Gene Symbol | LDLR |
Entrez Gene ID | 574283 |
Full Name | low density lipoprotein receptor |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » LDLR cDNA ORF clone
Gene Symbol | LDLR |
Entrez Gene ID | 574283 |
Full Name | low density lipoprotein receptor |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
XM_028838328.1 | XP_028694161.1 | low-density lipoprotein receptor isoform X1 |
XM_015122900.2 | XP_014978386.2 | low-density lipoprotein receptor isoform X2 |
NM_001032906.1 | NP_001028078.1 | low-density lipoprotein receptor precursor |
XM_015122900.1 | XP_014978386.1 | low-density lipoprotein receptor isoform X1 |
Bos taurus (cattle) | LDLR | NP_001160002.1 |
Danio rerio (zebrafish) | ldlra | NP_001025454.1 |
Homo sapiens (human) | LDLR | NP_000518.1 |
LDLR | NP_001028078.1 | |
Xenopus tropicalis (tropical clawed frog) | LOC100495826 | XP_002942891.1 |
Canis lupus familiaris (dog) | LDLR | XP_005632926.1 |
Pan troglodytes (chimpanzee) | LDLR | XP_001167447.1 |
Mus musculus (house mouse) | Ldlr | NP_034830.2 |
Rattus norvegicus (Norway rat) | Ldlr | NP_786938.1 |
Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process.
Tserentsoodol N, Sztein J, Campos M, Gordiyenko NV, Fariss RN, Lee JW, Fliesler SJ, Rodriguez IR
Molecular vision121306-18(2006 Oct)
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia.
Nomura S, Merched A, Nour E, Dieker C, Oka K, Chan L
Gene therapy11(20)1540-8(2004 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Retina is capable of rapid uptake of circulating LDL via LDLR-mediated process primarily occurring in retinal pigment epithelium and also possibly Muller cells.
Title: Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process.
The following LDLR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LDLR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb00544 | |
Clone ID Related Accession (Same CDS sequence) | NM_001032906.1 | |
Accession Version | NM_001032906.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2562bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-27 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | low-density lipoprotein receptor precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY466854.1. ##Evidence-Data-START## Transcript exon combination :: AY466854.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA4688315, SAMEA4688317 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCGGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001028078.1 |
CDS | 1..2562 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001032906.1 |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCGGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb53006 | |
Clone ID Related Accession (Same CDS sequence) | XM_015122900.1 | |
Accession Version | XM_015122900.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2583bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | low-density lipoprotein receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805752.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCAGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014978386.1 |
CDS | 1152..3734 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015122900.1 |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCAGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb75363 | |
Clone ID Related Accession (Same CDS sequence) | XM_028838328.1 | |
Accession Version | XM_028838328.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | low-density lipoprotein receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041772.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCGGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_028694161.1 |
CDS | 659..3070 |
Translation |
Target ORF information:
Target ORF information:
|
XM_028838328.1 |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCGGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb75364 | |
Clone ID Related Accession (Same CDS sequence) | XM_015122900.2 | |
Accession Version | XM_015122900.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2583bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | low-density lipoprotein receptor isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041772.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015122900.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCGGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014978386.2 |
CDS | 37..2619 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015122900.2 |
1 | ATGGGGCCCT GGGGCTGGAA ACTGCGCTGG ACCGTCGCCT TCCTCCTCGC CGCGGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process. |
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia. |