Ticrr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ticrr
Entrez Gene ID	77011
Full Name	TOPBP1-interacting checkpoint and replication regulator
Synonyms	5730590G19Rik,BC028450,Lrrk1
General protein information	Preferred Names TOPBP1-interacting checkpoint and replication regulator Names treslin leucine-rich repeat kinase 1 topBP1-interacting, replication-stimulating protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 D2

mRNA and Protein(s)

mRNA	Protein	Name
NM_029835.1	NP_084111.1	treslin

Pathways from BioSystems

Homologies

	TICRR	XP_001093275.2
Bos taurus (cattle)	TICRR	XP_002696618.1
Mus musculus (house mouse)	Ticrr	NP_084111.1
Rattus norvegicus (Norway rat)	Ticrr	XP_218829.5
Gallus gallus (chicken)	C10H15ORF42	XP_413862.4
Homo sapiens (human)	TICRR	NP_689472.3
Pan troglodytes (chimpanzee)	TICRR	XP_003314917.2
Canis lupus familiaris (dog)	TICRR	XP_851592.2
Xenopus tropicalis (tropical clawed frog)	ticrr	XP_002944319.2

Gene Ontology
Bibliography

Related articles in PubMed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)

Regular treadmill exercise restores cardioprotective signaling pathways in obese mice independently from improvement in associated co-morbidities.
Pons S, Martin V, Portal L, Zini R, Morin D, Berdeaux A, Ghaleh B
Journal of molecular and cellular cardiology5482-9(2013 Jan)

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.
Sansam CL, Cruz NM, Danielian PS, Amsterdam A, Lau ML, Hopkins N, Lees JA
Genes & development24(2)183-94(2010 Jan)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Piao Y, Ko NT, Lim MK, Ko MS
Genome research11(9)1553-8(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ticrr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ticrr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22392	NM_029835.1 Latest version!	Mus musculus TOPBP1-interacting checkpoint and replication regulator (Ticrr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1392.30 $1989.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ticrr ( NM_029835.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084111.1 Mus musculus TOPBP1-interacting checkpoint and replication regulator (Ticrr), mRNA.

