Prrx2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prrx2
Entrez Gene ID	113931
Full Name	paired related homeobox 2
Synonyms	Prx2
General protein information	Preferred Names paired related homeobox 2 Names paired mesoderm homeobox protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3p12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105739.1	NP_001099209.1	paired mesoderm homeobox protein 2

Pathways from BioSystems

Homologies

	PRRX2	XP_001107634.1
Mus musculus (house mouse)	Prrx2	NP_033142.2
Gallus gallus (chicken)	PRRX2	XP_415476.3
Homo sapiens (human)	PRRX2	NP_057391.1
Pan troglodytes (chimpanzee)	PRRX2	XP_520310.2
Rattus norvegicus (Norway rat)	Prrx2	NP_001099209.1
Xenopus tropicalis (tropical clawed frog)	prrx2	XP_002940803.1
Canis lupus familiaris (dog)	PRRX2	XP_548419.3
Bos taurus (cattle)	PRRX2	XP_002691720.3

Gene Ontology
Bibliography

Related articles in PubMed

PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are involved in vasculogenesis during rat embryonic pituitary development.
Higuchi M, Kato T, Yoshida S, Ueharu H, Nishimura N, Kato Y
Cell and tissue research361(2)557-65(2015 Aug)

Expression of Kr?ppel-like factor 6, KLF6, in rat pituitary stem/progenitor cells and its regulation of the PRRX2 gene.
Ueharu H, Higuchi M, Nishimura N, Yoshida S, Shibuya S, Sensui K, Kato T, Kato Y
The Journal of reproduction and development60(4)304-11(2014)

Temporospatial gene expression of Prx1 and Prx2 is involved in morphogenesis of cranial placode-derived tissues through epithelio-mesenchymal interaction during rat embryogenesis.
Higuchi M, Kato T, Chen M, Yako H, Yoshida S, Kanno N, Kato Y
Cell and tissue research353(1)27-40(2013 Jul)

Paired-related homeodomain proteins Prx1 and Prx2 are expressed in embryonic pituitary stem/progenitor cells and may be involved in the early stage of pituitary differentiation.
Susa T, Kato T, Yoshida S, Yako H, Higuchi M, Kato Y
Journal of neuroendocrinology24(9)1201-12(2012 Sep)

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
Wissm?ller S, Kosian T, Wolf M, Finzsch M, Wegner M
Nucleic acids research34(6)1735-44(2006)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are present at the periphery of the embryonic pituitary and participate in pituitary vasculogenesis by differentiation into vascular endothelial cells and pericytes.
Title: PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are involved in vasculogenesis during rat embryonic pituitary development.

expression stimulated by Klf6
Title: Expression of Kr?ppel-like factor 6, KLF6, in rat pituitary stem/progenitor cells and its regulation of the PRRX2 gene.

PRX proteins, especially PRX2, play a role in the morphogenesis of the primordial tissues formed by the epithelio-mesenchymal interaction and that neural crest cells contribute to the morphogenesis of tissues derived from the cranial placode.
Title: Temporospatial gene expression of Prx1 and Prx2 is involved in morphogenesis of cranial placode-derived tissues through epithelio-mesenchymal interaction during rat embryogenesis.

data indicate that PRXs are produced in the pituitary progenitor cells and may play roles in the process of terminal differentiation during early pituitary organogenesis.
Title: Paired-related homeodomain proteins Prx1 and Prx2 are expressed in embryonic pituitary stem/progenitor cells and may be involved in the early stage of pituitary differentiation.

The following Prrx2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prrx2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00034	NM_001105739.1 Latest version!	Rattus norvegicus paired related homeobox 2 (Prrx2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prrx2 ( NM_001105739.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099209.1 Rattus norvegicus paired related homeobox 2 (Prrx2), mRNA.

