Tas1r2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tas1r2
Entrez Gene ID	100270683
Full Name	taste 1 receptor member 2
Synonyms	Aldh4a1,Gpr71,Tr2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271266.1	NP_001258195.1	taste receptor type 1 member 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TAS1R2	NP_689418.2
	TAS1R2	NP_001121561.1
Bos taurus (cattle)	TAS1R2	NP_001193458.1
Mus musculus (house mouse)	Tas1r2	NP_114079.1
Pan troglodytes (chimpanzee)	LOC100615078	XP_003949358.1
Canis lupus familiaris (dog)	TAS1R2	NP_001026989.1
Rattus norvegicus (Norway rat)	Tas1r2	NP_001258195.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of sweet taste receptor and gut hormone secretion in modelled type 2 diabetes.
Feng R, Qian C, Liu Q, Jin Y, Liu L, Li S, Liao Y, Zhou H, Liu W, Rayner CK, Ma J
General and comparative endocrinology252142-149(2017 Oct)

Expression of synaptogyrin-1 in T1R2-expressing type II taste cells and type III taste cells of rat circumvallate taste buds.
Kotani T, Toyono T, Seta Y, Kitou A, Kataoka S, Toyoshima K
Cell and tissue research353(3)391-8(2013 Sep)

Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.
Wu SV, Chen MC, Rozengurt E
Physiological genomics22(2)139-49(2005 Jul)

Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome research15(1)54-66(2005 Jan)

Human receptors for sweet and umami taste.
Li X, Staszewski L, Xu H, Durick K, Zoller M, Adler E
Proceedings of the National Academy of Sciences of the United States of America99(7)4692-6(2002 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sweet taste molecules of T1R2, T1R3, alpha-gustducin and TRPM5 in ileum were dramatically higher than those in duodenum (P<0.01 for each).
Title: Expression of sweet taste receptor and gut hormone secretion in modelled type 2 diabetes.

A subset of synaptogyrin-1-immunoreactive taste cells also expressed phospholipase Cbeta2, gustducin, or sweet taste receptor (T1R2).
Title: Expression of synaptogyrin-1 in T1R2-expressing type II taste cells and type III taste cells of rat circumvallate taste buds.

The following Tas1r2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tas1r2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12648	NM_001271266.1 Latest version!	Rattus norvegicus taste 1 receptor member 2 (Tas1r2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tas1r2 ( NM_001271266.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258195.1 Rattus norvegicus taste 1 receptor member 2 (Tas1r2), mRNA.

