Gprc5d cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gprc5d
Entrez Gene ID	93746
Full Name	G protein-coupled receptor, family C, group 5, member D
General protein information	Preferred Names G protein-coupled receptor, family C, group 5, member D Names G-protein coupled receptor family C group 5 member D
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 G1

mRNA and Protein(s)

mRNA	Protein	Name
NM_053118.1	NP_444348.1	G-protein coupled receptor family C group 5 member D isoform 2
NM_001205396.1	NP_001192325.1	G-protein coupled receptor family C group 5 member D isoform 1

Pathways from BioSystems

Homologies

	GPRC5D	XP_001087385.2
Homo sapiens (human)	GPRC5D	NP_061124.1
Rattus norvegicus (Norway rat)	Gprc5d	NP_001102724.1
Pan troglodytes (chimpanzee)	GPRC5D	XP_001154995.1
Canis lupus familiaris (dog)	GPRC5D	XP_543806.3
Bos taurus (cattle)	GPRC5D	NP_001098882.1
Mus musculus (house mouse)	Gprc5d	NP_001192325.1

Gene Ontology
Bibliography

Related articles in PubMed

Gpr158 mediates osteocalcin's regulation of cognition.
Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G
The Journal of experimental medicine214(10)2859-2873(2017 Oct)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Normal lung development in RAIG1-deficient mice despite unique lung epithelium-specific expression.
Xu J, Tian J, Shapiro SD
American journal of respiratory cell and molecular biology32(5)381-7(2005 May)

The RAIG family member, GPRC5D, is associated with hard-keratinized structures.
Inoue S, Nambu T, Shimomura T
The Journal of investigative dermatology122(3)565-73(2004 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GPRC5D is involed in the regulation of keratin synthesis in hard epithelial tissue.
Title: The RAIG family member, GPRC5D, is associated with hard-keratinized structures.

The following Gprc5d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gprc5d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09134	NM_053118.1 Latest version!	Mus musculus G protein-coupled receptor, family C, group 5, member D (Gprc5d), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu03061	NM_001205396.1 Latest version!	Mus musculus G protein-coupled receptor, family C, group 5, member D (Gprc5d), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gprc5d ( NM_053118.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_444348.1 Mus musculus G protein-coupled receptor, family C, group 5, member D (Gprc5d), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu09134
Clone ID Related Accession (Same CDS sequence)	NM_053118.1
Accession Version	NM_053118.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	G-protein coupled receptor family C group 5 member D isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF218809.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AF218809.1, BC119192.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTATGAGG ACTGCGTGAA GTCCACAGAA GACTATTACC TCTTCTGTGA CAACGAGGGG 
CCATGGGCCA TTGTTCTGGA GTCCTTGGCA GTGATTGGCA TAGTGGTTAC CATATTGCTA 
CTCCTGGCAT TTCTGTTCCT CATGCGGAAG GTTCAGGACT GCAGCCAGTG GAACGTGCTT 
CCCACTCAGT TCCTCTTCCT GCTGGCTGTG CTCGGGCTCT TCGGACTTAC TTTTGCCTTC 
ATCATCCAAC TCAACCATCA AACTGCCCCT GTTCGCTACT TCCTCTTTGG GGTTCTCTTT 
GCTATCTGCT TCTCCTGCCT CCTGGCTCAT GCCTCCAACC TGGTGAAGCT GGTCCGGGGT 
AGAGTCTCCT TCTGCTGGAC AACAATTCTG TTCATTGCTA TCGGTGTCAG CCTGTTGCAG 
ACCATCATTG CGATAGAGTA TGTGACCCTC ATCATGACCA GAGGCTTGAT GTTCGAGCAT 
ATGACACCGT ATCAGCTCAA TGTGGACTTT GTCTGTCTCC TGATCTATGT CCTCTTCCTG 
ATGGCCCTCA CTTTCTTCGT CTCCAAGGCC ACCTTCTGTG GCCCATGTGA GAACTGGAAA 
CAGCACGGAA GGCTCATATT TGCTACTGTG CTGGTCTCTA TCATTATCTG GGTGGTGTGG 
ATCTCCATGC TCTTGAGAGG CAACCCCCAG CTCCAGCGAC AGCCCCACTG GGACGATGCA 
GTCATCTGCA TTGGCCTGGT CACCAACGCT TGGGTCTTCC TGCTGATCTA CATCATCCCT 
GAGCTGAGCA TACTCTACAG GTCATGTAGG CAGGAGTGTC CTACACAAGG CAACGTCTGC 
CAGGTCCCTG TCTACCAACG CAGCTTCAGG ATGGATACCC AGGAACCCAC CAGAGAGTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444348.1
CDS	148..1050
Translation	MYEDCVKSTEDYYLFCDNEGPWAIVLESLAVIGIVVTILLLLAFLFLMRKVQDCSQWNVLPTQFLFLLAVLGLFGLTFAFIIQLNHQTAPVRYFLFGVLFAICFSCLLAHASNLVKLVRGRVSFCWTTILFIAIGVSLLQTIIAIEYVTLIMTRGLMFEHMTPYQLNVDFVCLLIYVLFLMALTFFVSKATFCGPCENWKQHGRLIFATVLVSIIIWVVWISMLLRGNPQLQRQPHWDDAVICIGLVTNAWVFLLIYIIPELSILYRSCRQECPTQGNVCQVPVYQRSFRMDTQEPTREC