Price & Availability↑

CloneID	OMu22392
Clone ID Related Accession (Same CDS sequence)	NM_029835.1
Accession Version	NM_029835.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5670bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	treslin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY731867.1, AK041726.1, AK051639.1, CN537331.1, CF730550.1, AK033104.1, BC058634.1 and BC028450.1. On or before Dec 7, 2005 this sequence version replaced XM_620515.2, XM_920750.1, XM_908178.1. ##Evidence-Data-START## Transcript exon combination :: BC158103.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTGCT GTCACAAAGT GATGCTGCTG GTGGACACAG CGGGCGTCTC TGCTCCTCAT 
AGCCCGGCCC GACGCGCCGC CCTCCGGCTC CTCACTTACC TGAGCTGCCG CTTCGGCCTT 
GCCAGGGTCC ACTGGACCTT CAAGTTCTTC GACTCTCAGG GGGCACGGAG CCGGCCCTCC 
CGCGTGTCCG ACTTCCGCGA GCTGGGGAGC CGCTCCTGGG AGGACTTCGA GGAGGAGCTG 
GAGGCCAGGC TGGGGGATCG CCCTCCCGGA GCTCACCTGC CGGGCCCGAC GCCCAGAGCC 
ACCCACACGC ACGGTGCCCT GATGGAGACG CTGCTCGACT ACCAGTGGGA CCGGCCGGAG 
ATCACGTCGC CCACCAAGCC GATCCTGCGG AGTAGCGGCA GGAGGCTGCT GGACGCCGAC 
GGCGAGGCCA GGGAGGCCCA GGCCGCGCTC GGGGGCTTTG GGAACGCCGT CTTCCTCCTG 
GCGCCCTGTC CTCACTCGCA GAGGGAGCTG CTTCAGTTCG TGTCCGGGTG CGAGGCACAG 
GCTCAACGCG TGCCGCTCAC CCCCAAGCAG GTGATGGAGA AGGTGTTGCC CAAGAGAGTC 
CAAGAGGTTA TGATCGCCCG AAATATCACC TTGTACTGGG TGGACACCAC CGAGCGATCT 
AAGTTGTGGG CTTCCCCAGA CCATGTTGGA TACTGGACAG TGTGTGAGCT GCTACACCAT 
GGAGGAGGTA CCATCTTGCC AGCTGAAACT TGGAGCCTGG GATTTACTAA AGCCAGGGAA 
ACAGTGCTGC CATGTGGTGG CGAGCTGTCA CACAAACCTC ACCCCTCCCC GTGGATCTCA 
GCTCTGCCAA TAGATGCCAC TGTAAACTGT TTGCTGTATA ATTCTGAGTA TGAAGCCTCA 
TTTCCACGAA TTGAAGGAAC ATTATTTCTC CCTGTTCAAG GCAAAGAAAT TGAAGAAACA 
TGGGCAATCT CCCTGGAGCC TTTAGCCATG CATCAGAGAC ATTTTCAAAA GCCAGTCAGA 
ATTGTCCTAA GAGGCTCAGT GGCACAGTGG TCTCTCCCAG TGAGTAGTGC TTTAGGCACT 
GACAGTTGGA TGCTACAAAG TCCAGAGGAA CACAGGTCAA CTCAAAGGCT GTTGTTTCAG 
GAGCTGGTAA GCAGGCTGAC TGCTGAAGAA TTCCATCTGG TTGCCAGTGT GGATCCTGGT 
GAAGGCTGGC CCCCCATAAC GGGAATTATT TCCCCATTCT CTGCCAATGC CATGATTCTC 
ACAGTGTTCC GAGCCAAAGA AGCTGAATTT CAAAGCCATT TTCTCCAAAC AGCTGCGACT 
GAAGGTTCCC AGGATACAGC TTCCCTTTTC TCAGATGTTG TAGATAGTGT CCTGAATCAG 
AGTCATAATT TATTTGAAGA CCCTGCGTCT TCTGCCCCCT GTGTTCCAGA GTGGGTCCAG 
