Gene Symbol | HTR1A |
Entrez Gene ID | 694991 |
Full Name | 5-hydroxytryptamine receptor 1A |
Synonyms | 5-HT1A |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » HTR1A cDNA ORF clone
Gene Symbol | HTR1A |
Entrez Gene ID | 694991 |
Full Name | 5-hydroxytryptamine receptor 1A |
Synonyms | 5-HT1A |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
NM_001198700.1 | NP_001185629.1 | 5-hydroxytryptamine receptor 1A |
NM_001198700.2 | NP_001185629.1 | 5-hydroxytryptamine receptor 1A |
Homo sapiens (human) | HTR1A | NP_000515.2 |
Mus musculus (house mouse) | Htr1a | NP_032334.2 |
Gallus gallus (chicken) | HTR1A | NP_001163999.1 |
Pan troglodytes (chimpanzee) | HTR1A | NP_001129094.1 |
Canis lupus familiaris (dog) | HTR1A | NP_001012397.1 |
Anopheles gambiae (African malaria mosquito) | GPR5HT1A | XP_308623.4 |
Xenopus tropicalis (tropical clawed frog) | htr1a | XP_004910432.1 |
Bos taurus (cattle) | HTR1A | XP_002696350.1 |
Danio rerio (zebrafish) | htr1aa | NP_001116793.1 |
Drosophila melanogaster (fruit fly) | 5-HT1A | NP_725849.1 |
Caenorhabditis elegans (roundworm) | ser-4 | NP_497452.1 |
Rattus norvegicus (Norway rat) | Htr1a | NP_036717.1 |
HTR1A | XP_001083407.1 |
The effects of chronic alcohol self-administration on serotonin-1A receptor binding in nonhuman primates.
Hillmer AT, Wooten DW, Tudorascu DL, Barnhart TE, Ahlers EO, Resch LM, Larson JA, Converse AK, Moore CF, Schneider ML, Christian BT
Drug and alcohol dependence144119-26(2014 Nov)
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)
Characterization of [(11)C]Cimbi-36 as an agonist PET radioligand for the 5-HT(2A) and 5-HT(2C) receptors in the nonhuman primate brain.
Finnema SJ, Stepanov V, Ettrup A, Nakao R, Amini N, Svedberg M, Lehmann C, Hansen M, Knudsen GM, Halldin C
NeuroImage84342-53(2014 Jan)
Serotonin transporter genotype affects serotonin 5-HT1A binding in primates.
Christian BT, Wooten DW, Hillmer AT, Tudorascu DL, Converse AK, Moore CF, Ahlers EO, Barnhart TE, Kalin NH, Barr CS, Schneider ML
The Journal of neuroscience : the official journal of the Society for Neuroscience33(6)2512-6(2013 Feb)
The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype.
Embree M, Michopoulos V, Votaw JR, Voll RJ, Mun J, Stehouwer JS, Goodman MM, Wilson ME, S?nchez MM
Neuroscience22883-100(2013 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Increased levels of 5-HT1A receptor binding were seen in the raphe nuclei following chronic ethanol self-administration.
Title: The effects of chronic alcohol self-administration on serotonin-1A receptor binding in nonhuman primates.
Cimbi-36 is the first agonist radioligand suitable for examination of 5-HT2A receptors in the cortical regions and of 5-HT2C receptors in the choroid plexus of the primate brain.
Title: Characterization of [(11)C]Cimbi-36 as an agonist PET radioligand for the 5-HT(2A) and 5-HT(2C) receptors in the nonhuman primate brain.
Significantly lower 5-HT1A binding is found in s-carrier subjects (5-HTTLPR genotype) in both cortical brain regions and the raphe nuclei.
Title: Serotonin transporter genotype affects serotonin 5-HT1A binding in primates.
5-HT1A receptor levels increase during development in the female brain from pre-to peripuberty.
Title: The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype.
5HT1A receptor may lose sensitivity to the suppressive effect of estradiol after 5 months, whereas the 5HT2C receptor increases, however, addition of progesterone in the EP5 regimen maintains the regulatory effects
Title: Differential effects of ovarian steroids and raloxifene on serotonin 1A and 2C receptor protein expression in macaques.
The following HTR1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HTR1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb04744 | |
Clone ID Related Accession (Same CDS sequence) | NM_001198700.1 | |
Accession Version | NM_001198700.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-28 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | 5-hydroxytryptamine receptor 1A | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JSUE03036097.1. On Nov 3, 2010 this sequence version replaced XM_001083407.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
1 | ATGGATGTGC TCAGCCCTGG TCAGGGCAAC AACACCACAT CACCACCGGG TCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001185629.1 |
CDS | 423..1688 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001198700.1 |
1 | ATGGATGTGC TCAGCCCTGG TCAGGGCAAC AACACCACAT CACCACCGGG TCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb94782 | |
Clone ID Related Accession (Same CDS sequence) | NM_001198700.2 | |
Accession Version | NM_001198700.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-11 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | 5-hydroxytryptamine receptor 1A | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from QNVO02000392.1. On Dec 12, 2019 this sequence version replaced NM_001198700.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: JV615151.1 [ECO:0000345] ##Evidence-Data-END## |
1 | ATGGATGTGC TCAGCCCTGG TCAGGGCAAC AACACCACAT CACCACCGGG TCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001185629.1 |
CDS | 423..1688 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001198700.2 |
1 | ATGGATGTGC TCAGCCCTGG TCAGGGCAAC AACACCACAT CACCACCGGG TCCCTTTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The effects of chronic alcohol self-administration on serotonin-1A receptor binding in nonhuman primates. |
A new rhesus macaque assembly and annotation for next-generation sequencing analyses. |
Characterization of [(11)C]Cimbi-36 as an agonist PET radioligand for the 5-HT(2A) and 5-HT(2C) receptors in the nonhuman primate brain. |
Serotonin transporter genotype affects serotonin 5-HT1A binding in primates. |
The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. |