Slamf8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slamf8
Entrez Gene ID	74748
Full Name	SLAM family member 8
Synonyms	5830408F06Rik,Blame,SBBI42
General protein information	Preferred Names SLAM family member 8 Names SLAM family member 8 B lymphocyte activator macrophage expressed
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 H3

mRNA and Protein(s)

mRNA	Protein	Name
XM_030243230.1	XP_030099090.1	SLAM family member 8 isoform X1
NM_029084.3	NP_083360.2	SLAM family member 8 precursor
XM_006497009.2	XP_006497072.1	SLAM family member 8 isoform X1
XM_006497009.3	XP_006497072.1	SLAM family member 8 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLAMF8	XP_513918.2
Mus musculus (house mouse)	Slamf8	NP_083360.2
Homo sapiens (human)	SLAMF8	NP_064510.1
Bos taurus (cattle)	SLAMF8	NP_001192723.1
	SLAMF8	XP_001117299.1
Rattus norvegicus (Norway rat)	Slamf8	NP_001099443.1

Gene Ontology
Bibliography

Related articles in PubMed

Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8.
Wang G, van Driel BJ, Liao G, O'Keeffe MS, Halibozek PJ, Flipse J, Yigit B, Azcutia V, Luscinskas FW, Wang N, Terhorst C
PloS one10(3)e0121968(2015)

SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.
De Calisto J, Wang N, Wang G, Yigit B, Engel P, Terhorst C
Frontiers in immunology5186(2014)

Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages.
Wang G, Abad?a-Molina AC, Berger SB, Romero X, O'Keeffe MS, Rojas-Barros DI, Aleman M, Liao G, Maganto-Garc?a E, Fresno M, Wang N, Detre C, Terhorst C
Journal of immunology (Baltimore, Md. : 1950)188(12)5829-32(2012 Jun)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

Cloning, expression, and function of BLAME, a novel member of the CD2 family.
Kingsbury GA, Feeney LA, Nong Y, Calandra SA, Murphy CJ, Corcoran JM, Wang Y, Prabhu Das MR, Busfield SJ, Fraser CC, Villeval JL
Journal of immunology (Baltimore, Md. : 1950)166(9)5675-80(2001 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Slamf1 and Slamf8 govern ROS-dependent innate immune responses of myeloid cells.
Title: Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8.

Slamf8 was found to be a negative regulator of Nox2 activity in bacterial phagosomes.
Title: Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages.

The following Slamf8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slamf8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06509	NM_029084.3 Latest version!	Mus musculus SLAM family member 8 (Slamf8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu28855	XM_006497009.3 Latest version!	Mus musculus SLAM family member 8 (Slamf8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu85275	XM_030243230.1 Latest version!	Mus musculus SLAM family member 8 (Slamf8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu28855	XM_006497009.2	Mus musculus SLAM family member 8 (Slamf8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slamf8 ( NM_029084.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083360.2 Mus musculus SLAM family member 8 (Slamf8), mRNA.

Price & Availability↑

CloneID	OMu06509
Clone ID Related Accession (Same CDS sequence)	NM_029084.3
Accession Version	NM_029084.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	SLAM family member 8 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK142633.1. On Apr 6, 2007 this sequence version replaced NM_029084.2. ##Evidence-Data-START## Transcript exon combination :: AK142633.1, BC024587.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGTGGTCCC TCTGGAGTCT TCTTCTCTTT GAAGCTCTCC TTCCCGTTGT GGTTGTCAGT 
GTCCAAGTGC TAAGCAAGGT AGGGGACTCA GAGCTGCTGG TGGCCGAGTG TCCTCCGGGC 
TTCCAAGTGC GTGAGGCTAT CTGGCGATCT CTGTGGCCAT CGGAGGAGCT CCTGGCCACA 
TTTTTCCGAG GTTCCTTGGA GACTCTGTAC CACTCTCGTT TCCTGGGCCG AGTCCAGCTA 
TATGACAACC TCAGCCTGGA GCTTGGACCC CTGAAACCTG GAGACAGCGG CAATTTCTCT 
GTGCTGATGG TGGATACAAG GGGTCAAACC TGGACCCAGA CCCTGTATCT CAAGGTGTAC 
GATGCAGTAC CCAAGCCCGA GGTTCAAGTG TTCACTGCTG CAGCAGAGGA GACCCAACCC 
CTCAATACCT GTCAGGTCTT CTTGTCCTGC TGGGCCCCCA ACATCAGTGA CATAACCTAC 
AGCTGGCGAC GGGAGGGGAC AGTGGACTTC AATGGTGAAG TGCACAGCCA TTTCTCAAAT 
GGACAGGTGT TAAGTGTCTC ACTGGGACTG GGGGACAAGG ATGTGGCCTT TACCTGCATT 
GCCTCCAATC CTGTCAGCTG GGATATGACC ACAGTCACCC CCTGGGAGAG CTGCCATCAC 
GAGGCAGCCT CCGGGAAGGC CTCCTACAAG GACGTGCTAC TGGTAGTAGT GCCAATTACA 
CTGTTCCTGA TCCTGGCTGG TCTCTTTGGG GCATGGCACC ATGGCCTCTG CTCAGGGAAG 
AAGAAGGATG CTTGCACTGA CGGGGTGCTT CCAGAGACAG AGAATGCCCT CGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083360.2
CDS	137..973
Translation	MWSLWSLLLFEALLPVVVVSVQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTRGQTWTQTLYLKVYDAVPKPEVQVFTAAAEETQPLNTCQVFLSCWAPNISDITYSWRREGTVDFNGEVHSHFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASGKASYKDVLLVVVPITLFLILAGLFGAWHHGLCSGKKKDACTDGVLPETENALV

