Bcl2l12 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bcl2l12
Entrez Gene ID	75736
Full Name	BCL2-like 12 (proline rich)
Synonyms	2810475P17Rik,5430429M05Rik,Bcl-L12,Bcl2-L12
General protein information	Preferred Names BCL2-like 12 (proline rich) Names bcl-2-like protein 12
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 B3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006541267.4	XP_006541330.1	bcl-2-like protein 12 isoform X1
XM_006541267.3	XP_006541330.1	bcl-2-like protein 12 isoform X1
NM_029410.3	NP_083686.1	bcl-2-like protein 12

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	BCL2L12	XP_005616916.1
Rattus norvegicus (Norway rat)	Bcl2l12	NP_001101950.1
Homo sapiens (human)	BCL2L12	NP_619580.1
Mus musculus (house mouse)	Bcl2l12	NP_083686.1
Bos taurus (cattle)	BCL2L12	NP_001094618.1
Pan troglodytes (chimpanzee)	BCL2L12	XP_512827.2

Gene Ontology
Bibliography

Related articles in PubMed

Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System.
Proenca-Modena JL, Hyde JL, Sesti-Costa R, Lucas T, Pinto AK, Richner JM, Gorman MJ, Lazear HM, Diamond MS
Journal of virology90(1)189-205(2015 Oct)

Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING.
Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T, Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, Takubo K
Cell reports11(1)71-84(2015 Apr)

Effective and lesion-free cutaneous influenza vaccination.
Wang J, Li B, Wu MX
Proceedings of the National Academy of Sciences of the United States of America112(16)5005-10(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

nuclear Bcl2L12 physically and functionally interacts with the p53 tumor suppressor
Title: Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor.

Data show that apoptotic defect in Irf3(-/-)Bcl2l12(-/-) MEFs was rescued by the ectopic expression of Bcl2L12, but not IRF3.
Title: Cell type-dependent proapoptotic role of Bcl2L12 revealed by a mutation concomitant with the disruption of the juxtaposed Irf3 gene.

The following Bcl2l12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bcl2l12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu21764	NM_029410.3 Latest version!	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu39094	XM_006541267.4 Latest version!	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu39094	XM_006541267.3	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bcl2l12 ( NM_029410.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083686.1 Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), mRNA.

Price & Availability↑

CloneID	OMu21764
Clone ID Related Accession (Same CDS sequence)	NM_029410.3
Accession Version	NM_029410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 12
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK017362.1 and BQ031795.1. On Dec 8, 2009 this sequence version replaced NM_029410.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK017362.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGCT CTGAAGAGTT GGGTCTCCGA GAGGACACAC TGAAGGTTCT GACGGCCTTC 
CTTAAGCGCG GTGAAGTCGC TGGGTCCCCT GTCCCAACTC CACCCAGGAG TCCTGCCCAA 
GAGGAGACAA CAGATTTCCT GAGCCGCCTC CGAAGATGCC TCCCTTGTCC CCTGGGGAGA 
GGAGCTCCCC CCACGGAGTC CTCTAGGCCC CACTTCCTTC CCCTCCGCCC CTGCTATGGT 
TCCGAGCCTG GCCCAGCCTC TTCCGAGTTC TATGCCCTGG TTGCCCAGCG GCTGGAACAA 
TTGGTGCAGG AGCAACTGAA GTCCCCGCCC AGTTCAGAGT TCCAGGGACC CCCACCCACG 
GAGAAGGAAG CCCTGCTAAG GCGGCTGGTA GCCTTGCTGG AGGAAGAGGC AGAAGTCATC 
AACCAAAAGC TGGCATCTGA CCCGGCTCTG CATCGTAAAC TGGCCCGCCT GTCCGCAGGC 
TCTTTCGCCC GCCTTGTGGA ACTCTTCTCT AGCCGGGAAA GCAGCTCCTC CCCAAATTGC 
TCCAGCCCGT CTCTGCCGTG CCCGGGGCCC CCACCGCCAT CCCCGGATCC TCTGGCACGC 
CTGGCACTAG CCATGGAATT GAGCCGGCGT GTGGCTGGGC TTGGGGGTCC CCTGGCCAAC 
CTCAGTGTTG AGCATGTACA CAGCTTCCTG CCTTGGGTCC AGGCCCATGG GGGATGGGCA 
GGCATCCTGG CCTCCTCACC TGTGGACTTG AACTTGCCCT TGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083686.1
CDS	126..893
Translation	MAGSEELGLREDTLKVLTAFLKRGEVAGSPVPTPPRSPAQEETTDFLSRLRRCLPCPLGRGAPPTESSRPHFLPLRPCYGSEPGPASSEFYALVAQRLEQLVQEQLKSPPSSEFQGPPPTEKEALLRRLVALLEEEAEVINQKLASDPALHRKLARLSAGSFARLVELFSSRESSSSPNCSSPSLPCPGPPPPSPDPLARLALAMELSRRVAGLGGPLANLSVEHVHSFLPWVQAHGGWAGILASSPVDLNLPLD

