Lrpprc cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrpprc
Entrez Gene ID	72416
Full Name	leucine-rich PPR-motif containing
Synonyms	3110001K13Rik,C76645,Gp130,Lrp130,Lsfc
General protein information	Preferred Names leucine-rich PPR-motif containing Names leucine-rich PPR motif-containing protein, mitochondrial 130 kDa leucine-rich protein leucine rich protein LRP130
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 E4

mRNA and Protein(s)

mRNA	Protein	Name
XM_011246643.2	XP_011244945.1	leucine-rich PPR motif-containing protein, mitochondrial isoform X1
XM_011246643.3	XP_011244945.1	leucine-rich PPR motif-containing protein, mitochondrial isoform X1
NM_028233.2	NP_082509.2	leucine-rich PPR motif-containing protein, mitochondrial precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRPPRC	NP_573566.2
Mus musculus (house mouse)	Lrpprc	NP_082509.2
Rattus norvegicus (Norway rat)	Lrpprc	NP_001008519.1
Danio rerio (zebrafish)	lrpprc	NP_001136064.1
Xenopus tropicalis (tropical clawed frog)	lrpprc	NP_001039203.1
Pan troglodytes (chimpanzee)	LRPPRC	XP_001143797.1
	LRPPRC	XP_001107298.2
Canis lupus familiaris (dog)	LRPPRC	XP_531800.2
Gallus gallus (chicken)	LRPPRC	XP_001234903.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008770	XP_557938.3
Bos taurus (cattle)	LRPPRC	XP_002691297.2
Drosophila melanogaster (fruit fly)	bsf	NP_523596.2

Gene Ontology
Bibliography

Related articles in PubMed

LRPPRC-mediated folding of the mitochondrial transcriptome.
Siira SJ, Sp?hr H, Shearwood AJ, Ruzzenente B, Larsson NG, Rackham O, Filipovska A
Nature communications8(1)1532(2017 Nov)

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals.
K?hl I, Miranda M, Atanassov I, Kuznetsova I, Hinze Y, Mourier A, Filipovska A, Larsson NG
eLife6(2017 Nov)

Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion.
Cuillerier A, Honarmand S, Cadete VJJ, Ruiz M, Forest A, Desch?nes S, Beauchamp C, , Charron G, Rioux JD, Des Rosiers C, Shoubridge EA, Burelle Y
Human molecular genetics26(16)3186-3201(2017 Aug)

An unexpected role for the transcriptional coactivator isoform NT-PGC-1? in the regulation of mitochondrial respiration in brown adipocytes.
Chang JS, Ha K
The Journal of biological chemistry292(24)9958-9966(2017 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest NT-Pgc-1alpha (alternative splicing isoform of nuclear protein Pgc-1alpha) is located in mitochondrial matrix in brown adipocytes, specifically enriched at D-loop region of mitochondrial DNA at promoter region of Lrpprc (leucine-rich PPR-motif containing protein); expression of NT-Pgc-1alpha (rather than Pgc-1alpha) in brown adipocytes appears to induce expression of electron transport chain complex proteins.
Title: An unexpected role for the transcriptional coactivator isoform NT-PGC-1? in the regulation of mitochondrial respiration in brown adipocytes.

both LRPPRC and SLIRP are required for maintaining mt-mRNA steady-state levels independent of their roles in stabilizing the other partner of the LRPPRC-SLIRP complex.
Title: SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation.

Ectopic expression of LRPPRC in the mouse liver completely interdicted non-alcoholic fatty liver disease, including inflammation.
Title: OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease.

LRPPRC deficiency in Leigh syndrome causes an ATP synthase deficiency.
Title: Loss of LRPPRC causes ATP synthase deficiency.

LRPPRC does not directly regulate mtDNA transcription but rather acts as a post-transcriptional regulator of mammalian mtDNA expression.
Title: The leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) does not activate transcription in mammalian mitochondria.