Target ORF information:

RefSeq Version	NM_029084.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus SLAM family member 8 (Slamf8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029084.3

ORF Insert Sequence:

ATGTGGTCCC TCTGGAGTCT TCTTCTCTTT GAAGCTCTCC TTCCCGTTGT GGTTGTCAGT 
GTCCAAGTGC TAAGCAAGGT AGGGGACTCA GAGCTGCTGG TGGCCGAGTG TCCTCCGGGC 
TTCCAAGTGC GTGAGGCTAT CTGGCGATCT CTGTGGCCAT CGGAGGAGCT CCTGGCCACA 
TTTTTCCGAG GTTCCTTGGA GACTCTGTAC CACTCTCGTT TCCTGGGCCG AGTCCAGCTA 
TATGACAACC TCAGCCTGGA GCTTGGACCC CTGAAACCTG GAGACAGCGG CAATTTCTCT 
GTGCTGATGG TGGATACAAG GGGTCAAACC TGGACCCAGA CCCTGTATCT CAAGGTGTAC 
GATGCAGTAC CCAAGCCCGA GGTTCAAGTG TTCACTGCTG CAGCAGAGGA GACCCAACCC 
CTCAATACCT GTCAGGTCTT CTTGTCCTGC TGGGCCCCCA ACATCAGTGA CATAACCTAC 
AGCTGGCGAC GGGAGGGGAC AGTGGACTTC AATGGTGAAG TGCACAGCCA TTTCTCAAAT 
GGACAGGTGT TAAGTGTCTC ACTGGGACTG GGGGACAAGG ATGTGGCCTT TACCTGCATT 
GCCTCCAATC CTGTCAGCTG GGATATGACC ACAGTCACCC CCTGGGAGAG CTGCCATCAC 
GAGGCAGCCT CCGGGAAGGC CTCCTACAAG GACGTGCTAC TGGTAGTAGT GCCAATTACA 
CTGTTCCTGA TCCTGGCTGG TCTCTTTGGG GCATGGCACC ATGGCCTCTG CTCAGGGAAG 
AAGAAGGATG CTTGCACTGA CGGGGTGCTT CCAGAGACAG AGAATGCCCT CGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slamf8 ( XM_006497009.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497072.1 Mus musculus SLAM family member 8 (Slamf8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu28855
Clone ID Related Accession (Same CDS sequence)	XM_006497009.2 , XM_006497009.3
Accession Version	XM_006497009.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	SLAM family member 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006497009.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGTCCC TCTGGAGTCT TCTTCTCTTT GAAGCTCTCC TTCCCGTTGT GGTTGTCAGT 
GTCCAAGTGC TAAGCAAGGT AGGGGACTCA GAGCTGCTGG TGGCCGAGTG TCCTCCGGGC 
TTCCAAGTGC GTGAGGCTAT CTGGCGATCT CTGTGGCCAT CGGAGGAGCT CCTGGCCACA 
TTTTTCCGAG GTTCCTTGGA GACTCTGTAC CACTCTCGTT TCCTGGGCCG AGTCCAGCTA 
TATGACAACC TCAGCCTGGA GCTTGGACCC CTGAAACCTG GAGACAGCGG CAATTTCTCT 
GTGCTGATGG TGGATACAAG GGGTCAAACC TGGACCCAGA CCCTGTATCT CAAGGTGTAC 
GCCTCCGGGA AGGCCTCCTA CAAGGACGTG CTACTGGTAG TAGTGCCAAT TACACTGTTC 
CTGATCCTGG CTGGTCTCTT TGGGGCATGG CACCATGGCC TCTGCTCAGG GAAGAAGAAG 
GATGCTTGCA CTGACGGGGT GCTTCCAGAG ACAGAGAATG CCCTCGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497072.1
CDS	760..1290
Translation	MWSLWSLLLFEALLPVVVVSVQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTRGQTWTQTLYLKVYASGKASYKDVLLVVVPITLFLILAGLFGAWHHGLCSGKKKDACTDGVLPETENALV

