Tppp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tppp
Entrez Gene ID	72948
Full Name	tubulin polymerization promoting protein
Synonyms	2900041A09Rik,AI849835
General protein information	Preferred Names tubulin polymerization promoting protein Names tubulin polymerization-promoting protein brain-specific protein p25 alpha
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 C1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006517409.3	XP_006517472.1	tubulin polymerization-promoting protein isoform X1
NM_182839.2	NP_878259.1	tubulin polymerization-promoting protein
XM_006517409.2	XP_006517472.1	tubulin polymerization-promoting protein isoform X1
XM_006517409.4	XP_006517472.1	tubulin polymerization-promoting protein isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Tppp	NP_001101931.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006948	XP_308808.4
	TPPP	XP_001095130.1
Bos taurus (cattle)	TPPP	NP_776401.1
Mus musculus (house mouse)	Tppp	NP_878259.1
Gallus gallus (chicken)	TPPP	XP_418894.1
Drosophila melanogaster (fruit fly)	CG4893	NP_001261939.1
Pan troglodytes (chimpanzee)	TPPP	XP_003310658.1
Canis lupus familiaris (dog)	TPPP	XP_545196.3
Homo sapiens (human)	TPPP	NP_008961.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of genes involved in stress, neural plasticity, and brain circuitry in depressive phenotypes: Convergent findings in a mouse model of neglect.
Montalvo-Ortiz JL, Bordner KA, Carlyle BC, Gelernter J, Simen AA, Kaufman J
Behavioural brain research31571-4(2016 12)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.
He D, Marie C, Zhao C, Kim B, Wang J, Deng Y, Clavairoly A, Frah M, Wang H, He X, Hmidan H, Jones BV, Witte D, Zalc B, Zhou X, Choo DI, Martin DM, Parras C, Lu QR
Nature neuroscience19(5)678-689(2016 05)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The present study provides additional support for roles for TPPP in the etiology of depression following early adversity.
Title: The role of genes involved in stress, neural plasticity, and brain circuitry in depressive phenotypes: Convergent findings in a mouse model of neglect.

These results support an essential role for TPPP/p25 in oligodendrocyte differentiation likely via rearrangement of the microtubule system during the process elongation prior to the onset of myelination.
Title: Tubulin polymerization-promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation.

A pathway was discovered by which p25 and cdk5 increases the amyloidogenic processing of amyloid precursor protein.
Title: Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing.

LIMK1 phosphorylation of p25 blocks p25 activity, thus promoting microtubule disassembly.
Title: The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules.

The following Tppp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tppp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu08245	NM_182839.2 Latest version!	Mus musculus tubulin polymerization promoting protein (Tppp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu08245	XM_006517409.4 Latest version!	Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu08245	XM_006517409.2	Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu08245	XM_006517409.3	Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tppp ( NM_182839.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_878259.1 Mus musculus tubulin polymerization promoting protein (Tppp), mRNA.

Price & Availability↑

CloneID	OMu08245
Clone ID Related Accession (Same CDS sequence)	XM_006517409.3 , NM_182839.2 , XM_006517409.2 , XM_006517409.4
Accession Version	NM_182839.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	tubulin polymerization-promoting protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY124320.1, BC054803.1 and BM898784.1. On Oct 27, 2009 this sequence version replaced NM_182839.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC054803.1, SRR1660819.184066.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_878259.1
CDS	96..752
Translation	MADSKAKPAKAANKTPPKSPGDPARAAKRLSLESEGANEGATAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQKVQGGK

Target ORF information:

RefSeq Version	NM_182839.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polymerization promoting protein (Tppp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182839.2

ORF Insert Sequence:

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tppp ( XM_006517409.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517472.1 Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08245
Clone ID Related Accession (Same CDS sequence)	XM_006517409.3 , NM_182839.2 , XM_006517409.2 , XM_006517409.4
Accession Version	XM_006517409.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	tubulin polymerization-promoting protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517409.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517472.1
CDS	69..725
Translation	MADSKAKPAKAANKTPPKSPGDPARAAKRLSLESEGANEGATAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQKVQGGK

Target ORF information:

RefSeq Version	XM_006517409.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517409.3

ORF Insert Sequence:

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tppp ( XM_006517409.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517472.1 Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08245
Clone ID Related Accession (Same CDS sequence)	XM_006517409.3 , NM_182839.2 , XM_006517409.2 , XM_006517409.4
Accession Version	XM_006517409.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	tubulin polymerization-promoting protein isoform X1
Comment

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517472.1
Translation	MADSKAKPAKAANKTPPKSPGDPARAAKRLSLESEGANEGATAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQKVQGGK

Target ORF information:

RefSeq Version	XM_006517409.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517409.2

ORF Insert Sequence:

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tppp ( XM_006517409.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517472.1 Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08245
Clone ID Related Accession (Same CDS sequence)	XM_006517409.3 , NM_182839.2 , XM_006517409.2 , XM_006517409.4
Accession Version	XM_006517409.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	tubulin polymerization-promoting protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006517409.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517472.1
CDS	94..750
Translation	MADSKAKPAKAANKTPPKSPGDPARAAKRLSLESEGANEGATAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQKVQGGK

Target ORF information:

RefSeq Version	XM_006517409.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polymerization promoting protein (Tppp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517409.4

ORF Insert Sequence:

ATGGCTGACA GCAAGGCCAA GCCTGCCAAA GCTGCCAACA AGACACCACC CAAGTCCCCA 
GGAGACCCAG CCAGGGCTGC TAAGAGGTTG TCACTGGAGT CAGAGGGTGC CAATGAGGGT 
GCAACTGCAG CTCCTGAGCT CAGTGCCCTG GAGGAGGCCT TCCGGCGGTT TGCAGTACAT 
GGGGACACCA GGGCAACAGG AAAGGAGATG CATGGCAAGA ACTGGTCAAA ACTGTGCAAG 
GACTGCCACG TGATCGATGG GAAGAATGTG ACCGTCACTG ACGTGGACAT TGTCTTCAGC 
AAGATCAAAG GAAAGTCCTG CAGGACCATC ACCTTTGAGC AGTTCCAGGA GGCACTGGAG 
GAGCTGGCCA AGAAGCGGTT CAAGGATAAG AGCAGCGAGG AGGCTGTACG TGAGGTGCAC 
AGGCTCATTG AGGGACGAGC ACCAGTCATC TCTGGCGTCA CGAAAGCTGT GTCCTCACCC 
ACGGTGTCAC GGCTCACAGA CACAAGCAAG TTCACAGGTT CCCACAAGGA GCGTTTCGAC 
CAATCAGGAA AGGGCAAGGG CAAAGCTGGC CGTGTGGACC TGGTGGATGA GTCAGGCTAT 
GTGCCTGGTT ACAAGCATGC AGGCACCTAT GACCAGAAGG TGCAGGGGGG CAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of genes involved in stress, neural plasticity, and brain circuitry in depressive phenotypes: Convergent findings in a mouse model of neglect.
Behavioural brain research31571-4(2016 12)
Montalvo-Ortiz JL,Bordner KA,Carlyle BC,Gelernter J,Simen AA,Kaufman J

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
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Tppp cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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