Lsm11 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsm11
Entrez Gene ID	72290
Full Name	U7 snRNP-specific Sm-like protein LSM11
Synonyms	2210404M20Rik,AV079530
General protein information	Preferred Names U7 snRNP-specific Sm-like protein LSM11 Names U7 snRNA-associated Sm-like protein LSm11
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B1.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_028185.2	NP_082461.1	U7 snRNA-associated Sm-like protein LSm11
XM_011249271.2	XP_011247573.1	U7 snRNA-associated Sm-like protein LSm11 isoform X1
XM_011249271.3	XP_011247573.1	U7 snRNA-associated Sm-like protein LSm11 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LSM11	XP_001138531.1
Rattus norvegicus (Norway rat)	Lsm11	NP_001166855.1
Xenopus tropicalis (tropical clawed frog)	lsm11	XP_002939655.2
Homo sapiens (human)	LSM11	NP_775762.1
	LOC100429445	XP_002804651.1
Mus musculus (house mouse)	Lsm11	NP_082461.1
Gallus gallus (chicken)	LSM11	XP_414562.3
Bos taurus (cattle)	LSM11	XP_002707877.1

Gene Ontology
Bibliography

Related articles in PubMed

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.
Ruepp MD, Vivarelli S, Pillai RS, Kleinschmidt N, Azzouz TN, Barabino SM, Sch?mperli D
Nucleic acids research38(21)7637-50(2010 Nov)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Yang XC, Torres MP, Marzluff WF, Dominski Z
Molecular and cellular biology29(15)4045-56(2009 Aug)

Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.
Azzouz TN, Pillai RS, D?pp C, Chari A, Meister G, Kambach C, Fischer U, Sch?mperli D
The Journal of biological chemistry280(41)34435-40(2005 Oct)

U7 snRNP-specific Lsm11 protein: dual binding contacts with the 100 kDa zinc finger processing factor (ZFP100) and a ZFP100-independent function in histone RNA 3' end processing.
Azzouz TN, Gruber A, Sch?mperli D
Nucleic acids research33(7)2106-17(2005)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Specifies the assembly of the U7 Sm core, also fulfills an important role in U7 snRNP-mediated histone mRNA processing.
Title: Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

The following Lsm11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsm11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu70892	XM_011249271.3 Latest version!	Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu15185	NM_028185.2 Latest version!	Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
View Old Accession Versions >>
OMu70892	XM_011249271.2	Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsm11 ( XM_011249271.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011247573.1 Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70892
Clone ID Related Accession (Same CDS sequence)	XM_011249271.2 , XM_011249271.3
Accession Version	XM_011249271.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	U7 snRNA-associated Sm-like protein LSm11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011249271.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCTT GTACGCACCT 
CGCCTGCCGC CCATTCCCTA CCCCAACGCG CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGGGCTC GGGGCACGGG GGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA GCTCGTCCAG GGCCCGTCGC 
CGCGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGAGCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ATGTGCTTAC GCGGATGCCT TTGCATGAAG GTAGCCCTCT GGGTGAACTG 
CACCGCTGCA TCCGAGAGGG AGTCAAGGTG AACGTTCACA TCCGCACCTT CAAGGGACTC 
CGCGGTGTCT GCACTGGCTT CCTCGTCGCC TTCGACAAGT TCTGGAATAT GGCCCTCACT 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGAAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTTCAAG ATTCCTCCAA AAAGGAAGCG 
GATTCCAAAT CTGCAGTTGA GGACTCCACC CTGTCTCGAT ACTCCCAAAC ATCTACTTGG 
AAGGTGGCTT CGGTATGGGG ACGAGGGGAC ACTGACCGGA GCTCACACAG GCGCTCCCGC 
TCCGTCCCTT CTTCCCTGCA GGCATCTGCA AGGGAGGAGT CCAGGTCTGA GCTGTCAGGG 
AGGACTACAC GGACAGAAGG GTCCAGTGTG GGAGGTACCT TCTCCAGGGC CACCACCCTT 
TCACGGGGCC AGTCCCGTAA GAAAAAGCGA AAGCCCAAGG TGGATTACCA GCAGCCTTCA 
TCAGAGGCTG TTTTCCATGA TCTGGTCCTT CCTCCAGAAA GAAGCAGGAG TTCTCAGAGG 
AACACGTCCT TCCATCCAGG AGAAAGTGAC TTTCTGTCTG CGGCTGCTCC ACATCCCGGG 
CCTGCTTTTC AAGGGTATCT GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011247573.1
CDS	85..1251
Translation	MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAGSSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGARRQGPGRSKKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEADSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRSSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQPSSEAVFHDLVLPPERSRSSQRNTSFHPGESDFLSAAAPHPGPAFQGYLF

