Urah cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Urah
Entrez Gene ID	76974
Full Name	urate (5-hydroxyiso-) hydrolase
Synonyms	1190003J15Rik,2810420C16Rik,HIUHase
General protein information	Preferred Names urate (5-hydroxyiso-) hydrolase Names 5-hydroxyisourate hydrolase HIU hydrolase transthyretin-related protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F4

mRNA and Protein(s)

mRNA	Protein	Name
NM_029821.2	NP_084097.1	5-hydroxyisourate hydrolase isoform 2
XM_030243093.1	XP_030098953.1	5-hydroxyisourate hydrolase isoform X2
NM_001347605.1	NP_001334534.1	5-hydroxyisourate hydrolase isoform 1
NM_001359805.1	NP_001346734.1	5-hydroxyisourate hydrolase isoform 2
NM_029821.3	NP_084097.1	5-hydroxyisourate hydrolase isoform 2
XM_006536273.1	XP_006536336.1	5-hydroxyisourate hydrolase isoform X2
XM_030243092.1	XP_030098952.1	5-hydroxyisourate hydrolase isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC740695	XP_001142852.3
	LOC715821	XP_001106222.2
Mus musculus (house mouse)	Urah	NP_084097.1
Danio rerio (zebrafish)	urah	NP_001038917.2
Danio rerio (zebrafish)	LOC570474	NP_001186950.1
Drosophila melanogaster (fruit fly)	CG30016	NP_724982.1
Rattus norvegicus (Norway rat)	RGD1309350	NP_001127979.1
Gallus gallus (chicken)	LOC415859	XP_004944387.1
Xenopus tropicalis (tropical clawed frog)	LOC100489904	XP_004913646.1
Caenorhabditis elegans (roundworm)	ZK697.8	NP_503496.2
Bos taurus (cattle)	LOC100296324	XP_002694914.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000415	XP_310683.3
Caenorhabditis elegans (roundworm)	R09H10.3	NP_001040980.1
Rattus norvegicus (Norway rat)	LOC100911028	XP_003749053.1

Gene Ontology
Bibliography

Related articles in PubMed

Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
Stevenson WS, Hyland CD, Zhang JG, Morgan PO, Willson TA, Gill A, Hilton AA, Viney EM, Bahlo M, Masters SL, Hennebry S, Richardson SJ, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS
Proceedings of the National Academy of Sciences of the United States of America107(38)16625-30(2010 Sep)

Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction.
Lee Y, Park BC, Lee DH, Bae KH, Cho S, Lee CH, Lee JS, Myung PK, Park SG
Molecules and cells22(2)141-5(2006 Oct)

Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes.
Ramazzina I, Folli C, Secchi A, Berni R, Percudani R
Nature chemical biology2(3)144-8(2006 Mar)

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.
Nishimura M, Yokoi N, Miki T, Horikawa Y, Yoshioka H, Takeda J, Ohara O, Seino S
DNA research : an international journal for rapid publication of reports on genes and genomes11(5)315-23(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Substitution of cysteine for tyrosine in a conserved helical region of HIU hydrolase resulted in undetectable protein expression. Homozygotes for the mutation had elevated platelet counts secondary to excess thrombopoietin production and hepatomegaly.
Title: Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.

Study provides evidence that mouse transthyretin-related protein facilitates the hydrolysis of 5-hydroxyisourate, the end product of the uricase reaction.
Title: Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction.

Identified as the gene encoding the enzyme catalyzing the second step of the pathway from uric acid to S-allantoin.
Title: Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes.

The following Urah gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Urah cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu40117	NM_001347605.1 Latest version!	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu07527	NM_001359805.1 Latest version!	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu07527	NM_029821.3 Latest version!	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu07527	XM_030243093.1 Latest version!	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu07527	XM_006536273.1 Latest version!	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu89661	XM_030243092.1 Latest version!	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu07527	NM_029821.2	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Urah ( NM_001347605.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334534.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu40117
Clone ID Related Accession (Same CDS sequence)	NM_001347605.1
Accession Version	NM_001347605.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 426bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC107815.11. On Dec 2, 2016 this sequence version replaced XM_006536272.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BF532294.1, CA456945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTTCCA GGACCGCCCC GCGGCTGATG ACGCTCCAGA GACACTTAGG CTGGCCGCAG 
GCTGGCAACA TGGCTACCGA GAGCAGTCCC CTGACTACTC ACGTTCTAGA CACTGCCTCA 
GGGCTCCCTG CCCAAGGCCT CTGCCTCCGG CTGTCCCGCC TGGAGGCCCC CTGCCAGCAG 
TGGATGGAGC TGAGGACAAG CTACACAAAC CTGGACGGTC GCTGTCCTGG GCTCCTGACA 
CCAAGCCAGA TAAAGCCAGG CACCTATAAG CTGTTCTTCG ACACAGAGCG CTACTGGAAA 
GAGCGGGGTC AAGAGAGCTT TTACCCCTAT GTAGAGGTGG TTTTCACTAT TACAAAGGAG 
ACCCAGAAGT TCCACGTACC TCTGCTGCTG AGCCCATGGT CCTACACCAC CTACCGGGGG 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334534.1
CDS	62..487
Translation	MSSRTAPRLMTLQRHLGWPQAGNMATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS

Target ORF information:

RefSeq Version	NM_001347605.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347605.1

ORF Insert Sequence:

ATGAGTTCCA GGACCGCCCC GCGGCTGATG ACGCTCCAGA GACACTTAGG CTGGCCGCAG 
GCTGGCAACA TGGCTACCGA GAGCAGTCCC CTGACTACTC ACGTTCTAGA CACTGCCTCA 
GGGCTCCCTG CCCAAGGCCT CTGCCTCCGG CTGTCCCGCC TGGAGGCCCC CTGCCAGCAG 
TGGATGGAGC TGAGGACAAG CTACACAAAC CTGGACGGTC GCTGTCCTGG GCTCCTGACA 
CCAAGCCAGA TAAAGCCAGG CACCTATAAG CTGTTCTTCG ACACAGAGCG CTACTGGAAA 
GAGCGGGGTC AAGAGAGCTT TTACCCCTAT GTAGAGGTGG TTTTCACTAT TACAAAGGAG 
ACCCAGAAGT TCCACGTACC TCTGCTGCTG AGCCCATGGT CCTACACCAC CTACCGGGGG 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Urah ( NM_029821.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084097.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu07527
Clone ID Related Accession (Same CDS sequence)	NM_029821.2 , XM_030243093.1 , NM_001359805.1 , NM_029821.3 , XM_006536273.1
Accession Version	NM_029821.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-28
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK013117.1. On Apr 6, 2007 this sequence version replaced NM_029821.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK013117.1, BY704695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084097.1
CDS	126..482
Translation	MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS

Target ORF information:

RefSeq Version	NM_029821.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029821.2

ORF Insert Sequence:

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Urah ( NM_001359805.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001346734.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu07527
Clone ID Related Accession (Same CDS sequence)	NM_029821.2 , XM_030243093.1 , NM_001359805.1 , NM_029821.3 , XM_006536273.1
Accession Version	NM_001359805.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK004470.1, AA510160.1, AC107815.11 and BP776625.1. On Jan 13, 2018 this sequence version replaced XM_006536273.1. ##Evidence-Data-START## Transcript exon combination :: BF181073.1, BI648914.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001346734.1
CDS	134..490
Translation	MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS

Target ORF information:

RefSeq Version	NM_001359805.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001359805.1

ORF Insert Sequence:

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Urah ( NM_029821.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084097.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu07527
Clone ID Related Accession (Same CDS sequence)	NM_029821.2 , XM_030243093.1 , NM_001359805.1 , NM_029821.3 , XM_006536273.1
Accession Version	NM_029821.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK004470.1, BY145477.1, AK013117.1 and BP776625.1. On Jan 13, 2018 this sequence version replaced NM_029821.2. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BY704695.1, AK004470.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084097.1
CDS	343..699
Translation	MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS

Target ORF information:

RefSeq Version	NM_029821.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029821.3

ORF Insert Sequence:

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Urah ( XM_030243093.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030098953.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu07527
Clone ID Related Accession (Same CDS sequence)	NM_029821.2 , XM_030243093.1 , NM_001359805.1 , NM_029821.3 , XM_006536273.1
Accession Version	XM_030243093.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030098953.1
CDS	36..392
Translation	MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS

Target ORF information:

RefSeq Version	XM_030243093.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030243093.1

ORF Insert Sequence:

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Urah ( XM_006536273.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536336.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu07527
Clone ID Related Accession (Same CDS sequence)	NM_029821.2 , XM_030243093.1 , NM_001359805.1 , NM_029821.3 , XM_006536273.1
Accession Version	XM_006536273.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536336.1
CDS	115..471
Translation	MATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS

Target ORF information:

RefSeq Version	XM_006536273.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536273.1

ORF Insert Sequence:

ATGGCTACCG AGAGCAGTCC CCTGACTACT CACGTTCTAG ACACTGCCTC AGGGCTCCCT 
GCCCAAGGCC TCTGCCTCCG GCTGTCCCGC CTGGAGGCCC CCTGCCAGCA GTGGATGGAG 
CTGAGGACAA GCTACACAAA CCTGGACGGT CGCTGTCCTG GGCTCCTGAC ACCAAGCCAG 
ATAAAGCCAG GCACCTATAA GCTGTTCTTC GACACAGAGC GCTACTGGAA AGAGCGGGGT 
CAAGAGAGCT TTTACCCCTA TGTAGAGGTG GTTTTCACTA TTACAAAGGA GACCCAGAAG 
TTCCACGTAC CTCTGCTGCT GAGCCCATGG TCCTACACCA CCTACCGGGG GAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Urah ( XM_030243092.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030098952.1 Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X1, mRNA.