Target ORF information:

RefSeq Version	XM_006497009.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus SLAM family member 8 (Slamf8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497009.2

ORF Insert Sequence:

ATGTGGTCCC TCTGGAGTCT TCTTCTCTTT GAAGCTCTCC TTCCCGTTGT GGTTGTCAGT 
GTCCAAGTGC TAAGCAAGGT AGGGGACTCA GAGCTGCTGG TGGCCGAGTG TCCTCCGGGC 
TTCCAAGTGC GTGAGGCTAT CTGGCGATCT CTGTGGCCAT CGGAGGAGCT CCTGGCCACA 
TTTTTCCGAG GTTCCTTGGA GACTCTGTAC CACTCTCGTT TCCTGGGCCG AGTCCAGCTA 
TATGACAACC TCAGCCTGGA GCTTGGACCC CTGAAACCTG GAGACAGCGG CAATTTCTCT 
GTGCTGATGG TGGATACAAG GGGTCAAACC TGGACCCAGA CCCTGTATCT CAAGGTGTAC 
GCCTCCGGGA AGGCCTCCTA CAAGGACGTG CTACTGGTAG TAGTGCCAAT TACACTGTTC 
CTGATCCTGG CTGGTCTCTT TGGGGCATGG CACCATGGCC TCTGCTCAGG GAAGAAGAAG 
GATGCTTGCA CTGACGGGGT GCTTCCAGAG ACAGAGAATG CCCTCGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slamf8 ( XM_006497009.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006497072.1 Mus musculus SLAM family member 8 (Slamf8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu28855
Clone ID Related Accession (Same CDS sequence)	XM_006497009.2 , XM_006497009.3
Accession Version	XM_006497009.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	SLAM family member 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497009.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGTCCC TCTGGAGTCT TCTTCTCTTT GAAGCTCTCC TTCCCGTTGT GGTTGTCAGT 
GTCCAAGTGC TAAGCAAGGT AGGGGACTCA GAGCTGCTGG TGGCCGAGTG TCCTCCGGGC 
TTCCAAGTGC GTGAGGCTAT CTGGCGATCT CTGTGGCCAT CGGAGGAGCT CCTGGCCACA 
TTTTTCCGAG GTTCCTTGGA GACTCTGTAC CACTCTCGTT TCCTGGGCCG AGTCCAGCTA 
TATGACAACC TCAGCCTGGA GCTTGGACCC CTGAAACCTG GAGACAGCGG CAATTTCTCT 
GTGCTGATGG TGGATACAAG GGGTCAAACC TGGACCCAGA CCCTGTATCT CAAGGTGTAC 
GCCTCCGGGA AGGCCTCCTA CAAGGACGTG CTACTGGTAG TAGTGCCAAT TACACTGTTC 
CTGATCCTGG CTGGTCTCTT TGGGGCATGG CACCATGGCC TCTGCTCAGG GAAGAAGAAG 
GATGCTTGCA CTGACGGGGT GCTTCCAGAG ACAGAGAATG CCCTCGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006497072.1
CDS	442..972
Translation	MWSLWSLLLFEALLPVVVVSVQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTRGQTWTQTLYLKVYASGKASYKDVLLVVVPITLFLILAGLFGAWHHGLCSGKKKDACTDGVLPETENALV

Target ORF information:

RefSeq Version	XM_006497009.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus SLAM family member 8 (Slamf8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006497009.3

ORF Insert Sequence:

