The following Abca12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abca12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu18323 | |
| Clone ID Related Accession (Same CDS sequence) | NM_175210.3 | |
| Accession Version | NM_175210.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 7788bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | ATP-binding cassette sub-family A member 12 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138589.16 and AC107789.7. On or before Mar 28, 2009 this sequence version replaced XM_987225.1, XM_001002308.2, NM_175210.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC158053.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCTTCCC AGTTTCATCA GCTTCGGATC CTGGTGTGGA AAAATTGGCT AGGTGTCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_780419.2 |
| CDS | 329..8116 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_175210.3 |
1 | ATGGCTTCCC AGTTTCATCA GCTTCGGATC CTGGTGTGGA AAAATTGGCT AGGTGTCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. |
Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. |
Variant mapping and mutation discovery in inbred mice using next-generation sequencing. |
Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. |
Endogenous ?-glucocerebrosidase activity in Abca12?/?epidermis elevates ceramide levels after topical lipid application but does not restore barrier function. |
