SELENOO cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	SELENOO
Entrez Gene ID	715604
Full Name	selenoprotein O
Synonyms	SELO
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)
Summary	This gene encodes a selenoprotein that is localized to the mitochondria. It is the largest mammalian selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The exact function of this selenoprotein is not known, but it is thought to have redox activity. [provided by RefSeq, Dec 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001159411.1	NP_001152883.1	protein adenylyltransferase SelO, mitochondrial

Pathways from BioSystems

Homologies

	SELO	NP_001152883.1
Oryza sativa (rice)	Os06g0320700	NP_001057514.1
Bos taurus (cattle)	SELO	NP_001156665.1
Mus musculus (house mouse)	Selo	NP_082181.2
Gallus gallus (chicken)	SELO	NP_001108489.1
Arabidopsis thaliana (thale cress)	AT5G13030	NP_196807.2
Xenopus tropicalis (tropical clawed frog)	selo	NP_001135537.2
Rattus norvegicus (Norway rat)	Selo	NP_001078954.1
Pan troglodytes (chimpanzee)	SELO	XP_003317367.2
Homo sapiens (human)	SELO	NP_113642.1
Canis lupus familiaris (dog)	SELO	NP_001131075.1
Danio rerio (zebrafish)	selo	NP_001038336.2

Gene Ontology
Bibliography

Related articles in PubMed

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)

Characterization of mammalian selenoprotein o: a redox-active mitochondrial protein.
Han SJ, Lee BC, Yim SH, Gladyshev VN, Lee SR
PloS one9(4)e95518(2014)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

Characterization of mammalian selenoproteomes.
Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guig? R, Gladyshev VN
Science (New York, N.Y.)300(5624)1439-43(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SELENOO gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SELENOO cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMb03095	NM_001159411.1 Latest version!	Macaca mulatta selenoprotein O (SELENOO), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SELENOO ( NM_001159411.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001152883.1 Macaca mulatta selenoprotein O (SELENOO), mRNA.