Price & Availability↑

CloneID	ORa00034
Clone ID Related Accession (Same CDS sequence)	NM_001105739.1
Accession Version	NM_001105739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	paired mesoderm homeobox protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474001.2. On or before Oct 3, 2007 this sequence version replaced XM_001079701.1, XM_238327.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGACAGCG CGGCCGCCGC CTTCGCCTTG GACCCGCCAG CGCCCGGCCC GGGGCCCCCG 
CCCGCACCCG GTGACTGCGC CCAGGCGCGC AAGAACTTCT CGGTGAGCCA CCTCCTGGAC 
CTGGAGGAGG TGGCGGCTGC CGGGCGCAGG GCTGCGGGGC CGGTGCCGGG GCCCGAGGCG 
CGGGAGGGAG CGGCGCGCGA ACCGTCCGGG GGCAGCAGCG GCAGCGAGGC GGCGCCGCAG 
GACGGTGAGT GCGCGGCCCC CGGCCATGGC AGTGCCACCA AACGGAAGAA GAAGCAGCGT 
CGGAATCGAA CCACATTCAA CAGCAGCCAG CTGCAGGCGC TGGAGCGTGT ATTTGAGCGC 
ACACACTACC CTGACGCCTT TGTGCGTGAA GAGCTAGCCC GCCGTGTCAA CCTCAGTGAG 
GCACGTGTCC AAGTCTGGTT CCAGAACCGC CGTGCCAAGT TTCGCCGGAA CGAACGTGCC 
ATGCTGGCTA CCCGCTCTGC CTCGCTGCTC AAGTCTTACG GCCAGGAGGC AGCCATTGAG 
CAGCCTGTGG CCCCCCGACC TACCACACTG AGCCCAGATT ATCTATCCTG GCCAGCATCG 
TCCCCCTACA GCTCGGTGCC TCCCTACAGC CCCGGAGGTT CAAGTCCTGC AACTCCTGGA 
GTCAATATGG CCAACAGCAT CGCTAGCCTT CGCCTCAAGG CCAAAGAGTT CAGCTTACAC 
CACAGCCAGG TGCCCACAGT GAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099209.1
CDS	155..901
Translation	MDSAAAAFALDPPAPGPGPPPAPGDCAQARKNFSVSHLLDLEEVAAAGRRAAGPVPGPEAREGAAREPSGGSSGSEAAPQDGECAAPGHGSATKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTLSPDYLSWPASSPYSSVPPYSPGGSSPATPGVNMANSIASLRLKAKEFSLHHSQVPTVN

Target ORF information:

RefSeq Version	NM_001105739.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus paired related homeobox 2 (Prrx2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105739.1

ORF Insert Sequence:

ATGGACAGCG CGGCCGCCGC CTTCGCCTTG GACCCGCCAG CGCCCGGCCC GGGGCCCCCG 
CCCGCACCCG GTGACTGCGC CCAGGCGCGC AAGAACTTCT CGGTGAGCCA CCTCCTGGAC 
CTGGAGGAGG TGGCGGCTGC CGGGCGCAGG GCTGCGGGGC CGGTGCCGGG GCCCGAGGCG 
CGGGAGGGAG CGGCGCGCGA ACCGTCCGGG GGCAGCAGCG GCAGCGAGGC GGCGCCGCAG 
GACGGTGAGT GCGCGGCCCC CGGCCATGGC AGTGCCACCA AACGGAAGAA GAAGCAGCGT 
CGGAATCGAA CCACATTCAA CAGCAGCCAG CTGCAGGCGC TGGAGCGTGT ATTTGAGCGC 
ACACACTACC CTGACGCCTT TGTGCGTGAA GAGCTAGCCC GCCGTGTCAA CCTCAGTGAG 
GCACGTGTCC AAGTCTGGTT CCAGAACCGC CGTGCCAAGT TTCGCCGGAA CGAACGTGCC 
ATGCTGGCTA CCCGCTCTGC CTCGCTGCTC AAGTCTTACG GCCAGGAGGC AGCCATTGAG 
CAGCCTGTGG CCCCCCGACC TACCACACTG AGCCCAGATT ATCTATCCTG GCCAGCATCG 
TCCCCCTACA GCTCGGTGCC TCCCTACAGC CCCGGAGGTT CAAGTCCTGC AACTCCTGGA 
GTCAATATGG CCAACAGCAT CGCTAGCCTT CGCCTCAAGG CCAAAGAGTT CAGCTTACAC 
CACAGCCAGG TGCCCACAGT GAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are involved in vasculogenesis during rat embryonic pituitary development.
Cell and tissue research361(2)557-65(2015 Aug)
Higuchi M,Kato T,Yoshida S,Ueharu H,Nishimura N,Kato Y

Expression of Kr?ppel-like factor 6, KLF6, in rat pituitary stem/progenitor cells and its regulation of the PRRX2 gene.
The Journal of reproduction and development60(4)304-11(2014)
Ueharu H,Higuchi M,Nishimura N,Yoshida S,Shibuya S,Sensui K,Kato T,Kato Y

Temporospatial gene expression of Prx1 and Prx2 is involved in morphogenesis of cranial placode-derived tissues through epithelio-mesenchymal interaction during rat embryogenesis.
Cell and tissue research353(1)27-40(2013 Jul)
Higuchi M,Kato T,Chen M,Yako H,Yoshida S,Kanno N,Kato Y

Paired-related homeodomain proteins Prx1 and Prx2 are expressed in embryonic pituitary stem/progenitor cells and may be involved in the early stage of pituitary differentiation.
Journal of neuroendocrinology24(9)1201-12(2012 Sep)
Susa T,Kato T,Yoshida S,Yako H,Higuchi M,Kato Y

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
Nucleic acids research34(6)1735-44(2006)
Wissm?ller S,Kosian T,Wolf M,Finzsch M,Wegner M

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Prrx2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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