Khdc1b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Khdc1b
Entrez Gene ID	98582
Full Name	KH domain containing 1B
Synonyms	AU014713,AU015226,AU024076,AY238603,C85331,C86372,C88118,Khdc1,Khdc1c
General protein information	Preferred Names KH domain containing 1B Names KH homology domain-containing protein 1B KH homology domain containing 1 KH homology domain containing 1B oocyte-specific Khdc1 peptidase M20 domain containing 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 A4

mRNA and Protein(s)

mRNA	Protein	Name
NM_001113187.1	NP_001106658.1	KH homology domain-containing protein 1B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Khdc1c	NP_001029076.1
	LOC715519	XP_001112152.1
Mus musculus (house mouse)	Khdc1b	NP_001106658.1
Rattus norvegicus (Norway rat)	Khdc1c	XP_002730056.1
Homo sapiens (human)	KHDC1L	NP_001119535.1
Pan troglodytes (chimpanzee)	KHDC1L	XP_001140525.1
Mus musculus (house mouse)	Khdc1a	NP_899145.2
	LOC719990	XP_001118054.1

Gene Ontology
Bibliography

Related articles in PubMed

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.
Yu C, Ji SY, Dang YJ, Sha QQ, Yuan YF, Zhou JJ, Yan LY, Qiao J, Tang F, Fan HY
Cell research26(3)275-87(2016 Mar)

KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos.
Cai C, Tamai K, Molyneaux K
Molecular biology of the cell21(18)3137-48(2010 Sep)

Atypical structure and phylogenomic evolution of the new eutherian oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family.
Pierre A, Gautier M, Callebaut I, Bontoux M, Jeanpierre E, Pontarotti P, Monget P
Genomics90(5)583-94(2007 Nov)

Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor.
Rajpal A, Cho YA, Yelent B, Koza-Taylor PH, Li D, Chen E, Whang M, Kang C, Turi TG, Winoto A
The EMBO journal22(24)6526-36(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that KHDC1B, via its interaction with mCEPB1, may regulate translation of mRNA targets required for oocyte maturation.
Title: KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos.

The following Khdc1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Khdc1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04937	NM_001113187.1 Latest version!	Mus musculus KH domain containing 1B (Khdc1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Khdc1b ( NM_001113187.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001106658.1 Mus musculus KH domain containing 1B (Khdc1b), mRNA.

Price & Availability↑

CloneID	OMu04937
Clone ID Related Accession (Same CDS sequence)	NM_001113187.1
Accession Version	NM_001113187.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Mus musculus(house mouse)
Product	KH homology domain-containing protein 1B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK139842.1, BG081161.2 and CJ203626.1. On or before Dec 29, 2007 this sequence version replaced XR_031792.1, XR_035202.1, XR_031927.1. ##Evidence-Data-START## Transcript exon combination :: AK139842.1, DN154718.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGAGTGACC TCCGCAGGAA GGGATGGTGG AATGTGCCTG ACTACTTCTA CAGCCCACTG 
GTGTTTGACA TGGAAGAGGA CCAGGAAGAC TACATATTTG GCCCTGATGA TGAATACCTT 
CACACCCTGG AGGTCCACAG CAACACCCTC ATCCAGCTGG AGAGATGGTT CTCACCCACA 
GGCCAAACCC GAGTCACTGT GGTGGGGCCA CTTAAGGCAA GGCTGTGGGT GATGGACATG 
ATCAGAAAAG TGGGGAGTAA GAACACTCTC GATAAAATTA AAGGCAAGTT GATGCTACTC 
CATATCCGGA GTCATCCTCT GACGGATCAA GACCTGCAGA TTCATCTGAT ATCAGGGAGC 
AGTTGTTGGT TCCCTGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106658.1
CDS	382..762
Translation	MSDLRRKGWWNVPDYFYSPLVFDMEEDQEDYIFGPDDEYLHTLEVHSNTLIQLERWFSPTGQTRVTVVGPLKARLWVMDMIRKVGSKNTLDKIKGKLMLLHIRSHPLTDQDLQIHLISGSSCWFPD

Target ORF information:

RefSeq Version	NM_001113187.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus KH domain containing 1B (Khdc1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113187.1

ORF Insert Sequence:

ATGAGTGACC TCCGCAGGAA GGGATGGTGG AATGTGCCTG ACTACTTCTA CAGCCCACTG 
GTGTTTGACA TGGAAGAGGA CCAGGAAGAC TACATATTTG GCCCTGATGA TGAATACCTT 
CACACCCTGG AGGTCCACAG CAACACCCTC ATCCAGCTGG AGAGATGGTT CTCACCCACA 
GGCCAAACCC GAGTCACTGT GGTGGGGCCA CTTAAGGCAA GGCTGTGGGT GATGGACATG 
ATCAGAAAAG TGGGGAGTAA GAACACTCTC GATAAAATTA AAGGCAAGTT GATGCTACTC 
CATATCCGGA GTCATCCTCT GACGGATCAA GACCTGCAGA TTCATCTGAT ATCAGGGAGC 
AGTTGTTGGT TCCCTGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.
Cell research26(3)275-87(2016 Mar)
Yu C,Ji SY,Dang YJ,Sha QQ,Yuan YF,Zhou JJ,Yan LY,Qiao J,Tang F,Fan HY

KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos.
Molecular biology of the cell21(18)3137-48(2010 Sep)
Cai C,Tamai K,Molyneaux K

Atypical structure and phylogenomic evolution of the new eutherian oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family.
Genomics90(5)583-94(2007 Nov)
Pierre A,Gautier M,Callebaut I,Bontoux M,Jeanpierre E,Pontarotti P,Monget P

Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor.
The EMBO journal22(24)6526-36(2003 Dec)
Rajpal A,Cho YA,Yelent B,Koza-Taylor PH,Li D,Chen E,Whang M,Kang C,Turi TG,Winoto A