CAGGAGCTTA GTCATACCAG CTCCTGGAGT CCAGCTCTTG TCGAAAAGTG GTTTCCTTTC 
TCCAACGCCA GTGGTGCTAC TTCAGACTTG ATGGAATCAT TTTGGTTGTT ACACGCTGCC 
TCACCTGATA ATGATGAATC CTCCAAAACC GAAAGTGAAC TAACACGCTG CCTCTCTGAG 
CTCTACCAGA GATCTCACGA AGAATCTACT GTAGTCAATC AAGAACGCAG CAGAAAGAAA 
CGTGGTATCC CTCGAACTCC AGTGAGACAG AAGATGAATA CCATGTCCCG CTCCTTGAAG 
ATGTTGAATG TGGCAAGGCT AAATGTAAAG GCTCAGAAAT TACATCCAGA TGGTAGTCCA 
GACACGGCTG TAGAGAAAGG GCTCCAGAAA GCTGTCATTG GCAGAACAGC AGACAAATTG 
GAAGATAGAG GAAGGATATT AAGAAGTTCT AAACTTAAAG AATTTAAAAC CGAGGAGGAG 
CTTCTGGCTT ACATACATGA CAACTACCAA AAGGCTGTGG CTACGGAAGA AATCACATTG 
TATTCATGTG CACAAAATAT GGTCTCAACC ATTAAAATGT TCCTAAAATC AAAGGACATC 
AAGGAATTAG AAGTGGCCTG CCTGAGTCAT GTGAACAGTA ACCTCTTAAA AACCAGCAAG 
ACCCTTAGAC AGAACCTAGC CGGAAAGATG GATACAGAGG ACAAAGTCGG AGAGTGCCAG 
CTTCAGGTAT TTCTTCGTCT GGAGATGTGT GAGCAGTGCC CCTCAGTCCT GGACCGCCCA 
GATGAGGTGG AGCGCATAGT GGAGGAGGTG ACAGATTTGC TGCGTCTGGT GTGTCTCACT 
AAGGACTCAG CGTACCTGTC AGAGTTTCTG GAGGAGATCT TGAGATTGTA TATTGGCTCC 
ATCCCCGGGA CAATTGGACA ACTCTACCAC AGCCTGGGGT TAAAAATTCC TCAGAAGCTG 
GCTGGAGTCC TTCCTACAGG GTTTTTCAGT GATGATTCTA TGTCTCAAGA GAGCATGTCA 
CCACCTCCCT CATCAAGTAC TCACAGATCA GTGTCGGCCA TTACTGAGTC TGAGCAGCTG 
GAGGAGCTTC GGACCAGATC AGCCAAGAAG AGAAGGAAAA ATGCACTAAT AAGACATAAA 
AGTATTGCAG AGATTTCCCA GACTCTTCGA CAAATTGAAG TTCCCAAAGT GTCCAAGAGA 
GCTACAAGAA ATGAGAACTC CCACTCTGCT TCCATACAGC TGCCAGTCCC GAGGAAAGAC 
ACAATACAGG AAGTAACAAA AGTTCGAAGA AACCTCTTCA ACCAGGAAAT GCTTTCTCCT 
TCAAAGAGGG GGCTAAAGAA GGGGCTGCCT CGCAGCCATT CTGTATCTGC TTTGGAATGT 
CTCCACCATA AACAGGACAA GTTCAAGAAG ACCAAAAGCA GCACATTTCA GGGTTATTGC 
AAACTGCTGA CTAAGAGTGT GGCTGAGACC CCAGTCCACA AGCAAATCTC CAGGAGGCTG 
CTCCATAGAC AAATCAAGGG CAGGTCTTCT GATCCTGGTC CTGATATTCA TGTAGTTGAA 
GAGTCTCCTG AAAAAGAGGA TGAAATGACT TTGAGAAGAA GTCCTCGAAT CAAGCAGCTG 
TCATTTAGCA GAACGAACTC TGGCTCCTTC TATTCTGTAT CTCAGCCGAA ATCTCGAAGT 
GTGCAAAGAA TCCACTCGTC CCAGCAGGAG TCAGAACAAA GAGAAAATTT TCCAGTTCAA 
AGTATTCAGT CTCCTAAAAC ACTTCTTTTT GGGGCATTGT CTGAGATTCC CAGCTCCTCT 
AAGAAGGGTT CAGCCCAAAT TAAGAGATCC TTAAGAAGCA TGTTGGATTC TGAGATATCT 
ACATCTTACG AGACTCCCAA AAAGAGTAAC CAGAAATCTC CAAGCTTTTC TAAAACTACA 
CCAAGAAGAT TCCCTCGTAC AGCACAGACC TTACTATACA CTCCAGAAAG ACTACAAAAC 
TCCCCTACAG AAATGACATC AGCTGAAGGG ACCATTTCTG AAGCAACCAT AAAAACCCCC 
