PCSK9 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	PCSK9
Entrez Gene ID	717147
Full Name	proprotein convertase subtilisin/kexin type 9
Synonyms	PC9
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001112660.1	NP_001106130.1	proprotein convertase subtilisin/kexin type 9 precursor
XM_015139580.1	XP_014995066.1	proprotein convertase subtilisin/kexin type 9 isoform X1
XM_015139585.1	XP_014995071.1	proprotein convertase subtilisin/kexin type 9 isoform X2
XM_015139576.1	XP_014995062.1	proprotein convertase subtilisin/kexin type 9 isoform X1
XM_015139585.2	XP_014995071.1	proprotein convertase subtilisin/kexin type 9 isoform X2
XM_015139576.2	XP_014995062.1	proprotein convertase subtilisin/kexin type 9 isoform X1
XM_015139580.2	XP_014995066.1	proprotein convertase subtilisin/kexin type 9 isoform X1

Pathways from BioSystems

Homologies

Saccharomyces cerevisiae (baker's yeast)	YSP3	NP_014645.1
Xenopus tropicalis (tropical clawed frog)	pcsk9	XP_002931479.1
Homo sapiens (human)	PCSK9	NP_777596.2
Danio rerio (zebrafish)	pcsk9	XP_003200725.1
Schizosaccharomyces pombe (fission yeast)	psp3	NP_594848.1
Pan troglodytes (chimpanzee)	PCSK9	NP_001104592.1
	PCSK9	NP_001106130.1
Mus musculus (house mouse)	Pcsk9	NP_705793.1
Rattus norvegicus (Norway rat)	Pcsk9	NP_954862.2
Gallus gallus (chicken)	PCSK9	XP_003641739.2

Gene Ontology
Bibliography

Related articles in PubMed

Evidence for positive selection in the C-terminal domain of the cholesterol metabolism gene PCSK9 based on phylogenetic analysis in 14 primate species.
Ding K, McDonough SJ, Kullo IJ
PloS one2(10)e1098(2007 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PCSK9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCSK9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMb04670	NM_001112660.1 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00
OMb25336	XM_015139576.1 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00
OMb25336	XM_015139580.1 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00
OMb25337	XM_015139585.1 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00
OMb58524	XM_015139576.2 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMb58524	XM_015139580.2 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMb58525	XM_015139585.2 Latest version!	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PCSK9 ( NM_001112660.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001106130.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), mRNA.

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CloneID	OMb04670
Clone ID Related Accession (Same CDS sequence)	NM_001112660.1
Accession Version	NM_001112660.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2079bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF692502.1. On or before Dec 19, 2007 this sequence version replaced XR_013551.1, XM_001093974.1. ##Evidence-Data-START## Transcript exon combination :: EF692502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688453, SAMEA4688465 [ECO:0000348] ##Evidence-Data-END##

