Htra3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Htra3
Entrez Gene ID	78558
Full Name	HtrA serine peptidase 3
Synonyms	2210021K23Rik,9530081K03Rik,Prsp,Tasp
General protein information	Preferred Names HtrA serine peptidase 3 Names serine protease HTRA3 high-temperature requirement factor A3 pregnancy-related serine protease probable serine protease HTRA3 toll-associated serine protease
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 B3

mRNA and Protein(s)

mRNA	Protein	Name
XM_030254908.1	XP_030110768.1	serine protease HTRA3 isoform X3
XM_011240796.2	XP_011239098.1	serine protease HTRA3 isoform X2
NM_001042615.2	NP_001036080.1	serine protease HTRA3 isoform b precursor
NM_030127.3	NP_084403.2	serine protease HTRA3 isoform a precursor
XM_006504186.1	XP_006504249.1	serine protease HTRA3 isoform X1
XM_011240796.3	XP_011239098.1	serine protease HTRA3 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	HTRA3	XP_005618790.1
Mus musculus (house mouse)	Htra3	NP_084403.2
Gallus gallus (chicken)	HTRA3	XP_420813.3
Homo sapiens (human)	HTRA3	NP_444272.1
Pan troglodytes (chimpanzee)	HTRA3	XP_517597.3
	HTRA3	XP_002804039.1
Bos taurus (cattle)	HTRA3	XP_002688528.2
Rattus norvegicus (Norway rat)	Htra3	NP_001257956.1
Danio rerio (zebrafish)	LOC573378	XP_692974.6
Xenopus tropicalis (tropical clawed frog)	htra3	XP_002938688.1

Gene Ontology
Bibliography

Related articles in PubMed

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood.
Li Y, Salamonsen LA, Hyett J, Costa FDS, Nie G
Scientific reports7(1)4627(2017 Jul)

Abnormal development of placenta in HtrA1-deficient mice.
Hasan MZ, Ikawati M, Tocharus J, Kawaichi M, Oka C
Developmental biology397(1)89-102(2015 Jan)

Transcriptomic analysis of mouse limb tendon cells during development.
Havis E, Bonnin MA, Olivera-Martinez I, Nazaret N, Ruggiu M, Weibel J, Durand C, Guerquin MJ, Bonod-Bidaud C, Ruggiero F, Schweitzer R, Duprez D
Development (Cambridge, England)141(19)3683-96(2014 Oct)

High-temperature requirement factor A3 (Htra3): a novel serine protease and its potential role in ovarian function and ovarian cancers.
Bowden MA, Drummond AE, Fuller PJ, Salamonsen LA, Findlay JK, Nie G
Molecular and cellular endocrinology327(1-2)13-8(2010 Oct)

HtrA3, a serine protease possessing an IGF-binding domain, is selectively expressed at the maternal-fetal interface during placentation in the mouse.
Nie G, Li Y, He H, Findlay JK, Salamonsen LA
Placenta27(4-5)491-501(2006 Apr-May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both mRNA and protein of HtrA3 were localized specifically in the maternal decidua. Only the maternal decidual cells, but not blood vessels or uterine NK cells that are present in large numbers, were positive for HtrA3.
Title: HtrA3, a serine protease possessing an IGF-binding domain, is selectively expressed at the maternal-fetal interface during placentation in the mouse.

Plays an important role in the formation/function of the placenta.
Title: A novel serine protease of the mammalian HtrA family is up-regulated in mouse uterus coinciding with placentation.

The following Htra3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Htra3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu00939	NM_001042615.2 Latest version!	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu07954	NM_030127.3 Latest version!	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$272.30 $389.00
OMu35258	XM_006504186.1 Latest version!	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu71718	XM_011240796.3 Latest version!	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu89042	XM_030254908.1 Latest version!	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu71718	XM_011240796.2	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Htra3 ( NM_001042615.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001036080.1 Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant 2, mRNA.