The following Lrpprc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrpprc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu70909	XM_011246643.3 Latest version!	Mus musculus leucine-rich PPR-motif containing (Lrpprc), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu14788	NM_028233.2 Latest version!	Mus musculus leucine-rich PPR-motif containing (Lrpprc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$818.30 $1169.00
View Old Accession Versions >>
OMu70909	XM_011246643.2	Mus musculus leucine-rich PPR-motif containing (Lrpprc), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrpprc ( XM_011246643.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244945.1 Mus musculus leucine-rich PPR-motif containing (Lrpprc), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70909
Clone ID Related Accession (Same CDS sequence)	XM_011246643.2 , XM_011246643.3
Accession Version	XM_011246643.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2100bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	leucine-rich PPR motif-containing protein, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246643.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAAAGG CCCTTGAGGT GAAAGCAAAA TATGAGTCAG ACATGGTTAT TGGTGGCTAT 
GCAGCATTAA TAAATTTGTG CTGTCGACAT GATAATGCAG AAGATGCGTG GAACTTGAAA 
CAAGAAGTTG ACCGCTTAGA TGCTTCGGCT ATTCTTGACA CTGCCAAGTA CGTAGCCCTT 
GTAAAAGTAC TGGGAAAGCA CAGCAGACTC CAAGATGCTA TTAACATTCT AAAGGAGATG 
AAAGAGAAGG ATGTTGTTAT CAAAGATGCA ACAGTCTTGT CCTTTTTCCA CATCCTCAAT 
GGTGCAGCTT TAAGAGGTGA AATTGAAACA GTAAAACAGC TGCATGAAGC CATCGTGACT 
CTTGGGTTGG CAAAGCCGTC CAGCAACATA AGCTTCCCGT TGGTCACTGT GCACCTGGAA 
AAGGGTGACT TACCTGCTGC TCTTGAAGCC AGCATTGCCT GCCATAAAAA ATATAAAGTG 
TTACCCAGGA TTCATGATGT CTTATGTAAG CTAGTAGAGA AAGGCGAGAC TGATTTGATC 
CAGAAAGCAA TGGACTTTGT GAGCCAAGAA CAAGGGGAGA TGACGATGCT CTACGACCTC 
TTCTTTGCTT TCCTGCAGAC GGGGAATTAC AAAGAAGCTA AGAAGATCAT TGAGACTCCA 
GGCATTAGAG CTCGGCCTAC AAGACTCCAG TGGTTTTGTG ATCGATGCAT TGCCAGTAAT 
CAGGTTGAAG CTCTTGAGAA GTTGGTAGAG CTGACTGAGA AGCTGTTTGA GTGTGACAGA 
GACCAGATGT ACTACAACTT ACTGAAGCTA TACAAAATAA GCAGTGACTG GCAAAGAGCG 
GATGCTGCGT GGACCAAAAT GCAAGAAGAG AACATTATCC CTCGAGAGCG GACACTGCGG 
CTCTTAGCCG AGATCTTGAA AACCAGCAAC CAGGAAGTTC CTTTCGACGT TCCGGAGTTG 
TGGTTTGGAG ATGACAGACC TTCCCTGAGT CCATCCTCAC GCTCAGCAGG AGAGGACGTT 
ACTGAGAAGA CGTTGTTGTC TAACTGCAAA CTAAAGAAGA GTAAAGATGC ATATAATATC 
TTCCTTAAAG CCGAAAAGCA AAACGTTGTA TTTAGCAGTG AAACTTATAG CACCTTGATA 
GGCTTGCTGC TGAGTAAGGA CGACTTCACC CAAGCAATGC ACGTGAAGGA TTTCGCTGAG 
ACCCACATCA AGGGCTTCAC ACTGAACGAT GCTGCCAACA GCCTCCTCAT CATAAGGCAA 
GTTAGGCGGG ATTATTTGAA AGGGGCTCTG GCAACTCTGA GAGCAGCCTT GGATTTGAAG 
CAGGTTCCGT CCCAGATCGC CGTGACCCGC CTCATCCAGG CGTTGGCCTT GAAGGGTGAT 
GTGGAAAGCA TAGAGGCCAT TCAGAGAATG GTGGCTGGAC TTGACACGAT TGGACTCTCA 
AAAATGGTTT TTATCAATAA CATCGCTTTG GCCCAGATGA AGAATAATAA ACTTGATGCT 
GCCATAGAAA ACATTGAGCA CCTGCTTGCT TCCGAGAACC AAGCCATAGA ACCTCAGTAC 
TTTGGCTTGT CGTATCTATT CAGAAAAGTG ATCGAAGAGC AGATGGAACC AGCGCTAGAG 
AAGTTAAGCA TCATGTCTGA GAGAATGGCG AATCAGTTTG CACTTTACAA GCCCGTCACT 
GATCTATTCC TGCAGCTTGT GGATTCAGGC AAGGTGGATG AGGCCAGAGC TCTCTTAGAG 
AGATGCGGTG CCATTGCCGA GCAGAGCTCG CTTCTGTCGG TGTTCTGTCT GAGGACTTCT 
CAGAAACCGA AAAAGGCACC AGTTCTGAAG ACTTTGTTAG AACTGATTCC TGAGTTACGT 
GATAACGATA AAGTATATTC TTGCAGCATG AAAAGCTATG CCTTAGACAA AGATGTGGCC 
TCGGCTAAAG CACTGTATGA GTATTTGACA GCCAAGAACT TGAAGCTAGA TGACCTGTTT 
CTCAAGCGCT ATGCAGCTTT GCTCAAGGAT GTCGGCGAAC CAGTCCCCTT CCCCGAGCCC 
CCTGAAAGCT TTGCATTTTA TATAAAGCAA CTAAAGGAAG CAAGGGAAAG CCCTTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244945.1
CDS	688..2787
Translation	MQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDAWNLKQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKGDLPAALEASIACHKKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVELTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFDVPELWFGDDRPSLSPSSRSAGEDVTEKTLLSNCKLKKSKDAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDFTQAMHVKDFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLDTIGLSKMVFINNIALAQMKNNKLDAAIENIEHLLASENQAIEPQYFGLSYLFRKVIEEQMEPALEKLSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKAPVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS

Target ORF information:

RefSeq Version	XM_011246643.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine-rich PPR-motif containing (Lrpprc), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246643.2

ORF Insert Sequence:

ATGCAAAAGG CCCTTGAGGT GAAAGCAAAA TATGAGTCAG ACATGGTTAT TGGTGGCTAT 
GCAGCATTAA TAAATTTGTG CTGTCGACAT GATAATGCAG AAGATGCGTG GAACTTGAAA 
CAAGAAGTTG ACCGCTTAGA TGCTTCGGCT ATTCTTGACA CTGCCAAGTA CGTAGCCCTT 
GTAAAAGTAC TGGGAAAGCA CAGCAGACTC CAAGATGCTA TTAACATTCT AAAGGAGATG 
AAAGAGAAGG ATGTTGTTAT CAAAGATGCA ACAGTCTTGT CCTTTTTCCA CATCCTCAAT 
GGTGCAGCTT TAAGAGGTGA AATTGAAACA GTAAAACAGC TGCATGAAGC CATCGTGACT 
CTTGGGTTGG CAAAGCCGTC CAGCAACATA AGCTTCCCGT TGGTCACTGT GCACCTGGAA 
AAGGGTGACT TACCTGCTGC TCTTGAAGCC AGCATTGCCT GCCATAAAAA ATATAAAGTG 
TTACCCAGGA TTCATGATGT CTTATGTAAG CTAGTAGAGA AAGGCGAGAC TGATTTGATC 
CAGAAAGCAA TGGACTTTGT GAGCCAAGAA CAAGGGGAGA TGACGATGCT CTACGACCTC 
TTCTTTGCTT TCCTGCAGAC GGGGAATTAC AAAGAAGCTA AGAAGATCAT TGAGACTCCA 
GGCATTAGAG CTCGGCCTAC AAGACTCCAG TGGTTTTGTG ATCGATGCAT TGCCAGTAAT 
CAGGTTGAAG CTCTTGAGAA GTTGGTAGAG CTGACTGAGA AGCTGTTTGA GTGTGACAGA 
GACCAGATGT ACTACAACTT ACTGAAGCTA TACAAAATAA GCAGTGACTG GCAAAGAGCG 
GATGCTGCGT GGACCAAAAT GCAAGAAGAG AACATTATCC CTCGAGAGCG GACACTGCGG 
CTCTTAGCCG AGATCTTGAA AACCAGCAAC CAGGAAGTTC CTTTCGACGT TCCGGAGTTG 
TGGTTTGGAG ATGACAGACC TTCCCTGAGT CCATCCTCAC GCTCAGCAGG AGAGGACGTT 
ACTGAGAAGA CGTTGTTGTC TAACTGCAAA CTAAAGAAGA GTAAAGATGC ATATAATATC 
TTCCTTAAAG CCGAAAAGCA AAACGTTGTA TTTAGCAGTG AAACTTATAG CACCTTGATA 
GGCTTGCTGC TGAGTAAGGA CGACTTCACC CAAGCAATGC ACGTGAAGGA TTTCGCTGAG 
ACCCACATCA AGGGCTTCAC ACTGAACGAT GCTGCCAACA GCCTCCTCAT CATAAGGCAA 
GTTAGGCGGG ATTATTTGAA AGGGGCTCTG GCAACTCTGA GAGCAGCCTT GGATTTGAAG 
CAGGTTCCGT CCCAGATCGC CGTGACCCGC CTCATCCAGG CGTTGGCCTT GAAGGGTGAT 
GTGGAAAGCA TAGAGGCCAT TCAGAGAATG GTGGCTGGAC TTGACACGAT TGGACTCTCA 
AAAATGGTTT TTATCAATAA CATCGCTTTG GCCCAGATGA AGAATAATAA ACTTGATGCT 
GCCATAGAAA ACATTGAGCA CCTGCTTGCT TCCGAGAACC AAGCCATAGA ACCTCAGTAC 
TTTGGCTTGT CGTATCTATT CAGAAAAGTG ATCGAAGAGC AGATGGAACC AGCGCTAGAG 
AAGTTAAGCA TCATGTCTGA GAGAATGGCG AATCAGTTTG CACTTTACAA GCCCGTCACT 
GATCTATTCC TGCAGCTTGT GGATTCAGGC AAGGTGGATG AGGCCAGAGC TCTCTTAGAG 
AGATGCGGTG CCATTGCCGA GCAGAGCTCG CTTCTGTCGG TGTTCTGTCT GAGGACTTCT 
CAGAAACCGA AAAAGGCACC AGTTCTGAAG ACTTTGTTAG AACTGATTCC TGAGTTACGT 
GATAACGATA AAGTATATTC TTGCAGCATG AAAAGCTATG CCTTAGACAA AGATGTGGCC 
TCGGCTAAAG CACTGTATGA GTATTTGACA GCCAAGAACT TGAAGCTAGA TGACCTGTTT 
CTCAAGCGCT ATGCAGCTTT GCTCAAGGAT GTCGGCGAAC CAGTCCCCTT CCCCGAGCCC 
CCTGAAAGCT TTGCATTTTA TATAAAGCAA CTAAAGGAAG CAAGGGAAAG CCCTTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrpprc ( XM_011246643.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244945.1 Mus musculus leucine-rich PPR-motif containing (Lrpprc), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70909
Clone ID Related Accession (Same CDS sequence)	XM_011246643.2 , XM_011246643.3
Accession Version	XM_011246643.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2100bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	leucine-rich PPR motif-containing protein, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011246643.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAAAGG CCCTTGAGGT GAAAGCAAAA TATGAGTCAG ACATGGTTAT TGGTGGCTAT 
GCAGCATTAA TAAATTTGTG CTGTCGACAT GATAATGCAG AAGATGCGTG GAACTTGAAA 
CAAGAAGTTG ACCGCTTAGA TGCTTCGGCT ATTCTTGACA CTGCCAAGTA CGTAGCCCTT 
GTAAAAGTAC TGGGAAAGCA CAGCAGACTC CAAGATGCTA TTAACATTCT AAAGGAGATG 
AAAGAGAAGG ATGTTGTTAT CAAAGATGCA ACAGTCTTGT CCTTTTTCCA CATCCTCAAT 
GGTGCAGCTT TAAGAGGTGA AATTGAAACA GTAAAACAGC TGCATGAAGC CATCGTGACT 
CTTGGGTTGG CAAAGCCGTC CAGCAACATA AGCTTCCCGT TGGTCACTGT GCACCTGGAA 
AAGGGTGACT TACCTGCTGC TCTTGAAGCC AGCATTGCCT GCCATAAAAA ATATAAAGTG 
TTACCCAGGA TTCATGATGT CTTATGTAAG CTAGTAGAGA AAGGCGAGAC TGATTTGATC 
CAGAAAGCAA TGGACTTTGT GAGCCAAGAA CAAGGGGAGA TGACGATGCT CTACGACCTC 
TTCTTTGCTT TCCTGCAGAC GGGGAATTAC AAAGAAGCTA AGAAGATCAT TGAGACTCCA 
GGCATTAGAG CTCGGCCTAC AAGACTCCAG TGGTTTTGTG ATCGATGCAT TGCCAGTAAT 
CAGGTTGAAG CTCTTGAGAA GTTGGTAGAG CTGACTGAGA AGCTGTTTGA GTGTGACAGA 
GACCAGATGT ACTACAACTT ACTGAAGCTA TACAAAATAA GCAGTGACTG GCAAAGAGCG 
GATGCTGCGT GGACCAAAAT GCAAGAAGAG AACATTATCC CTCGAGAGCG GACACTGCGG 
CTCTTAGCCG AGATCTTGAA AACCAGCAAC CAGGAAGTTC CTTTCGACGT TCCGGAGTTG 
TGGTTTGGAG ATGACAGACC TTCCCTGAGT CCATCCTCAC GCTCAGCAGG AGAGGACGTT 
ACTGAGAAGA CGTTGTTGTC TAACTGCAAA CTAAAGAAGA GTAAAGATGC ATATAATATC 
TTCCTTAAAG CCGAAAAGCA AAACGTTGTA TTTAGCAGTG AAACTTATAG CACCTTGATA 
GGCTTGCTGC TGAGTAAGGA CGACTTCACC CAAGCAATGC ACGTGAAGGA TTTCGCTGAG 
ACCCACATCA AGGGCTTCAC ACTGAACGAT GCTGCCAACA GCCTCCTCAT CATAAGGCAA 
GTTAGGCGGG ATTATTTGAA AGGGGCTCTG GCAACTCTGA GAGCAGCCTT GGATTTGAAG 
CAGGTTCCGT CCCAGATCGC CGTGACCCGC CTCATCCAGG CGTTGGCCTT GAAGGGTGAT 
GTGGAAAGCA TAGAGGCCAT TCAGAGAATG GTGGCTGGAC TTGACACGAT TGGACTCTCA 
AAAATGGTTT TTATCAATAA CATCGCTTTG GCCCAGATGA AGAATAATAA ACTTGATGCT 
GCCATAGAAA ACATTGAGCA CCTGCTTGCT TCCGAGAACC AAGCCATAGA ACCTCAGTAC 
TTTGGCTTGT CGTATCTATT CAGAAAAGTG ATCGAAGAGC AGATGGAACC AGCGCTAGAG 
AAGTTAAGCA TCATGTCTGA GAGAATGGCG AATCAGTTTG CACTTTACAA GCCCGTCACT 
GATCTATTCC TGCAGCTTGT GGATTCAGGC AAGGTGGATG AGGCCAGAGC TCTCTTAGAG 
AGATGCGGTG CCATTGCCGA GCAGAGCTCG CTTCTGTCGG TGTTCTGTCT GAGGACTTCT 
CAGAAACCGA AAAAGGCACC AGTTCTGAAG ACTTTGTTAG AACTGATTCC TGAGTTACGT 
GATAACGATA AAGTATATTC TTGCAGCATG AAAAGCTATG CCTTAGACAA AGATGTGGCC 
TCGGCTAAAG CACTGTATGA GTATTTGACA GCCAAGAACT TGAAGCTAGA TGACCTGTTT 
CTCAAGCGCT ATGCAGCTTT GCTCAAGGAT GTCGGCGAAC CAGTCCCCTT CCCCGAGCCC 
CCTGAAAGCT TTGCATTTTA TATAAAGCAA CTAAAGGAAG CAAGGGAAAG CCCTTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244945.1
CDS	688..2787
Translation	MQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDAWNLKQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKGDLPAALEASIACHKKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVELTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFDVPELWFGDDRPSLSPSSRSAGEDVTEKTLLSNCKLKKSKDAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDFTQAMHVKDFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLDTIGLSKMVFINNIALAQMKNNKLDAAIENIEHLLASENQAIEPQYFGLSYLFRKVIEEQMEPALEKLSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKAPVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS

Target ORF information:

RefSeq Version	XM_011246643.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine-rich PPR-motif containing (Lrpprc), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246643.3

ORF Insert Sequence:

ATGCAAAAGG CCCTTGAGGT GAAAGCAAAA TATGAGTCAG ACATGGTTAT TGGTGGCTAT 
GCAGCATTAA TAAATTTGTG CTGTCGACAT GATAATGCAG AAGATGCGTG GAACTTGAAA 
CAAGAAGTTG ACCGCTTAGA TGCTTCGGCT ATTCTTGACA CTGCCAAGTA CGTAGCCCTT 
GTAAAAGTAC TGGGAAAGCA CAGCAGACTC CAAGATGCTA TTAACATTCT AAAGGAGATG 
AAAGAGAAGG ATGTTGTTAT CAAAGATGCA ACAGTCTTGT CCTTTTTCCA CATCCTCAAT 
GGTGCAGCTT TAAGAGGTGA AATTGAAACA GTAAAACAGC TGCATGAAGC CATCGTGACT 
CTTGGGTTGG CAAAGCCGTC CAGCAACATA AGCTTCCCGT TGGTCACTGT GCACCTGGAA 
AAGGGTGACT TACCTGCTGC TCTTGAAGCC AGCATTGCCT GCCATAAAAA ATATAAAGTG 
TTACCCAGGA TTCATGATGT CTTATGTAAG CTAGTAGAGA AAGGCGAGAC TGATTTGATC 
CAGAAAGCAA TGGACTTTGT GAGCCAAGAA CAAGGGGAGA TGACGATGCT CTACGACCTC 
TTCTTTGCTT TCCTGCAGAC GGGGAATTAC AAAGAAGCTA AGAAGATCAT TGAGACTCCA 
GGCATTAGAG CTCGGCCTAC AAGACTCCAG TGGTTTTGTG ATCGATGCAT TGCCAGTAAT 
CAGGTTGAAG CTCTTGAGAA GTTGGTAGAG CTGACTGAGA AGCTGTTTGA GTGTGACAGA 
GACCAGATGT ACTACAACTT ACTGAAGCTA TACAAAATAA GCAGTGACTG GCAAAGAGCG 
GATGCTGCGT GGACCAAAAT GCAAGAAGAG AACATTATCC CTCGAGAGCG GACACTGCGG 
CTCTTAGCCG AGATCTTGAA AACCAGCAAC CAGGAAGTTC CTTTCGACGT TCCGGAGTTG 
TGGTTTGGAG ATGACAGACC TTCCCTGAGT CCATCCTCAC GCTCAGCAGG AGAGGACGTT 
ACTGAGAAGA CGTTGTTGTC TAACTGCAAA CTAAAGAAGA GTAAAGATGC ATATAATATC 
TTCCTTAAAG CCGAAAAGCA AAACGTTGTA TTTAGCAGTG AAACTTATAG CACCTTGATA 
GGCTTGCTGC TGAGTAAGGA CGACTTCACC CAAGCAATGC ACGTGAAGGA TTTCGCTGAG 
ACCCACATCA AGGGCTTCAC ACTGAACGAT GCTGCCAACA GCCTCCTCAT CATAAGGCAA 
GTTAGGCGGG ATTATTTGAA AGGGGCTCTG GCAACTCTGA GAGCAGCCTT GGATTTGAAG 
CAGGTTCCGT CCCAGATCGC CGTGACCCGC CTCATCCAGG CGTTGGCCTT GAAGGGTGAT 
GTGGAAAGCA TAGAGGCCAT TCAGAGAATG GTGGCTGGAC TTGACACGAT TGGACTCTCA 
AAAATGGTTT TTATCAATAA CATCGCTTTG GCCCAGATGA AGAATAATAA ACTTGATGCT 
GCCATAGAAA ACATTGAGCA CCTGCTTGCT TCCGAGAACC AAGCCATAGA ACCTCAGTAC 
TTTGGCTTGT CGTATCTATT CAGAAAAGTG ATCGAAGAGC AGATGGAACC AGCGCTAGAG 
AAGTTAAGCA TCATGTCTGA GAGAATGGCG AATCAGTTTG CACTTTACAA GCCCGTCACT 
GATCTATTCC TGCAGCTTGT GGATTCAGGC AAGGTGGATG AGGCCAGAGC TCTCTTAGAG 
AGATGCGGTG CCATTGCCGA GCAGAGCTCG CTTCTGTCGG TGTTCTGTCT GAGGACTTCT 
CAGAAACCGA AAAAGGCACC AGTTCTGAAG ACTTTGTTAG AACTGATTCC TGAGTTACGT 
GATAACGATA AAGTATATTC TTGCAGCATG AAAAGCTATG CCTTAGACAA AGATGTGGCC 
TCGGCTAAAG CACTGTATGA GTATTTGACA GCCAAGAACT TGAAGCTAGA TGACCTGTTT 
CTCAAGCGCT ATGCAGCTTT GCTCAAGGAT GTCGGCGAAC CAGTCCCCTT CCCCGAGCCC 
CCTGAAAGCT TTGCATTTTA TATAAAGCAA CTAAAGGAAG CAAGGGAAAG CCCTTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrpprc ( NM_028233.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082509.2 Mus musculus leucine-rich PPR-motif containing (Lrpprc), mRNA.