Price & Availability↑

CloneID	OMb03095
Clone ID Related Accession (Same CDS sequence)	NM_001159411.1
Accession Version	NM_001159411.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-27
Organism	Macaca mulatta(Rhesus monkey)
Product	protein adenylyltransferase SelO, mitochondrial
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JSUE03005861.1 and JSUE03005862.1. On Apr 18, 2009 this sequence version replaced XM_001112104.1. Sequence Note: This RefSeq record was created using reference genomic sequence. The transcript and the encoded protein are supported by orthologous human data. ##Evidence-Data-START## Transcript exon combination :: JV630380.1, JV698106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688324, SAMEA4688335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCGT ACAGGGCAGC TCTCGGGGGT TCGCTCGCAG CTGCCCGACT CCTGCCCCTC 
GGCCGCTGCC ACCCGTCGCC CGCGCCCGGC TCTACCTTGT CGGGCGCCGC CATGGAGCCC 
GCGCCTTGCT GGCTGGCGGG GCTGCGCTTC GACAACCGCG CCCTGCGCGC GCTGCCCGTG 
GAGGCGCCGC CTCCCGGTCC CGAGGGCGCC CAGTCCGCGC CGCGCCAGGT GCCCGGGGCC 
TGCTTCACCC GCGTGCGGCC CACCCCCCTG CGGCAGCCGC GCCTTGTGGC GCTGTCGGAG 
CCCGCGCTGG CACTGCTGGG CCTGGGCGCG CCGCCCGCAC GCGAGGCCGA GGCCGAGGCC 
GCGCTGTTCT TCAGCGGCAA CGCGCTCCTG CCGGGCGCTG AGCCCGCCGC GCACTGCTAC 
TGCGGCCACC AGTTCGGCCA GTTCGCCGGG CAACTGGGCG ACGGCGCCGC CATGTACTTG 
GGCGAGGTGT GCACGGCGGC CGGCGAGCGC TGGGAGCTGC AGCTCAAGGG CGCTGGGCCC 
ACGCCCTTCT CCAGACAGGC CGACGGTCGC AAGGTCCTGC GGTCAAGCAT CCGGGAGTTC 
CTGTGCAGCG AAGCCATGTT CCACCTGGGG GTCCCCACCA CACGGGCCGG TGCCTGTGTC 
ACGTCCGAGT CCACGGTGGT GCGCGACGTG TTCTATGATG GTAATCCCAA ATATGAACAA 
TGCACGGTTG TGTTGCGTAT AGCTTCCACT TTCATAAGGT TTGGATCCTT TGAGATTTTT 
AAGTCCGCAG ATGAGCACAC AGGGCGTGCA GGCCCCAGCG TGGGGAGGAA CGACATTCGC 
GTGCAGCTGC TTGACTATGT CATCAGCTCC TTTTACCCTG AGATCCAGGC TGCTCACACC 
AGTGACCGCG TGCAGAGAAA CGCTGCCTTC TTCCGGGAGG TGACGCGGCG CACGGCGTGG 
ATGGTGGCTG AGTGGCAGTG CGTGGGCTTC TGCCACGGCG TGCTCAACAC TGACAACATG 
AGCATCCTGG GGCTCACCAT CGACTACGGG CCCTTCGGCT TCCTGGACAG GTATGACCCT 
GACCACGTGT GCAATGCCTC CGACAACACC GGCCGCTACG CATACAGCAA GCAGCCCGAG 
GTGTGCAAGT GGAACCTGCA GAAGCTGGCC GAGGCCCTGC AGCCAGAGCT GCCCCTGGAG 
CTGGGTGAGG CCATCCTGGC CGAGGAGTTT GATGCCGAGT TCCAAAGGCA CTACATGCAG 
AAGATGCGCA GGAAGCTGGG CCTTGTGCAG CTGGAGCTGG AGGAAGACAG GGCGCTGGTG 
TCCAAGCTCC TGGAGACCAT GCACCTGACC GGTGCTGACT TCACAAACAC CTTCTTCTTG 
CTGAGCTCCT TCCCAGTGGA GCTGGAGTCA CCAGGCCTGG CGGAGTTCCT GGCCAGGCTA 
ATGGAGCAGT GTGCCTCCCT GGAGGAGCTG AGGCTGGCCT TCCGGCCCCA GATGGATCCC 
CGGCAGCTAT CCATGATGCT GATGCTGGCA CAGTCAAACC CGCAGCTGTT CGCGCTCATG 
GGCACCCGGG CAGGCATTGC CAGGGAGCTG GAGCGTGTGG AGCAGCAGTC TCGGCTGGAG 
CAGCTGAGCA TGGCAGAGCT GCAGAGCCGG AACCAGGGCC ACTGGGCCGA ATGGCTGCAG 
GCGTACAGAG CCCGGCTGGA CAAGGACCTG GAAGGCGCCG GGGATGCTGC TGCCTGGCAG 
GCTGAGCGTG TGCGCGTGAT GCACGCCAAC AACCCCAAGT ACGTGCTGAG GAACTACATC 
GCGCAGAATG CCATCGAGGC TGCCGAGCGC GGGGACTTCT CAGAGGTGCG GCGGGTGCTG 
AAGCTACTGG AGAACCCTTA CCACTGCGAG GCGGGGGCTG CCACAGATCC CGAGGCCACG 
GAGGCCGACG GGGCGGACGG CAGGCAGCGC TCCTACAGCA GTAAGCCCCC GCTCTGGGCA 
GCCGAACTGT GTGTGACATG ATCTTCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152883.1
CDS	62..2071
Translation	MAAYRAALGGSLAAARLLPLGRCHPSPAPGSTLSGAAMEPAPCWLAGLRFDNRALRALPVEAPPPGPEGAQSAPRQVPGACFTRVRPTPLRQPRLVALSEPALALLGLGAPPAREAEAEAALFFSGNALLPGAEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTAAGERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGVPTTRAGACVTSESTVVRDVFYDGNPKYEQCTVVLRIASTFIRFGSFEIFKSADEHTGRAGPSVGRNDIRVQLLDYVISSFYPEIQAAHTSDRVQRNAAFFREVTRRTAWMVAEWQCVGFCHGVLNTDNMSILGLTIDYGPFGFLDRYDPDHVCNASDNTGRYAYSKQPEVCKWNLQKLAEALQPELPLELGEAILAEEFDAEFQRHYMQKMRRKLGLVQLELEEDRALVSKLLETMHLTGADFTNTFFLLSSFPVELESPGLAEFLARLMEQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLFALMGTRAGIARELERVEQQSRLEQLSMAELQSRNQGHWAEWLQAYRARLDKDLEGAGDAAAWQAERVRVMHANNPKYVLRNYIAQNAIEAAERGDFSEVRRVLKLLENPYHCEAGAATDPEATEADGADGRQRSYSSKPPLWAAELCVT*SS

Target ORF information:

RefSeq Version	NM_001159411.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta selenoprotein O (SELENOO), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159411.1

ORF Insert Sequence:

ATGGCCGCGT ACAGGGCAGC TCTCGGGGGT TCGCTCGCAG CTGCCCGACT CCTGCCCCTC 
GGCCGCTGCC ACCCGTCGCC CGCGCCCGGC TCTACCTTGT CGGGCGCCGC CATGGAGCCC 
GCGCCTTGCT GGCTGGCGGG GCTGCGCTTC GACAACCGCG CCCTGCGCGC GCTGCCCGTG 
GAGGCGCCGC CTCCCGGTCC CGAGGGCGCC CAGTCCGCGC CGCGCCAGGT GCCCGGGGCC 
TGCTTCACCC GCGTGCGGCC CACCCCCCTG CGGCAGCCGC GCCTTGTGGC GCTGTCGGAG 
CCCGCGCTGG CACTGCTGGG CCTGGGCGCG CCGCCCGCAC GCGAGGCCGA GGCCGAGGCC 
GCGCTGTTCT TCAGCGGCAA CGCGCTCCTG CCGGGCGCTG AGCCCGCCGC GCACTGCTAC 
TGCGGCCACC AGTTCGGCCA GTTCGCCGGG CAACTGGGCG ACGGCGCCGC CATGTACTTG 
GGCGAGGTGT GCACGGCGGC CGGCGAGCGC TGGGAGCTGC AGCTCAAGGG CGCTGGGCCC 
ACGCCCTTCT CCAGACAGGC CGACGGTCGC AAGGTCCTGC GGTCAAGCAT CCGGGAGTTC 
CTGTGCAGCG AAGCCATGTT CCACCTGGGG GTCCCCACCA CACGGGCCGG TGCCTGTGTC 
ACGTCCGAGT CCACGGTGGT GCGCGACGTG TTCTATGATG GTAATCCCAA ATATGAACAA 
TGCACGGTTG TGTTGCGTAT AGCTTCCACT TTCATAAGGT TTGGATCCTT TGAGATTTTT 
AAGTCCGCAG ATGAGCACAC AGGGCGTGCA GGCCCCAGCG TGGGGAGGAA CGACATTCGC 
GTGCAGCTGC TTGACTATGT CATCAGCTCC TTTTACCCTG AGATCCAGGC TGCTCACACC 
AGTGACCGCG TGCAGAGAAA CGCTGCCTTC TTCCGGGAGG TGACGCGGCG CACGGCGTGG 
ATGGTGGCTG AGTGGCAGTG CGTGGGCTTC TGCCACGGCG TGCTCAACAC TGACAACATG 
AGCATCCTGG GGCTCACCAT CGACTACGGG CCCTTCGGCT TCCTGGACAG GTATGACCCT 
GACCACGTGT GCAATGCCTC CGACAACACC GGCCGCTACG CATACAGCAA GCAGCCCGAG 
GTGTGCAAGT GGAACCTGCA GAAGCTGGCC GAGGCCCTGC AGCCAGAGCT GCCCCTGGAG 
CTGGGTGAGG CCATCCTGGC CGAGGAGTTT GATGCCGAGT TCCAAAGGCA CTACATGCAG 
AAGATGCGCA GGAAGCTGGG CCTTGTGCAG CTGGAGCTGG AGGAAGACAG GGCGCTGGTG 
TCCAAGCTCC TGGAGACCAT GCACCTGACC GGTGCTGACT TCACAAACAC CTTCTTCTTG 
CTGAGCTCCT TCCCAGTGGA GCTGGAGTCA CCAGGCCTGG CGGAGTTCCT GGCCAGGCTA 
ATGGAGCAGT GTGCCTCCCT GGAGGAGCTG AGGCTGGCCT TCCGGCCCCA GATGGATCCC 
CGGCAGCTAT CCATGATGCT GATGCTGGCA CAGTCAAACC CGCAGCTGTT CGCGCTCATG 
GGCACCCGGG CAGGCATTGC CAGGGAGCTG GAGCGTGTGG AGCAGCAGTC TCGGCTGGAG 
CAGCTGAGCA TGGCAGAGCT GCAGAGCCGG AACCAGGGCC ACTGGGCCGA ATGGCTGCAG 
GCGTACAGAG CCCGGCTGGA CAAGGACCTG GAAGGCGCCG GGGATGCTGC TGCCTGGCAG 
GCTGAGCGTG TGCGCGTGAT GCACGCCAAC AACCCCAAGT ACGTGCTGAG GAACTACATC 
GCGCAGAATG CCATCGAGGC TGCCGAGCGC GGGGACTTCT CAGAGGTGCG GCGGGTGCTG 
AAGCTACTGG AGAACCCTTA CCACTGCGAG GCGGGGGCTG CCACAGATCC CGAGGCCACG 
GAGGCCGACG GGGCGGACGG CAGGCAGCGC TCCTACAGCA GTAAGCCCCC GCTCTGGGCA 
GCCGAACTGT GTGTGACATG ATCTTCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Biology direct9(1)20(2014 Oct)
Zimin AV,Cornish AS,Maudhoo MD,Gibbs RM,Zhang X,Pandey S,Meehan DT,Wipfler K,Bosinger SE,Johnson ZP,Tharp GK,Mar?ais G,Roberts M,Ferguson B,Fox HS,Treangen T,Salzberg SL,Yorke JA,Norgren RB Jr

Characterization of mammalian selenoprotein o: a redox-active mitochondrial protein.
PloS one9(4)e95518(2014)
Han SJ,Lee BC,Yim SH,Gladyshev VN,Lee SR

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

Characterization of mammalian selenoproteomes.
Science (New York, N.Y.)300(5624)1439-43(2003 May)
Kryukov GV,Castellano S,Novoselov SV,Lobanov AV,Zehtab O,Guig? R,Gladyshev VN

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SELENOO cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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