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CloneID	OMu00939
Clone ID Related Accession (Same CDS sequence)	NM_001042615.2
Accession Version	NM_001042615.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	serine protease HTRA3 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035194.1, AY156509.1, AK008764.1 and AI481644.1. On Nov 5, 2013 this sequence version replaced NM_001042615.1. Transcript Variant: This variant (2) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform b which is shorter and has a distinct C-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AY280664.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGCGC GCGCGCTGCT CCCCGCCACG CTGGCCATTC TGGCCACGCT GGCTGTGTTG 
GCTCTGGCCC GGGAGCCCCC AGCGGCTCCG TGTCCTGCGC GCTGCGACGT GTCGCGCTGT 
CCGAGCCCTC GCTGCCCTGG GGGCTATGTG CCTGACCTCT GCAACTGCTG CCTGGTGTGC 
GCTGCCAGCG AGGGCGAGCC CTGCGGCCGC CCCCTGGACT CTCCGTGCGG GGACAGTCTG 
GAGTGCGTGC GCGGCGTGTG CCGCTGCCGT TGGACCCACA CTGTGTGTGG CACAGACGGG 
CATACTTATG CCGACGTGTG CGCGCTGCAG GCCGCCAGCC GTCGTGCGTT GCAGGTCTCC 
GGGACTCCAG TGCGCCAGCT GCAGAAGGGT GCCTGTCCCT CTGGTCTCCA CCAGCTGACC 
AGTCCGCGGT ACAAGTTCAA CTTCATCGCC GATGTGGTGG AGAAGATTGC GCCAGCTGTG 
GTCCACATAG AGCTCTTTCT GAGACACCCC CTGTTTGGCC GGAATGTGCC GCTGTCCAGT 
GGCTCGGGCT TCATCATGTC AGAAGCCGGT TTGATCGTCA CCAACGCCCA CGTGGTCTCC 
AGCTCCAGCA CTGCCTCCGG CCGGCAGCAG CTGAAGGTGC AGCTGCAGAA TGGGGATGCC 
TATGAGGCCA CCATCCAGGA CATCGACAAG AAGTCGGACA TTGCCACGAT TGTAATCCAC 
CCCAAGAAAA AGCTCCCTGT GTTGCTGCTG GGTCACTCAG CAGACCTGCG GCCTGGCGAG 
TTCGTGGTGG CCATCGGCAG CCCCTTTGCC CTGCAGAACA CCGTGACAAC GGGCATTGTC 
AGCACTGCCC AGCGGGATGG CAAGGAGCTG GGTCTCCGGG ACTCAGACAT GGACTATATC 
CAGACCGATG CCATCATCAA TTACGGGAAC TCAGGAGGAC CCCTGGTGAA CCTGGATGGC 
GAGGTCATCG GCATCAACAC GCTCAAGGTT GCAGCTGGCA TCTCCTTTGC CATCCCCTCA 
GATCGCATCA CACGCTTCCT CTCTGAGTTC CAAAACAAGC ATGTGAAAGC CCTCTCACCA 
GCACTGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036080.1
CDS	435..1526
Translation	MQARALLPATLAILATLAVLALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQVSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKALSPALH

Target ORF information:

RefSeq Version	NM_001042615.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042615.2

ORF Insert Sequence:

ATGCAGGCGC GCGCGCTGCT CCCCGCCACG CTGGCCATTC TGGCCACGCT GGCTGTGTTG 
GCTCTGGCCC GGGAGCCCCC AGCGGCTCCG TGTCCTGCGC GCTGCGACGT GTCGCGCTGT 
CCGAGCCCTC GCTGCCCTGG GGGCTATGTG CCTGACCTCT GCAACTGCTG CCTGGTGTGC 
GCTGCCAGCG AGGGCGAGCC CTGCGGCCGC CCCCTGGACT CTCCGTGCGG GGACAGTCTG 
GAGTGCGTGC GCGGCGTGTG CCGCTGCCGT TGGACCCACA CTGTGTGTGG CACAGACGGG 
CATACTTATG CCGACGTGTG CGCGCTGCAG GCCGCCAGCC GTCGTGCGTT GCAGGTCTCC 
GGGACTCCAG TGCGCCAGCT GCAGAAGGGT GCCTGTCCCT CTGGTCTCCA CCAGCTGACC 
AGTCCGCGGT ACAAGTTCAA CTTCATCGCC GATGTGGTGG AGAAGATTGC GCCAGCTGTG 
GTCCACATAG AGCTCTTTCT GAGACACCCC CTGTTTGGCC GGAATGTGCC GCTGTCCAGT 
GGCTCGGGCT TCATCATGTC AGAAGCCGGT TTGATCGTCA CCAACGCCCA CGTGGTCTCC 
AGCTCCAGCA CTGCCTCCGG CCGGCAGCAG CTGAAGGTGC AGCTGCAGAA TGGGGATGCC 
TATGAGGCCA CCATCCAGGA CATCGACAAG AAGTCGGACA TTGCCACGAT TGTAATCCAC 
CCCAAGAAAA AGCTCCCTGT GTTGCTGCTG GGTCACTCAG CAGACCTGCG GCCTGGCGAG 
TTCGTGGTGG CCATCGGCAG CCCCTTTGCC CTGCAGAACA CCGTGACAAC GGGCATTGTC 
AGCACTGCCC AGCGGGATGG CAAGGAGCTG GGTCTCCGGG ACTCAGACAT GGACTATATC 
CAGACCGATG CCATCATCAA TTACGGGAAC TCAGGAGGAC CCCTGGTGAA CCTGGATGGC 
GAGGTCATCG GCATCAACAC GCTCAAGGTT GCAGCTGGCA TCTCCTTTGC CATCCCCTCA 
GATCGCATCA CACGCTTCCT CTCTGAGTTC CAAAACAAGC ATGTGAAAGC CCTCTCACCA 
GCACTGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htra3 ( NM_030127.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084403.2 Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu07954
Clone ID Related Accession (Same CDS sequence)	NM_030127.3
Accession Version	NM_030127.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	serine protease HTRA3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035194.1, AK020653.1, AK008764.1 and AY156509.1. On Nov 5, 2013 this sequence version replaced NM_030127.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: AY156509.1, AK035194.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGCGC GCGCGCTGCT CCCCGCCACG CTGGCCATTC TGGCCACGCT GGCTGTGTTG 
GCTCTGGCCC GGGAGCCCCC AGCGGCTCCG TGTCCTGCGC GCTGCGACGT GTCGCGCTGT 
CCGAGCCCTC GCTGCCCTGG GGGCTATGTG CCTGACCTCT GCAACTGCTG CCTGGTGTGC 
GCTGCCAGCG AGGGCGAGCC CTGCGGCCGC CCCCTGGACT CTCCGTGCGG GGACAGTCTG 
GAGTGCGTGC GCGGCGTGTG CCGCTGCCGT TGGACCCACA CTGTGTGTGG CACAGACGGG 
CATACTTATG CCGACGTGTG CGCGCTGCAG GCCGCCAGCC GTCGTGCGTT GCAGGTCTCC 
GGGACTCCAG TGCGCCAGCT GCAGAAGGGT GCCTGTCCCT CTGGTCTCCA CCAGCTGACC 
AGTCCGCGGT ACAAGTTCAA CTTCATCGCC GATGTGGTGG AGAAGATTGC GCCAGCTGTG 
GTCCACATAG AGCTCTTTCT GAGACACCCC CTGTTTGGCC GGAATGTGCC GCTGTCCAGT 
GGCTCGGGCT TCATCATGTC AGAAGCCGGT TTGATCGTCA CCAACGCCCA CGTGGTCTCC 
AGCTCCAGCA CTGCCTCCGG CCGGCAGCAG CTGAAGGTGC AGCTGCAGAA TGGGGATGCC 
TATGAGGCCA CCATCCAGGA CATCGACAAG AAGTCGGACA TTGCCACGAT TGTAATCCAC 
CCCAAGAAAA AGCTCCCTGT GTTGCTGCTG GGTCACTCAG CAGACCTGCG GCCTGGCGAG 
TTCGTGGTGG CCATCGGCAG CCCCTTTGCC CTGCAGAACA CCGTGACAAC GGGCATTGTC 
AGCACTGCCC AGCGGGATGG CAAGGAGCTG GGTCTCCGGG ACTCAGACAT GGACTATATC 
CAGACCGATG CCATCATCAA TTACGGGAAC TCAGGAGGAC CCCTGGTGAA CCTGGATGGC 
GAGGTCATCG GCATCAACAC GCTCAAGGTT GCAGCTGGCA TCTCCTTTGC CATCCCCTCA 
GATCGCATCA CACGCTTCCT CTCTGAGTTC CAAAACAAGC ATGTGAAAGA CTGGAAGAAG 
CGCTTCATTG GCATCCGGAT GCGGACCATC ACGCCAAGTT TGGTGGAGGA ACTGAAGGCC 
GCCAACCCAG ACTTTCCAGC GGTCAGCAGT GGAATATATG TTCAAGAGGT GGTTCCCAAT 
TCACCTTCTC AGAGAGGAGG CATCCAAGAT GGCGACATCA TCGTCAAAGT CAATGGCCGC 
CCCCTGGCGG ATTCCAGCGA GCTGCAGGAG GCAGTCCTGA ACGAGTCTTC ACTCCTGCTG 
GAGGTGCGGC GAGGCAATGA TGATCTCCTC TTCAGCATCA TCCCTGAGGT GGTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084403.2
CDS	435..1814
Translation	MQARALLPATLAILATLAVLALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQVSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM

Target ORF information:

RefSeq Version	NM_030127.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030127.3

ORF Insert Sequence:

ATGCAGGCGC GCGCGCTGCT CCCCGCCACG CTGGCCATTC TGGCCACGCT GGCTGTGTTG 
GCTCTGGCCC GGGAGCCCCC AGCGGCTCCG TGTCCTGCGC GCTGCGACGT GTCGCGCTGT 
CCGAGCCCTC GCTGCCCTGG GGGCTATGTG CCTGACCTCT GCAACTGCTG CCTGGTGTGC 
GCTGCCAGCG AGGGCGAGCC CTGCGGCCGC CCCCTGGACT CTCCGTGCGG GGACAGTCTG 
GAGTGCGTGC GCGGCGTGTG CCGCTGCCGT TGGACCCACA CTGTGTGTGG CACAGACGGG 
CATACTTATG CCGACGTGTG CGCGCTGCAG GCCGCCAGCC GTCGTGCGTT GCAGGTCTCC 
GGGACTCCAG TGCGCCAGCT GCAGAAGGGT GCCTGTCCCT CTGGTCTCCA CCAGCTGACC 
AGTCCGCGGT ACAAGTTCAA CTTCATCGCC GATGTGGTGG AGAAGATTGC GCCAGCTGTG 
GTCCACATAG AGCTCTTTCT GAGACACCCC CTGTTTGGCC GGAATGTGCC GCTGTCCAGT 
GGCTCGGGCT TCATCATGTC AGAAGCCGGT TTGATCGTCA CCAACGCCCA CGTGGTCTCC 
AGCTCCAGCA CTGCCTCCGG CCGGCAGCAG CTGAAGGTGC AGCTGCAGAA TGGGGATGCC 
TATGAGGCCA CCATCCAGGA CATCGACAAG AAGTCGGACA TTGCCACGAT TGTAATCCAC 
CCCAAGAAAA AGCTCCCTGT GTTGCTGCTG GGTCACTCAG CAGACCTGCG GCCTGGCGAG 
TTCGTGGTGG CCATCGGCAG CCCCTTTGCC CTGCAGAACA CCGTGACAAC GGGCATTGTC 
AGCACTGCCC AGCGGGATGG CAAGGAGCTG GGTCTCCGGG ACTCAGACAT GGACTATATC 
CAGACCGATG CCATCATCAA TTACGGGAAC TCAGGAGGAC CCCTGGTGAA CCTGGATGGC 
GAGGTCATCG GCATCAACAC GCTCAAGGTT GCAGCTGGCA TCTCCTTTGC CATCCCCTCA 
GATCGCATCA CACGCTTCCT CTCTGAGTTC CAAAACAAGC ATGTGAAAGA CTGGAAGAAG 
CGCTTCATTG GCATCCGGAT GCGGACCATC ACGCCAAGTT TGGTGGAGGA ACTGAAGGCC 
GCCAACCCAG ACTTTCCAGC GGTCAGCAGT GGAATATATG TTCAAGAGGT GGTTCCCAAT 
TCACCTTCTC AGAGAGGAGG CATCCAAGAT GGCGACATCA TCGTCAAAGT CAATGGCCGC 
CCCCTGGCGG ATTCCAGCGA GCTGCAGGAG GCAGTCCTGA ACGAGTCTTC ACTCCTGCTG 
GAGGTGCGGC GAGGCAATGA TGATCTCCTC TTCAGCATCA TCCCTGAGGT GGTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htra3 ( XM_006504186.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504249.1 Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu35258
Clone ID Related Accession (Same CDS sequence)	XM_006504186.1
Accession Version	XM_006504186.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	serine protease HTRA3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGCGC GCGCGCTGCT CCCCGCCACG CTGGCCATTC TGGCCACGCT GGCTGTGTTG 
GCTCTGGCCC GGGAGCCCCC AGCGGCTCCG TGTCCTGCGC GCTGCGACGT GTCGCGCTGT 
CCGAGCCCTC GCTGCCCTGG GGGCTATGTG CCTGACCTCT GCAACTGCTG CCTGGTGTGC 
GCTGCCAGCG AGGGCGAGCC CTGCGGCCGC CCCCTGGACT CTCCGTGCGG GGACAGTCTG 
GAGTGCGTGC GCGGCGTGTG CCGCTGCCGT TGGACCCACA CTGTGTGTGG CACAGACGGG 
CATACTTATG CCGACGTGTG CGCGCTGCAG GCCGCCAGCC GTCGTGCGTT GCAGGTCTCC 
GGGACTCCAG TGCGCCAGCT GCAGAAGGGT GCCTGTCCCT CTGGTCTCCA CCAGCTGACC 
AGTCCGCGGT ACAAGTTCAA CTTCATCGCC GATGTGGTGG AGAAGATTGC GCCAGCTGTG 
GTCCACATAG AGCTCTTTCT GAGACACCCC CTGTTTGGCC GGAATGTGCC GCTGTCCAGT 
GGCTCGGGCT TCATCATGTC AGAAGCCGGT TTGATCGTCA CCAACGCCCA CGTGGTCTCC 
AGCTCCAGCA CTGCCTCCGG CCGGCAGCAG CTGAAGGTGC AGCTGCAGAA TGGGGATGCC 
TATGAGGCCA CCATCCAGGA CATCGACAAG AAGTCGGACA TTGCCACGAT TGTAATCCAC 
CCCAAGAAAA AGCTCCCTGT GTTGCTGCTG GGTCACTCAG CAGACCTGCG GCCTGGCGAG 
TTCGTGGTGG CCATCGGCAG CCCCTTTGCC CTGCAGAACA CCGTGACAAC GGGCATTGTC 
AGCACTGCCC AGCGGGATGG CAAGGAGCTG GGTCTCCGGG ACTCAGACAT GGACTATATC 
CAGACCGATG CCATCATCAA TTACGGGAAC TCAGGAGGAC CCCTGGTGAA CCTGGATGGC 
GAGGTCATCG GCATCAACAC GCTCAAGGTT GCAGCTGGCA TCTCCTTTGC CATCCCCTCA 
GATCGCATCA CACGCTTCCT CTCTGAGTTC CAAAACAAGC ATGTGAAAGG TAAAGAACTC 
TCCCGAGGGG CAGACTGGAA GAAGCGCTTC ATTGGCATCC GGATGCGGAC CATCACGCCA 
AGTTTGGTGG AGGAACTGAA GGCCGCCAAC CCAGACTTTC CAGCGGTCAG CAGTGGAATA 
TATGTTCAAG AGGTGGTTCC CAATTCACCT TCTCAGAGAG GAGGCATCCA AGATGGCGAC 
ATCATCGTCA AAGTCAATGG CCGCCCCCTG GCGGATTCCA GCGAGCTGCA GGAGGCAGTC 
CTGAACGAGT CTTCACTCCT GCTGGAGGTG CGGCGAGGCA ATGATGATCT CCTCTTCAGC 
ATCATCCCTG AGGTGGTCAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504249.1
CDS	468..1871
Translation	MQARALLPATLAILATLAVLALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQVSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKGKELSRGADWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM

Target ORF information:

RefSeq Version	XM_006504186.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504186.1

ORF Insert Sequence:

ATGCAGGCGC GCGCGCTGCT CCCCGCCACG CTGGCCATTC TGGCCACGCT GGCTGTGTTG 
GCTCTGGCCC GGGAGCCCCC AGCGGCTCCG TGTCCTGCGC GCTGCGACGT GTCGCGCTGT 
CCGAGCCCTC GCTGCCCTGG GGGCTATGTG CCTGACCTCT GCAACTGCTG CCTGGTGTGC 
GCTGCCAGCG AGGGCGAGCC CTGCGGCCGC CCCCTGGACT CTCCGTGCGG GGACAGTCTG 
GAGTGCGTGC GCGGCGTGTG CCGCTGCCGT TGGACCCACA CTGTGTGTGG CACAGACGGG 
CATACTTATG CCGACGTGTG CGCGCTGCAG GCCGCCAGCC GTCGTGCGTT GCAGGTCTCC 
GGGACTCCAG TGCGCCAGCT GCAGAAGGGT GCCTGTCCCT CTGGTCTCCA CCAGCTGACC 
AGTCCGCGGT ACAAGTTCAA CTTCATCGCC GATGTGGTGG AGAAGATTGC GCCAGCTGTG 
GTCCACATAG AGCTCTTTCT GAGACACCCC CTGTTTGGCC GGAATGTGCC GCTGTCCAGT 
GGCTCGGGCT TCATCATGTC AGAAGCCGGT TTGATCGTCA CCAACGCCCA CGTGGTCTCC 
AGCTCCAGCA CTGCCTCCGG CCGGCAGCAG CTGAAGGTGC AGCTGCAGAA TGGGGATGCC 
TATGAGGCCA CCATCCAGGA CATCGACAAG AAGTCGGACA TTGCCACGAT TGTAATCCAC 
CCCAAGAAAA AGCTCCCTGT GTTGCTGCTG GGTCACTCAG CAGACCTGCG GCCTGGCGAG 
TTCGTGGTGG CCATCGGCAG CCCCTTTGCC CTGCAGAACA CCGTGACAAC GGGCATTGTC 
AGCACTGCCC AGCGGGATGG CAAGGAGCTG GGTCTCCGGG ACTCAGACAT GGACTATATC 
CAGACCGATG CCATCATCAA TTACGGGAAC TCAGGAGGAC CCCTGGTGAA CCTGGATGGC 
GAGGTCATCG GCATCAACAC GCTCAAGGTT GCAGCTGGCA TCTCCTTTGC CATCCCCTCA 
GATCGCATCA CACGCTTCCT CTCTGAGTTC CAAAACAAGC ATGTGAAAGG TAAAGAACTC 
TCCCGAGGGG CAGACTGGAA GAAGCGCTTC ATTGGCATCC GGATGCGGAC CATCACGCCA 
AGTTTGGTGG AGGAACTGAA GGCCGCCAAC CCAGACTTTC CAGCGGTCAG CAGTGGAATA 
TATGTTCAAG AGGTGGTTCC CAATTCACCT TCTCAGAGAG GAGGCATCCA AGATGGCGAC 
ATCATCGTCA AAGTCAATGG CCGCCCCCTG GCGGATTCCA GCGAGCTGCA GGAGGCAGTC 
CTGAACGAGT CTTCACTCCT GCTGGAGGTG CGGCGAGGCA ATGATGATCT CCTCTTCAGC 
ATCATCCCTG AGGTGGTCAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htra3 ( XM_011240796.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239098.1 Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X2, mRNA.