TCCTCACACG GTTACAACTC ACCATTTGCA TCAAAAGTCA CTTCTCAAAA GACAGTCTCC 
CCAGCAAAAG AAGAGACCTC TCCTCCCCTC ACAAAGCTAC CCAGCACACC CAGAGAGTCT 
GATGTCCAGC CACCTCAATG TTCGTCAGAC TGCACATGGC CACACTCAGT GAATTCCAGT 
CCAGAAGGTC CTTATTACCC AGCGTCCCCA CCTCCTATGG CTGGCCAGGC CAGGAGTCAG 
TGTCTGACCC CTATAAGATA CTCCTTCAGA ACCCCTCCAC GTACAGCCCT TGCTGGCACG 
TCTAAGCAGC AGGAGCACCA AGAGCTCCCT CTCCCCAGGG CCTCTCAGAC ACAAGAACCT 
CCACAGGGAC TGGAGAAGAA AGCTCTCAAA ATCCCAAAGA AACCAGCACA CACAAGTACT 
TCACCTCTTT CTCCAGAGGA ACATTATTCT GGATGTGATG TCTCCCCACA TCAACCTAGG 
AACTCTTTGT CAGCCTCCCC TCCTCCTGGA GAACTGAATT GGAAAGAACA CCAGACATCA 
CCCAGTGTAA CTTCATCTGT CTCTTGTCCT GTTCCTTCAA CTCCTCCTAG AACCCCACAG 
AGAATGACCT GCCCCATACC ACCTTCTCCA CCATCCAAGC TTCGGAGATC ATGTAGAAAG 
AAGTCCTGTC CTCCTCAGGA CTTCCCAGAG TGCCATCCTG GACCCTCTGC TGCTCCCGTG 
CTTAGCTCAG CCACCAGCCC AGGAGCTGTC ACAGGCTCTA GAGAGGAGCA GTCTCAGTTT 
TCTGAAGGAC AGAGTTACCT AGGCACTGGT TTCAGAAGTG ACTGTCATGT GTCCTCTCCT 
GTGCTCACTG CAAGTGACAC AAAGTGCTTG CCACTGATTG ATGAAGCCCA ACTCCATGGG 
CTTAAAAACC AAGAGGTAAA AAGTGGCATC TTGCCAGGGG AAGAAGGTGA GGAACCAGAG 
AGCACTATTG CCGACGAGCT TCCCTCTGTG TCTGACCCTG GGATTCTTGT ACCTGCGCCT 
TCCTCTGTGT CTAGCTCCTC TGAGCTGCTG CCCTACCCCC TGTGCTGTAC AGCAGACGGA 
AAGCAGAGGC AAGATGCTGC TCAGCAGGGG AGTCCACGAG CTTCCGAGGC CACCAGCAGC 
CCTCAGACCT ACGAAGTTGA GCTGGAGATG CAAGCTTCTG GCCTTCCCAA GCTCCGGATT 
AAAAAAATAG ACCCTGGAGT TCTTTTGGAA GCTGAGGCCC TAGGAAAGGA AGCCCCCCTG 
GGAGAGGAGG GTGCCCTCCC TGCTCTCTGT ATGCCCAAGG CCAGCAAGTC CTCCGGGAGA 
ACTGAGCACC CTTACTTGTC ACCCCCTTGT CTCCGCCCCT CACACAGCAC ACCTGGCAAG 
AATGGAGGTC AAACCTTCAT CTGCCAATCT TGTACTCCCT CTCGCTGTCC CCCCAGTACC 
CCCTCTCCAT TTCAAGCAGA TGCTGGGGTT TCTTGGACAC CATCCCCTAA GCAAAGTGGG 
AAGACCACTC CTGAAATTAT CAAAGACTGG CCCCGCAGGA AGAGGGCAGT GGATTGCAGT 
GCTGGACCCT CTGCTGGGAG AGGCGAGGCC AGTATGGACC TTCCTGGGTC CTTGTCACTG 
CTTGAGCCTG AGCCTGAGGG AAAGGAGCGA AGCCTTGAAC AAGACCTCTC TAAGGTTCTC 
ATCTCAGAGG AGTTTGAACT AGAGGGGGTG TGTCAGTTGC CAGACCAGTC ACCTCCCAAA 
GACAGTGCCT CTGTGACAGA GGAAACCTCC TGGGGACAGT TTGGATTAGG CAGAAAGAGA 
TTCCTGTCCG CCAAGGAAGA ATCTGAATAC AAAGTCAAAA GGGTCTGTGA TTCCCTGAGT 
GAGGATCCCC AAGCTAGCAA GCAGAAAGAG TGCTCTCCAC GCTGGAGTGC ACTACCACTC 
CACTCAGTAG GGGACGACGA GGTGTTTGTT TCTGGCTCCA CCCCACCCTC TGGTTGCATG 