Target ORF information:

RefSeq Version	NM_053118.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor, family C, group 5, member D (Gprc5d), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053118.1

ORF Insert Sequence:

ATGTATGAGG ACTGCGTGAA GTCCACAGAA GACTATTACC TCTTCTGTGA CAACGAGGGG 
CCATGGGCCA TTGTTCTGGA GTCCTTGGCA GTGATTGGCA TAGTGGTTAC CATATTGCTA 
CTCCTGGCAT TTCTGTTCCT CATGCGGAAG GTTCAGGACT GCAGCCAGTG GAACGTGCTT 
CCCACTCAGT TCCTCTTCCT GCTGGCTGTG CTCGGGCTCT TCGGACTTAC TTTTGCCTTC 
ATCATCCAAC TCAACCATCA AACTGCCCCT GTTCGCTACT TCCTCTTTGG GGTTCTCTTT 
GCTATCTGCT TCTCCTGCCT CCTGGCTCAT GCCTCCAACC TGGTGAAGCT GGTCCGGGGT 
AGAGTCTCCT TCTGCTGGAC AACAATTCTG TTCATTGCTA TCGGTGTCAG CCTGTTGCAG 
ACCATCATTG CGATAGAGTA TGTGACCCTC ATCATGACCA GAGGCTTGAT GTTCGAGCAT 
ATGACACCGT ATCAGCTCAA TGTGGACTTT GTCTGTCTCC TGATCTATGT CCTCTTCCTG 
ATGGCCCTCA CTTTCTTCGT CTCCAAGGCC ACCTTCTGTG GCCCATGTGA GAACTGGAAA 
CAGCACGGAA GGCTCATATT TGCTACTGTG CTGGTCTCTA TCATTATCTG GGTGGTGTGG 
ATCTCCATGC TCTTGAGAGG CAACCCCCAG CTCCAGCGAC AGCCCCACTG GGACGATGCA 
GTCATCTGCA TTGGCCTGGT CACCAACGCT TGGGTCTTCC TGCTGATCTA CATCATCCCT 
GAGCTGAGCA TACTCTACAG GTCATGTAGG CAGGAGTGTC CTACACAAGG CAACGTCTGC 
CAGGTCCCTG TCTACCAACG CAGCTTCAGG ATGGATACCC AGGAACCCAC CAGAGAGTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gprc5d ( NM_001205396.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001192325.1 Mus musculus G protein-coupled receptor, family C, group 5, member D (Gprc5d), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu03061
Clone ID Related Accession (Same CDS sequence)	NM_001205396.1
Accession Version	NM_001205396.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	G-protein coupled receptor family C group 5 member D isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC140287.3, AK137739.1 and AF218809.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK137739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTATGAGG ACTGCGTGAA GTCCACAGAA GACTATTACC TCTTCTGTGA CAACGAGGGG 
CCATGGGCCA TTGTTCTGGA GTCCTTGGCA GTGATTGGCA TAGTGGTTAC CATATTGCTA 
CTCCTGGCAT TTCTGTTCCT CATGCGGAAG GTTCAGGACT GCAGCCAGTG GAACGTGCTT 
CCCACTCAGT TCCTCTTCCT GCTGGCTGTG CTCGGGCTCT TCGGACTTAC TTTTGCCTTC 
ATCATCCAAC TCAACCATCA AACTGCCCCT GTTCGCTACT TCCTCTTTGG GGTTCTCTTT 
GCTATCTGCT TCTCCTGCCT CCTGGCTCAT GCCTCCAACC TGGTGAAGCT GGTCCGGGGT 
AGAGTCTCCT TCTGCTGGAC AACAATTCTG TTCATTGCTA TCGGTGTCAG CCTGTTGCAG 
ACCATCATTG CGATAGAGTA TGTGACCCTC ATCATGACCA GAGGCTTGAT GTTCGAGCAT 
ATGACACCGT ATCAGCTCAA TGTGGACTTT GTCTGTCTCC TGATCTATGT CCTCTTCCTG 
ATGGCCCTCA CTTTCTTCGT CTCCAAGGCC ACCTTCTGTG GCCCATGTGA GAACTGGAAA 
CAGCACGGAA GGCTCATATT TGCTACTGTG CTGGTCTCTA TCATTATCTG GGTGGTGTGG 
ATCTCCATGC TCTTGAGAGG CAACCCCCAG CTCCAGCGAC AGCCCCACTG GGACGATGCA 
GTCATCTGCA TTGGCCTGGT CACCAACGCT TGGGTCTTCC TGCTGATCTA CATCATCCCT 
GAGCTGAGCA TACTCTACAG GTCATGTAGG CAGGAGTGTC CTACACAAGG CAACGTCTGC 
CAGGTCCCTG TCTACCAACG CAGCTTCAGG ATGGATACCC AGGAACCCAC CAGAGCCCGA 
GACAGTGATG GAGCTCAGGA GGATGTAGCA CTAACTGCAT ATGGTACTCC CATTCAGCTG 
CAGAGTGCTG ATCCCAGCCG GGAGTATCTC ATCCCATCAG CTACACTAAG CCCACAGCAA 
GATGCAGGAT TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001192325.1
CDS	148..1182
Translation	MYEDCVKSTEDYYLFCDNEGPWAIVLESLAVIGIVVTILLLLAFLFLMRKVQDCSQWNVLPTQFLFLLAVLGLFGLTFAFIIQLNHQTAPVRYFLFGVLFAICFSCLLAHASNLVKLVRGRVSFCWTTILFIAIGVSLLQTIIAIEYVTLIMTRGLMFEHMTPYQLNVDFVCLLIYVLFLMALTFFVSKATFCGPCENWKQHGRLIFATVLVSIIIWVVWISMLLRGNPQLQRQPHWDDAVICIGLVTNAWVFLLIYIIPELSILYRSCRQECPTQGNVCQVPVYQRSFRMDTQEPTRARDSDGAQEDVALTAYGTPIQLQSADPSREYLIPSATLSPQQDAGL