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CloneID	OMu71718
Clone ID Related Accession (Same CDS sequence)	XM_011240796.2 , XM_011240796.3
Accession Version	XM_011240796.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	serine protease HTRA3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240796.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGAAG CCGGTTTGAT CGTCACCAAC GCCCACGTGG TCTCCAGCTC CAGCACTGCC 
TCCGGCCGGC AGCAGCTGAA GGTGCAGCTG CAGAATGGGG ATGCCTATGA GGCCACCATC 
CAGGACATCG ACAAGAAGTC GGACATTGCC ACGATTGTAA TCCACCCCAA GAAAAAGCTC 
CCTGTGTTGC TGCTGGGTCA CTCAGCAGAC CTGCGGCCTG GCGAGTTCGT GGTGGCCATC 
GGCAGCCCCT TTGCCCTGCA GAACACCGTG ACAACGGGCA TTGTCAGCAC TGCCCAGCGG 
GATGGCAAGG AGCTGGGTCT CCGGGACTCA GACATGGACT ATATCCAGAC CGATGCCATC 
ATCAATTACG GGAACTCAGG AGGACCCCTG GTGAACCTGG ATGGCGAGGT CATCGGCATC 
AACACGCTCA AGGTTGCAGC TGGCATCTCC TTTGCCATCC CCTCAGATCG CATCACACGC 
TTCCTCTCTG AGTTCCAAAA CAAGCATGTG AAAGGTAAAG AACTCTCCCG AGGGGCAGAC 
TGGAAGAAGC GCTTCATTGG CATCCGGATG CGGACCATCA CGCCAAGTTT GGTGGAGGAA 
CTGAAGGCCG CCAACCCAGA CTTTCCAGCG GTCAGCAGTG GAATATATGT TCAAGAGGTG 
GTTCCCAATT CACCTTCTCA GAGAGGAGGC ATCCAAGATG GCGACATCAT CGTCAAAGTC 
AATGGCCGCC CCCTGGCGGA TTCCAGCGAG CTGCAGGAGG CAGTCCTGAA CGAGTCTTCA 
CTCCTGCTGG AGGTGCGGCG AGGCAATGAT GATCTCCTCT TCAGCATCAT CCCTGAGGTG 
GTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239098.1
CDS	516..1364
Translation	MSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKGKELSRGADWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM

Target ORF information:

RefSeq Version	XM_011240796.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240796.2

ORF Insert Sequence:

ATGTCAGAAG CCGGTTTGAT CGTCACCAAC GCCCACGTGG TCTCCAGCTC CAGCACTGCC 
TCCGGCCGGC AGCAGCTGAA GGTGCAGCTG CAGAATGGGG ATGCCTATGA GGCCACCATC 
CAGGACATCG ACAAGAAGTC GGACATTGCC ACGATTGTAA TCCACCCCAA GAAAAAGCTC 
CCTGTGTTGC TGCTGGGTCA CTCAGCAGAC CTGCGGCCTG GCGAGTTCGT GGTGGCCATC 
GGCAGCCCCT TTGCCCTGCA GAACACCGTG ACAACGGGCA TTGTCAGCAC TGCCCAGCGG 
GATGGCAAGG AGCTGGGTCT CCGGGACTCA GACATGGACT ATATCCAGAC CGATGCCATC 
ATCAATTACG GGAACTCAGG AGGACCCCTG GTGAACCTGG ATGGCGAGGT CATCGGCATC 
AACACGCTCA AGGTTGCAGC TGGCATCTCC TTTGCCATCC CCTCAGATCG CATCACACGC 
TTCCTCTCTG AGTTCCAAAA CAAGCATGTG AAAGGTAAAG AACTCTCCCG AGGGGCAGAC 
TGGAAGAAGC GCTTCATTGG CATCCGGATG CGGACCATCA CGCCAAGTTT GGTGGAGGAA 
CTGAAGGCCG CCAACCCAGA CTTTCCAGCG GTCAGCAGTG GAATATATGT TCAAGAGGTG 
GTTCCCAATT CACCTTCTCA GAGAGGAGGC ATCCAAGATG GCGACATCAT CGTCAAAGTC 
AATGGCCGCC CCCTGGCGGA TTCCAGCGAG CTGCAGGAGG CAGTCCTGAA CGAGTCTTCA 
CTCCTGCTGG AGGTGCGGCG AGGCAATGAT GATCTCCTCT TCAGCATCAT CCCTGAGGTG 
GTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htra3 ( XM_011240796.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239098.1 Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu71718
Clone ID Related Accession (Same CDS sequence)	XM_011240796.2 , XM_011240796.3
Accession Version	XM_011240796.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	serine protease HTRA3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011240796.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGAAG CCGGTTTGAT CGTCACCAAC GCCCACGTGG TCTCCAGCTC CAGCACTGCC 
TCCGGCCGGC AGCAGCTGAA GGTGCAGCTG CAGAATGGGG ATGCCTATGA GGCCACCATC 
CAGGACATCG ACAAGAAGTC GGACATTGCC ACGATTGTAA TCCACCCCAA GAAAAAGCTC 
CCTGTGTTGC TGCTGGGTCA CTCAGCAGAC CTGCGGCCTG GCGAGTTCGT GGTGGCCATC 
GGCAGCCCCT TTGCCCTGCA GAACACCGTG ACAACGGGCA TTGTCAGCAC TGCCCAGCGG 
GATGGCAAGG AGCTGGGTCT CCGGGACTCA GACATGGACT ATATCCAGAC CGATGCCATC 
ATCAATTACG GGAACTCAGG AGGACCCCTG GTGAACCTGG ATGGCGAGGT CATCGGCATC 
AACACGCTCA AGGTTGCAGC TGGCATCTCC TTTGCCATCC CCTCAGATCG CATCACACGC 
TTCCTCTCTG AGTTCCAAAA CAAGCATGTG AAAGGTAAAG AACTCTCCCG AGGGGCAGAC 
TGGAAGAAGC GCTTCATTGG CATCCGGATG CGGACCATCA CGCCAAGTTT GGTGGAGGAA 
CTGAAGGCCG CCAACCCAGA CTTTCCAGCG GTCAGCAGTG GAATATATGT TCAAGAGGTG 
GTTCCCAATT CACCTTCTCA GAGAGGAGGC ATCCAAGATG GCGACATCAT CGTCAAAGTC 
AATGGCCGCC CCCTGGCGGA TTCCAGCGAG CTGCAGGAGG CAGTCCTGAA CGAGTCTTCA 
CTCCTGCTGG AGGTGCGGCG AGGCAATGAT GATCTCCTCT TCAGCATCAT CCCTGAGGTG 
GTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239098.1
CDS	517..1365
Translation	MSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKGKELSRGADWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM

Target ORF information:

RefSeq Version	XM_011240796.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240796.3

ORF Insert Sequence:

ATGTCAGAAG CCGGTTTGAT CGTCACCAAC GCCCACGTGG TCTCCAGCTC CAGCACTGCC 
TCCGGCCGGC AGCAGCTGAA GGTGCAGCTG CAGAATGGGG ATGCCTATGA GGCCACCATC 
CAGGACATCG ACAAGAAGTC GGACATTGCC ACGATTGTAA TCCACCCCAA GAAAAAGCTC 
CCTGTGTTGC TGCTGGGTCA CTCAGCAGAC CTGCGGCCTG GCGAGTTCGT GGTGGCCATC 
GGCAGCCCCT TTGCCCTGCA GAACACCGTG ACAACGGGCA TTGTCAGCAC TGCCCAGCGG 
GATGGCAAGG AGCTGGGTCT CCGGGACTCA GACATGGACT ATATCCAGAC CGATGCCATC 
ATCAATTACG GGAACTCAGG AGGACCCCTG GTGAACCTGG ATGGCGAGGT CATCGGCATC 
AACACGCTCA AGGTTGCAGC TGGCATCTCC TTTGCCATCC CCTCAGATCG CATCACACGC 
TTCCTCTCTG AGTTCCAAAA CAAGCATGTG AAAGGTAAAG AACTCTCCCG AGGGGCAGAC 
TGGAAGAAGC GCTTCATTGG CATCCGGATG CGGACCATCA CGCCAAGTTT GGTGGAGGAA 
CTGAAGGCCG CCAACCCAGA CTTTCCAGCG GTCAGCAGTG GAATATATGT TCAAGAGGTG 
GTTCCCAATT CACCTTCTCA GAGAGGAGGC ATCCAAGATG GCGACATCAT CGTCAAAGTC 
AATGGCCGCC CCCTGGCGGA TTCCAGCGAG CTGCAGGAGG CAGTCCTGAA CGAGTCTTCA 
CTCCTGCTGG AGGTGCGGCG AGGCAATGAT GATCTCCTCT TCAGCATCAT CCCTGAGGTG 
GTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htra3 ( XM_030254908.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030110768.1 Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu89042
Clone ID Related Accession (Same CDS sequence)	XM_030254908.1
Accession Version	XM_030254908.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	serine protease HTRA3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGAAG CCGGTTTGAT CGTCACCAAC GCCCACGTGG TCTCCAGCTC CAGCACTGCC 
TCCGGCCGGC AGCAGCTGAA GGTGCAGCTG CAGAATGGGG ATGCCTATGA GGCCACCATC 
CAGGACATCG ACAAGAAGTC GGACATTGCC ACGATTGTAA TCCACCCCAA GAAAAAGCTC 
CCTGTGTTGC TGCTGGGTCA CTCAGCAGAC CTGCGGCCTG GCGAGTTCGT GGTGGCCATC 
GGCAGCCCCT TTGCCCTGCA GAACACCGTG ACAACGGGCA TTGTCAGCAC TGCCCAGCGG 
GATGGCAAGG AGCTGGGTCT CCGGGACTCA GACATGGACT ATATCCAGAC CGATGCCATC 
ATCAATTACG GGAACTCAGG AGGACCCCTG GTGAACCTGG ATGGCGAGGT CATCGGCATC 
AACACGCTCA AGGTTGCAGC TGGCATCTCC TTTGCCATCC CCTCAGATCG CATCACACGC 
TTCCTCTCTG AGTTCCAAAA CAAGCATGTG AAAGACTGGA AGAAGCGCTT CATTGGCATC 
CGGATGCGGA CCATCACGCC AAGTTTGGTG GAGGAACTGA AGGCCGCCAA CCCAGACTTT 
CCAGCGGTCA GCAGTGGAAT ATATGTTCAA GAGGTGGTTC CCAATTCACC TTCTCAGAGA 
GGAGGCATCC AAGATGGCGA CATCATCGTC AAAGTCAATG GCCGCCCCCT GGCGGATTCC 
AGCGAGCTGC AGGAGGCAGT CCTGAACGAG TCTTCACTCC TGCTGGAGGT GCGGCGAGGC 
AATGATGATC TCCTCTTCAG CATCATCCCT GAGGTGGTCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030110768.1
CDS	517..1341
Translation	MSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM

Target ORF information:

RefSeq Version	XM_030254908.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus HtrA serine peptidase 3 (Htra3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254908.1

ORF Insert Sequence:

ATGTCAGAAG CCGGTTTGAT CGTCACCAAC GCCCACGTGG TCTCCAGCTC CAGCACTGCC 
TCCGGCCGGC AGCAGCTGAA GGTGCAGCTG CAGAATGGGG ATGCCTATGA GGCCACCATC 
CAGGACATCG ACAAGAAGTC GGACATTGCC ACGATTGTAA TCCACCCCAA GAAAAAGCTC 
CCTGTGTTGC TGCTGGGTCA CTCAGCAGAC CTGCGGCCTG GCGAGTTCGT GGTGGCCATC 
GGCAGCCCCT TTGCCCTGCA GAACACCGTG ACAACGGGCA TTGTCAGCAC TGCCCAGCGG 
GATGGCAAGG AGCTGGGTCT CCGGGACTCA GACATGGACT ATATCCAGAC CGATGCCATC 
ATCAATTACG GGAACTCAGG AGGACCCCTG GTGAACCTGG ATGGCGAGGT CATCGGCATC 
AACACGCTCA AGGTTGCAGC TGGCATCTCC TTTGCCATCC CCTCAGATCG CATCACACGC 
TTCCTCTCTG AGTTCCAAAA CAAGCATGTG AAAGACTGGA AGAAGCGCTT CATTGGCATC 
CGGATGCGGA CCATCACGCC AAGTTTGGTG GAGGAACTGA AGGCCGCCAA CCCAGACTTT 
CCAGCGGTCA GCAGTGGAAT ATATGTTCAA GAGGTGGTTC CCAATTCACC TTCTCAGAGA 
GGAGGCATCC AAGATGGCGA CATCATCGTC AAAGTCAATG GCCGCCCCCT GGCGGATTCC 
AGCGAGCTGC AGGAGGCAGT CCTGAACGAG TCTTCACTCC TGCTGGAGGT GCGGCGAGGC 
AATGATGATC TCCTCTTCAG CATCATCCCT GAGGTGGTCA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood.
Scientific reports7(1)4627(2017 Jul)
Li Y,Salamonsen LA,Hyett J,Costa FDS,Nie G

Abnormal development of placenta in HtrA1-deficient mice.
Developmental biology397(1)89-102(2015 Jan)
Hasan MZ,Ikawati M,Tocharus J,Kawaichi M,Oka C

Transcriptomic analysis of mouse limb tendon cells during development.
Development (Cambridge, England)141(19)3683-96(2014 Oct)
Havis E,Bonnin MA,Olivera-Martinez I,Nazaret N,Ruggiu M,Weibel J,Durand C,Guerquin MJ,Bonod-Bidaud C,Ruggiero F,Schweitzer R,Duprez D

High-temperature requirement factor A3 (Htra3): a novel serine protease and its potential role in ovarian function and ovarian cancers.
Molecular and cellular endocrinology327(1-2)13-8(2010 Oct)
Bowden MA,Drummond AE,Fuller PJ,Salamonsen LA,Findlay JK,Nie G

HtrA3, a serine protease possessing an IGF-binding domain, is selectively expressed at the maternal-fetal interface during placentation in the mouse.
Placenta27(4-5)491-501(2006 Apr-May)
Nie G,Li Y,He H,Findlay JK,Salamonsen LA

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Htra3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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