Target ORF information:

RefSeq Version	XM_011249271.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011249271.3

ORF Insert Sequence:

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCTT GTACGCACCT 
CGCCTGCCGC CCATTCCCTA CCCCAACGCG CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGGGCTC GGGGCACGGG GGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA GCTCGTCCAG GGCCCGTCGC 
CGCGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGAGCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ATGTGCTTAC GCGGATGCCT TTGCATGAAG GTAGCCCTCT GGGTGAACTG 
CACCGCTGCA TCCGAGAGGG AGTCAAGGTG AACGTTCACA TCCGCACCTT CAAGGGACTC 
CGCGGTGTCT GCACTGGCTT CCTCGTCGCC TTCGACAAGT TCTGGAATAT GGCCCTCACT 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGAAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTTCAAG ATTCCTCCAA AAAGGAAGCG 
GATTCCAAAT CTGCAGTTGA GGACTCCACC CTGTCTCGAT ACTCCCAAAC ATCTACTTGG 
AAGGTGGCTT CGGTATGGGG ACGAGGGGAC ACTGACCGGA GCTCACACAG GCGCTCCCGC 
TCCGTCCCTT CTTCCCTGCA GGCATCTGCA AGGGAGGAGT CCAGGTCTGA GCTGTCAGGG 
AGGACTACAC GGACAGAAGG GTCCAGTGTG GGAGGTACCT TCTCCAGGGC CACCACCCTT 
TCACGGGGCC AGTCCCGTAA GAAAAAGCGA AAGCCCAAGG TGGATTACCA GCAGCCTTCA 
TCAGAGGCTG TTTTCCATGA TCTGGTCCTT CCTCCAGAAA GAAGCAGGAG TTCTCAGAGG 
AACACGTCCT TCCATCCAGG AGAAAGTGAC TTTCTGTCTG CGGCTGCTCC ACATCCCGGG 
CCTGCTTTTC AAGGGTATCT GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm11 ( NM_028185.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082461.1 Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), mRNA.

Price & Availability↑

CloneID	OMu15185
Clone ID Related Accession (Same CDS sequence)	NM_028185.2
Accession Version	NM_028185.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	U7 snRNA-associated Sm-like protein LSm11
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB650044.1, AK143661.1 and AL645948.10. On Sep 23, 2006 this sequence version replaced NM_028185.1. ##Evidence-Data-START## Transcript exon combination :: AK143661.1, BC094286.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCTT GTACGCACCT 
CGCCTGCCGC CCATTCCCTA CCCCAACGCG CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGGGCTC GGGGCACGGG GGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA GCTCGTCCAG GGCCCGTCGC 
CGCGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGAGCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ATGTGCTTAC GCGGATGCCT TTGCATGAAG GTAGCCCTCT GGGTGAACTG 
CACCGCTGCA TCCGAGAGGG AGTCAAGGTG AACGTTCACA TCCGCACCTT CAAGGGACTC 
CGCGGTGTCT GCACTGGCTT CCTCGTCGCC TTCGACAAGT TCTGGAATAT GGCCCTCACT 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGAAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTTCAAG ATTCCTCCAA AAAGGAAGCG 
GATTCCAAAT CTGCAGTTGA GGACTCCACC CTGTCTCGAT ACTCCCAAAC ATCTACTTGG 
AAGGTGGCTT CGGTATGGGG ACGAGGGGAC ACTGACCGGA GCTCACACAG GCGCTCCCGC 
TCCGTCCCTT CTTCCCTGCA GGCATCTGCA AGGGAGGAGT CCAGGTCTGA GCTGTCAGGG 
AGGACTACAC GGACAGAAGG GTCCAGTGTG GGAGGTACCT TCTCCAGGGC CACCACCCTT 
TCACGGGGCC AGTCCCGTAA GAAAAAGCGA AAGCCCAAGG TGGATTACCA GCAGGTATTC 
ACTCGGCACA TAAATCAGAT TTTCATTCGA GGCGAGAATG TCCTGCTGGT CCATCTGGCC 
CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082461.1
CDS	24..1109
Translation	MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAGSSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGARRQGPGRSKKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEADSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRSSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ

Target ORF information:

RefSeq Version	NM_028185.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028185.2

ORF Insert Sequence:

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCTT GTACGCACCT 
CGCCTGCCGC CCATTCCCTA CCCCAACGCG CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGGGCTC GGGGCACGGG GGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA GCTCGTCCAG GGCCCGTCGC 
CGCGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGAGCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ATGTGCTTAC GCGGATGCCT TTGCATGAAG GTAGCCCTCT GGGTGAACTG 
CACCGCTGCA TCCGAGAGGG AGTCAAGGTG AACGTTCACA TCCGCACCTT CAAGGGACTC 
CGCGGTGTCT GCACTGGCTT CCTCGTCGCC TTCGACAAGT TCTGGAATAT GGCCCTCACT 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGAAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTTCAAG ATTCCTCCAA AAAGGAAGCG 
GATTCCAAAT CTGCAGTTGA GGACTCCACC CTGTCTCGAT ACTCCCAAAC ATCTACTTGG 
AAGGTGGCTT CGGTATGGGG ACGAGGGGAC ACTGACCGGA GCTCACACAG GCGCTCCCGC 
TCCGTCCCTT CTTCCCTGCA GGCATCTGCA AGGGAGGAGT CCAGGTCTGA GCTGTCAGGG 
AGGACTACAC GGACAGAAGG GTCCAGTGTG GGAGGTACCT TCTCCAGGGC CACCACCCTT 
TCACGGGGCC AGTCCCGTAA GAAAAAGCGA AAGCCCAAGG TGGATTACCA GCAGGTATTC 
ACTCGGCACA TAAATCAGAT TTTCATTCGA GGCGAGAATG TCCTGCTGGT CCATCTGGCC 
CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm11 ( XM_011249271.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011247573.1 Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70892
Clone ID Related Accession (Same CDS sequence)	XM_011249271.2 , XM_011249271.3
Accession Version	XM_011249271.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	U7 snRNA-associated Sm-like protein LSm11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011249271.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCTT GTACGCACCT 
CGCCTGCCGC CCATTCCCTA CCCCAACGCG CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGGGCTC GGGGCACGGG GGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA GCTCGTCCAG GGCCCGTCGC 
CGCGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGAGCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ATGTGCTTAC GCGGATGCCT TTGCATGAAG GTAGCCCTCT GGGTGAACTG 
CACCGCTGCA TCCGAGAGGG AGTCAAGGTG AACGTTCACA TCCGCACCTT CAAGGGACTC 
CGCGGTGTCT GCACTGGCTT CCTCGTCGCC TTCGACAAGT TCTGGAATAT GGCCCTCACT 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGAAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTTCAAG ATTCCTCCAA AAAGGAAGCG 
GATTCCAAAT CTGCAGTTGA GGACTCCACC CTGTCTCGAT ACTCCCAAAC ATCTACTTGG 
AAGGTGGCTT CGGTATGGGG ACGAGGGGAC ACTGACCGGA GCTCACACAG GCGCTCCCGC 
TCCGTCCCTT CTTCCCTGCA GGCATCTGCA AGGGAGGAGT CCAGGTCTGA GCTGTCAGGG 
AGGACTACAC GGACAGAAGG GTCCAGTGTG GGAGGTACCT TCTCCAGGGC CACCACCCTT 
TCACGGGGCC AGTCCCGTAA GAAAAAGCGA AAGCCCAAGG TGGATTACCA GCAGCCTTCA 
TCAGAGGCTG TTTTCCATGA TCTGGTCCTT CCTCCAGAAA GAAGCAGGAG TTCTCAGAGG 
AACACGTCCT TCCATCCAGG AGAAAGTGAC TTTCTGTCTG CGGCTGCTCC ACATCCCGGG 
CCTGCTTTTC AAGGGTATCT GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011247573.1
CDS	89..1255
Translation	MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAGSSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGARRQGPGRSKKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEADSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRSSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQPSSEAVFHDLVLPPERSRSSQRNTSFHPGESDFLSAAAPHPGPAFQGYLF