ATGGGTACCG TCAGCTCCAG GCGGTCCTGG TGGCCTCTGC CGCTGCCACT GCTGCTGCTC 
CTGCTCCTGG GTCCCGCTGG CGCCCGTGCG CAGGAGGACG AGGACGGCGA CTACGAGGAG 
CTGGTGCTAG CCTTGCGTTC CGAGGAGGAC GGCCTGGCCG ACGCACCCGA GCACGGAGCC 
ACAGCCACCT TCCACCGCTG CGCCAAGGAT CCGTGGAGGC TGCCCGGCAC CTACGTGGTG 
GTGCTGAAGG AGGAGACCCA CCGCTCGCAG TCAGAGCGCA CTGCCCGCCG CCTGCAGGCC 
CAAGCTGCCC GCCGGGGATA CCTCACCAAG ATCCTGCATG TCTTCCATCA CCTTCTTCCT 
GGCTTCCTGG TGAAGATGAG TGGCGACCTG CTGGAGCTGG CCCTGAAGTT GCCCCATGTC 
GACTACATCG AGGAGGACTC CTCTGTCTTT GCCCAGAGCA TCCCATGGAA CCTGGAGCGA 
ATTACTCCTG CACGGTACCG GGCGGATGAA TACCAGCCCC CCAAAGGAGG CAGCCTGGTG 
GAGGTGTATC TCCTAGACAC CAGCATACAG AGTGACCACC GGGAAATCGA GGGCAGGGTC 
ATGGTCACCG ACTTCGAGAG TGTGCCCGAG GAGGACGGGA CCCGCTTCCA CAGACAGGCC 
AGCAAGTGTG ACAGCCATGG CACCCACCTG GCAGGGGTGG TCAGCGGCCG GGATGCCGGC 
GTGGCCAAGG GTGCCGGCCT GCGTAGCCTG CGCGTGCTCA ACTGCCAAGG GAAGGGCACG 
GTCAGCGGCA CCCTCATAGG TCTGGAGTTT ATTCGGAAAA GCCAGCTGGT CCAGCCCGTG 
GGGCCACTGG TTGTGCTGCT GCCCCTGGCG GGTGGGTACA GCCGGGTCTT CAACGCCGCC 
TGCCAGCGCC TGGCGAGGGC TGGGGTCGTG CTGGTCACCG CTGCCGGCAA CTTCCGGGAC 
GATGCCTGCC TCTACTCCCC AGCCTCGGCT CCCGAGGTCA TCACAGTTGG GGCCACCAAT 
GCCCAGGACC AGCCGGTGAC CCTGGGGACT TTGGGGACCA ACTTTGGCCG CTGTGTGGAC 
CTCTTTGCCC CAGGGGAGGA CATCATTGGT GCCTCCAGCG ACTGCAGCAC CTGCTTTGTG 
TCACGGAGTG GGACATCGCA GGCTGCTGCC CACGTGGCTG GCATTGCAGC CATGATGCTG 
TCTGCCGAGC CGGAGCTCAC TCTGGCCGAG TTGAGGCAGA GACTGATCCA CTTCTCTGCC 
AAAGATGTCA TCAATGAGGC CTGGTTCCCT GAGGACCAGC GGGTACTGAC CCCCAACCTG 
GTGGCCGCCC TGCCCCCCAG CACCCACAGG GCAGGTTGGC AGCTGTTTTG CAGGACTGTG 
TGGTCAGCAC ACTCGGGGCC TACACGGATG GCCACAGCCG TAGCCCGCTG CGCCCAGGAT 
GAGGAGCTGC TGAGCTGCTC CAGTTTCTCC AGGAGTGGGA AGCGGCGGGG CGAGCGCATC 
GAGGCCCAAG GGGGCAAGCG GGTCTGCCGG GCCCACAACG CTTTTGGGGG TGAGGGTGTC 
TACGCCATTG CCAGGTGCTG CCTGCTACCC CAGGTCAACT GCAGCGTCCA CACAGCTCCA 
CCAGCTGGGG CCAGCATGGG GACCCGTGTC CACTGCCATC AGCAGGGCCA CGTCCTCACA 
GGCTGCAGCT CCCACTGGGA GGTGGAGGAC CTTGGCACCC ACAAGCCGCC TGTGCTGAGG 
CCACGAGGTC AGCCCAACCA GTGTGTGGGC CACAGGGAGG CCAGCATCCA CGCTTCCTGC 
TGCCATGCCC CAGGTCTGGA ATGCAAAGTC AAGGAGCATG GAATCCCGGC CCCTCAGGAG 
CAGGTTATCG TGGCCTGTGA GGACGGCTGG ACCCTGACCG GCTGCAGTCC CCTCCCTGGG 
ACCTCCCATG TCCTGGGGGC CTACGCTGTA GACAACACGT GTGTGGTCAG GAGCCGGGAC 
GTCAGCACCA CAGGCAGCAC CAGCAAAGAA GCCGTGGCAG CCGTTGCCAT CTGCTGCCGG 
AGCCGGCACC TGGTGCAGGC CTCCCAAGAG CTCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106130.1
CDS	1..2079
Translation	MGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	NM_001112660.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001112660.1

ORF Insert Sequence:

ATGGGTACCG TCAGCTCCAG GCGGTCCTGG TGGCCTCTGC CGCTGCCACT GCTGCTGCTC 
CTGCTCCTGG GTCCCGCTGG CGCCCGTGCG CAGGAGGACG AGGACGGCGA CTACGAGGAG 
CTGGTGCTAG CCTTGCGTTC CGAGGAGGAC GGCCTGGCCG ACGCACCCGA GCACGGAGCC 
ACAGCCACCT TCCACCGCTG CGCCAAGGAT CCGTGGAGGC TGCCCGGCAC CTACGTGGTG 
GTGCTGAAGG AGGAGACCCA CCGCTCGCAG TCAGAGCGCA CTGCCCGCCG CCTGCAGGCC 
CAAGCTGCCC GCCGGGGATA CCTCACCAAG ATCCTGCATG TCTTCCATCA CCTTCTTCCT 
GGCTTCCTGG TGAAGATGAG TGGCGACCTG CTGGAGCTGG CCCTGAAGTT GCCCCATGTC 
GACTACATCG AGGAGGACTC CTCTGTCTTT GCCCAGAGCA TCCCATGGAA CCTGGAGCGA 
ATTACTCCTG CACGGTACCG GGCGGATGAA TACCAGCCCC CCAAAGGAGG CAGCCTGGTG 
GAGGTGTATC TCCTAGACAC CAGCATACAG AGTGACCACC GGGAAATCGA GGGCAGGGTC 
ATGGTCACCG ACTTCGAGAG TGTGCCCGAG GAGGACGGGA CCCGCTTCCA CAGACAGGCC 
AGCAAGTGTG ACAGCCATGG CACCCACCTG GCAGGGGTGG TCAGCGGCCG GGATGCCGGC 
GTGGCCAAGG GTGCCGGCCT GCGTAGCCTG CGCGTGCTCA ACTGCCAAGG GAAGGGCACG 
GTCAGCGGCA CCCTCATAGG TCTGGAGTTT ATTCGGAAAA GCCAGCTGGT CCAGCCCGTG 
GGGCCACTGG TTGTGCTGCT GCCCCTGGCG GGTGGGTACA GCCGGGTCTT CAACGCCGCC 
TGCCAGCGCC TGGCGAGGGC TGGGGTCGTG CTGGTCACCG CTGCCGGCAA CTTCCGGGAC 
GATGCCTGCC TCTACTCCCC AGCCTCGGCT CCCGAGGTCA TCACAGTTGG GGCCACCAAT 
GCCCAGGACC AGCCGGTGAC CCTGGGGACT TTGGGGACCA ACTTTGGCCG CTGTGTGGAC 
CTCTTTGCCC CAGGGGAGGA CATCATTGGT GCCTCCAGCG ACTGCAGCAC CTGCTTTGTG 
TCACGGAGTG GGACATCGCA GGCTGCTGCC CACGTGGCTG GCATTGCAGC CATGATGCTG 
TCTGCCGAGC CGGAGCTCAC TCTGGCCGAG TTGAGGCAGA GACTGATCCA CTTCTCTGCC 
AAAGATGTCA TCAATGAGGC CTGGTTCCCT GAGGACCAGC GGGTACTGAC CCCCAACCTG 
GTGGCCGCCC TGCCCCCCAG CACCCACAGG GCAGGTTGGC AGCTGTTTTG CAGGACTGTG 
TGGTCAGCAC ACTCGGGGCC TACACGGATG GCCACAGCCG TAGCCCGCTG CGCCCAGGAT 
GAGGAGCTGC TGAGCTGCTC CAGTTTCTCC AGGAGTGGGA AGCGGCGGGG CGAGCGCATC 
GAGGCCCAAG GGGGCAAGCG GGTCTGCCGG GCCCACAACG CTTTTGGGGG TGAGGGTGTC 
TACGCCATTG CCAGGTGCTG CCTGCTACCC CAGGTCAACT GCAGCGTCCA CACAGCTCCA 
CCAGCTGGGG CCAGCATGGG GACCCGTGTC CACTGCCATC AGCAGGGCCA CGTCCTCACA 
GGCTGCAGCT CCCACTGGGA GGTGGAGGAC CTTGGCACCC ACAAGCCGCC TGTGCTGAGG 
CCACGAGGTC AGCCCAACCA GTGTGTGGGC CACAGGGAGG CCAGCATCCA CGCTTCCTGC 
TGCCATGCCC CAGGTCTGGA ATGCAAAGTC AAGGAGCATG GAATCCCGGC CCCTCAGGAG 
CAGGTTATCG TGGCCTGTGA GGACGGCTGG ACCCTGACCG GCTGCAGTCC CCTCCCTGGG 
ACCTCCCATG TCCTGGGGGC CTACGCTGTA GACAACACGT GTGTGGTCAG GAGCCGGGAC 
GTCAGCACCA CAGGCAGCAC CAGCAAAGAA GCCGTGGCAG CCGTTGCCAT CTGCTGCCGG 
AGCCGGCACC TGGTGCAGGC CTCCCAAGAG CTCCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCSK9 ( XM_015139580.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014995066.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMb25336
Clone ID Related Accession (Same CDS sequence)	XM_015139580.1 , XM_015139576.1
Accession Version	XM_015139580.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAGGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014995066.1
CDS	580..3015
Translation	MGLWWRDLRAPGVKHPHPRRFPQRRRGARGCRRAPPLSSGSEPGGVSQAVRLSQAGRDVSLQRRLPAPSQDSARPFARPEPELQLLHSPPHRKAQGAARVDRARPLGLLIRTATSPLALMGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	XM_015139580.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015139580.1

ORF Insert Sequence:

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAGGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCSK9 ( XM_015139576.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014995062.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb25336
Clone ID Related Accession (Same CDS sequence)	XM_015139580.1 , XM_015139576.1
Accession Version	XM_015139576.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAGGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014995062.1
CDS	580..3015
Translation	MGLWWRDLRAPGVKHPHPRRFPQRRRGARGCRRAPPLSSGSEPGGVSQAVRLSQAGRDVSLQRRLPAPSQDSARPFARPEPELQLLHSPPHRKAQGAARVDRARPLGLLIRTATSPLALMGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	XM_015139576.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015139576.1

ORF Insert Sequence:

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAGGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCSK9 ( XM_015139585.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014995071.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMb25337
Clone ID Related Accession (Same CDS sequence)	XM_015139585.1
Accession Version	XM_015139585.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA GAGGCAGCCT GGTGGAGGTG 
TATCTCCTAG ACACCAGCAT ACAGAGTGAC CACCGGGAAA TCGAGGGCAG GGTCATGGTC 
ACCGACTTCG AGAGTGTGCC CGAGGAGGAC GGGACCCGCT TCCACAGACA GGCCAGCAAG 
TGTGACAGCC ATGGCACCCA CCTGGCAGGG GTGGTCAGCG GCCGGGATGC CGGCGTGGCC 
AAGGGTGCCG GCCTGCGTAG CCTGCGCGTG CTCAACTGCC AAGGGAAGGG CACGGTCAGC 
GGCACCCTCA TAGGTCTGGA GTTTATTCGG AAAAGCCAGC TGGTCCAGCC CGTGGGGCCA 
CTGGTTGTGC TGCTGCCCCT GGCGGGTGGG TACAGCCGGG TCTTCAACGC CGCCTGCCAG 
CGCCTGGCGA GGGCTGGGGT CGTGCTGGTC ACCGCTGCCG GCAACTTCCG GGACGATGCC 
TGCCTCTACT CTCCAGCCTC GGCTCCCGAG GTCATCACAG TTGGGGCCAC CAATGCCCAG 
GACCAGCCGG TGACCCTGGG GACTTTGGGG ACCAACTTTG GCCGCTGTGT GGACCTCTTT 
GCCCCAGGGG AGGACATCAT TGGTGCCTCC AGCGACTGCA GCACCTGCTT TGTGTCACGG 
AGTGGGACAT CGCAGGCTGC TGCCCACGTG GCTGGCATTG CAGCCATGAT GCTGTCTGCC 
GAGCCGGAGC TCACTCTGGC CGAGTTGAGG CAGAGACTGA TCCACTTCTC TGCCAAAGAT 
GTCATCAATG AGGCCTGGTT CCCTGAGGAC CAGCGGGTAC TGACCCCCAA CCTGGTGGCC 
GCCCTGCCCC CCAGCACCCA CAGGGCAGGT TGGCAGCTGT TTTGCAGGAC TGTGTGGTCA 
GCACACTCGG GGCCTACACG GATGGCCACA GCCGTAGCCC GCTGCGCCCA GGATGAGGAG 
CTGCTGAGCT GCTCCAGTTT CTCCAGGAGT GGGAAGCGGC GGGGCGAGCG CATCGAGGCC 
CAAGGGGGCA AGCGGGTCTG CCGGGCCCAC AACGCTTTTG GGGGTGAGGG TGTCTACGCC 
ATTGCCAGGT GCTGCCTGCT ACCCCAGGTC AACTGCAGCG TCCACACAGC TCCACCAGCT 
GGGGCCAGCA TGGGGACCCG TGTCCACTGC CATCAGCAGG GCCACGTCCT CACAGGCTGC 
AGCTCCCACT GGGAGGTGGA GGACCTTGGC ACCCACAAGC CGCCTGTGCT GAGGCCACGA 
GGTCAGCCCA ACCAGTGTGT GGGCCACAGG GAGGCCAGCA TCCACGCTTC CTGCTGCCAT 
GCCCCAGGTC TGGAATGCAA AGTCAAGGAG CATGGAATCC CGGCCCCTCA GGAGCAGGTT 
ATCGTGGCCT GTGAGGACGG CTGGACCCTG ACCGGCTGCA GTCCCCTCCC TGGGACCTCC 
CATGTCCTGG GGGCCTACGC TGTAGACAAC ACGTGTGTGG TCAGGAGCCG GGACGTCAGC 
ACCACAGGCA GCACCAGCAA AGAAGCCGTG GCAGCCGTTG CCATCTGCTG CCGGAGCCGG 
CACCTGGTGC AGGCCTCCCA GGAGCTCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014995071.1
CDS	580..3012
Translation	MGLWWRDLRAPGVKHPHPRRFPQRRRGARGCRRAPPLSSGSEPGGVSQAVRLSQAGRDVSLQRRLPAPSQDSARPFARPEPELQLLHSPPHRKAQGAARVDRARPLGLLIRTATSPLALMGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPRGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	XM_015139585.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015139585.1

ORF Insert Sequence:

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA GAGGCAGCCT GGTGGAGGTG 
TATCTCCTAG ACACCAGCAT ACAGAGTGAC CACCGGGAAA TCGAGGGCAG GGTCATGGTC 
ACCGACTTCG AGAGTGTGCC CGAGGAGGAC GGGACCCGCT TCCACAGACA GGCCAGCAAG 
TGTGACAGCC ATGGCACCCA CCTGGCAGGG GTGGTCAGCG GCCGGGATGC CGGCGTGGCC 
AAGGGTGCCG GCCTGCGTAG CCTGCGCGTG CTCAACTGCC AAGGGAAGGG CACGGTCAGC 
GGCACCCTCA TAGGTCTGGA GTTTATTCGG AAAAGCCAGC TGGTCCAGCC CGTGGGGCCA 
CTGGTTGTGC TGCTGCCCCT GGCGGGTGGG TACAGCCGGG TCTTCAACGC CGCCTGCCAG 
CGCCTGGCGA GGGCTGGGGT CGTGCTGGTC ACCGCTGCCG GCAACTTCCG GGACGATGCC 
TGCCTCTACT CTCCAGCCTC GGCTCCCGAG GTCATCACAG TTGGGGCCAC CAATGCCCAG 
GACCAGCCGG TGACCCTGGG GACTTTGGGG ACCAACTTTG GCCGCTGTGT GGACCTCTTT 
GCCCCAGGGG AGGACATCAT TGGTGCCTCC AGCGACTGCA GCACCTGCTT TGTGTCACGG 
AGTGGGACAT CGCAGGCTGC TGCCCACGTG GCTGGCATTG CAGCCATGAT GCTGTCTGCC 
GAGCCGGAGC TCACTCTGGC CGAGTTGAGG CAGAGACTGA TCCACTTCTC TGCCAAAGAT 
GTCATCAATG AGGCCTGGTT CCCTGAGGAC CAGCGGGTAC TGACCCCCAA CCTGGTGGCC 
GCCCTGCCCC CCAGCACCCA CAGGGCAGGT TGGCAGCTGT TTTGCAGGAC TGTGTGGTCA 
GCACACTCGG GGCCTACACG GATGGCCACA GCCGTAGCCC GCTGCGCCCA GGATGAGGAG 
CTGCTGAGCT GCTCCAGTTT CTCCAGGAGT GGGAAGCGGC GGGGCGAGCG CATCGAGGCC 
CAAGGGGGCA AGCGGGTCTG CCGGGCCCAC AACGCTTTTG GGGGTGAGGG TGTCTACGCC 
ATTGCCAGGT GCTGCCTGCT ACCCCAGGTC AACTGCAGCG TCCACACAGC TCCACCAGCT 
GGGGCCAGCA TGGGGACCCG TGTCCACTGC CATCAGCAGG GCCACGTCCT CACAGGCTGC 
AGCTCCCACT GGGAGGTGGA GGACCTTGGC ACCCACAAGC CGCCTGTGCT GAGGCCACGA 
GGTCAGCCCA ACCAGTGTGT GGGCCACAGG GAGGCCAGCA TCCACGCTTC CTGCTGCCAT 
GCCCCAGGTC TGGAATGCAA AGTCAAGGAG CATGGAATCC CGGCCCCTCA GGAGCAGGTT 
ATCGTGGCCT GTGAGGACGG CTGGACCCTG ACCGGCTGCA GTCCCCTCCC TGGGACCTCC 
CATGTCCTGG GGGCCTACGC TGTAGACAAC ACGTGTGTGG TCAGGAGCCG GGACGTCAGC 
ACCACAGGCA GCACCAGCAA AGAAGCCGTG GCAGCCGTTG CCATCTGCTG CCGGAGCCGG 
CACCTGGTGC AGGCCTCCCA GGAGCTCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCSK9 ( XM_015139576.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014995062.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb58524
Clone ID Related Accession (Same CDS sequence)	XM_015139576.2 , XM_015139580.2
Accession Version	XM_015139576.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041754.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139576.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAAGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014995062.1
CDS	84..2519
Translation	MGLWWRDLRAPGVKHPHPRRFPQRRRGARGCRRAPPLSSGSEPGGVSQAVRLSQAGRDVSLQRRLPAPSQDSARPFARPEPELQLLHSPPHRKAQGAARVDRARPLGLLIRTATSPLALMGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	XM_015139576.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015139576.2

ORF Insert Sequence:

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAAGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCSK9 ( XM_015139580.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014995066.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X2, mRNA.

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CloneID	OMb58524
Clone ID Related Accession (Same CDS sequence)	XM_015139576.2 , XM_015139580.2
Accession Version	XM_015139580.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041754.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139580.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAAGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014995066.1
CDS	84..2519
Translation	MGLWWRDLRAPGVKHPHPRRFPQRRRGARGCRRAPPLSSGSEPGGVSQAVRLSQAGRDVSLQRRLPAPSQDSARPFARPEPELQLLHSPPHRKAQGAARVDRARPLGLLIRTATSPLALMGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	XM_015139580.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015139580.2

ORF Insert Sequence:

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA AAGGAGGCAG CCTGGTGGAG 
GTGTATCTCC TAGACACCAG CATACAGAGT GACCACCGGG AAATCGAGGG CAGGGTCATG 
GTCACCGACT TCGAGAGTGT GCCCGAGGAG GACGGGACCC GCTTCCACAG ACAGGCCAGC 
AAGTGTGACA GCCATGGCAC CCACCTGGCA GGGGTGGTCA GCGGCCGGGA TGCCGGCGTG 
GCCAAGGGTG CCGGCCTGCG TAGCCTGCGC GTGCTCAACT GCCAAGGGAA GGGCACGGTC 
AGCGGCACCC TCATAGGTCT GGAGTTTATT CGGAAAAGCC AGCTGGTCCA GCCCGTGGGG 
CCACTGGTTG TGCTGCTGCC CCTGGCGGGT GGGTACAGCC GGGTCTTCAA CGCCGCCTGC 
CAGCGCCTGG CGAGGGCTGG GGTCGTGCTG GTCACCGCTG CCGGCAACTT CCGGGACGAT 
GCCTGCCTCT ACTCTCCAGC CTCGGCTCCC GAGGTCATCA CAGTTGGGGC CACCAATGCC 
CAGGACCAGC CGGTGACCCT GGGGACTTTG GGGACCAACT TTGGCCGCTG TGTGGACCTC 
TTTGCCCCAG GGGAGGACAT CATTGGTGCC TCCAGCGACT GCAGCACCTG CTTTGTGTCA 
CGGAGTGGGA CATCGCAGGC TGCTGCCCAC GTGGCTGGCA TTGCAGCCAT GATGCTGTCT 
GCCGAGCCGG AGCTCACTCT GGCCGAGTTG AGGCAGAGAC TGATCCACTT CTCTGCCAAA 
GATGTCATCA ATGAGGCCTG GTTCCCTGAG GACCAGCGGG TACTGACCCC CAACCTGGTG 
GCCGCCCTGC CCCCCAGCAC CCACAGGGCA GGTTGGCAGC TGTTTTGCAG GACTGTGTGG 
TCAGCACACT CGGGGCCTAC ACGGATGGCC ACAGCCGTAG CCCGCTGCGC CCAGGATGAG 
GAGCTGCTGA GCTGCTCCAG TTTCTCCAGG AGTGGGAAGC GGCGGGGCGA GCGCATCGAG 
GCCCAAGGGG GCAAGCGGGT CTGCCGGGCC CACAACGCTT TTGGGGGTGA GGGTGTCTAC 
GCCATTGCCA GGTGCTGCCT GCTACCCCAG GTCAACTGCA GCGTCCACAC AGCTCCACCA 
GCTGGGGCCA GCATGGGGAC CCGTGTCCAC TGCCATCAGC AGGGCCACGT CCTCACAGGC 
TGCAGCTCCC ACTGGGAGGT GGAGGACCTT GGCACCCACA AGCCGCCTGT GCTGAGGCCA 
CGAGGTCAGC CCAACCAGTG TGTGGGCCAC AGGGAGGCCA GCATCCACGC TTCCTGCTGC 
CATGCCCCAG GTCTGGAATG CAAAGTCAAG GAGCATGGAA TCCCGGCCCC TCAGGAGCAG 
GTTATCGTGG CCTGTGAGGA CGGCTGGACC CTGACCGGCT GCAGTCCCCT CCCTGGGACC 
TCCCATGTCC TGGGGGCCTA CGCTGTAGAC AACACGTGTG TGGTCAGGAG CCGGGACGTC 
AGCACCACAG GCAGCACCAG CAAAGAAGCC GTGGCAGCCG TTGCCATCTG CTGCCGGAGC 
CGGCACCTGG TGCAGGCCTC CCAAGAGCTC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCSK9 ( XM_015139585.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014995071.1 Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMb58525
Clone ID Related Accession (Same CDS sequence)	XM_015139585.2
Accession Version	XM_015139585.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	proprotein convertase subtilisin/kexin type 9 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041754.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139585.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA GAGGCAGCCT GGTGGAGGTG 
