Gene Symbol | TLR7 |
Entrez Gene ID | 574291 |
Full Name | toll like receptor 7 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » TLR7 cDNA ORF clone
Gene Symbol | TLR7 |
Entrez Gene ID | 574291 |
Full Name | toll like receptor 7 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
NM_001130426.2 | NP_001123898.1 | toll-like receptor 7 |
Homo sapiens (human) | TLR7 | NP_057646.1 |
Pan troglodytes (chimpanzee) | TLR7 | NP_001123605.1 |
Canis lupus familiaris (dog) | TLR7 | NP_001041589.1 |
Danio rerio (zebrafish) | tlr7 | XP_003199309.1 |
TLR7 | NP_001123898.1 | |
Bos taurus (cattle) | TLR7 | NP_001028933.1 |
Mus musculus (house mouse) | Tlr7 | NP_573474.1 |
Gallus gallus (chicken) | TLR7 | NP_001011688.1 |
Rattus norvegicus (Norway rat) | Tlr7 | NP_001091051.1 |
Xenopus tropicalis (tropical clawed frog) | tlr7 | NP_001120883.1 |
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)
Whole blood stimulation with Toll-like receptor (TLR)-7/8 and TLR-9 agonists induces interleukin-12p40 expression in plasmacytoid dendritic cells in rhesus macaques but not in humans.
Koopman G, Beenhakker N, Burm S, Bouwhuis O, Bajramovic J, Sommandas V, Mudde G, Mooij P, 't Hart BA, Bogers WM
Clinical and experimental immunology174(1)161-71(2013 Oct)
Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation.
Gujer C, Sundling C, Seder RA, Karlsson Hedestam GB, Lor? K
Immunology134(3)257-69(2011 Nov)
Association of TLR7 variants with AIDS-like disease and AIDS vaccine efficacy in rhesus macaques.
Siddiqui RA, Krawczak M, Platzer M, Sauermann U
PloS one6(10)e25474(2011)
Natural selection in the TLR-related genes in the course of primate evolution.
Nakajima T, Ohtani H, Satta Y, Uno Y, Akari H, Ishida T, Kimura A
Immunogenetics60(12)727-35(2008 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
In contrast to humans, plasmacytoid dendritic cells in rhesus macaques express the interleukin (IL)-12p40 subunit in response to TLR-7/8 as well as TLR-9 agonist stimulation.
Title: Whole blood stimulation with Toll-like receptor (TLR)-7/8 and TLR-9 agonists induces interleukin-12p40 expression in plasmacytoid dendritic cells in rhesus macaques but not in humans.
Data suggest that the response pattern of human and rhesus B cells and pDCs to TLR7/8 and TLR9 is similar, although some differences in the cell surface phenotype of the differentiating cells exist.
Title: Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation.
analyzed polymorphisms in TLR7 gene in the rhesus macaque model of AIDS; in c.13A carriers, neither set-point viral load nor survival time were related to c.-17C>T genotype; in c.13G carriers c.-17C allele wasassociated with prolonged survival
Title: Association of TLR7 variants with AIDS-like disease and AIDS vaccine efficacy in rhesus macaques.
The following TLR7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb04806 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130426.2 | |
Accession Version | NM_001130426.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3150bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-11 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | toll-like receptor 7 | |
Comment | Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JU472848.1, AB445665.1, JU487786.1 and QNVO02003165.1. On Mar 3, 2017 this sequence version replaced NM_001130426.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: JU472848.1, JV716446.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688317, SAMEA4688321 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATGTTTC CAGTGTGGAC ACTGAAGAGA CAAATTCTTA TCCTTTTTAA CATAATCCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123898.1 |
CDS | 139..3288 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130426.2 |
1 | ATGATGTTTC CAGTGTGGAC ACTGAAGAGA CAAATTCTTA TCCTTTTTAA CATAATCCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A new rhesus macaque assembly and annotation for next-generation sequencing analyses. |
Whole blood stimulation with Toll-like receptor (TLR)-7/8 and TLR-9 agonists induces interleukin-12p40 expression in plasmacytoid dendritic cells in rhesus macaques but not in humans. |
Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation. |
Association of TLR7 variants with AIDS-like disease and AIDS vaccine efficacy in rhesus macaques. |
Natural selection in the TLR-related genes in the course of primate evolution. |