Slc7a13 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc7a13
Entrez Gene ID	74087
Full Name	solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
Synonyms	0610009O04Rik,AGT-1,AGT1,XAT2
General protein information	Preferred Names solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 Names solute carrier family 7 member 13 X-amino acid transporter 2 aspartate/glutamate transporter 1 sodium-independent aspartate/glutamate transporter 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 A3

mRNA and Protein(s)

mRNA	Protein	Name
NM_028746.3	NP_083022.1	solute carrier family 7 member 13

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC7A13	XP_001135095.1
Canis lupus familiaris (dog)	SLC7A13	XP_005638212.1
Mus musculus (house mouse)	Slc7a13	NP_083022.1
Rattus norvegicus (Norway rat)	Slc7a13	NP_001012100.1
	SLC7A13	XP_001082410.1
Homo sapiens (human)	SLC7A13	NP_620172.2

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression.
West DB, Engelhard EK, Adkisson M, Nava AJ, Kirov JV, Cipollone A, Willis B, Rapp J, de Jong PJ, Lloyd KC
PLoS genetics12(2)e1005691(2016 Feb)

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.
Nagamori S, Wiriyasermkul P, Guarch ME, Okuyama H, Nakagomi S, Tadagaki K, Nishinaka Y, Bodoy S, Takafuji K, Okuda S, Kurokawa J, Ohgaki R, Nunes V, Palac?n M, Kanai Y
Proceedings of the National Academy of Sciences of the United States of America113(3)775-80(2016 Jan)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Willnow T, Antignac C, Br?ndli A, Christensen E, Cox R, Davidson D, Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A, Meij I
Organogenesis2(2)42-7(2005 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a membrane protein AGT1/SLC7A13 is the second partner of rBAT.
Title: Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.

The following Slc7a13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc7a13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06042	NM_028746.3 Latest version!	Mus musculus solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 (Slc7a13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$279.30 $399.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc7a13 ( NM_028746.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083022.1 Mus musculus solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 (Slc7a13), mRNA.

Price & Availability↑

CloneID	OMu06042
Clone ID Related Accession (Same CDS sequence)	NM_028746.3
Accession Version	NM_028746.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	solute carrier family 7 member 13
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143768.1 and CK346971.1. On May 9, 2009 this sequence version replaced NM_028746.2. ##Evidence-Data-START## Transcript exon combination :: AK128901.1, AB072352.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385 [ECO:0000348] ##Evidence-Data-END##

ATGGCAATGG ATTCAAAGAA GGAAATCCGT CTTAAGAGAG AACTTGGATA TTTCTGGGGG 
ACAAACTTTT TAATTATTAA TATAATTGGT GCAGGAATAT TTGTGTCCCC CAAGGGAGTG 
CTCCAGCACT CTTCCATGAA TGTTGGAGTC TCCTTGTGTG TTTGGGCTGT CTGTGCAGTG 
CTGACCTTGA CCAGTGCTCT CTGCTCTGCA GAGATCGGGA TAACCTTCCC ATACAGTGGG 
GCTCACTATT ATTTTTTAAA GCGATGCTTC GGCCCTCTCG TGGCATTCCT GAGGCTTTGG 
ACTAGCTTGT TTCTCGGCCC AGGCTTAATT GCTAGCCAAG CTCTGCTACT GGCTGAGTAT 
GGCGTTCAGC CTTTTTATCC CAGCTGCTCT GCCCCGATTC TACCAAGAAA ATGTCTGGCC 
CTGGCGATGC TGTGGATTGT GGGAATTCTG AATTCTCGTG GTGTAAAAGA GCTGTCATGG 
CTTCAGACAG TGAGCTCAGT GCTGAAGGTG GGCATACTCG GTGTCATTTC CCTCAGCGGC 
CTGTTCTTGC TGGTGAGAGG GAAGAAGGAG AATGTACAAA GGCTTCAGAA TGCGTTTGAT 
GCCGAGTTCC CAGAGGTCTC TCAGTTAATA GAAGCTATTT TCCAAGGATA CTTTGCGTTT 
TCTGGCGGGG GATGCTTTAC ATGTATAGCA GGGGAGCTGA AGAAACCCAG TAAAACAATT 
CCTAGATGCA TCTTTACAGG ACTGCCTCTG GTAACTGTCG TGTACTTACT GGCTAATATT 
TCCTACCTGA CAGTTCTGAC ACCCCAGGAA ATGCTCTCTT CAGATGCTGT TGCTCTTACA 
TGGACAGACA GGGTCATTCC CCAATTCACA TGGACTGTTC CTTTTGCTAT TTCTGCTTCA 
CTGTTTATCA ACCTTGTGAT TAATGTACTT GAGACATCAA GAGTGTTATA TATTGCAAGT 
GAGAATGGCC AGCTGCCTTT GTTGTTTTGT GCCCTGAATG TCCATTCCTC TCCCTTTATA 
GCTGTGCTAC TAATTATCAG TATGGCATCC ATTTTAATTG TCTTAACAAA CCTAATTGAT 
CTGATAAACT ATCTCTATTT TGTTGTTTCC ATTTGGACTG CCTTATCAAT AATAGGAATC 
TTGAAACTGA GGTACCAAGA GCCCAATCTA CACAGACCAT ATAAGGTGTT TTTACCGTTC 
ACATTCATAG CGTTGGGCAT CACCCTGAGC TTGGTTTTGA TCCCGCTTGT CAAGTCTCCA 
AAGTTGCATT ATATCTATGT GTTCCTCTTC CTTCTCAGTG GGCTGGTGTT TTACGTGCCA 
TTGATACACT TTAAAGTGAA GTTCGTTTGG TTTCAGAAGT TGACTTGCTA TCTGCAGTTA 
CTGTTTAATA TTTGCATCCC TGATGTGTCT GATGACCACA TACATGAAGA AAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083022.1
CDS	76..1512
Translation	MAMDSKKEIRLKRELGYFWGTNFLIINIIGAGIFVSPKGVLQHSSMNVGVSLCVWAVCAVLTLTSALCSAEIGITFPYSGAHYYFLKRCFGPLVAFLRLWTSLFLGPGLIASQALLLAEYGVQPFYPSCSAPILPRKCLALAMLWIVGILNSRGVKELSWLQTVSSVLKVGILGVISLSGLFLLVRGKKENVQRLQNAFDAEFPEVSQLIEAIFQGYFAFSGGGCFTCIAGELKKPSKTIPRCIFTGLPLVTVVYLLANISYLTVLTPQEMLSSDAVALTWTDRVIPQFTWTVPFAISASLFINLVINVLETSRVLYIASENGQLPLLFCALNVHSSPFIAVLLIISMASILIVLTNLIDLINYLYFVVSIWTALSIIGILKLRYQEPNLHRPYKVFLPFTFIALGITLSLVLIPLVKSPKLHYIYVFLFLLSGLVFYVPLIHFKVKFVWFQKLTCYLQLLFNICIPDVSDDHIHEES