Price & Availability↑

CloneID	ORa12648
Clone ID Related Accession (Same CDS sequence)	NM_001271266.1
Accession Version	NM_001271266.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2532bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	taste receptor type 1 member 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07050241.1. On or before Sep 12, 2012 this sequence version replaced XM_003754109.1, XM_003750067.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF127390.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGTCCCC AGGCAAGGAC ACTCTGCTTG CTGTCTCTCC TGCTGCATGT TCTGCCTAAG 
CCAGGCAAGC TGGTAGAGAA CTCTGACTTC CACCTGGCCG GGGACTACCT CCTGGGTGGC 
CTCTTTACCC TCCATGCCAA CGTGAAGAGC ATCTCCCACC TCAGCTACCT GCAGGTGCCC 
AAGTGCAATG AGTTCACCAT GAAGGTGTTG GGCTACAACC TCATGCAGGC CATGCGTTTC 
GCTGTGGAGG AGATCAACAA CTGTAGCTCC CTGCTACCCG GCGTGCTGCT CGGCTACGAG 
ATGGTGGATG TCTGTTACCT CTCCAACAAT ATCCACCCTG GGCTCTACTT CCTGGCACAG 
GACGACGACC TCCTGCCCAT CCTCAAAGAC TACAGCCAGT ACATGCCCCA CGTGGTGGCT 
GTCATTGGCC CCGACAACTC TGAGTCCGCC ATTACCGTGT CCAACATTCT CTCTCATTTC 
CTCATCCCAC AGATCACATA CAGCGCCATC TCCGACAAGC TGCGGGACAA GCGGCACTTC 
CCTAGCATGC TACGCACAGT GCCCAGCGCC ACCCACCACA TCGAGGCCAT GGTGCAGCTG 
ATGGTTCACT TCCAATGGAA CTGGATTGTG GTGCTGGTGA GCGACGACGA TTACGGCCGC 
GAGAACAGCC ACCTGTTGAG CCAGCGTCTG ACCAAAACGA GCGACATCTG CATTGCCTTC 
CAGGAGGTTC TGCCCATACC TGAGTCCAGC CAGGTCATGA GGTCCGAGGA GCAGAGACAA 
CTGGACAACA TCCTGGACAA GCTGCGGCGG ACCTCGGCGC GCGTCGTGGT GGTGTTCTCG 
CCCGAGCTGA GCCTGTATAG CTTCTTTCAC GAGGTGCTCC GCTGGAACTT CACGGGTTTT 
GTGTGGATCG CCTCTGAGTC CTGGGCTATC GACCCAGTTC TGCATAACCT CACGGAGCTG 
CGCCACACGG GTACTTTTCT GGGCGTCACC ATCCAGAGGG TGTCCATCCC TGGCTTCAGT 
CAGTTCCGAG TGCGCCGTGA CAAGCCAGGG TATCCCGTGC CTAACACGAC CAACCTGCGG 
ACGACCTGCA ACCAGGACTG TGACGCCTGC TTGAACACCA CCAAGTCCTT CAACAACATC 
CTTATACTTT CGGGGGAGCG CGTGGTCTAC AGCGTGTACT CAGCAGTTTA CGCGGTGGCC 
CATGCCCTCC ACAGACTCCT CGGCTGTAAC CGGGTCCGCT GCACCAAGCA AAAGGTCTAC 
CCGTGGCAGC TACTCAGGGA GATCTGGCAC GTCAACTTCA CGCTCCTGGG TAACCGGCTC 
TTCTTTGACC AACAAGGGGA CATGCCGATG CTCTTGGACA TCATCCAGTG GCAGTGGGAC 
CTGAGCCAGA ATCCCTTCCA AAGCATCGCC TCCTATTCTC CCACCAGCAA GAGGCTAACC 