GTTCGAAGCT GTCTCTCTGC CAGTGGTCTG CAGGCCTTGA CCCAGTCTCC ACTGCTGTTC 
CAAGGAAGAA CGCCCTCCTC TCATAGCACG GACACCAGAG ATGAGGAAGT GGATGTGTTC 
CCCTCTACTG CTGAAGAGTC TCCGTTCAGC CACACCCTCT CCCGGAAACG GCCTTTCAGA 
ACCTACACGA GAAAGAAGCT TATTAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084111.1
CDS	145..5814
Translation	MACCHKVMLLVDTAGVSAPHSPARRAALRLLTYLSCRFGLARVHWTFKFFDSQGARSRPSRVSDFRELGSRSWEDFEEELEARLGDRPPGAHLPGPTPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDADGEAREAQAALGGFGNAVFLLAPCPHSQRELLQFVSGCEAQAQRVPLTPKQVMEKVLPKRVQEVMIARNITLYWVDTTERSKLWASPDHVGYWTVCELLHHGGGTILPAETWSLGFTKARETVLPCGGELSHKPHPSPWISALPIDATVNCLLYNSEYEASFPRIEGTLFLPVQGKEIEETWAISLEPLAMHQRHFQKPVRIVLRGSVAQWSLPVSSALGTDSWMLQSPEEHRSTQRLLFQELVSRLTAEEFHLVASVDPGEGWPPITGIISPFSANAMILTVFRAKEAEFQSHFLQTAATEGSQDTASLFSDVVDSVLNQSHNLFEDPASSAPCVPEWVQQELSHTSSWSPALVEKWFPFSNASGATSDLMESFWLLHAASPDNDESSKTESELTRCLSELYQRSHEESTVVNQERSRKKRGIPRTPVRQKMNTMSRSLKMLNVARLNVKAQKLHPDGSPDTAVEKGLQKAVIGRTADKLEDRGRILRSSKLKEFKTEEELLAYIHDNYQKAVATEEITLYSCAQNMVSTIKMFLKSKDIKELEVACLSHVNSNLLKTSKTLRQNLAGKMDTEDKVGECQLQVFLRLEMCEQCPSVLDRPDEVERIVEEVTDLLRLVCLTKDSAYLSEFLEEILRLYIGSIPGTIGQLYHSLGLKIPQKLAGVLPTGFFSDDSMSQESMSPPPSSSTHRSVSAITESEQLEELRTRSAKKRRKNALIRHKSIAEISQTLRQIEVPKVSKRATRNENSHSASIQLPVPRKDTIQEVTKVRRNLFNQEMLSPSKRGLKKGLPRSHSVSALECLHHKQDKFKKTKSSTFQGYCKLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIHVVEESPEKEDEMTLRRSPRIKQLSFSRTNSGSFYSVSQPKSRSVQRIHSSQQESEQRENFPVQSIQSPKTLLFGALSEIPSSSKKGSAQIKRSLRSMLDSEISTSYETPKKSNQKSPSFSKTTPRRFPRTAQTLLYTPERLQNSPTEMTSAEGTISEATIKTPSSHGYNSPFASKVTSQKTVSPAKEETSPPLTKLPSTPRESDVQPPQCSSDCTWPHSVNSSPEGPYYPASPPPMAGQARSQCLTPIRYSFRTPPRTALAGTSKQQEHQELPLPRASQTQEPPQGLEKKALKIPKKPAHTSTSPLSPEEHYSGCDVSPHQPRNSLSASPPPGELNWKEHQTSPSVTSSVSCPVPSTPPRTPQRMTCPIPPSPPSKLRRSCRKKSCPPQDFPECHPGPSAAPVLSSATSPGAVTGSREEQSQFSEGQSYLGTGFRSDCHVSSPVLTASDTKCLPLIDEAQLHGLKNQEVKSGILPGEEGEEPESTIADELPSVSDPGILVPAPSSVSSSSELLPYPLCCTADGKQRQDAAQQGSPRASEATSSPQTYEVELEMQASGLPKLRIKKIDPGVLLEAEALGKEAPLGEEGALPALCMPKASKSSGRTEHPYLSPPCLRPSHSTPGKNGGQTFICQSCTPSRCPPSTPSPFQADAGVSWTPSPKQSGKTTPEIIKDWPRRKRAVDCSAGPSAGRGEASMDLPGSLSLLEPEPEGKERSLEQDLSKVLISEEFELEGVCQLPDQSPPKDSASVTEETSWGQFGLGRKRFLSAKEESEYKVKRVCDSLSEDPQASKQKECSPRWSALPLHSVGDDEVFVSGSTPPSGCMVRSCLSASGLQALTQSPLLFQGRTPSSHSTDTRDEEVDVFPSTAEESPFSHTLSRKRPFRTYTRKKLIS

