GATTGCAGAG 
ATTATTCAGT GGGTCAGCGA TGAGAAAGAT GCCAGAGGCT ACCTTCAAGC ACTTGCTTCT 
AAGATGACCG AAGAGCTTGA GACTTTGAGA AGCTCTAGTT TGGGATCCAG GACACTGGAC 
CCACTCTGGA AGGTCCGTCG GAGCCAGAAG CTGGACATGT CTGCGCGGCT GGAGTTGCAG 
TCCGCTCTCG AGGCAGAGAT CCGTGCCAAG CAGCTGGTTC ACGAGGAGCT GAGGAAGGTC 
AAAGACACCA GCCTAGCCTT CGAAAGCAAA CTGAAGGAGT CAGAAGCCAA AAACAGGGAA 
TTATTAGAAG AAATGCAAAG TCTGAAGAAA AGGATGGAAG AAAAATTTAG AGCAGATACA 
GGGCTCAAAC TTCCAGATTT CCAGGATCCT ATCTTTGAGT ACTTCAACAC TGCTCCTCTT 
GCACATGACC TGACTTTTAG AGACTCGCTC TCCTCCTCAT CTGCATCTTC TCTGCTAGCC 
TTGTGGGAGG ACACTAGCTC AGCTAGTGAT CAGGAAACAC AGGCTTCAAA GTTGGACTTG 
TCCCCATCAG TGTCTGTGGC CACAAGCACA GAACAGCAGG AGGATGCGGC TCGTTCACAG 
CAGAGGCCGT CTACTGTGCC GCTGCCCAAC ACACAGGCCC TCGCCATGGC TGGACCAAAG 
CCCAAGGCAC ACCAGTTCAG CATCAAGTCC TTCCCCAGCC CCACCCAGTG TAGCCACTGT 
ACGTCCTTGA TGGTTGGGCT GATCCGACAG GGCTATGCCT GTGAGGTCTG CGCGTTTTCC 
TGCCATGTGT CCTGCAAAGA CAGCGCTCCC CAGGTGTGCC CCATACCTCC TGAGCAGTCC 
AAGCGGCCTC TCGGCGTAGA CGTGCAGAGG GGCATAGGCA CAGCCTACAA GGGCTACGTC 
AAGGTCCCGA AGCCCACAGG CGTGAAGAAA GGGTGGCAGC GGGCTTACGC AGTGGTCTGT 
GACTGCAAGC TCTTCCTGTA CGACCTGCCA GAAGGGAAGT CCACCCAGCC TGGGGTCATC 
GCCAGTCAAG TCTTAGACCT CAGAGATGAC GAGTTTGCTG TGAGCTCAGT CCTGGCCTCA 
GATGTCATCC ATGCTACACG CCGAGACATC CCGTGTATAT TCAGGGTGAC GGCCTCTCTC 
TTAGGTTCAC CTTCTAAGAC CAGCTCACTG CTCATCCTGA CAGAGAACGA GAATGAAAAG 
AGGAAGTGGG TTGGGATCCT GGAAGGGCTG CAGGCTATCC TCCACAAGAA CCGGCTGAGG 
AGCCAGGTGG TGCACGTGGC ACAGGAAGCG TACGACAGCT CACTGCCGCT CATCAAGACC 
GTCCTGGCTG CCGCTATTGT GGATGGAGAC AGAATTGCGG TCGGCCTGGA AGAAGGGCTC 
TACGTCATTG AGCTCACCCG AGATGTGATC GTCCGCGCTG CTGACTGCAA GAAGGTATAC 
CAGATCGAGC TGGCGCCCAA GGAGAAGCTC ATCCTCCTCC TCTGTGGCCG GAACCACCAC 
GTGCACCTCT ACCCCTGGAC CTCCTTCGAT GGAGCAGAAG CTAGCAACTT TGACATCAAG 
CTCCCAGAAA CGAAGGGCTG CCAGCTCATA GCAACAGGGA CGCTGAGGAA GAGCTCGTCC 
ACCTGCCTGT TTGTCGCCGT GAAGCGGCTG GTCCTTTGCT ACGAGATCCA GAGAACTAAG 
CCTTTCCACC GGAAGTTCAA TGAGATCGTG GCCCCGGGAC ATGTGCAGTG GATGGCCATG 
TTCAAGGACA GGCTCTGTGT TGGCTACCCC TCCGGGTTCT CTCTGTTGAG CATCCAGGGG 
GACGGGCAGC CTCTAGACCT GGTAAATCCC GCTGACCCCT CGCTCGCGTT CCTCTCACAG 
CAGTCTTTCG ATGCCCTCTG TGCTGTAGAG CTCAAAAGTG AGGAGTACCT GCTCTGCTTC 
AGCCACATGG GACTGTACGT GGACCCTCAA GGTCGGAGGT CACGCACGCA GGAGCTCATG 
TGGCCTGCGG CTCCTGTCGC CTGTAGTTGC AGCTCCTCCC ACGTCACGGT GTACAGCGAA 
TACGGGGTGG ATGTCTTCGA CGTGCGCACC ATGGAGTGGG TTCAGACCAT CGGCCTGCGG 
AGGATAAGAC CTCTGAACTC TGATGGTAGC CTCAACCTGC TGGGCTGTGA GCCCCCACGC 
CTCATCTACT TCAAAAACAA GTTCTCAGGC ACCGTCCTCA ATGTGCCCGA TACCTCGGAC 
AACAGCAAGA AGCAGATGCT GCGGACGCGG AGCAAACGGC GCTTCGTCTT CAAGGTTCCA 
GAGGAAGAGA GGCTGCAGCA GCGGCGAGAG ATGCTCAGAG ACCCGGAACT GAGATCCAAA 
ATGATATCCA ATCCGACCAA CTTCAACCAC GTGGCTCACA TGGGCCCTGG CGATGGGATG 
CAGGTGCTCA TGGACCTGCC TCTGAGTGCT GCGCCCACAG CCCAGGAGGA AAAGCAGGGT 
CCTGCCCCAA CAGGCCTCCC TCGGCAGCTC CCATCCAGGA ACAAGCCCTA TGTCTCATGG 
CCGTCCTCAG GTGGGTCTGA GCCTGGAGTG CCTGTGCCTC TGAGGAGCAT GTCTGACCCC 
GACCAGGATT TTGACAAAGA GCCTGACTCT GACTCCACGA AGCACTCGAC TCCGTCCAAC 
AGCTCCAACC CTAGCGGCCC CCCGAGCCCC AACTCACCGC ACCGGAGCCA GCTCCCTCTG 
GAAGGCCTGG ACCAGCCAGC CTGCGACGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling.
Nature communications66449(2015 Mar)
Lant B,Yu B,Goudreault M,Holmyard D,Knight JD,Xu P,Zhao L,Chin K,Wallace E,Zhen M,Gingras AC,Derry WB

Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.
The Journal of biological chemistry289(39)26989-7003(2014 Sep)
Lee IC,Leung T,Tan I

Co-crystal structures of inhibitors with MRCK?, a key regulator of tumor cell invasion.
PloS one6(9)e24825(2011)
Heikkila T,Wheatley E,Crighton D,Schroder E,Boakes A,Kaye SJ,Mezna M,Pang L,Rushbrooke M,Turnbull A,Olson MF

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.
Cell135(1)123-36(2008 Oct)
Tan I,Yong J,Dong JM,Lim L,Leung T

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Cdc42bpb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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