Gene Symbol | CXCL12 |
Entrez Gene ID | 574334 |
Full Name | C-X-C motif chemokine ligand 12 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » CXCL12 cDNA ORF clone
Gene Symbol | CXCL12 |
Entrez Gene ID | 574334 |
Full Name | C-X-C motif chemokine ligand 12 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
XM_015146892.1 | XP_015002378.1 | stromal cell-derived factor 1 isoform X1 |
XM_015146893.1 | XP_015002379.1 | stromal cell-derived factor 1 isoform X2 |
XM_015146894.1 | XP_015002380.1 | stromal cell-derived factor 1 isoform X3 |
XM_015146892.2 | XP_015002378.1 | stromal cell-derived factor 1 isoform X1 |
XM_028853226.1 | XP_028709059.1 | stromal cell-derived factor 1 isoform X3 |
XM_015146893.2 | XP_015002379.1 | stromal cell-derived factor 1 isoform X2 |
XM_015146894.2 | XP_015002380.1 | stromal cell-derived factor 1 isoform X4 |
NM_001032934.1 | NP_001028106.1 | stromal cell-derived factor 1 precursor |
Homo sapiens (human) | CXCL12 | NP_001171605.1 |
Rattus norvegicus (Norway rat) | Cxcl12 | NP_001029055.1 |
Mus musculus (house mouse) | Cxcl12 | NP_001012495.1 |
Gallus gallus (chicken) | CXCL12 | NP_989841.1 |
Bos taurus (cattle) | CXCL12 | NP_001106645.1 |
Pan troglodytes (chimpanzee) | LOC741624 | XP_001157443.2 |
CXCL12 | NP_001028106.1 | |
Canis lupus familiaris (dog) | CXCL12 | NP_001121569.1 |
Xenopus tropicalis (tropical clawed frog) | cxcl12 | NP_001015764.1 |
TGF-?1 enhances SDF-1-induced migration and tube formation of choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7 expression.
Feng YF, Yuan F, Guo H, Wu WZ
Molecular and cellular biochemistry397(1-2)131-8(2014 Dec)
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)
Glial cells activation potentially contributes to the upregulation of stromal cell-derived factor-1? after optic nerve crush in rats.
Yang XT, Pan DC, Chen ET, Bi YY, Feng DF
Neurochemical research38(10)1996-2008(2013 Oct)
CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration, survival and tube formation of choroid-retinal endothelial cells.
Jin J, Zhao WC, Yuan F
Ophthalmic research50(1)6-12(2013)
Molecular cloning and sequencing of 25 different rhesus macaque chemokine cDNAs reveals evolutionary conservation among C, CC, CXC, AND CX3C families of chemokines.
Basu S, Schaefer TM, Ghosh M, Fuller CL, Reinhart TA
Cytokine18(3)140-8(2002 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
these results demonstrate that a cross-talk exists between the TGF-beta1 and SDF-1 pathways in choroid-retinal endothelial cells
Title: TGF-?1 enhances SDF-1-induced migration and tube formation of choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7 expression.
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
Title: Glial cells activation potentially contributes to the upregulation of stromal cell-derived factor-1? after optic nerve crush in rats.
The CXCR7/CXCR4/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
Title: CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration, survival and tube formation of choroid-retinal endothelial cells.
The following CXCL12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCL12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb04743 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032934.1 | |
Accession Version | NM_001032934.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 270bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-01 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF449283.1. ##Evidence-Data-START## Transcript exon combination :: DR768194.1, DR771647.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688330, SAMEA4688357 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001028106.1 |
CDS | 1..270 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001032934.1 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb39340 | |
Clone ID Related Accession (Same CDS sequence) | XM_015146892.1 , XM_015146892.2 | |
Accession Version | XM_015146892.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805167.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015002378.1 |
CDS | 97..456 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015146892.1 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb39340 | |
Clone ID Related Accession (Same CDS sequence) | XM_015146892.1 , XM_015146892.2 | |
Accession Version | XM_015146892.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041762.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015146892.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015002378.1 |
CDS | 106..465 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015146892.2 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb39341 | |
Clone ID Related Accession (Same CDS sequence) | XM_015146893.1 , XM_015146893.2 | |
Accession Version | XM_015146893.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805167.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015002379.1 |
CDS | 97..378 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015146893.1 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb39341 | |
Clone ID Related Accession (Same CDS sequence) | XM_015146893.1 , XM_015146893.2 | |
Accession Version | XM_015146893.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041762.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015146893.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015002379.1 |
CDS | 104..385 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015146893.2 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb39342 | |
Clone ID Related Accession (Same CDS sequence) | XM_015146894.1 , XM_015146894.2 | |
Accession Version | XM_015146894.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805167.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015002380.1 |
CDS | 97..519 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015146894.1 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb39342 | |
Clone ID Related Accession (Same CDS sequence) | XM_015146894.1 , XM_015146894.2 | |
Accession Version | XM_015146894.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041762.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015146894.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_015002380.1 |
CDS | 105..527 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015146894.2 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb91938 | |
Clone ID Related Accession (Same CDS sequence) | XM_028853226.1 | |
Accession Version | XM_028853226.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 270bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | stromal cell-derived factor 1 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041762.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_028709059.1 |
CDS | 104..373 |
Translation |
Target ORF information:
Target ORF information:
|
XM_028853226.1 |
1 | ATGAACGCCA AGGTCGTGGT CGTGCTGGCC CTCGTGCTGA CCACGCTCTG CCTCAGCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
TGF-?1 enhances SDF-1-induced migration and tube formation of choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7 expression. |
A new rhesus macaque assembly and annotation for next-generation sequencing analyses. |
Glial cells activation potentially contributes to the upregulation of stromal cell-derived factor-1? after optic nerve crush in rats. |
CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration, survival and tube formation of choroid-retinal endothelial cells. |
Molecular cloning and sequencing of 25 different rhesus macaque chemokine cDNAs reveals evolutionary conservation among C, CC, CXC, AND CX3C families of chemokines. |