Target ORF information:

RefSeq Version	NM_028746.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 (Slc7a13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028746.3

ORF Insert Sequence:

ATGGCAATGG ATTCAAAGAA GGAAATCCGT CTTAAGAGAG AACTTGGATA TTTCTGGGGG 
ACAAACTTTT TAATTATTAA TATAATTGGT GCAGGAATAT TTGTGTCCCC CAAGGGAGTG 
CTCCAGCACT CTTCCATGAA TGTTGGAGTC TCCTTGTGTG TTTGGGCTGT CTGTGCAGTG 
CTGACCTTGA CCAGTGCTCT CTGCTCTGCA GAGATCGGGA TAACCTTCCC ATACAGTGGG 
GCTCACTATT ATTTTTTAAA GCGATGCTTC GGCCCTCTCG TGGCATTCCT GAGGCTTTGG 
ACTAGCTTGT TTCTCGGCCC AGGCTTAATT GCTAGCCAAG CTCTGCTACT GGCTGAGTAT 
GGCGTTCAGC CTTTTTATCC CAGCTGCTCT GCCCCGATTC TACCAAGAAA ATGTCTGGCC 
CTGGCGATGC TGTGGATTGT GGGAATTCTG AATTCTCGTG GTGTAAAAGA GCTGTCATGG 
CTTCAGACAG TGAGCTCAGT GCTGAAGGTG GGCATACTCG GTGTCATTTC CCTCAGCGGC 
CTGTTCTTGC TGGTGAGAGG GAAGAAGGAG AATGTACAAA GGCTTCAGAA TGCGTTTGAT 
GCCGAGTTCC CAGAGGTCTC TCAGTTAATA GAAGCTATTT TCCAAGGATA CTTTGCGTTT 
TCTGGCGGGG GATGCTTTAC ATGTATAGCA GGGGAGCTGA AGAAACCCAG TAAAACAATT 
CCTAGATGCA TCTTTACAGG ACTGCCTCTG GTAACTGTCG TGTACTTACT GGCTAATATT 
TCCTACCTGA CAGTTCTGAC ACCCCAGGAA ATGCTCTCTT CAGATGCTGT TGCTCTTACA 
TGGACAGACA GGGTCATTCC CCAATTCACA TGGACTGTTC CTTTTGCTAT TTCTGCTTCA 
CTGTTTATCA ACCTTGTGAT TAATGTACTT GAGACATCAA GAGTGTTATA TATTGCAAGT 
GAGAATGGCC AGCTGCCTTT GTTGTTTTGT GCCCTGAATG TCCATTCCTC TCCCTTTATA 
GCTGTGCTAC TAATTATCAG TATGGCATCC ATTTTAATTG TCTTAACAAA CCTAATTGAT 
CTGATAAACT ATCTCTATTT TGTTGTTTCC ATTTGGACTG CCTTATCAAT AATAGGAATC 
TTGAAACTGA GGTACCAAGA GCCCAATCTA CACAGACCAT ATAAGGTGTT TTTACCGTTC 
ACATTCATAG CGTTGGGCAT CACCCTGAGC TTGGTTTTGA TCCCGCTTGT CAAGTCTCCA 
AAGTTGCATT ATATCTATGT GTTCCTCTTC CTTCTCAGTG GGCTGGTGTT TTACGTGCCA 
TTGATACACT TTAAAGTGAA GTTCGTTTGG TTTCAGAAGT TGACTTGCTA TCTGCAGTTA 
CTGTTTAATA TTTGCATCCC TGATGTGTCT GATGACCACA TACATGAAGA AAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression.
PLoS genetics12(2)e1005691(2016 Feb)
West DB,Engelhard EK,Adkisson M,Nava AJ,Kirov JV,Cipollone A,Willis B,Rapp J,de Jong PJ,Lloyd KC

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.
Proceedings of the National Academy of Sciences of the United States of America113(3)775-80(2016 Jan)
Nagamori S,Wiriyasermkul P,Guarch ME,Okuyama H,Nakagomi S,Tadagaki K,Nishinaka Y,Bodoy S,Takafuji K,Okuda S,Kurokawa J,Ohgaki R,Nunes V,Palac?n M,Kanai Y

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Organogenesis2(2)42-7(2005 Apr)
Willnow T,Antignac C,Br?ndli A,Christensen E,Cox R,Davidson D,Davies J,Devuyst O,Eichele G,Hastie N,Verroust P,Schedl A,Meij I

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Slc7a13 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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