Target ORF information:

RefSeq Version	NM_029835.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus TOPBP1-interacting checkpoint and replication regulator (Ticrr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029835.1

ORF Insert Sequence:

ATGGCCTGCT GTCACAAAGT GATGCTGCTG GTGGACACAG CGGGCGTCTC TGCTCCTCAT 
AGCCCGGCCC GACGCGCCGC CCTCCGGCTC CTCACTTACC TGAGCTGCCG CTTCGGCCTT 
GCCAGGGTCC ACTGGACCTT CAAGTTCTTC GACTCTCAGG GGGCACGGAG CCGGCCCTCC 
CGCGTGTCCG ACTTCCGCGA GCTGGGGAGC CGCTCCTGGG AGGACTTCGA GGAGGAGCTG 
GAGGCCAGGC TGGGGGATCG CCCTCCCGGA GCTCACCTGC CGGGCCCGAC GCCCAGAGCC 
ACCCACACGC ACGGTGCCCT GATGGAGACG CTGCTCGACT ACCAGTGGGA CCGGCCGGAG 
ATCACGTCGC CCACCAAGCC GATCCTGCGG AGTAGCGGCA GGAGGCTGCT GGACGCCGAC 
GGCGAGGCCA GGGAGGCCCA GGCCGCGCTC GGGGGCTTTG GGAACGCCGT CTTCCTCCTG 
GCGCCCTGTC CTCACTCGCA GAGGGAGCTG CTTCAGTTCG TGTCCGGGTG CGAGGCACAG 
GCTCAACGCG TGCCGCTCAC CCCCAAGCAG GTGATGGAGA AGGTGTTGCC CAAGAGAGTC 
CAAGAGGTTA TGATCGCCCG AAATATCACC TTGTACTGGG TGGACACCAC CGAGCGATCT 
AAGTTGTGGG CTTCCCCAGA CCATGTTGGA TACTGGACAG TGTGTGAGCT GCTACACCAT 
GGAGGAGGTA CCATCTTGCC AGCTGAAACT TGGAGCCTGG GATTTACTAA AGCCAGGGAA 
ACAGTGCTGC CATGTGGTGG CGAGCTGTCA CACAAACCTC ACCCCTCCCC GTGGATCTCA 
GCTCTGCCAA TAGATGCCAC TGTAAACTGT TTGCTGTATA ATTCTGAGTA TGAAGCCTCA 
TTTCCACGAA TTGAAGGAAC ATTATTTCTC CCTGTTCAAG GCAAAGAAAT TGAAGAAACA 
TGGGCAATCT CCCTGGAGCC TTTAGCCATG CATCAGAGAC ATTTTCAAAA GCCAGTCAGA 
ATTGTCCTAA GAGGCTCAGT GGCACAGTGG TCTCTCCCAG TGAGTAGTGC TTTAGGCACT 
GACAGTTGGA TGCTACAAAG TCCAGAGGAA CACAGGTCAA CTCAAAGGCT GTTGTTTCAG 
GAGCTGGTAA GCAGGCTGAC TGCTGAAGAA TTCCATCTGG TTGCCAGTGT GGATCCTGGT 
GAAGGCTGGC CCCCCATAAC GGGAATTATT TCCCCATTCT CTGCCAATGC CATGATTCTC 
ACAGTGTTCC GAGCCAAAGA AGCTGAATTT CAAAGCCATT TTCTCCAAAC AGCTGCGACT 
GAAGGTTCCC AGGATACAGC TTCCCTTTTC TCAGATGTTG TAGATAGTGT CCTGAATCAG 
AGTCATAATT TATTTGAAGA CCCTGCGTCT TCTGCCCCCT GTGTTCCAGA GTGGGTCCAG 
CAGGAGCTTA GTCATACCAG CTCCTGGAGT CCAGCTCTTG TCGAAAAGTG GTTTCCTTTC 
TCCAACGCCA GTGGTGCTAC TTCAGACTTG ATGGAATCAT TTTGGTTGTT ACACGCTGCC 
TCACCTGATA ATGATGAATC CTCCAAAACC GAAAGTGAAC TAACACGCTG CCTCTCTGAG 
CTCTACCAGA GATCTCACGA AGAATCTACT GTAGTCAATC AAGAACGCAG CAGAAAGAAA 
CGTGGTATCC CTCGAACTCC AGTGAGACAG AAGATGAATA CCATGTCCCG CTCCTTGAAG 
ATGTTGAATG TGGCAAGGCT AAATGTAAAG GCTCAGAAAT TACATCCAGA TGGTAGTCCA 
GACACGGCTG TAGAGAAAGG GCTCCAGAAA GCTGTCATTG GCAGAACAGC AGACAAATTG 
GAAGATAGAG GAAGGATATT AAGAAGTTCT AAACTTAAAG AATTTAAAAC CGAGGAGGAG 
CTTCTGGCTT ACATACATGA CAACTACCAA AAGGCTGTGG CTACGGAAGA AATCACATTG 