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CloneID	OMu14788
Clone ID Related Accession (Same CDS sequence)	NM_028233.2
Accession Version	NM_028233.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Mus musculus(house mouse)
Product	leucine-rich PPR motif-containing protein, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC165360.3 and BC059862.1. On Mar 23, 2007 this sequence version replaced NM_028233.1. CCDS Note: The coding region has been updated to extend the N-terminus to one that is more supported by available transcript and homology data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060199.1, SRR1660813.175779.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta regulatory uORF :: PMID: 19372376 ##RefSeq-Attributes-END##

ATGGCAGCCC TGCTGAGACC CGCGCGTTGG CTGCTCGGGG CCGCGGCGGC CCCGCGCCTC 
CCGCTGTCCC TGCGCCTCCC TGCGGGCGTC CCGGGCCGGC TGTCCTCCGT CGTCCGGGTC 
GCGGCTGTTG GTAGCCGGCC GGCTGCAGGA GAGCGTCTGA GCCAAGCCAG ATTGTATGCC 
ATCGTTGCTG AGAAAAGGGA TCTTCAAGAG GAGCCTGCTC CTGTGAGAAA GAACAGCAGT 
CAATTTGACT GGGCTCTGAT GAGACTGGAT AATTCTGTCC GGAGAACAGG CCGCATCACA 
AAGGGGCTTC TGCAGAGAGT CTTTGAGAGC ACGTGTAGCT CAGGTAGCCC AGGGAGCAAT 
CAAGCTCTGC TTCTGCTGCG CAGCTGTGGC TCGCTCCTGC CCGAACTGAG TCTCGCCGAG 
AGGACAGAGT TTGCTCACAA GATCTGGGAC AAACTTCAGC AGTTAGGTGT CGTATATGAT 
GTCAGTCATT ACAATGCTTT ACTTAAAGTA TATCTTCAAA ATGAATACAA ATTTTCACCT 
ACTGACTTCC TGGCAAAGAT GGAGGGAGCA AACATCCAAC CAAATCGAGT AACATACCAG 
AGGCTGATAG CTGCCTACTG TAATGTTGGG GACATTGAAG GTGCCAGCAA GATCCTTGGA 
TTTATGAAAA CGAAAGACCT TCCGATCACA GAGGCCGTGT TCAGTGCTCT CGTCACAGGG 
CATGCGAGAG CTGGGGATAT GGAAAATGCA GAAAATATTC TCACAGTGAT GAAACAGGCC 
GGCATTGAGC CTGGCCCAGA CACGTATCTG GCCTTGTTGA ATGCACATGC TGAGAGGGGT 
GACATTGGCC AGGTTAGGCA GATTCTGGAG AAAGTGGAGA AGTCAGACCA TTACTTCATG 
GACCGCGACT TCTTGCAGGT TATTTTTAGC TTCAGTAAGG CTGGCTACCC TCAGTATGTC 
TCAGAAATAC TGGAGAAGAT TACCTATGAG AGACGGTCTA TTCCAGATGC AATGAACCTC 
ATTTTGTTTT TAGCCACTGA GAAGTTAGAA GACACTGCGT TCCAGGTTTT ATTGGCATTA 
CCCCTGTCCA AGGACGAGAG CTCCGATAAC TTTGGCAGTT TCTTTTTGCG GCACTGTGTG 
ACTCTGGATT TGCCCCCTGA GAAGCTGATA GACTACTGTC GGAGGCTGAG GGACGCCAAG 
CTGCACAGCT CCTCACTGCA GTTCACGCTG CACTGTGCTC TTCAAGCCAA TAGGACAGCT 
TTGGCAAAAG CAGTGATGGA GGCTTTGAGG GAAGAAGGGT TTCCTATCCG ACCGCACTAT 
TTCTGGCCGT TGCTTGCTGG GCATCAGAAA ACAAAAAATG TTCAAGGAAT AATAGATATC 
CTCAAAATAA TGAACAAAGT GGGAGTGGAT CCTGATCAGG AAACATATAT AAACTATGTG 
TTTCCGTGCT TTGATAGTGC ACAGTCAGTT CGAGCTGCTT TGCAGGAAAA TGAATGTCTC 
CTCGCAAGTA GTACCTTTGC TCAAGCTGAA GTGAAGAATG AAGCAATAAA TGGGAACTTA 
CAGAACATTT TGTCATTTTT GGAATCGAAT ACATTGCCTT TCTCGTTTAG TTCTTTGAGA 
AACAGCCTAA TCCTAGGCTT CAGGAGGTCG ATGAACATAG ATCTTTGGAG CAAGATAACA 
GAATTGTTGT ACAAGGATGA ACGCTATTGC TCAAAGCCTC CGGGACCAGC GGAAGCTGTT 
GGCTATTTTC TTTATAACTT GATTGACAGC ATGAGTGACT CAGAGGTACA GGCCAAGGAG 
GAGCGTTTGA GACAATACTT CCATCAGCTG CAGGAGATGA ATGTTAAAGT TCCTGAAAAC 
ATCTACAAAG GCATTTGTAA TTTGCTGAAT ACCTACCATG TTCCTGAATT GATTAAGGAT 
ATTAAGGTTC TGGTTGACAG AGAGAAGGTA GATTCTCAAA AAACTTCTCA AGTTACCTCA 
TCTGATTTGG AATCAACACT TGAGAAACTC AAAGCTGAAG GCCAACCTGT AGGATCTGCC 
CTGAAGCAGC TCCTGCTGCT GCTCTGCTCA GAGGAGAATA TGCAAAAGGC CCTTGAGGTG 
AAAGCAAAAT ATGAGTCAGA CATGGTTATT GGTGGCTATG CAGCATTAAT AAATTTGTGC 
TGTCGACATG ATAATGCAGA AGATGCGTGG AACTTGAAAC AAGAAGTTGA CCGCTTAGAT 
GCTTCGGCTA TTCTTGACAC TGCCAAGTAC GTAGCCCTTG TAAAAGTACT GGGAAAGCAC 
AGCAGACTCC AAGATGCTAT TAACATTCTA AAGGAGATGA AAGAGAAGGA TGTTGTTATC 