TATCTCCTAG ACACCAGCAT ACAGAGTGAC CACCGGGAAA TCGAGGGCAG GGTCATGGTC 
ACCGACTTCG AGAGTGTGCC CGAGGAGGAC GGGACCCGCT TCCACAGACA GGCCAGCAAG 
TGTGACAGCC ATGGCACCCA CCTGGCAGGG GTGGTCAGCG GCCGGGATGC CGGCGTGGCC 
AAGGGTGCCG GCCTGCGTAG CCTGCGCGTG CTCAACTGCC AAGGGAAGGG CACGGTCAGC 
GGCACCCTCA TAGGTCTGGA GTTTATTCGG AAAAGCCAGC TGGTCCAGCC CGTGGGGCCA 
CTGGTTGTGC TGCTGCCCCT GGCGGGTGGG TACAGCCGGG TCTTCAACGC CGCCTGCCAG 
CGCCTGGCGA GGGCTGGGGT CGTGCTGGTC ACCGCTGCCG GCAACTTCCG GGACGATGCC 
TGCCTCTACT CTCCAGCCTC GGCTCCCGAG GTCATCACAG TTGGGGCCAC CAATGCCCAG 
GACCAGCCGG TGACCCTGGG GACTTTGGGG ACCAACTTTG GCCGCTGTGT GGACCTCTTT 
GCCCCAGGGG AGGACATCAT TGGTGCCTCC AGCGACTGCA GCACCTGCTT TGTGTCACGG 
AGTGGGACAT CGCAGGCTGC TGCCCACGTG GCTGGCATTG CAGCCATGAT GCTGTCTGCC 
GAGCCGGAGC TCACTCTGGC CGAGTTGAGG CAGAGACTGA TCCACTTCTC TGCCAAAGAT 
GTCATCAATG AGGCCTGGTT CCCTGAGGAC CAGCGGGTAC TGACCCCCAA CCTGGTGGCC 
GCCCTGCCCC CCAGCACCCA CAGGGCAGGT TGGCAGCTGT TTTGCAGGAC TGTGTGGTCA 
GCACACTCGG GGCCTACACG GATGGCCACA GCCGTAGCCC GCTGCGCCCA GGATGAGGAG 
CTGCTGAGCT GCTCCAGTTT CTCCAGGAGT GGGAAGCGGC GGGGCGAGCG CATCGAGGCC 
CAAGGGGGCA AGCGGGTCTG CCGGGCCCAC AACGCTTTTG GGGGTGAGGG TGTCTACGCC 
ATTGCCAGGT GCTGCCTGCT ACCCCAGGTC AACTGCAGCG TCCACACAGC TCCACCAGCT 
GGGGCCAGCA TGGGGACCCG TGTCCACTGC CATCAGCAGG GCCACGTCCT CACAGGCTGC 
AGCTCCCACT GGGAGGTGGA GGACCTTGGC ACCCACAAGC CGCCTGTGCT GAGGCCACGA 
GGTCAGCCCA ACCAGTGTGT GGGCCACAGG GAGGCCAGCA TCCACGCTTC CTGCTGCCAT 
GCCCCAGGTC TGGAATGCAA AGTCAAGGAG CATGGAATCC CGGCCCCTCA GGAGCAGGTT 
ATCGTGGCCT GTGAGGACGG CTGGACCCTG ACCGGCTGCA GTCCCCTCCC TGGGACCTCC 
CATGTCCTGG GGGCCTACGC TGTAGACAAC ACGTGTGTGG TCAGGAGCCG GGACGTCAGC 
ACCACAGGCA GCACCAGCAA AGAAGCCGTG GCAGCCGTTG CCATCTGCTG CCGGAGCCGG 
CACCTGGTGC AGGCCTCCCA AGAGCTCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014995071.1
CDS	84..2516
Translation	MGLWWRDLRAPGVKHPHPRRFPQRRRGARGCRRAPPLSSGSEPGGVSQAVRLSQAGRDVSLQRRLPAPSQDSARPFARPEPELQLLHSPPHRKAQGAARVDRARPLGLLIRTATSPLALMGTVSSRRSWWPLPLPLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPRGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVARCAQDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCSPLPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSKEAVAAVAICCRSRHLVQASQELQ