TATTCATGTG CACAAAATAT GGTCTCAACC ATTAAAATGT TCCTAAAATC AAAGGACATC 
AAGGAATTAG AAGTGGCCTG CCTGAGTCAT GTGAACAGTA ACCTCTTAAA AACCAGCAAG 
ACCCTTAGAC AGAACCTAGC CGGAAAGATG GATACAGAGG ACAAAGTCGG AGAGTGCCAG 
CTTCAGGTAT TTCTTCGTCT GGAGATGTGT GAGCAGTGCC CCTCAGTCCT GGACCGCCCA 
GATGAGGTGG AGCGCATAGT GGAGGAGGTG ACAGATTTGC TGCGTCTGGT GTGTCTCACT 
AAGGACTCAG CGTACCTGTC AGAGTTTCTG GAGGAGATCT TGAGATTGTA TATTGGCTCC 
ATCCCCGGGA CAATTGGACA ACTCTACCAC AGCCTGGGGT TAAAAATTCC TCAGAAGCTG 
GCTGGAGTCC TTCCTACAGG GTTTTTCAGT GATGATTCTA TGTCTCAAGA GAGCATGTCA 
CCACCTCCCT CATCAAGTAC TCACAGATCA GTGTCGGCCA TTACTGAGTC TGAGCAGCTG 
GAGGAGCTTC GGACCAGATC AGCCAAGAAG AGAAGGAAAA ATGCACTAAT AAGACATAAA 
AGTATTGCAG AGATTTCCCA GACTCTTCGA CAAATTGAAG TTCCCAAAGT GTCCAAGAGA 
GCTACAAGAA ATGAGAACTC CCACTCTGCT TCCATACAGC TGCCAGTCCC GAGGAAAGAC 
ACAATACAGG AAGTAACAAA AGTTCGAAGA AACCTCTTCA ACCAGGAAAT GCTTTCTCCT 
TCAAAGAGGG GGCTAAAGAA GGGGCTGCCT CGCAGCCATT CTGTATCTGC TTTGGAATGT 
CTCCACCATA AACAGGACAA GTTCAAGAAG ACCAAAAGCA GCACATTTCA GGGTTATTGC 
AAACTGCTGA CTAAGAGTGT GGCTGAGACC CCAGTCCACA AGCAAATCTC CAGGAGGCTG 
CTCCATAGAC AAATCAAGGG CAGGTCTTCT GATCCTGGTC CTGATATTCA TGTAGTTGAA 
GAGTCTCCTG AAAAAGAGGA TGAAATGACT TTGAGAAGAA GTCCTCGAAT CAAGCAGCTG 
TCATTTAGCA GAACGAACTC TGGCTCCTTC TATTCTGTAT CTCAGCCGAA ATCTCGAAGT 
GTGCAAAGAA TCCACTCGTC CCAGCAGGAG TCAGAACAAA GAGAAAATTT TCCAGTTCAA 
AGTATTCAGT CTCCTAAAAC ACTTCTTTTT GGGGCATTGT CTGAGATTCC CAGCTCCTCT 
AAGAAGGGTT CAGCCCAAAT TAAGAGATCC TTAAGAAGCA TGTTGGATTC TGAGATATCT 
ACATCTTACG AGACTCCCAA AAAGAGTAAC CAGAAATCTC CAAGCTTTTC TAAAACTACA 
CCAAGAAGAT TCCCTCGTAC AGCACAGACC TTACTATACA CTCCAGAAAG ACTACAAAAC 
TCCCCTACAG AAATGACATC AGCTGAAGGG ACCATTTCTG AAGCAACCAT AAAAACCCCC 
TCCTCACACG GTTACAACTC ACCATTTGCA TCAAAAGTCA CTTCTCAAAA GACAGTCTCC 
CCAGCAAAAG AAGAGACCTC TCCTCCCCTC ACAAAGCTAC CCAGCACACC CAGAGAGTCT 
GATGTCCAGC CACCTCAATG TTCGTCAGAC TGCACATGGC CACACTCAGT GAATTCCAGT 
CCAGAAGGTC CTTATTACCC AGCGTCCCCA CCTCCTATGG CTGGCCAGGC CAGGAGTCAG 
TGTCTGACCC CTATAAGATA CTCCTTCAGA ACCCCTCCAC GTACAGCCCT TGCTGGCACG 
TCTAAGCAGC AGGAGCACCA AGAGCTCCCT CTCCCCAGGG CCTCTCAGAC ACAAGAACCT 
CCACAGGGAC TGGAGAAGAA AGCTCTCAAA ATCCCAAAGA AACCAGCACA CACAAGTACT 
TCACCTCTTT CTCCAGAGGA ACATTATTCT GGATGTGATG TCTCCCCACA TCAACCTAGG 
AACTCTTTGT CAGCCTCCCC TCCTCCTGGA GAACTGAATT GGAAAGAACA CCAGACATCA 
CCCAGTGTAA CTTCATCTGT CTCTTGTCCT GTTCCTTCAA CTCCTCCTAG AACCCCACAG 
AGAATGACCT GCCCCATACC ACCTTCTCCA CCATCCAAGC TTCGGAGATC ATGTAGAAAG 
AAGTCCTGTC CTCCTCAGGA CTTCCCAGAG TGCCATCCTG GACCCTCTGC TGCTCCCGTG 
CTTAGCTCAG CCACCAGCCC AGGAGCTGTC ACAGGCTCTA GAGAGGAGCA GTCTCAGTTT 