TACATTAACA ATGTGTCCTG GTACACCCCC AACAACACGG TCCCTGTCTC CATGTGTTCC 
AAGAGCTGCC AGCCAGGGCA AATGAAAAAG TCTGTGGGCC TCCACCCTTG TTGCTTCGAG 
TGCTTGGATT GTATGCCAGG CACCTACCTC AACCGCTCAG CAGATGAGTT TAACTGTCTG 
TCCTGCCCGG GTTCCATGTG GTCCTACAAG AACGACATCA CTTGCTTCCA GCGGCGGCCT 
ACCTTCCTGG AGTGGCACGA AGTGCCCACC ATCGTGGTGG CCATACTGGC TGCCCTGGGC 
TTCTTCAGTA CACTGGCCAT TCTTTTCATC TTCTGGAGAC ATTTCCAGAC ACCCATGGTG 
CGCTCGGCCG GTGGCCCCAT GTGCTTCCTG ATGCTCGTGC CCCTGCTGCT GGCGTTTGGG 
ATGGTGCCCG TGTATGTGGG GCCCCCCACG GTCTTCTCAT GCTTCTGCCG ACAGGCTTTC 
TTCACCGTCT GCTTCTCCAT CTGCCTATCC TGCATCACCG TGCGCTCCTT CCAGATCGTG 
TGTGTCTTCA AGATGGCCAG ACGCCTGCCA AGTGCCTACA GTTTTTGGAT GCGTTACCAC 
GGGCCCTATG TCTTCGTGGC CTTCATCACG GCCATCAAGG TGGCCCTGGT GGTGGGCAAC 
ATGCTGGCCA CCACCATCAA CCCCATTGGC CGGACCGACC CGGATGACCC CAACATCATG 
ATCCTCTCGT GCCACCCTAA CTACCGCAAC GGGCTACTGT TCAACACCAG CATGGACTTG 
CTGCTGTCTG TGCTGGGTTT CAGCTTCGCT TACATGGGCA AGGAGCTGCC CACCAACTAC 
AACGAAGCCA AGTTCATCAC TCTCAGCATG ACCTTCTCCT TCACCTCCTC CATCTCCCTC 
TGCACCTTCA TGTCTGTGCA CGACGGCGTG CTGGTCACCA TCATGGACCT CCTGGTCACT 
GTGCTCAACT TCCTGGCCAT CGGCTTGGGA TACTTTGGCC CCAAGTGTTA CATGATCCTT 
TTCTACCCGG AGCGCAACAC CTCAGCCTAT TTCAATAGCA TGATCCAGGG CTACACCATG 
AGGAAGAGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258195.1
CDS	1..2532
Translation	MGPQARTLCLLSLLLHVLPKPGKLVENSDFHLAGDYLLGGLFTLHANVKSISHLSYLQVPKCNEFTMKVLGYNLMQAMRFAVEEINNCSSLLPGVLLGYEMVDVCYLSNNIHPGLYFLAQDDDLLPILKDYSQYMPHVVAVIGPDNSESAITVSNILSHFLIPQITYSAISDKLRDKRHFPSMLRTVPSATHHIEAMVQLMVHFQWNWIVVLVSDDDYGRENSHLLSQRLTKTSDICIAFQEVLPIPESSQVMRSEEQRQLDNILDKLRRTSARVVVVFSPELSLYSFFHEVLRWNFTGFVWIASESWAIDPVLHNLTELRHTGTFLGVTIQRVSIPGFSQFRVRRDKPGYPVPNTTNLRTTCNQDCDACLNTTKSFNNILILSGERVVYSVYSAVYAVAHALHRLLGCNRVRCTKQKVYPWQLLREIWHVNFTLLGNRLFFDQQGDMPMLLDIIQWQWDLSQNPFQSIASYSPTSKRLTYINNVSWYTPNNTVPVSMCSKSCQPGQMKKSVGLHPCCFECLDCMPGTYLNRSADEFNCLSCPGSMWSYKNDITCFQRRPTFLEWHEVPTIVVAILAALGFFSTLAILFIFWRHFQTPMVRSAGGPMCFLMLVPLLLAFGMVPVYVGPPTVFSCFCRQAFFTVCFSICLSCITVRSFQIVCVFKMARRLPSAYSFWMRYHGPYVFVAFITAIKVALVVGNMLATTINPIGRTDPDDPNIMILSCHPNYRNGLLFNTSMDLLLSVLGFSFAYMGKELPTNYNEAKFITLSMTFSFTSSISLCTFMSVHDGVLVTIMDLLVTVLNFLAIGLGYFGPKCYMILFYPERNTSAYFNSMIQGYTMRKS