Target ORF information:

RefSeq Version	XM_015139585.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015139585.2

ORF Insert Sequence:

ATGGGGCTCT GGTGGCGTGA TCTGCGGGCC CCAGGCGTCA AGCACCCACA CCCTAGAAGG 
TTTCCGCAGC GGCGTCGAGG CGCTCGTGGT TGCAGGAGGG CGCCGCCGCT CAGTTCAGGG 
TCCGAGCCTG GAGGAGTGAG CCAGGCAGTG AGACTGTCTC AGGCGGGCCG GGACGTGTCG 
TTGCAGCGGC GGCTCCCAGC TCCCAGCCAG GATTCCGCGC GCCCCTTCGC GCGCCCTGAG 
CCTGAACTCC AGCTCCTGCA CAGTCCTCCC CACCGTAAGG CTCAAGGCGC CGCCCGCGTG 
GACCGTGCAC GGCCTCTAGG TCTCCTCATC AGGACGGCAA CCTCTCCCCT GGCCCTGATG 
GGTACCGTCA GCTCCAGGCG GTCCTGGTGG CCTCTGCCGC TGCCACTGCT GCTGCTCCTG 
CTCCTGGGTC CCGCTGGCGC CCGTGCGCAG GAGGACGAGG ACGGCGACTA CGAGGAGCTG 
GTGCTAGCGT TGCGTTCCGA GGAGGACGGC CTGGCCGACG CACCCGAGCA CGGAGCCACA 
GCCACCTTCC ACCGCTGCGC CAAGGATCCG TGGAGGCTGC CCGGCACCTA CGTGGTGGTG 
CTGAAGGAGG AGACCCACCG CTCGCAGTCA GAGCGCACTG CCCGCCGCCT GCAGGCCCAA 
GCTGCCCGCC GGGGATACCT CACCAAGATC CTGCATGTCT TCCATCACCT TCTTCCTGGC 
TTCCTGGTGA AGATGAGTGG CGACCTGCTG GAGCTGGCCC TGAAGTTGCC CCATGTCGAC 
TACATCGAGG AGGACTCCTC TGTCTTCGCC CAGAGCATCC CATGGAACCT GGAGCGAATT 
ACTCCTGCAC GGTACCGGGC GGATGAATAC CAGCCCCCCA GAGGCAGCCT GGTGGAGGTG 
TATCTCCTAG ACACCAGCAT ACAGAGTGAC CACCGGGAAA TCGAGGGCAG GGTCATGGTC 
ACCGACTTCG AGAGTGTGCC CGAGGAGGAC GGGACCCGCT TCCACAGACA GGCCAGCAAG 
TGTGACAGCC ATGGCACCCA CCTGGCAGGG GTGGTCAGCG GCCGGGATGC CGGCGTGGCC 
AAGGGTGCCG GCCTGCGTAG CCTGCGCGTG CTCAACTGCC AAGGGAAGGG CACGGTCAGC 
GGCACCCTCA TAGGTCTGGA GTTTATTCGG AAAAGCCAGC TGGTCCAGCC CGTGGGGCCA 
CTGGTTGTGC TGCTGCCCCT GGCGGGTGGG TACAGCCGGG TCTTCAACGC CGCCTGCCAG 
CGCCTGGCGA GGGCTGGGGT CGTGCTGGTC ACCGCTGCCG GCAACTTCCG GGACGATGCC 
TGCCTCTACT CTCCAGCCTC GGCTCCCGAG GTCATCACAG TTGGGGCCAC CAATGCCCAG 
GACCAGCCGG TGACCCTGGG GACTTTGGGG ACCAACTTTG GCCGCTGTGT GGACCTCTTT 
GCCCCAGGGG AGGACATCAT TGGTGCCTCC AGCGACTGCA GCACCTGCTT TGTGTCACGG 
AGTGGGACAT CGCAGGCTGC TGCCCACGTG GCTGGCATTG CAGCCATGAT GCTGTCTGCC 
GAGCCGGAGC TCACTCTGGC CGAGTTGAGG CAGAGACTGA TCCACTTCTC TGCCAAAGAT 
GTCATCAATG AGGCCTGGTT CCCTGAGGAC CAGCGGGTAC TGACCCCCAA CCTGGTGGCC 
GCCCTGCCCC CCAGCACCCA CAGGGCAGGT TGGCAGCTGT TTTGCAGGAC TGTGTGGTCA 
GCACACTCGG GGCCTACACG GATGGCCACA GCCGTAGCCC GCTGCGCCCA GGATGAGGAG 
CTGCTGAGCT GCTCCAGTTT CTCCAGGAGT GGGAAGCGGC GGGGCGAGCG CATCGAGGCC 
CAAGGGGGCA AGCGGGTCTG CCGGGCCCAC AACGCTTTTG GGGGTGAGGG TGTCTACGCC 
ATTGCCAGGT GCTGCCTGCT ACCCCAGGTC AACTGCAGCG TCCACACAGC TCCACCAGCT 
GGGGCCAGCA TGGGGACCCG TGTCCACTGC CATCAGCAGG GCCACGTCCT CACAGGCTGC 
AGCTCCCACT GGGAGGTGGA GGACCTTGGC ACCCACAAGC CGCCTGTGCT GAGGCCACGA 
GGTCAGCCCA ACCAGTGTGT GGGCCACAGG GAGGCCAGCA TCCACGCTTC CTGCTGCCAT 
GCCCCAGGTC TGGAATGCAA AGTCAAGGAG CATGGAATCC CGGCCCCTCA GGAGCAGGTT 
ATCGTGGCCT GTGAGGACGG CTGGACCCTG ACCGGCTGCA GTCCCCTCCC TGGGACCTCC 
CATGTCCTGG GGGCCTACGC TGTAGACAAC ACGTGTGTGG TCAGGAGCCG GGACGTCAGC 
ACCACAGGCA GCACCAGCAA AGAAGCCGTG GCAGCCGTTG CCATCTGCTG CCGGAGCCGG 
CACCTGGTGC AGGCCTCCCA AGAGCTCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evidence for positive selection in the C-terminal domain of the cholesterol metabolism gene PCSK9 based on phylogenetic analysis in 14 primate species.
PloS one2(10)e1098(2007 Oct)
Ding K,McDonough SJ,Kullo IJ

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PCSK9 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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