AAAGATGCAA CAGTCTTGTC CTTTTTCCAC ATCCTCAATG GTGCAGCTTT AAGAGGTGAA 
ATTGAAACAG TAAAACAGCT GCATGAAGCC ATCGTGACTC TTGGGTTGGC AAAGCCGTCC 
AGCAACATAA GCTTCCCGTT GGTCACTGTG CACCTGGAAA AGGGTGACTT ACCTGCTGCT 
CTTGAAGCCA GCATTGCCTG CCATAAAAAA TATAAAGTGT TACCCAGGAT TCATGATGTC 
TTATGTAAGC TAGTAGAGAA AGGCGAGACT GATTTGATCC AGAAAGCAAT GGACTTTGTG 
AGCCAAGAAC AAGGGGAGAT GACGATGCTC TACGACCTCT TCTTTGCTTT CCTGCAGACG 
GGGAATTACA AAGAAGCTAA GAAGATCATT GAGACTCCAG GCATTAGAGC TCGGCCTACA 
AGACTCCAGT GGTTTTGTGA TCGATGCATT GCCAGTAATC AGGTTGAAGC TCTTGAGAAG 
TTGGTAGAGC TGACTGAGAA GCTGTTTGAG TGTGACAGAG ACCAGATGTA CTACAACTTA 
CTGAAGCTAT ACAAAATAAG CAGTGACTGG CAAAGAGCGG ATGCTGCGTG GACCAAAATG 
CAAGAAGAGA ACATTATCCC TCGAGAGCGG ACACTGCGGC TCTTAGCCGA GATCTTGAAA 
ACCAGCAACC AGGAAGTTCC TTTCGACGTT CCGGAGTTGT GGTTTGGAGA TGACAGACCT 
TCCCTGAGTC CATCCTCACG CTCAGCAGGA GAGGACGTTA CTGAGAAGAC GTTGTTGTCT 
AACTGCAAAC TAAAGAAGAG TAAAGATGCA TATAATATCT TCCTTAAAGC CGAAAAGCAA 
AACGTTGTAT TTAGCAGTGA AACTTATAGC ACCTTGATAG GCTTGCTGCT GAGTAAGGAC 
GACTTCACCC AAGCAATGCA CGTGAAGGAT TTCGCTGAGA CCCACATCAA GGGCTTCACA 
CTGAACGATG CTGCCAACAG CCTCCTCATC ATAAGGCAAG TTAGGCGGGA TTATTTGAAA 
GGGGCTCTGG CAACTCTGAG AGCAGCCTTG GATTTGAAGC AGGTTCCGTC CCAGATCGCC 
GTGACCCGCC TCATCCAGGC GTTGGCCTTG AAGGGTGATG TGGAAAGCAT AGAGGCCATT 
CAGAGAATGG TGGCTGGACT TGACACGATT GGACTCTCAA AAATGGTTTT TATCAATAAC 
ATCGCTTTGG CCCAGATGAA GAATAATAAA CTTGATGCTG CCATAGAAAA CATTGAGCAC 
CTGCTTGCTT CCGAGAACCA AGCCATAGAA CCTCAGTACT TTGGCTTGTC GTATCTATTC 
AGAAAAGTGA TCGAAGAGCA GATGGAACCA GCGCTAGAGA AGTTAAGCAT CATGTCTGAG 
AGAATGGCGA ATCAGTTTGC ACTTTACAAG CCCGTCACTG ATCTATTCCT GCAGCTTGTG 
GATTCAGGCA AGGTGGATGA GGCCAGAGCT CTCTTAGAGA GATGCGGTGC CATTGCCGAG 
CAGAGCTCGC TTCTGTCGGT GTTCTGTCTG AGGACTTCTC AGAAACCGAA AAAGGCACCA 
GTTCTGAAGA CTTTGTTAGA ACTGATTCCT GAGTTACGTG ATAACGATAA AGTATATTCT 
TGCAGCATGA AAAGCTATGC CTTAGACAAA GATGTGGCCT CGGCTAAAGC ACTGTATGAG 
TATTTGACAG CCAAGAACTT GAAGCTAGAT GACCTGTTTC TCAAGCGCTA TGCAGCTTTG 
CTCAAGGATG TCGGCGAACC AGTCCCCTTC CCCGAGCCCC CTGAAAGCTT TGCATTTTAT 
ATAAAGCAAC TAAAGGAAGC AAGGGAAAGC CCTTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082509.2
CDS	274..4452
Translation	MAALLRPARWLLGAAAAPRLPLSLRLPAGVPGRLSSVVRVAAVGSRPAAGERLSQARLYAIVAEKRDLQEEPAPVRKNSSQFDWALMRLDNSVRRTGRITKGLLQRVFESTCSSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGVVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEGANIQPNRVTYQRLIAAYCNVGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKQAGIEPGPDTYLALLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITYERRSIPDAMNLILFLATEKLEDTAFQVLLALPLSKDESSDNFGSFFLRHCVTLDLPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGFPIRPHYFWPLLAGHQKTKNVQGIIDILKIMNKVGVDPDQETYINYVFPCFDSAQSVRAALQENECLLASSTFAQAEVKNEAINGNLQNILSFLESNTLPFSFSSLRNSLILGFRRSMNIDLWSKITELLYKDERYCSKPPGPAEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQKTSQVTSSDLESTLEKLKAEGQPVGSALKQLLLLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDAWNLKQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKGDLPAALEASIACHKKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVELTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFDVPELWFGDDRPSLSPSSRSAGEDVTEKTLLSNCKLKKSKDAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDFTQAMHVKDFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLDTIGLSKMVFINNIALAQMKNNKLDAAIENIEHLLASENQAIEPQYFGLSYLFRKVIEEQMEPALEKLSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKAPVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS

Target ORF information:

RefSeq Version	NM_028233.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine-rich PPR-motif containing (Lrpprc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028233.2

ORF Insert Sequence:

ATGGCAGCCC TGCTGAGACC CGCGCGTTGG CTGCTCGGGG CCGCGGCGGC CCCGCGCCTC 
CCGCTGTCCC TGCGCCTCCC TGCGGGCGTC CCGGGCCGGC TGTCCTCCGT CGTCCGGGTC 
GCGGCTGTTG GTAGCCGGCC GGCTGCAGGA GAGCGTCTGA GCCAAGCCAG ATTGTATGCC 
ATCGTTGCTG AGAAAAGGGA TCTTCAAGAG GAGCCTGCTC CTGTGAGAAA GAACAGCAGT 
CAATTTGACT GGGCTCTGAT GAGACTGGAT AATTCTGTCC GGAGAACAGG CCGCATCACA 
AAGGGGCTTC TGCAGAGAGT CTTTGAGAGC ACGTGTAGCT CAGGTAGCCC AGGGAGCAAT 
CAAGCTCTGC TTCTGCTGCG CAGCTGTGGC TCGCTCCTGC CCGAACTGAG TCTCGCCGAG 
AGGACAGAGT TTGCTCACAA GATCTGGGAC AAACTTCAGC AGTTAGGTGT CGTATATGAT 
GTCAGTCATT ACAATGCTTT ACTTAAAGTA TATCTTCAAA ATGAATACAA ATTTTCACCT 
ACTGACTTCC TGGCAAAGAT GGAGGGAGCA AACATCCAAC CAAATCGAGT AACATACCAG 
AGGCTGATAG CTGCCTACTG TAATGTTGGG GACATTGAAG GTGCCAGCAA GATCCTTGGA 
TTTATGAAAA CGAAAGACCT TCCGATCACA GAGGCCGTGT TCAGTGCTCT CGTCACAGGG 
CATGCGAGAG CTGGGGATAT GGAAAATGCA GAAAATATTC TCACAGTGAT GAAACAGGCC 
GGCATTGAGC CTGGCCCAGA CACGTATCTG GCCTTGTTGA ATGCACATGC TGAGAGGGGT 
GACATTGGCC AGGTTAGGCA GATTCTGGAG AAAGTGGAGA AGTCAGACCA TTACTTCATG 
GACCGCGACT TCTTGCAGGT TATTTTTAGC TTCAGTAAGG CTGGCTACCC TCAGTATGTC 
TCAGAAATAC TGGAGAAGAT TACCTATGAG AGACGGTCTA TTCCAGATGC AATGAACCTC 
ATTTTGTTTT TAGCCACTGA GAAGTTAGAA GACACTGCGT TCCAGGTTTT ATTGGCATTA 
CCCCTGTCCA AGGACGAGAG CTCCGATAAC TTTGGCAGTT TCTTTTTGCG GCACTGTGTG 
ACTCTGGATT TGCCCCCTGA GAAGCTGATA GACTACTGTC GGAGGCTGAG GGACGCCAAG 
CTGCACAGCT CCTCACTGCA GTTCACGCTG CACTGTGCTC TTCAAGCCAA TAGGACAGCT 
TTGGCAAAAG CAGTGATGGA GGCTTTGAGG GAAGAAGGGT TTCCTATCCG ACCGCACTAT 
TTCTGGCCGT TGCTTGCTGG GCATCAGAAA ACAAAAAATG TTCAAGGAAT AATAGATATC 
CTCAAAATAA TGAACAAAGT GGGAGTGGAT CCTGATCAGG AAACATATAT AAACTATGTG 
TTTCCGTGCT TTGATAGTGC ACAGTCAGTT CGAGCTGCTT TGCAGGAAAA TGAATGTCTC 
CTCGCAAGTA GTACCTTTGC TCAAGCTGAA GTGAAGAATG AAGCAATAAA TGGGAACTTA 
CAGAACATTT TGTCATTTTT GGAATCGAAT ACATTGCCTT TCTCGTTTAG TTCTTTGAGA 
AACAGCCTAA TCCTAGGCTT CAGGAGGTCG ATGAACATAG ATCTTTGGAG CAAGATAACA 
GAATTGTTGT ACAAGGATGA ACGCTATTGC TCAAAGCCTC CGGGACCAGC GGAAGCTGTT 
GGCTATTTTC TTTATAACTT GATTGACAGC ATGAGTGACT CAGAGGTACA GGCCAAGGAG 
GAGCGTTTGA GACAATACTT CCATCAGCTG CAGGAGATGA ATGTTAAAGT TCCTGAAAAC 
ATCTACAAAG GCATTTGTAA TTTGCTGAAT ACCTACCATG TTCCTGAATT GATTAAGGAT 
ATTAAGGTTC TGGTTGACAG AGAGAAGGTA GATTCTCAAA AAACTTCTCA AGTTACCTCA 
TCTGATTTGG AATCAACACT TGAGAAACTC AAAGCTGAAG GCCAACCTGT AGGATCTGCC 
CTGAAGCAGC TCCTGCTGCT GCTCTGCTCA GAGGAGAATA TGCAAAAGGC CCTTGAGGTG 
AAAGCAAAAT ATGAGTCAGA CATGGTTATT GGTGGCTATG CAGCATTAAT AAATTTGTGC 
TGTCGACATG ATAATGCAGA AGATGCGTGG AACTTGAAAC AAGAAGTTGA CCGCTTAGAT 
GCTTCGGCTA TTCTTGACAC TGCCAAGTAC GTAGCCCTTG TAAAAGTACT GGGAAAGCAC 
AGCAGACTCC AAGATGCTAT TAACATTCTA AAGGAGATGA AAGAGAAGGA TGTTGTTATC 
AAAGATGCAA CAGTCTTGTC CTTTTTCCAC ATCCTCAATG GTGCAGCTTT AAGAGGTGAA 
ATTGAAACAG TAAAACAGCT GCATGAAGCC ATCGTGACTC TTGGGTTGGC AAAGCCGTCC 