Target ORF information:

RefSeq Version	NM_001271266.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus taste 1 receptor member 2 (Tas1r2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271266.1

ORF Insert Sequence:

ATGGGTCCCC AGGCAAGGAC ACTCTGCTTG CTGTCTCTCC TGCTGCATGT TCTGCCTAAG 
CCAGGCAAGC TGGTAGAGAA CTCTGACTTC CACCTGGCCG GGGACTACCT CCTGGGTGGC 
CTCTTTACCC TCCATGCCAA CGTGAAGAGC ATCTCCCACC TCAGCTACCT GCAGGTGCCC 
AAGTGCAATG AGTTCACCAT GAAGGTGTTG GGCTACAACC TCATGCAGGC CATGCGTTTC 
GCTGTGGAGG AGATCAACAA CTGTAGCTCC CTGCTACCCG GCGTGCTGCT CGGCTACGAG 
ATGGTGGATG TCTGTTACCT CTCCAACAAT ATCCACCCTG GGCTCTACTT CCTGGCACAG 
GACGACGACC TCCTGCCCAT CCTCAAAGAC TACAGCCAGT ACATGCCCCA CGTGGTGGCT 
GTCATTGGCC CCGACAACTC TGAGTCCGCC ATTACCGTGT CCAACATTCT CTCTCATTTC 
CTCATCCCAC AGATCACATA CAGCGCCATC TCCGACAAGC TGCGGGACAA GCGGCACTTC 
CCTAGCATGC TACGCACAGT GCCCAGCGCC ACCCACCACA TCGAGGCCAT GGTGCAGCTG 
ATGGTTCACT TCCAATGGAA CTGGATTGTG GTGCTGGTGA GCGACGACGA TTACGGCCGC 
GAGAACAGCC ACCTGTTGAG CCAGCGTCTG ACCAAAACGA GCGACATCTG CATTGCCTTC 
CAGGAGGTTC TGCCCATACC TGAGTCCAGC CAGGTCATGA GGTCCGAGGA GCAGAGACAA 
CTGGACAACA TCCTGGACAA GCTGCGGCGG ACCTCGGCGC GCGTCGTGGT GGTGTTCTCG 
CCCGAGCTGA GCCTGTATAG CTTCTTTCAC GAGGTGCTCC GCTGGAACTT CACGGGTTTT 
GTGTGGATCG CCTCTGAGTC CTGGGCTATC GACCCAGTTC TGCATAACCT CACGGAGCTG 
CGCCACACGG GTACTTTTCT GGGCGTCACC ATCCAGAGGG TGTCCATCCC TGGCTTCAGT 
CAGTTCCGAG TGCGCCGTGA CAAGCCAGGG TATCCCGTGC CTAACACGAC CAACCTGCGG 
ACGACCTGCA ACCAGGACTG TGACGCCTGC TTGAACACCA CCAAGTCCTT CAACAACATC 
CTTATACTTT CGGGGGAGCG CGTGGTCTAC AGCGTGTACT CAGCAGTTTA CGCGGTGGCC 
CATGCCCTCC ACAGACTCCT CGGCTGTAAC CGGGTCCGCT GCACCAAGCA AAAGGTCTAC 
CCGTGGCAGC TACTCAGGGA GATCTGGCAC GTCAACTTCA CGCTCCTGGG TAACCGGCTC 
TTCTTTGACC AACAAGGGGA CATGCCGATG CTCTTGGACA TCATCCAGTG GCAGTGGGAC 
CTGAGCCAGA ATCCCTTCCA AAGCATCGCC TCCTATTCTC CCACCAGCAA GAGGCTAACC 
TACATTAACA ATGTGTCCTG GTACACCCCC AACAACACGG TCCCTGTCTC CATGTGTTCC 
AAGAGCTGCC AGCCAGGGCA AATGAAAAAG TCTGTGGGCC TCCACCCTTG TTGCTTCGAG 
TGCTTGGATT GTATGCCAGG CACCTACCTC AACCGCTCAG CAGATGAGTT TAACTGTCTG 
TCCTGCCCGG GTTCCATGTG GTCCTACAAG AACGACATCA CTTGCTTCCA GCGGCGGCCT 
ACCTTCCTGG AGTGGCACGA AGTGCCCACC ATCGTGGTGG CCATACTGGC TGCCCTGGGC 
TTCTTCAGTA CACTGGCCAT TCTTTTCATC TTCTGGAGAC ATTTCCAGAC ACCCATGGTG 
CGCTCGGCCG GTGGCCCCAT GTGCTTCCTG ATGCTCGTGC CCCTGCTGCT GGCGTTTGGG 
ATGGTGCCCG TGTATGTGGG GCCCCCCACG GTCTTCTCAT GCTTCTGCCG ACAGGCTTTC 
TTCACCGTCT GCTTCTCCAT CTGCCTATCC TGCATCACCG TGCGCTCCTT CCAGATCGTG 
TGTGTCTTCA AGATGGCCAG ACGCCTGCCA AGTGCCTACA GTTTTTGGAT GCGTTACCAC 
GGGCCCTATG TCTTCGTGGC CTTCATCACG GCCATCAAGG TGGCCCTGGT GGTGGGCAAC 
ATGCTGGCCA CCACCATCAA CCCCATTGGC CGGACCGACC CGGATGACCC CAACATCATG 
ATCCTCTCGT GCCACCCTAA CTACCGCAAC GGGCTACTGT TCAACACCAG CATGGACTTG 
CTGCTGTCTG TGCTGGGTTT CAGCTTCGCT TACATGGGCA AGGAGCTGCC CACCAACTAC 
AACGAAGCCA AGTTCATCAC TCTCAGCATG ACCTTCTCCT TCACCTCCTC CATCTCCCTC 
TGCACCTTCA TGTCTGTGCA CGACGGCGTG CTGGTCACCA TCATGGACCT CCTGGTCACT 
GTGCTCAACT TCCTGGCCAT CGGCTTGGGA TACTTTGGCC CCAAGTGTTA CATGATCCTT 
TTCTACCCGG AGCGCAACAC CTCAGCCTAT TTCAATAGCA TGATCCAGGG CTACACCATG 
AGGAAGAGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of sweet taste receptor and gut hormone secretion in modelled type 2 diabetes.
General and comparative endocrinology252142-149(2017 Oct)
Feng R,Qian C,Liu Q,Jin Y,Liu L,Li S,Liao Y,Zhou H,Liu W,Rayner CK,Ma J

Expression of synaptogyrin-1 in T1R2-expressing type II taste cells and type III taste cells of rat circumvallate taste buds.
Cell and tissue research353(3)391-8(2013 Sep)
Kotani T,Toyono T,Seta Y,Kitou A,Kataoka S,Toyoshima K

Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.
Physiological genomics22(2)139-49(2005 Jul)
Wu SV,Chen MC,Rozengurt E

Gene and alternative splicing annotation with AIR.
Genome research15(1)54-66(2005 Jan)
Florea L,Di Francesco V,Miller J,Turner R,Yao A,Harris M,Walenz B,Mobarry C,Merkulov GV,Charlab R,Dew I,Deng Z,Istrail S,Li P,Sutton G

Human receptors for sweet and umami taste.
Proceedings of the National Academy of Sciences of the United States of America99(7)4692-6(2002 Apr)
Li X,Staszewski L,Xu H,Durick K,Zoller M,Adler E

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Tas1r2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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