ATGTGGTCCC TCTGGAGTCT TCTTCTCTTT GAAGCTCTCC TTCCCGTTGT GGTTGTCAGT 
GTCCAAGTGC TAAGCAAGGT AGGGGACTCA GAGCTGCTGG TGGCCGAGTG TCCTCCGGGC 
TTCCAAGTGC GTGAGGCTAT CTGGCGATCT CTGTGGCCAT CGGAGGAGCT CCTGGCCACA 
TTTTTCCGAG GTTCCTTGGA GACTCTGTAC CACTCTCGTT TCCTGGGCCG AGTCCAGCTA 
TATGACAACC TCAGCCTGGA GCTTGGACCC CTGAAACCTG GAGACAGCGG CAATTTCTCT 
GTGCTGATGG TGGATACAAG GGGTCAAACC TGGACCCAGA CCCTGTATCT CAAGGTGTAC 
GCCTCCGGGA AGGCCTCCTA CAAGGACGTG CTACTGGTAG TAGTGCCAAT TACACTGTTC 
CTGATCCTGG CTGGTCTCTT TGGGGCATGG CACCATGGCC TCTGCTCAGG GAAGAAGAAG 
GATGCTTGCA CTGACGGGGT GCTTCCAGAG ACAGAGAATG CCCTCGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slamf8 ( XM_030243230.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030099090.1 Mus musculus SLAM family member 8 (Slamf8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu85275
Clone ID Related Accession (Same CDS sequence)	XM_030243230.1
Accession Version	XM_030243230.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	SLAM family member 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGATA CAAGGGGTCA AACCTGGACC CAGACCCTGT ATCTCAAGGT GTACGATGCA 
GTACCCAAGC CCGAGGTTCA AGTGTTCACT GCTGCAGCAG AGGAGACCCA ACCCCTCAAT 
ACCTGTCAGG TCTTCTTGTC CTGCTGGGCC CCCAACATCA GTGACATAAC CTACAGCTGG 
CGACGGGAGG GGACAGTGGA CTTCAATGGT GAAGTGCACA GCCATTTCTC AAATGGACAG 
GTGTTAAGTG TCTCACTGGG ACTGGGGGAC AAGGATGTGG CCTTTACCTG CATTGCCTCC 
AATCCTGTCA GCTGGGATAT GACCACAGTC ACCCCCTGGG AGAGCTGCCA TCACGAGGCA 
GCCTCCGGGA AGGCCTCCTA CAAGGACGTG CTACTGGTAG TAGTGCCAAT TACACTGTTC 
CTGATCCTGG CTGGTCTCTT TGGGGCATGG CACCATGGCC TCTGCTCAGG GAAGAAGAAG 
GATGCTTGCA CTGACGGGGT GCTTCCAGAG ACAGAGAATG CCCTCGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030099090.1
CDS	357..887
Translation	MVDTRGQTWTQTLYLKVYDAVPKPEVQVFTAAAEETQPLNTCQVFLSCWAPNISDITYSWRREGTVDFNGEVHSHFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASGKASYKDVLLVVVPITLFLILAGLFGAWHHGLCSGKKKDACTDGVLPETENALV

Target ORF information:

RefSeq Version	XM_030243230.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus SLAM family member 8 (Slamf8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030243230.1

ORF Insert Sequence:

ATGGTGGATA CAAGGGGTCA AACCTGGACC CAGACCCTGT ATCTCAAGGT GTACGATGCA 
GTACCCAAGC CCGAGGTTCA AGTGTTCACT GCTGCAGCAG AGGAGACCCA ACCCCTCAAT 
ACCTGTCAGG TCTTCTTGTC CTGCTGGGCC CCCAACATCA GTGACATAAC CTACAGCTGG 
CGACGGGAGG GGACAGTGGA CTTCAATGGT GAAGTGCACA GCCATTTCTC AAATGGACAG 
GTGTTAAGTG TCTCACTGGG ACTGGGGGAC AAGGATGTGG CCTTTACCTG CATTGCCTCC 
AATCCTGTCA GCTGGGATAT GACCACAGTC ACCCCCTGGG AGAGCTGCCA TCACGAGGCA 
GCCTCCGGGA AGGCCTCCTA CAAGGACGTG CTACTGGTAG TAGTGCCAAT TACACTGTTC 
CTGATCCTGG CTGGTCTCTT TGGGGCATGG CACCATGGCC TCTGCTCAGG GAAGAAGAAG 
GATGCTTGCA CTGACGGGGT GCTTCCAGAG ACAGAGAATG CCCTCGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8.
PloS one10(3)e0121968(2015)
Wang G,van Driel BJ,Liao G,O'Keeffe MS,Halibozek PJ,Flipse J,Yigit B,Azcutia V,Luscinskas FW,Wang N,Terhorst C

SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.
Frontiers in immunology5186(2014)
De Calisto J,Wang N,Wang G,Yigit B,Engel P,Terhorst C

Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages.
Journal of immunology (Baltimore, Md. : 1950)188(12)5829-32(2012 Jun)
Wang G,Abad?a-Molina AC,Berger SB,Romero X,O'Keeffe MS,Rojas-Barros DI,Aleman M,Liao G,Maganto-Garc?a E,Fresno M,Wang N,Detre C,Terhorst C

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

Cloning, expression, and function of BLAME, a novel member of the CD2 family.
Journal of immunology (Baltimore, Md. : 1950)166(9)5675-80(2001 May)
Kingsbury GA,Feeney LA,Nong Y,Calandra SA,Murphy CJ,Corcoran JM,Wang Y,Prabhu Das MR,Busfield SJ,Fraser CC,Villeval JL

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Slamf8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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