Cmtm2a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cmtm2a
Entrez Gene ID	73381
Full Name	CKLF-like MARVEL transmembrane domain containing 2A
Synonyms	1700001K04Rik,1700041N15Rik,1700063K20Rik,AI449770,ARR19,C32,CKLF3,CKLF4,CKLF5,Cklf,Cklf1,Cklfsf2-1b,Cklfsf2a,UCK-1
General protein information	Preferred Names CKLF-like MARVEL transmembrane domain containing 2A Names CKLF-like MARVEL transmembrane domain-containing protein 2A chemokine-like factor super family 2A chemokine-like factor superfamily 2-1b chemokine-like factor superfamily member 2A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_027022.4	NP_081298.1	CKLF-like MARVEL transmembrane domain-containing protein 2A

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cmtm2a	NP_081298.1
Rattus norvegicus (Norway rat)	Cmtm2a	NP_001013160.1

Gene Ontology
Bibliography

Related articles in PubMed

A time-course study of long term over-expression of ARR19 in mice.
Qamar I, Ahmad MF, Narayanasamy A
Scientific reports513014(2015 Aug)

Developmental expression of chemokine-like factor 1, a novel member of chemokines family, in postnatal rat cerebral cortex.
Wang ZZ, Zhang Y, Yuan YH, Chen NH
Neuroscience letters519(1)51-5(2012 Jun)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, these results suggest that ARR19 may play an important role in the differentiation of male reproductive organs such as testis and prostate
Title: A time-course study of long term over-expression of ARR19 in mice.

Concluding, the temporal expression pattern of CKLF1 was coincident with the postnatal developmental stages and the spatial locations of CKLF1 were some destinations of neural cell migration or regions where myelination normally occurs.
Title: Developmental expression of chemokine-like factor 1, a novel member of chemokines family, in postnatal rat cerebral cortex.

ARR19 acts as a novel coregulator of Nur77, in turn regulating Nur77-induced testicular steroidogenesis.
Title: Anti-steroidogenic factor ARR19 inhibits testicular steroidogenesis through the suppression of Nur77 transactivation.

ARR19 gene expression in testicular Leydig cells is regulated by luteinizing hormone/cAMP signaling via the control of GATA-1 expression, resulting in the control of testicular steroidogenesis
Title: ARR19 (androgen receptor corepressor of 19 kDa), an antisteroidogenic factor, is regulated by GATA-1 in testicular Leydig cells.

Data show that mouse Cklfsf2a and Cklfsf2b are two homologues of human CKLFSF2.
Title: Molecular cloning and identification of mouse Cklfsf2a and Cklfsf2b, two homologues of human CKLFSF2.

The following Cmtm2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cmtm2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03440	NM_027022.4 Latest version!	Mus musculus CKLF-like MARVEL transmembrane domain containing 2A (Cmtm2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cmtm2a ( NM_027022.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081298.1 Mus musculus CKLF-like MARVEL transmembrane domain containing 2A (Cmtm2a), mRNA.

Price & Availability↑

CloneID	OMu03440
Clone ID Related Accession (Same CDS sequence)	NM_027022.4
Accession Version	NM_027022.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 510bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Mus musculus(house mouse)
Product	CKLF-like MARVEL transmembrane domain-containing protein 2A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK006874.1 and AY241871.1. On Feb 24, 2007 this sequence version replaced NM_027022.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY241871.1, AK161303.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCAC CGATAAAGTT TCCATTTCGG CCCAGAGGAG GTCAGCCCAG AGAGGACACG 
ACCCCAAAAA GGGGGCTTCG ACGCTATCTA TTGGAATTGA AAGAGAGCAA TAAAGAGTTC 
TGGCTGTCAG GACACGCCGT GTTCAAGCTT CTGTCTTTGG GCTGCATGAT CTCTGCACTA 
GACTACTTTG AAACAATGCT CCCACATCCG GTCCTGATCC TGCTCATCTG TATGGAAGCG 
GCAATCTGCA TATTCTTCAT CTTCCTTAAC ACCTTAGCCA TCAACAGATA CATTCCCTTC 
GTCTTCTGGC CTATGGCGGA TATCTTCAAC AGCCTGTTCT CCTGTGTGTT CCTTGGAGGT 
GGCATATACT TTGCTTTCAA GGCTAGAAGA TTATTGCCAA AGCCCTACTT AACTGCTATG 
ATCCTCATGG GCGCTGCTGC GATCTGTTCT TTCATCGACA TGTTACTTCA ATTCCAACAC 
TTCAGAGGCC TTAGGTTAAG GAAGTGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081298.1
CDS	126..635
Translation	MAAPIKFPFRPRGGQPREDTTPKRGLRRYLLELKESNKEFWLSGHAVFKLLSLGCMISALDYFETMLPHPVLILLICMEAAICIFFIFLNTLAINRYIPFVFWPMADIFNSLFSCVFLGGGIYFAFKARRLLPKPYLTAMILMGAAAICSFIDMLLQFQHFRGLRLRKW

Target ORF information:

RefSeq Version	NM_027022.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus CKLF-like MARVEL transmembrane domain containing 2A (Cmtm2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027022.4

ORF Insert Sequence:

ATGGCAGCAC CGATAAAGTT TCCATTTCGG CCCAGAGGAG GTCAGCCCAG AGAGGACACG 
ACCCCAAAAA GGGGGCTTCG ACGCTATCTA TTGGAATTGA AAGAGAGCAA TAAAGAGTTC 
TGGCTGTCAG GACACGCCGT GTTCAAGCTT CTGTCTTTGG GCTGCATGAT CTCTGCACTA 
GACTACTTTG AAACAATGCT CCCACATCCG GTCCTGATCC TGCTCATCTG TATGGAAGCG 
GCAATCTGCA TATTCTTCAT CTTCCTTAAC ACCTTAGCCA TCAACAGATA CATTCCCTTC 
GTCTTCTGGC CTATGGCGGA TATCTTCAAC AGCCTGTTCT CCTGTGTGTT CCTTGGAGGT 
GGCATATACT TTGCTTTCAA GGCTAGAAGA TTATTGCCAA AGCCCTACTT AACTGCTATG 
ATCCTCATGG GCGCTGCTGC GATCTGTTCT TTCATCGACA TGTTACTTCA ATTCCAACAC 
TTCAGAGGCC TTAGGTTAAG GAAGTGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A time-course study of long term over-expression of ARR19 in mice.
Scientific reports513014(2015 Aug)
Qamar I,Ahmad MF,Narayanasamy A

Developmental expression of chemokine-like factor 1, a novel member of chemokines family, in postnatal rat cerebral cortex.
Neuroscience letters519(1)51-5(2012 Jun)
Wang ZZ,Zhang Y,Yuan YH,Chen NH

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

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Cmtm2a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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