TCTGAAGGAC AGAGTTACCT AGGCACTGGT TTCAGAAGTG ACTGTCATGT GTCCTCTCCT 
GTGCTCACTG CAAGTGACAC AAAGTGCTTG CCACTGATTG ATGAAGCCCA ACTCCATGGG 
CTTAAAAACC AAGAGGTAAA AAGTGGCATC TTGCCAGGGG AAGAAGGTGA GGAACCAGAG 
AGCACTATTG CCGACGAGCT TCCCTCTGTG TCTGACCCTG GGATTCTTGT ACCTGCGCCT 
TCCTCTGTGT CTAGCTCCTC TGAGCTGCTG CCCTACCCCC TGTGCTGTAC AGCAGACGGA 
AAGCAGAGGC AAGATGCTGC TCAGCAGGGG AGTCCACGAG CTTCCGAGGC CACCAGCAGC 
CCTCAGACCT ACGAAGTTGA GCTGGAGATG CAAGCTTCTG GCCTTCCCAA GCTCCGGATT 
AAAAAAATAG ACCCTGGAGT TCTTTTGGAA GCTGAGGCCC TAGGAAAGGA AGCCCCCCTG 
GGAGAGGAGG GTGCCCTCCC TGCTCTCTGT ATGCCCAAGG CCAGCAAGTC CTCCGGGAGA 
ACTGAGCACC CTTACTTGTC ACCCCCTTGT CTCCGCCCCT CACACAGCAC ACCTGGCAAG 
AATGGAGGTC AAACCTTCAT CTGCCAATCT TGTACTCCCT CTCGCTGTCC CCCCAGTACC 
CCCTCTCCAT TTCAAGCAGA TGCTGGGGTT TCTTGGACAC CATCCCCTAA GCAAAGTGGG 
AAGACCACTC CTGAAATTAT CAAAGACTGG CCCCGCAGGA AGAGGGCAGT GGATTGCAGT 
GCTGGACCCT CTGCTGGGAG AGGCGAGGCC AGTATGGACC TTCCTGGGTC CTTGTCACTG 
CTTGAGCCTG AGCCTGAGGG AAAGGAGCGA AGCCTTGAAC AAGACCTCTC TAAGGTTCTC 
ATCTCAGAGG AGTTTGAACT AGAGGGGGTG TGTCAGTTGC CAGACCAGTC ACCTCCCAAA 
GACAGTGCCT CTGTGACAGA GGAAACCTCC TGGGGACAGT TTGGATTAGG CAGAAAGAGA 
TTCCTGTCCG CCAAGGAAGA ATCTGAATAC AAAGTCAAAA GGGTCTGTGA TTCCCTGAGT 
GAGGATCCCC AAGCTAGCAA GCAGAAAGAG TGCTCTCCAC GCTGGAGTGC ACTACCACTC 
CACTCAGTAG GGGACGACGA GGTGTTTGTT TCTGGCTCCA CCCCACCCTC TGGTTGCATG 
GTTCGAAGCT GTCTCTCTGC CAGTGGTCTG CAGGCCTTGA CCCAGTCTCC ACTGCTGTTC 
CAAGGAAGAA CGCCCTCCTC TCATAGCACG GACACCAGAG ATGAGGAAGT GGATGTGTTC 
CCCTCTACTG CTGAAGAGTC TCCGTTCAGC CACACCCTCT CCCGGAAACG GCCTTTCAGA 
ACCTACACGA GAAAGAAGCT TATTAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Immunity43(4)690-702(2015 Oct)
Ray JP,Staron MM,Shyer JA,Ho PC,Marshall HD,Gray SM,Laidlaw BJ,Araki K,Ahmed R,Kaech SM,Craft J

Regular treadmill exercise restores cardioprotective signaling pathways in obese mice independently from improvement in associated co-morbidities.
Journal of molecular and cellular cardiology5482-9(2013 Jan)
Pons S,Martin V,Portal L,Zini R,Morin D,Berdeaux A,Ghaleh B

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.
Genes & development24(2)183-94(2010 Jan)
Sansam CL,Cruz NM,Danielian PS,Amsterdam A,Lau ML,Hopkins N,Lees JA

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Genome research11(9)1553-8(2001 Sep)
Piao Y,Ko NT,Lim MK,Ko MS

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Ticrr cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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