Mtrex cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mtrex
Entrez Gene ID	72198
Full Name	superkiller viralicidic activity 2-like 2 (S. cerevisiae)
Synonyms	2610528A15Rik,mKIAA0052
General protein information	Preferred Names superkiller viralicidic activity 2-like 2 (S. cerevisiae) Names superkiller viralicidic activity 2-like 2 ATP-dependent helicase SKIV2L2 TRAMP-like complex helicase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 D2.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_028151.2	NP_082427.1	exosome RNA helicase MTR4

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SKIV2L2	XP_849676.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009600	XP_318627.4
Homo sapiens (human)	SKIV2L2	NP_056175.3
Rattus norvegicus (Norway rat)	Skiv2l2	NP_001029265.1
Caenorhabditis elegans (roundworm)	mtr-4	NP_501757.1
Kluyveromyces lactis	KLLA0F01364g	XP_455141.1
Neurospora crassa	NCU03363	XP_956298.1
Pan troglodytes (chimpanzee)	SKIV2L2	XP_001145794.1
Schizosaccharomyces pombe (fission yeast)	mtr4	NP_593302.1
Arabidopsis thaliana (thale cress)	AT1G59760	NP_176185.1
Xenopus tropicalis (tropical clawed frog)	skiv2l2	XP_002941157.1
Saccharomyces cerevisiae (baker's yeast)	MTR4	NP_012485.1
	LOC706419	XP_002808474.1
Mus musculus (house mouse)	Skiv2l2	NP_082427.1
Gallus gallus (chicken)	SKIV2L2	NP_001012962.1
Danio rerio (zebrafish)	skiv2l2	NP_999933.1
Drosophila melanogaster (fruit fly)	l(2)35Df	NP_524929.1
Eremothecium gossypii	AGOS_AEL181C	NP_984680.2
Magnaporthe oryzae (rice blast fungus)	MGG_03931	XP_003719933.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of the RNA helicase SKIV2L2 impairs mitotic progression and replication-dependent histone mRNA turnover in murine cell lines.
Onderak AM, Anderson JT
RNA (New York, N.Y.)23(6)910-926(2017 06)

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.
Lim J, Giri PK, Kazadi D, Laffleur B, Zhang W, Grinstein V, Pefanis E, Brown LM, Ladewig E, Martin O, Chen Y, Rabadan R, Boyer F, Rothschild G, Cogn? M, Pinaud E, Deng H, Basu U
Cell169(3)523-537.e15(2017 Apr)

Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.
Xing J, Weng L, Yuan B, Wang Z, Jia L, Jin R, Lu H, Li XC, Liu YJ, Zhang Z
Nature immunology17(12)1373-1380(2016 Dec)

Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4.
Dorweiler JE, Ni T, Zhu J, Munroe SH, Anderson JT
PloS one9(6)e99430(2014)

Localization of a novel RNA-binding protein, SKIV2L2, to the nucleus in the round spermatids of mice.
Osman BA, Kawashima A, Tamba M, Satoh E, Kato Y, Iki A, Konishi K, Matsuda M, Okamura N
The Journal of reproduction and development57(4)457-67(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Skiv2l2 knockdown cells accumulated replication-dependent histone mRNAs, among other RNAs, that could impede mitotic progression and indirectly trigger differentiation.
Title: Loss of the RNA helicase SKIV2L2 impairs mitotic progression and replication-dependent histone mRNA turnover in murine cell lines.

Study reports that the noncoding RNA processing activity of RNA exosome, a 3'-5' RNA exonuclease, controls sense and antisense strand DNA mutagenesis, and prevents an increased asymmetric mutagenesis burden using a mechanism that relies on the unexpected DNA/RNA hybrid unwinding activities of the Mtr4 and senataxin RNA helicases.
Title: Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.

Results identify novel role for Mtr4 in targeting the 5' leader sequences of microRNAs for degradation.
Title: Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4.

SKIV2L2 is an RNA-binding protein localized to the nucleus in the round spermatids of mice
Title: Localization of a novel RNA-binding protein, SKIV2L2, to the nucleus in the round spermatids of mice.

The following Mtrex gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mtrex cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15840	NM_028151.2 Latest version!	Mus musculus Mtr4 exosome RNA helicase (Mtrex), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$615.30 $879.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mtrex ( NM_028151.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082427.1 Mus musculus Mtr4 exosome RNA helicase (Mtrex), mRNA.

