Grcc10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grcc10
Entrez Gene ID	100362005
Full Name	gene rich cluster, C10 gene
General protein information	Preferred Names gene rich cluster, C10 gene Names protein C10 C10 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42

mRNA and Protein(s)

mRNA	Protein	Name
XM_006237325.3	XP_006237387.1	protein C10 isoform X1
NM_001198725.1	NP_001185654.1	protein C10

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Grcc10	NP_001185654.1
Rattus norvegicus (Norway rat)	LOC100911713	XP_003750707.1

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequencing identifies compound heterozygous mutations in C12orf57 in two siblings with severe intellectual disability, hypoplasia of the corpus callosum, chorioretinal coloboma, and intractable seizures.
Platzer K, H?ning I, Obieglo C, Schwarzmayr T, Gabriel R, Strom TM, Gillessen-Kaesbach G, Kaiser FJ
American journal of medical genetics. Part A164A(8)1976-80(2014 Aug)

A newly recognized autosomal recessive syndrome affecting neurologic function and vision.
Salih MA, Tzschach A, Oystreck DT, Hassan HH, AlDrees A, Elmalik SA, El Khashab HY, Wienker TF, Abu-Amero KK, Bosley TM
American journal of medical genetics. Part A161A(6)1207-13(2013 Jun)

Whole-exome sequencing identifies mutated c12orf57 in recessive corpus callosum hypoplasia.
Akizu N, Shembesh NM, Ben-Omran T, Bastaki L, Al-Tawari A, Zaki MS, Koul R, Spencer E, Rosti RO, Scott E, Nickerson E, Gabriel S, da Gente G, Li J, Deardorff MA, Conlin LK, Horton MA, Zackai EH, Sherr EH, Gleeson JG
American journal of human genetics92(3)392-400(2013 Mar)

Mutations in c12orf57 cause a syndromic form of colobomatous microphthalmia.
Zahrani F, Aldahmesh MA, Alshammari MJ, Al-Hazzaa SA, Alkuraya FS
American journal of human genetics92(3)387-91(2013 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Grcc10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grcc10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08590	NM_001198725.1 Latest version!	Rattus norvegicus gene rich cluster, C10 gene (Grcc10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa27744	XM_006237325.3 Latest version!	Rattus norvegicus gene rich cluster, C10 gene (Grcc10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grcc10 ( NM_001198725.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001185654.1 Rattus norvegicus gene rich cluster, C10 gene (Grcc10), mRNA.

Price & Availability↑

CloneID	ORa08590
Clone ID Related Accession (Same CDS sequence)	NM_001198725.1
Accession Version	NM_001198725.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	protein C10
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM049692.1, FM062242.1 and AC129138.4. On or before Nov 10, 2010 this sequence version replaced XM_002729427.1, XM_002726446.1. ##Evidence-Data-START## Transcript exon combination :: BP475650.1, DV718572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCCG CCTCGGCTCA GCCTGCGGCT CTGAGCGCAG AGCAGGCCAA GGTGGTCTTG 
GCGGAGGTGA TCCAAGCGTT CTCGGCCCCA GAGAACGCCG TGCGTATGGA CGAGGCTAGA 
GACAATGCGT GCAACGATAT GGGCAAGATG CTGCAATTCG TGCTGCCTGT AGCCACACAG 
ATCCAGCAGG AGGTTATTAA AGCCTATGGC TTCAGCTGCG ACGGGGAAGG TGTCCTTAAG 
TTTGCCCGCC TGGTCAAGTC TTACGAAGCC CAGGATCCTG AGATTGCCAG CCTGTCAGGC 
AAGCTAAAGG CCTTGTTCCT GCCACCCATG ACACTACCAC CCCACGGGCC TGCTTCCGGA 
AGCAGTGTGG CTGCCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185654.1
CDS	300..680
Translation	MASASAQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPASGSSVAAS

Target ORF information:

RefSeq Version	NM_001198725.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gene rich cluster, C10 gene (Grcc10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198725.1

ORF Insert Sequence:

ATGGCGTCCG CCTCGGCTCA GCCTGCGGCT CTGAGCGCAG AGCAGGCCAA GGTGGTCTTG 
GCGGAGGTGA TCCAAGCGTT CTCGGCCCCA GAGAACGCCG TGCGTATGGA CGAGGCTAGA 
GACAATGCGT GCAACGATAT GGGCAAGATG CTGCAATTCG TGCTGCCTGT AGCCACACAG 
ATCCAGCAGG AGGTTATTAA AGCCTATGGC TTCAGCTGCG ACGGGGAAGG TGTCCTTAAG 
TTTGCCCGCC TGGTCAAGTC TTACGAAGCC CAGGATCCTG AGATTGCCAG CCTGTCAGGC 
AAGCTAAAGG CCTTGTTCCT GCCACCCATG ACACTACCAC CCCACGGGCC TGCTTCCGGA 
AGCAGTGTGG CTGCCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grcc10 ( XM_006237325.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237387.1 Rattus norvegicus gene rich cluster, C10 gene (Grcc10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa27744
Clone ID Related Accession (Same CDS sequence)	XM_006237325.3
Accession Version	XM_006237325.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein C10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237325.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCCG CCTCGGCTCA GCCTGCGGCT CTGAGCGCAG AGCAGGCCAA GGTGGTCTTG 
GCGGAGGTGA TCCAAGCGTT CTCGGCCCCA GAGAACGCCG TGCGTATGGA CGAGGCTAGA 
GACAATGCGT GCAACGATAT GGGCAAGATG CTGCAATTCG TGCTGCCTGT AGCCACACAG 
ATCCAGCAGG AGGTTATTAA AGCCTATGGC TTCAGCTGCG ACGGGGAAGA TGCTTGCCTG 
ACTACAAGGA GATCTCCTAC TCTCAGGAGC CCCCTTGCCT GCCTCCACAC ACTGGTCTCC 
AGCATTGTGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237387.1
CDS	324..638
Translation	MASASAQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEDACLTTRRSPTLRSPLACLHTLVSSIVR

Target ORF information:

RefSeq Version	XM_006237325.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gene rich cluster, C10 gene (Grcc10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237325.3

ORF Insert Sequence:

ATGGCGTCCG CCTCGGCTCA GCCTGCGGCT CTGAGCGCAG AGCAGGCCAA GGTGGTCTTG 
GCGGAGGTGA TCCAAGCGTT CTCGGCCCCA GAGAACGCCG TGCGTATGGA CGAGGCTAGA 
GACAATGCGT GCAACGATAT GGGCAAGATG CTGCAATTCG TGCTGCCTGT AGCCACACAG 
ATCCAGCAGG AGGTTATTAA AGCCTATGGC TTCAGCTGCG ACGGGGAAGA TGCTTGCCTG 
ACTACAAGGA GATCTCCTAC TCTCAGGAGC CCCCTTGCCT GCCTCCACAC ACTGGTCTCC 
AGCATTGTGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequencing identifies compound heterozygous mutations in C12orf57 in two siblings with severe intellectual disability, hypoplasia of the corpus callosum, chorioretinal coloboma, and intractable seizures.
American journal of medical genetics. Part A164A(8)1976-80(2014 Aug)
Platzer K,H?ning I,Obieglo C,Schwarzmayr T,Gabriel R,Strom TM,Gillessen-Kaesbach G,Kaiser FJ

A newly recognized autosomal recessive syndrome affecting neurologic function and vision.
American journal of medical genetics. Part A161A(6)1207-13(2013 Jun)
Salih MA,Tzschach A,Oystreck DT,Hassan HH,AlDrees A,Elmalik SA,El Khashab HY,Wienker TF,Abu-Amero KK,Bosley TM

Whole-exome sequencing identifies mutated c12orf57 in recessive corpus callosum hypoplasia.
American journal of human genetics92(3)392-400(2013 Mar)
Akizu N,Shembesh NM,Ben-Omran T,Bastaki L,Al-Tawari A,Zaki MS,Koul R,Spencer E,Rosti RO,Scott E,Nickerson E,Gabriel S,da Gente G,Li J,Deardorff MA,Conlin LK,Horton MA,Zackai EH,Sherr EH,Gleeson JG

Mutations in c12orf57 cause a syndromic form of colobomatous microphthalmia.
American journal of human genetics92(3)387-91(2013 Mar)
Zahrani F,Aldahmesh MA,Alshammari MJ,Al-Hazzaa SA,Alkuraya FS

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Grcc10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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