Target ORF information:

RefSeq Version	NM_001205396.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus G protein-coupled receptor, family C, group 5, member D (Gprc5d), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001205396.1

ORF Insert Sequence:

ATGTATGAGG ACTGCGTGAA GTCCACAGAA GACTATTACC TCTTCTGTGA CAACGAGGGG 
CCATGGGCCA TTGTTCTGGA GTCCTTGGCA GTGATTGGCA TAGTGGTTAC CATATTGCTA 
CTCCTGGCAT TTCTGTTCCT CATGCGGAAG GTTCAGGACT GCAGCCAGTG GAACGTGCTT 
CCCACTCAGT TCCTCTTCCT GCTGGCTGTG CTCGGGCTCT TCGGACTTAC TTTTGCCTTC 
ATCATCCAAC TCAACCATCA AACTGCCCCT GTTCGCTACT TCCTCTTTGG GGTTCTCTTT 
GCTATCTGCT TCTCCTGCCT CCTGGCTCAT GCCTCCAACC TGGTGAAGCT GGTCCGGGGT 
AGAGTCTCCT TCTGCTGGAC AACAATTCTG TTCATTGCTA TCGGTGTCAG CCTGTTGCAG 
ACCATCATTG CGATAGAGTA TGTGACCCTC ATCATGACCA GAGGCTTGAT GTTCGAGCAT 
ATGACACCGT ATCAGCTCAA TGTGGACTTT GTCTGTCTCC TGATCTATGT CCTCTTCCTG 
ATGGCCCTCA CTTTCTTCGT CTCCAAGGCC ACCTTCTGTG GCCCATGTGA GAACTGGAAA 
CAGCACGGAA GGCTCATATT TGCTACTGTG CTGGTCTCTA TCATTATCTG GGTGGTGTGG 
ATCTCCATGC TCTTGAGAGG CAACCCCCAG CTCCAGCGAC AGCCCCACTG GGACGATGCA 
GTCATCTGCA TTGGCCTGGT CACCAACGCT TGGGTCTTCC TGCTGATCTA CATCATCCCT 
GAGCTGAGCA TACTCTACAG GTCATGTAGG CAGGAGTGTC CTACACAAGG CAACGTCTGC 
CAGGTCCCTG TCTACCAACG CAGCTTCAGG ATGGATACCC AGGAACCCAC CAGAGCCCGA 
GACAGTGATG GAGCTCAGGA GGATGTAGCA CTAACTGCAT ATGGTACTCC CATTCAGCTG 
CAGAGTGCTG ATCCCAGCCG GGAGTATCTC ATCCCATCAG CTACACTAAG CCCACAGCAA 
GATGCAGGAT TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gpr158 mediates osteocalcin's regulation of cognition.
The Journal of experimental medicine214(10)2859-2873(2017 Oct)
Khrimian L,Obri A,Ramos-Brossier M,Rousseaud A,Moriceau S,Nicot AS,Mera P,Kosmidis S,Karnavas T,Saudou F,Gao XB,Oury F,Kandel E,Karsenty G

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Normal lung development in RAIG1-deficient mice despite unique lung epithelium-specific expression.
American journal of respiratory cell and molecular biology32(5)381-7(2005 May)
Xu J,Tian J,Shapiro SD

The RAIG family member, GPRC5D, is associated with hard-keratinized structures.
The Journal of investigative dermatology122(3)565-73(2004 Mar)
Inoue S,Nambu T,Shimomura T

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Gprc5d cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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