Gene Symbol | IL15 |
Entrez Gene ID | 699616 |
Full Name | interleukin 15 |
Synonyms | IL-15 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » IL15 cDNA ORF clone
Gene Symbol | IL15 |
Entrez Gene ID | 699616 |
Full Name | interleukin 15 |
Synonyms | IL-15 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
XM_015139228.1 | XP_014994714.1 | interleukin-15 isoform X1 |
XM_015139229.2 | XP_014994715.1 | interleukin-15 isoform X1 |
XM_015139230.2 | XP_014994716.1 | interleukin-15 isoform X3 |
XM_015139230.1 | XP_014994716.1 | interleukin-15 isoform X2 |
XM_015139229.1 | XP_014994715.1 | interleukin-15 isoform X1 |
XM_028848015.1 | XP_028703848.1 | interleukin-15 isoform X2 |
NM_001044731.1 | NP_001038196.1 | interleukin-15 precursor |
XM_015139228.2 | XP_014994714.1 | interleukin-15 isoform X1 |
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)
Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates.
Lugli E, Goldman CK, Perera LP, Smedley J, Pung R, Yovandich JL, Creekmore SP, Waldmann TA, Roederer M
Blood116(17)3238-48(2010 Oct)
Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection.
Eberly MD, Kader M, Hassan W, Rogers KA, Zhou J, Mueller YM, Mattapallil MJ, Piatak M Jr, Lifson JD, Katsikis PD, Roederer M, Villinger F, Mattapallil JJ
Journal of immunology (Baltimore, Md. : 1950)182(3)1439-48(2009 Feb)
IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates.
Picker LJ, Reed-Inderbitzin EF, Hagen SI, Edgar JB, Hansen SG, Legasse A, Planer S, Piatak M Jr, Lifson JD, Maino VC, Axthelm MK, Villinger F
The Journal of clinical investigation116(6)1514-24(2006 Jun)
Comparative sequence analysis of cytokine genes from human and nonhuman primates.
Villinger F, Brar SS, Mayne A, Chikkala N, Ansari AA
Journal of immunology (Baltimore, Md. : 1950)155(8)3946-54(1995 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
IL 15 generates a dramatic expansion of short-lived memory CD8 T cells and natural killer in immunocompetent macaques and has long-term effects on the balance of CD4(+) and CD8(+) T cells.
Title: Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates.
IL-15 secretion significantly correlates with the up-regulated expression of CD4 on memory CD4 T cells that is associated with increased permissiveness to simian immunodeficiency virus infection.
Title: Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection.
These data suggest that therapeutic use of IL-15 in the setting of antiretroviral therapy might facilitate specific restoration of the CD4 + T cell compartment.
Title: IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates.
The following IL15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb01716 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139228.1 , XM_015139229.2 , XM_015139229.1 , NM_001044731.1 , XM_015139228.2 | |
Accession Version | NM_001044731.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U19843.1. On or before Aug 31, 2006 this sequence version replaced XM_001091289.1, XM_001091416.1, XM_001091166.1. ##Evidence-Data-START## Transcript exon combination :: U19843.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688330, SAMEA4688331 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001038196.1 |
CDS | 28..516 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001044731.1 |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb01716 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139228.1 , XM_015139229.2 , XM_015139229.1 , NM_001044731.1 , XM_015139228.2 | |
Accession Version | XM_015139228.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804897.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994714.1 |
CDS | 1318..1806 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139228.1 |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb01716 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139228.1 , XM_015139229.2 , XM_015139229.1 , NM_001044731.1 , XM_015139228.2 | |
Accession Version | XM_015139229.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041758.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139229.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994715.1 |
CDS | 832..1320 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139229.2 |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb01716 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139228.1 , XM_015139229.2 , XM_015139229.1 , NM_001044731.1 , XM_015139228.2 | |
Accession Version | XM_015139229.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804897.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994715.1 |
CDS | 831..1319 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139229.1 |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb01716 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139228.1 , XM_015139229.2 , XM_015139229.1 , NM_001044731.1 , XM_015139228.2 | |
Accession Version | XM_015139228.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041758.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139228.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994714.1 |
CDS | 1319..1807 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139228.2 |
1 | ATGAGAATTT CGAAACCACA TTTGAGAAGT GTTTCCATCC AGTGCTACTT GTGTTTACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb34089 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139230.2 , XM_015139230.1 | |
Accession Version | XM_015139230.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041758.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139230.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTATTGG GAACCATAGA TTTGTGCAGC TGTTTCAGTG CAGGGCTCCC TAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994716.1 |
CDS | 1032..1439 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139230.2 |
1 | ATGGTATTGG GAACCATAGA TTTGTGCAGC TGTTTCAGTG CAGGGCTCCC TAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb34089 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139230.2 , XM_015139230.1 | |
Accession Version | XM_015139230.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804897.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTATTGG GAACCATAGA TTTGTGCAGC TGTTTCAGTG CAGGGCTCCC TAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994716.1 |
CDS | 1031..1438 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139230.1 |
1 | ATGGTATTGG GAACCATAGA TTTGTGCAGC TGTTTCAGTG CAGGGCTCCC TAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb85377 | |
Clone ID Related Accession (Same CDS sequence) | XM_028848015.1 | |
Accession Version | XM_028848015.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | interleukin-15 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041758.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCTTGC GCTCGCCCTG CAGGTTCTGC GCCCCAGGAC CCGGCAAGGA CGGAAACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_028703848.1 |
CDS | 262..726 |
Translation |
Target ORF information:
Target ORF information:
|
XM_028848015.1 |
1 | ATGTCCTTGC GCTCGCCCTG CAGGTTCTGC GCCCCAGGAC CCGGCAAGGA CGGAAACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A new rhesus macaque assembly and annotation for next-generation sequencing analyses. |
Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates. |
Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection. |
IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates. |
Comparative sequence analysis of cytokine genes from human and nonhuman primates. |