Target ORF information:

RefSeq Version	NM_029410.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029410.3

ORF Insert Sequence:

ATGGCCGGCT CTGAAGAGTT GGGTCTCCGA GAGGACACAC TGAAGGTTCT GACGGCCTTC 
CTTAAGCGCG GTGAAGTCGC TGGGTCCCCT GTCCCAACTC CACCCAGGAG TCCTGCCCAA 
GAGGAGACAA CAGATTTCCT GAGCCGCCTC CGAAGATGCC TCCCTTGTCC CCTGGGGAGA 
GGAGCTCCCC CCACGGAGTC CTCTAGGCCC CACTTCCTTC CCCTCCGCCC CTGCTATGGT 
TCCGAGCCTG GCCCAGCCTC TTCCGAGTTC TATGCCCTGG TTGCCCAGCG GCTGGAACAA 
TTGGTGCAGG AGCAACTGAA GTCCCCGCCC AGTTCAGAGT TCCAGGGACC CCCACCCACG 
GAGAAGGAAG CCCTGCTAAG GCGGCTGGTA GCCTTGCTGG AGGAAGAGGC AGAAGTCATC 
AACCAAAAGC TGGCATCTGA CCCGGCTCTG CATCGTAAAC TGGCCCGCCT GTCCGCAGGC 
TCTTTCGCCC GCCTTGTGGA ACTCTTCTCT AGCCGGGAAA GCAGCTCCTC CCCAAATTGC 
TCCAGCCCGT CTCTGCCGTG CCCGGGGCCC CCACCGCCAT CCCCGGATCC TCTGGCACGC 
CTGGCACTAG CCATGGAATT GAGCCGGCGT GTGGCTGGGC TTGGGGGTCC CCTGGCCAAC 
CTCAGTGTTG AGCATGTACA CAGCTTCCTG CCTTGGGTCC AGGCCCATGG GGGATGGGCA 
GGCATCCTGG CCTCCTCACC TGTGGACTTG AACTTGCCCT TGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bcl2l12 ( XM_006541267.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006541330.1 Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu39094
Clone ID Related Accession (Same CDS sequence)	XM_006541267.4 , XM_006541267.3
Accession Version	XM_006541267.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006541267.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGCT CTGAAGAGTT GGGTCTCCGA GAGGACACAC TGAAGGTTCT GACGGCCTTC 
CTTAAGCGCG GTGAAGTCGC TGGGTCCCCT GTCCCAACTC CACCCAGGAG TCCTGCCCAA 
GAGGAGACAA CAGATTTCCT GAGCCGCCTC CGAAGATGCC TCCCTTGTCC CCTGGGGAGA 
GGAGCTCCCC CCACGGAGTC CTCTAGGCCC CACTTCCTTC CCCTCCGCCC CTGCTATGGT 
TCCGAGCCTG GCCCAGCCTC TTCCGAGTTC TATGCCCTGG TTGCCCAGCG GCTGGAACAA 
TTGGTGCAGG AGCAACTGAA GTCCCCGCCC AGTTCAGAGT TCCAGGGACC CCCACCCACG 
GAGAAGGAAG CCCTGCTAAG GCGGCTGGTA GCCTTGCTGG AGGAAGAGGC AGAAGTCATC 
AACCAAAAGT TAAACACTGA AAAACAAAGG ACAGCAAACA AAAGAAGAGG CCAGAACCAA 
GAGCCAGCTG GCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006541330.1
CDS	185..682
Translation	MAGSEELGLREDTLKVLTAFLKRGEVAGSPVPTPPRSPAQEETTDFLSRLRRCLPCPLGRGAPPTESSRPHFLPLRPCYGSEPGPASSEFYALVAQRLEQLVQEQLKSPPSSEFQGPPPTEKEALLRRLVALLEEEAEVINQKLNTEKQRTANKRRGQNQEPAGI

Target ORF information:

RefSeq Version	XM_006541267.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006541267.3

ORF Insert Sequence:

ATGGCCGGCT CTGAAGAGTT GGGTCTCCGA GAGGACACAC TGAAGGTTCT GACGGCCTTC 
CTTAAGCGCG GTGAAGTCGC TGGGTCCCCT GTCCCAACTC CACCCAGGAG TCCTGCCCAA 
GAGGAGACAA CAGATTTCCT GAGCCGCCTC CGAAGATGCC TCCCTTGTCC CCTGGGGAGA 
GGAGCTCCCC CCACGGAGTC CTCTAGGCCC CACTTCCTTC CCCTCCGCCC CTGCTATGGT 
TCCGAGCCTG GCCCAGCCTC TTCCGAGTTC TATGCCCTGG TTGCCCAGCG GCTGGAACAA 
TTGGTGCAGG AGCAACTGAA GTCCCCGCCC AGTTCAGAGT TCCAGGGACC CCCACCCACG 
GAGAAGGAAG CCCTGCTAAG GCGGCTGGTA GCCTTGCTGG AGGAAGAGGC AGAAGTCATC 
AACCAAAAGT TAAACACTGA AAAACAAAGG ACAGCAAACA AAAGAAGAGG CCAGAACCAA 
GAGCCAGCTG GCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bcl2l12 ( XM_006541267.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006541330.1 Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu39094
Clone ID Related Accession (Same CDS sequence)	XM_006541267.4 , XM_006541267.3
Accession Version	XM_006541267.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	bcl-2-like protein 12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006541267.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGCT CTGAAGAGTT GGGTCTCCGA GAGGACACAC TGAAGGTTCT GACGGCCTTC 
CTTAAGCGCG GTGAAGTCGC TGGGTCCCCT GTCCCAACTC CACCCAGGAG TCCTGCCCAA 
GAGGAGACAA CAGATTTCCT GAGCCGCCTC CGAAGATGCC TCCCTTGTCC CCTGGGGAGA 
GGAGCTCCCC CCACGGAGTC CTCTAGGCCC CACTTCCTTC CCCTCCGCCC CTGCTATGGT 
TCCGAGCCTG GCCCAGCCTC TTCCGAGTTC TATGCCCTGG TTGCCCAGCG GCTGGAACAA 
TTGGTGCAGG AGCAACTGAA GTCCCCGCCC AGTTCAGAGT TCCAGGGACC CCCACCCACG 
GAGAAGGAAG CCCTGCTAAG GCGGCTGGTA GCCTTGCTGG AGGAAGAGGC AGAAGTCATC 
AACCAAAAGT TAAACACTGA AAAACAAAGG ACAGCAAACA AAAGAAGAGG CCAGAACCAA 
GAGCCAGCTG GCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006541330.1
CDS	185..682
Translation	MAGSEELGLREDTLKVLTAFLKRGEVAGSPVPTPPRSPAQEETTDFLSRLRRCLPCPLGRGAPPTESSRPHFLPLRPCYGSEPGPASSEFYALVAQRLEQLVQEQLKSPPSSEFQGPPPTEKEALLRRLVALLEEEAEVINQKLNTEKQRTANKRRGQNQEPAGI

Target ORF information:

RefSeq Version	XM_006541267.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006541267.4

ORF Insert Sequence:

ATGGCCGGCT CTGAAGAGTT GGGTCTCCGA GAGGACACAC TGAAGGTTCT GACGGCCTTC 
CTTAAGCGCG GTGAAGTCGC TGGGTCCCCT GTCCCAACTC CACCCAGGAG TCCTGCCCAA 
GAGGAGACAA CAGATTTCCT GAGCCGCCTC CGAAGATGCC TCCCTTGTCC CCTGGGGAGA 
GGAGCTCCCC CCACGGAGTC CTCTAGGCCC CACTTCCTTC CCCTCCGCCC CTGCTATGGT 
TCCGAGCCTG GCCCAGCCTC TTCCGAGTTC TATGCCCTGG TTGCCCAGCG GCTGGAACAA 
TTGGTGCAGG AGCAACTGAA GTCCCCGCCC AGTTCAGAGT TCCAGGGACC CCCACCCACG 
GAGAAGGAAG CCCTGCTAAG GCGGCTGGTA GCCTTGCTGG AGGAAGAGGC AGAAGTCATC 
AACCAAAAGT TAAACACTGA AAAACAAAGG ACAGCAAACA AAAGAAGAGG CCAGAACCAA 
GAGCCAGCTG GCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System.
Journal of virology90(1)189-205(2015 Oct)
Proenca-Modena JL,Hyde JL,Sesti-Costa R,Lucas T,Pinto AK,Richner JM,Gorman MJ,Lazear HM,Diamond MS

Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING.
Cell reports11(1)71-84(2015 Apr)
Kobayashi H,Kobayashi CI,Nakamura-Ishizu A,Karigane D,Haeno H,Yamamoto KN,Sato T,Ohteki T,Hayakawa Y,Barber GN,Kurokawa M,Suda T,Takubo K

Effective and lesion-free cutaneous influenza vaccination.
Proceedings of the National Academy of Sciences of the United States of America112(16)5005-10(2015 Apr)
Wang J,Li B,Wu MX

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Bcl2l12 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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