AGCAACATAA GCTTCCCGTT GGTCACTGTG CACCTGGAAA AGGGTGACTT ACCTGCTGCT 
CTTGAAGCCA GCATTGCCTG CCATAAAAAA TATAAAGTGT TACCCAGGAT TCATGATGTC 
TTATGTAAGC TAGTAGAGAA AGGCGAGACT GATTTGATCC AGAAAGCAAT GGACTTTGTG 
AGCCAAGAAC AAGGGGAGAT GACGATGCTC TACGACCTCT TCTTTGCTTT CCTGCAGACG 
GGGAATTACA AAGAAGCTAA GAAGATCATT GAGACTCCAG GCATTAGAGC TCGGCCTACA 
AGACTCCAGT GGTTTTGTGA TCGATGCATT GCCAGTAATC AGGTTGAAGC TCTTGAGAAG 
TTGGTAGAGC TGACTGAGAA GCTGTTTGAG TGTGACAGAG ACCAGATGTA CTACAACTTA 
CTGAAGCTAT ACAAAATAAG CAGTGACTGG CAAAGAGCGG ATGCTGCGTG GACCAAAATG 
CAAGAAGAGA ACATTATCCC TCGAGAGCGG ACACTGCGGC TCTTAGCCGA GATCTTGAAA 
ACCAGCAACC AGGAAGTTCC TTTCGACGTT CCGGAGTTGT GGTTTGGAGA TGACAGACCT 
TCCCTGAGTC CATCCTCACG CTCAGCAGGA GAGGACGTTA CTGAGAAGAC GTTGTTGTCT 
AACTGCAAAC TAAAGAAGAG TAAAGATGCA TATAATATCT TCCTTAAAGC CGAAAAGCAA 
AACGTTGTAT TTAGCAGTGA AACTTATAGC ACCTTGATAG GCTTGCTGCT GAGTAAGGAC 
GACTTCACCC AAGCAATGCA CGTGAAGGAT TTCGCTGAGA CCCACATCAA GGGCTTCACA 
CTGAACGATG CTGCCAACAG CCTCCTCATC ATAAGGCAAG TTAGGCGGGA TTATTTGAAA 
GGGGCTCTGG CAACTCTGAG AGCAGCCTTG GATTTGAAGC AGGTTCCGTC CCAGATCGCC 
GTGACCCGCC TCATCCAGGC GTTGGCCTTG AAGGGTGATG TGGAAAGCAT AGAGGCCATT 
CAGAGAATGG TGGCTGGACT TGACACGATT GGACTCTCAA AAATGGTTTT TATCAATAAC 
ATCGCTTTGG CCCAGATGAA GAATAATAAA CTTGATGCTG CCATAGAAAA CATTGAGCAC 
CTGCTTGCTT CCGAGAACCA AGCCATAGAA CCTCAGTACT TTGGCTTGTC GTATCTATTC 
AGAAAAGTGA TCGAAGAGCA GATGGAACCA GCGCTAGAGA AGTTAAGCAT CATGTCTGAG 
AGAATGGCGA ATCAGTTTGC ACTTTACAAG CCCGTCACTG ATCTATTCCT GCAGCTTGTG 
GATTCAGGCA AGGTGGATGA GGCCAGAGCT CTCTTAGAGA GATGCGGTGC CATTGCCGAG 
CAGAGCTCGC TTCTGTCGGT GTTCTGTCTG AGGACTTCTC AGAAACCGAA AAAGGCACCA 
GTTCTGAAGA CTTTGTTAGA ACTGATTCCT GAGTTACGTG ATAACGATAA AGTATATTCT 
TGCAGCATGA AAAGCTATGC CTTAGACAAA GATGTGGCCT CGGCTAAAGC ACTGTATGAG 
TATTTGACAG CCAAGAACTT GAAGCTAGAT GACCTGTTTC TCAAGCGCTA TGCAGCTTTG 
CTCAAGGATG TCGGCGAACC AGTCCCCTTC CCCGAGCCCC CTGAAAGCTT TGCATTTTAT 
ATAAAGCAAC TAAAGGAAGC AAGGGAAAGC CCTTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LRPPRC-mediated folding of the mitochondrial transcriptome.
Nature communications8(1)1532(2017 Nov)
Siira SJ,Sp?hr H,Shearwood AJ,Ruzzenente B,Larsson NG,Rackham O,Filipovska A

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals.
eLife6(2017 Nov)
K?hl I,Miranda M,Atanassov I,Kuznetsova I,Hinze Y,Mourier A,Filipovska A,Larsson NG

Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion.
Human molecular genetics26(16)3186-3201(2017 Aug)
Cuillerier A,Honarmand S,Cadete VJJ,Ruiz M,Forest A,Desch?nes S,Beauchamp C,,Charron G,Rioux JD,Des Rosiers C,Shoubridge EA,Burelle Y

An unexpected role for the transcriptional coactivator isoform NT-PGC-1? in the regulation of mitochondrial respiration in brown adipocytes.
The Journal of biological chemistry292(24)9958-9966(2017 06)
Chang JS,Ha K

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Lrpprc cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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