Target ORF information:

RefSeq Version	XM_011249271.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus U7 snRNP-specific Sm-like protein LSM11 (Lsm11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011249271.2

ORF Insert Sequence:

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCTT GTACGCACCT 
CGCCTGCCGC CCATTCCCTA CCCCAACGCG CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGGGCTC GGGGCACGGG GGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA GCTCGTCCAG GGCCCGTCGC 
CGCGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGAGCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ATGTGCTTAC GCGGATGCCT TTGCATGAAG GTAGCCCTCT GGGTGAACTG 
CACCGCTGCA TCCGAGAGGG AGTCAAGGTG AACGTTCACA TCCGCACCTT CAAGGGACTC 
CGCGGTGTCT GCACTGGCTT CCTCGTCGCC TTCGACAAGT TCTGGAATAT GGCCCTCACT 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGAAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTTCAAG ATTCCTCCAA AAAGGAAGCG 
GATTCCAAAT CTGCAGTTGA GGACTCCACC CTGTCTCGAT ACTCCCAAAC ATCTACTTGG 
AAGGTGGCTT CGGTATGGGG ACGAGGGGAC ACTGACCGGA GCTCACACAG GCGCTCCCGC 
TCCGTCCCTT CTTCCCTGCA GGCATCTGCA AGGGAGGAGT CCAGGTCTGA GCTGTCAGGG 
AGGACTACAC GGACAGAAGG GTCCAGTGTG GGAGGTACCT TCTCCAGGGC CACCACCCTT 
TCACGGGGCC AGTCCCGTAA GAAAAAGCGA AAGCCCAAGG TGGATTACCA GCAGCCTTCA 
TCAGAGGCTG TTTTCCATGA TCTGGTCCTT CCTCCAGAAA GAAGCAGGAG TTCTCAGAGG 
AACACGTCCT TCCATCCAGG AGAAAGTGAC TTTCTGTCTG CGGCTGCTCC ACATCCCGGG 
CCTGCTTTTC AAGGGTATCT GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.
Nucleic acids research38(21)7637-50(2010 Nov)
Ruepp MD,Vivarelli S,Pillai RS,Kleinschmidt N,Azzouz TN,Barabino SM,Sch?mperli D

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Molecular and cellular biology29(15)4045-56(2009 Aug)
Yang XC,Torres MP,Marzluff WF,Dominski Z

Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.
The Journal of biological chemistry280(41)34435-40(2005 Oct)
Azzouz TN,Pillai RS,D?pp C,Chari A,Meister G,Kambach C,Fischer U,Sch?mperli D

U7 snRNP-specific Lsm11 protein: dual binding contacts with the 100 kDa zinc finger processing factor (ZFP100) and a ZFP100-independent function in histone RNA 3' end processing.
Nucleic acids research33(7)2106-17(2005)
Azzouz TN,Gruber A,Sch?mperli D

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Lsm11 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

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ORF Insert Sequence:

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ORF Insert Sequence:

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ORF Insert Sequence:

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