Gene Symbol | APOE |
Entrez Gene ID | 449586 |
Full Name | apolipoprotein E |
Gene Type | protein-coding |
Organism | Pan troglodytes(chimpanzee) |
ORF » Species Summary » Pan troglodytes » APOE cDNA ORF clone
Gene Symbol | APOE |
Entrez Gene ID | 449586 |
Full Name | apolipoprotein E |
Gene Type | protein-coding |
Organism | Pan troglodytes(chimpanzee) |
mRNA | Protein | Name |
---|---|---|
NM_001009007.1 | NP_001009007.1 | apolipoprotein E precursor |
Pan troglodytes (chimpanzee) | APOE | NP_001009007.1 |
APOE | XP_001104482.2 | |
Mus musculus (house mouse) | Apoe | NP_033826.2 |
Canis lupus familiaris (dog) | APOE | XP_866043.1 |
Bos taurus (cattle) | APOE | NP_776416.1 |
Rattus norvegicus (Norway rat) | Apoe | NP_620183.2 |
Xenopus tropicalis (tropical clawed frog) | apoe | XP_004912063.1 |
Homo sapiens (human) | APOE | NP_000032.1 |
The apolipoprotein E (APOE) gene appears functionally monomorphic in chimpanzees (Pan troglodytes).
McIntosh AM, Bennett C, Dickson D, Anestis SF, Watts DP, Webster TH, Fontenot MB, Bradley BJ
PloS one7(10)e47760(2012)
Apolipoprotein E phylogeny and evolution.
Kasap M, Sazci A, Akpinar G, Ergul E
Cell biochemistry and function26(1)43-50(2008 Jan-Feb)
Meat-adaptive genes and the evolution of slower aging in humans.
Finch CE, Stanford CB
The Quarterly review of biology79(1)3-50(2004 Mar)
Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism.
Fullerton SM, Clark AG, Weiss KM, Nickerson DA, Taylor SL, Steng?rd JH, Salomaa V, Vartiainen E, Perola M, Boerwinkle E, Sing CF
American journal of human genetics67(4)881-900(2000 Oct)
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene.
Nickerson DA, Taylor SL, Fullerton SM, Weiss KM, Clark AG, Steng?rd JH, Salomaa V, Boerwinkle E, Sing CF
Genome research10(10)1532-45(2000 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The study found no coding variation within and between chimpanzee populations, suggesting that the maintenance of functionally diverse APOE polymorphisms is a unique feature of human evolution.
Title: The apolipoprotein E (APOE) gene appears functionally monomorphic in chimpanzees (Pan troglodytes).
ApoE evolution and very likely the evolution of other apolipoproteins are influenced by feeding environment and diet of humans, chimpanzees and various other species.
Title: Apolipoprotein E phylogeny and evolution.
The following APOE gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APOE cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OPc00009 | |
Clone ID Related Accession (Same CDS sequence) | NM_001009007.1 | |
Accession Version | NM_001009007.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-15 | |
Organism | Pan troglodytes(chimpanzee) | |
Product | apolipoprotein E precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF261280.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01120800, SAMN01120804 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGGTTC TGTGGGCTGC GTTGCTGGTC ACATTCCTGG CAGGATGCCA GGCCAAGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001009007.1 |
CDS | 59..1012 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001009007.1 |
1 | ATGAAGGTTC TGTGGGCTGC GTTGCTGGTC ACATTCCTGG CAGGATGCCA GGCCAAGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The apolipoprotein E (APOE) gene appears functionally monomorphic in chimpanzees (Pan troglodytes). |
Apolipoprotein E phylogeny and evolution. |
Meat-adaptive genes and the evolution of slower aging in humans. |
Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. |
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene. |