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CloneID	OMu89661
Clone ID Related Accession (Same CDS sequence)	XM_030243092.1
Accession Version	XM_030243092.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	5-hydroxyisourate hydrolase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCCA GGACCGCCCC GCGGCTGATG ACGCTCCAGA GACACTTAGG CTGGCCGCAG 
GCTGGCAACA TGGCTACCGA GAGCAGTCCC CTGACTACTC ACGTTCTAGA CACTGCCTCA 
GGGCTCCCTG CCCAAGGCCT CTGCCTCCGG CTGTCCCGCC TGGAGGCCCC CTGCCAGCAG 
TGGATGGAGC TGAGGACAAG CTACACAAAC CTGGACGGTC GCTGTCCTGG GCTCCTGACA 
CCAAGCCAGA TAAAGCCAGG CACCTATAAG CTGTTCTTCG ACACAGAGCG CTACTGGAAA 
GAGCGGGGTC AAGAGAGCTT TTACCCCTAT GTAGAGCCGG CATGGCACCT GACCTCCTGC 
TGTCTGGAAG ACCCAGGGGC TATTGCAGGA AGGACTCACC ATCTTCAGTG TCTTCAAGAA 
CCTTCTCTGC TTCTCACAGG TGGTTTTCAC TATTACAAAG GAGACCCAGA AGTTCCACGT 
ACCTCTGCTG CTGAGCCCAT GGTCCTACAC CACCTACCGG GGGAGTTAAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030098952.1
CDS	242..775
Translation	MSSRTAPRLMTLQRHLGWPQAGNMATESSPLTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYKLFFDTERYWKERGQESFYPYVEPAWHLTSCCLEDPGAIAGRTHHLQCLQEPSLLLTGGFHYYKGDPEVPRTSAAEPMVLHHLPGELK

Target ORF information:

RefSeq Version	XM_030243092.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus urate (5-hydroxyiso-) hydrolase (Urah), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030243092.1

ORF Insert Sequence:

ATGAGTTCCA GGACCGCCCC GCGGCTGATG ACGCTCCAGA GACACTTAGG CTGGCCGCAG 
GCTGGCAACA TGGCTACCGA GAGCAGTCCC CTGACTACTC ACGTTCTAGA CACTGCCTCA 
GGGCTCCCTG CCCAAGGCCT CTGCCTCCGG CTGTCCCGCC TGGAGGCCCC CTGCCAGCAG 
TGGATGGAGC TGAGGACAAG CTACACAAAC CTGGACGGTC GCTGTCCTGG GCTCCTGACA 
CCAAGCCAGA TAAAGCCAGG CACCTATAAG CTGTTCTTCG ACACAGAGCG CTACTGGAAA 
GAGCGGGGTC AAGAGAGCTT TTACCCCTAT GTAGAGCCGG CATGGCACCT GACCTCCTGC 
TGTCTGGAAG ACCCAGGGGC TATTGCAGGA AGGACTCACC ATCTTCAGTG TCTTCAAGAA 
CCTTCTCTGC TTCTCACAGG TGGTTTTCAC TATTACAAAG GAGACCCAGA AGTTCCACGT 
ACCTCTGCTG CTGAGCCCAT GGTCCTACAC CACCTACCGG GGGAGTTAAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
Proceedings of the National Academy of Sciences of the United States of America107(38)16625-30(2010 Sep)
Stevenson WS,Hyland CD,Zhang JG,Morgan PO,Willson TA,Gill A,Hilton AA,Viney EM,Bahlo M,Masters SL,Hennebry S,Richardson SJ,Nicola NA,Metcalf D,Hilton DJ,Roberts AW,Alexander WS

Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction.
Molecules and cells22(2)141-5(2006 Oct)
Lee Y,Park BC,Lee DH,Bae KH,Cho S,Lee CH,Lee JS,Myung PK,Park SG

Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes.
Nature chemical biology2(3)144-8(2006 Mar)
Ramazzina I,Folli C,Secchi A,Berni R,Percudani R

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.
DNA research : an international journal for rapid publication of reports on genes and genomes11(5)315-23(2004 Oct)
Nishimura M,Yokoi N,Miki T,Horikawa Y,Yoshioka H,Takeda J,Ohara O,Seino S

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Urah cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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電話

FAX

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