Price & Availability↑

CloneID	OMu15840
Clone ID Related Accession (Same CDS sequence)	NM_028151.2
Accession Version	NM_028151.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3123bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	exosome RNA helicase MTR4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC165265.2. On Nov 17, 2006 this sequence version replaced NM_028151.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK012158.1, BC029230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGATG CTTTCGGGGA TGAGCTTTTC AGCGTTTTCG AGGATGATTC GACCTCTGCA 
GCAGGAGCCA AGAAAGACAA AGAGAAAGAG AAATGGAAGG GGCCACCAGG GTCTGCAGAC 
AAGGCCGGGA AACGACTGGA TACCAAATTA CAATCAGAGT CAGCCAGTGG GGGGAAAAAC 
AAAAGAGATC TAGATGTTGA AGGCACTGAT GAACCTATTT TTGGCAAGAA GCCGAGAATA 
GAAGACTCAA TTAATGAAGA TTTAAGCCTG GCGGACCTGA TGCCCAGAGT CAAGGTACAG 
TCAGTGGAAA CAGTTGAAGG CTGCACACAT GAGGTCGCTC TTCCTGCAGA TGAGGATTAT 
ATACCACTTA AACCTCGAGT TGGGAAGGCA GCAAAGGAAT ACCCATTCAT TCTTGATGCT 
TTCCAAAGAG AAGCCATTCA GTGTGTTGAT AATAACCAGT CTGTGCTAGT ATCTGCTCAT 
ACGTCAGCAG GGAAGACCGT GTGTGCCGAG TATGCTATTG CATTGGCTTT AAGAGAAAAA 
CAGCGTGTAA TATTTACCAG CCCTATTAAG GCTCTAAGTA ATCAGAAATA CCGTGAAATG 
TATGAAGAAT TTCAAGATGT GGGGCTGATG ACGGGAGATG TTACTATTAA TCCCACAGCA 
TCTTGTCTCG TTATGACTAC AGAGATTTTG AGAAGTATGC TGTATAGAGG CTCTGAAGTT 
ATGCGAGAAG TTGCTTGGGT CATATTTGAT GAAATTCATT ACATGAGAGA TTCAGAGCGT 
GGTGTAGTAT GGGAAGAAAC TATTATTTTG CTTCCAGATA ATGTTCACTA TGTCTTTCTT 
TCGGCTACTA TTCCAAATGC TCGACAGTTT GCTGAATGGA TTTGTCACCT ACATAAACAG 
CCCTGTCATG TTATTTACAC TGATTATCGA CCCACTCCAC TGCAACACTA CATATTTCCA 
GCAGGGGGAG ATGGCCTTCA CCTGGTGGTT GATGAAAATG GTGACTTCAG AGAAGATAAT 
TTTAACACTG CAATGCAAGT GCTGCGGGAT GCAGGTGATT TGGCCAAAGG AGACCAGAAG 
GGACGGAAAG GAGGAACAAA AGGTCCATCA AATGTGTTCA AGATTGTGAA GATGATTATG 
GAGAGAAATT TCCAGCCTGT GATCATCTTC AGTTTCAGTA AGAAGGACTG TGAAGCATAT 
GCTCTTCAGA TGACGAAGCT AGACTTCAAC ACAGATGAAG AAAAGAAGAT GGTTGAAGAA 
GTTTTCAATA ATGCAATTGA CTGCTTGTCT GATGAAGATA AAAAGCTCCC TCAGGTTGAA 
CATGTGCTTC CACTTTTGAA GCGGGGGATT GGTATTCACC ATGGTGGCTT ACTTCCTATT 
TTGAAAGAAA CTATAGAAAT TCTCTTTTCT GAAGGATTGA TAAAGGCTTT ATTTGCCACA 
GAGACTTTTG CTATGGGAAT TAACATGCCA GCTAGAACTG TTTTATTTAC AAATGCCCGT 
AAATATGACG GAAAGGACTT CAGATGGATT TCCTCTGGCG AGTACATCCA GATGTCTGGT 
CGCGCAGGAA GGAGAGGCAT GGACGACAGA GGGATTGTGA TTCTTATGGT AGACGAGAAG 
ATGAGCCCAA CTATTGGAAA GCAGCTGCTT AAGGGGTCAG CTGATCCTCT GAACAGTGCT 
TTCCATCTGA CCTATAACAT GGTTTTGAAC TTACTAAGAG TAGAAGAAAT TAACCCCGAG 
TACATGCTTG AAAAATCCTT CTACCAGTTT CAGCATTATA GAGCAATTCC AGGGGTCGTA 
GAAAAGGTAA AGAACTCAGA AGAGCAGTAT AATAAAATAG TCATTCCCAA TGAAGAAAAT 
GTGGTCATCT ATTACAAGAT TAGACAGCAA CTTGCCAAGC TGGGAAAAGA GATTGAAGAA 
TATATTCATA AACCAAAGTA CTGCTTACCC TTTCTACAGC CAGGCCGTTT GGTAAAGGTG 
AAAAATGAAG GCGATGATTT CGGCTGGGGA GTAGTAGTGA ACTTCTCAAA AAAGTCAAAT 
GTCAAGCCCA ATTCTGGCGA ACTGGATCCC TTGTATGTGG TGGAAGTCCT CCTGCGCTGT 
AGCAAGGAAA GCCTGAAGAA CTCAGCCACC GAGGCAGCAA AGCCAGCGAA GCCAGACGAG 
AAAGGGGAGA TGCAGGTTGT TCCAGTTTTG GTGCATCTCC TGTCTGCCAT CAGCACTGTC 
AGGCTCTATA TTCCAAAAGA CCTTCGACCT GTGGACAACA GACAGAGTGT CTTAAAATCC 
ATACAGGAAG TTCAAAGGCG CTTTCCCGAC GGCGTTCCTC TGTTAGATCC GATCGATGAT 
ATGGGCATCC AAGATCAAGG ACTGAAGAAA GTCATCCAGA AAGTAGAGGC CTTTGAGCAT 
CGCATGTACT CACACCCACT CCACAATGAT CCTAACTTGG AAACTGTTTA TACACTGTGT 
GAAAGAAAGG CCCAGATTGC ACTAGATATC AAGTCTGCAA AGAGAGAACT GAAGAAGGCA 
AGAACTGTTC TGCAAATGGA CGAGCTCAAA TGCCGCAAGC GCGTGCTGAG ACGGCTGGGC 
TTTGCGACAT CGTCGGATGT CATAGAGATG AAAGGACGGG TGGCTTGTGA AATAAGCAGT 
GCGGACGAGC TCCTTCTAAC GGAGATGATG TTCAATGGGC TTTTCAATGA CCTTTCTTCA 
GAGCAGGCAA CCGCACTGTT AAGCTGTTTT GTGTTTCAAG AGAATTCTAG TGAGATGCCC 
AAACTAACAG AGCAGTTAGC TGGACCACTC CGACAAATGC AGGAATGTGC TAAAAGGATT 
GCAAAAGTTT CAGCAGAGGC AAAGCTGGAG ATTGATGAAG AAACTTACCT AAGCTCATTC 
AAGCCTCACC TGATGGATGT GGTGTATACC TGGGCAACTG GGGCCACATT TGCCCATATC 
TGCAAAATGA CAGATGTTTT CGAAGGCAGT ATAATTCGTT GTATGAGGCG TCTGGAAGAA 
CTGCTTCGAC AGATGTGTCA AGCAGCAAAA GCCATTGGAA ACACAGAGCT GGAGAACAAA 
TTTGCTGAAG GAATTACCAA AATCAAGAGG GATATTGTAT TTGCTGCCAG CCTCTACTTA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082427.1
CDS	24..3146
Translation	MADAFGDELFSVFEDDSTSAAGAKKDKEKEKWKGPPGSADKAGKRLDTKLQSESASGGKNKRDLDVEGTDEPIFGKKPRIEDSINEDLSLADLMPRVKVQSVETVEGCTHEVALPADEDYIPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQSVLKSIQEVQRRFPDGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCERKAQIALDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL

Target ORF information:

RefSeq Version	NM_028151.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus Mtr4 exosome RNA helicase (Mtrex), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028151.2

ORF Insert Sequence:

ATGGCGGATG CTTTCGGGGA TGAGCTTTTC AGCGTTTTCG AGGATGATTC GACCTCTGCA 
GCAGGAGCCA AGAAAGACAA AGAGAAAGAG AAATGGAAGG GGCCACCAGG GTCTGCAGAC 
AAGGCCGGGA AACGACTGGA TACCAAATTA CAATCAGAGT CAGCCAGTGG GGGGAAAAAC 
AAAAGAGATC TAGATGTTGA AGGCACTGAT GAACCTATTT TTGGCAAGAA GCCGAGAATA 
GAAGACTCAA TTAATGAAGA TTTAAGCCTG GCGGACCTGA TGCCCAGAGT CAAGGTACAG 
TCAGTGGAAA CAGTTGAAGG CTGCACACAT GAGGTCGCTC TTCCTGCAGA TGAGGATTAT 
ATACCACTTA AACCTCGAGT TGGGAAGGCA GCAAAGGAAT ACCCATTCAT TCTTGATGCT 
TTCCAAAGAG AAGCCATTCA GTGTGTTGAT AATAACCAGT CTGTGCTAGT ATCTGCTCAT 
ACGTCAGCAG GGAAGACCGT GTGTGCCGAG TATGCTATTG CATTGGCTTT AAGAGAAAAA 
CAGCGTGTAA TATTTACCAG CCCTATTAAG GCTCTAAGTA ATCAGAAATA CCGTGAAATG 
TATGAAGAAT TTCAAGATGT GGGGCTGATG ACGGGAGATG TTACTATTAA TCCCACAGCA 
TCTTGTCTCG TTATGACTAC AGAGATTTTG AGAAGTATGC TGTATAGAGG CTCTGAAGTT 
ATGCGAGAAG TTGCTTGGGT CATATTTGAT GAAATTCATT ACATGAGAGA TTCAGAGCGT 
GGTGTAGTAT GGGAAGAAAC TATTATTTTG CTTCCAGATA ATGTTCACTA TGTCTTTCTT 
TCGGCTACTA TTCCAAATGC TCGACAGTTT GCTGAATGGA TTTGTCACCT ACATAAACAG 
CCCTGTCATG TTATTTACAC TGATTATCGA CCCACTCCAC TGCAACACTA CATATTTCCA 
GCAGGGGGAG ATGGCCTTCA CCTGGTGGTT GATGAAAATG GTGACTTCAG AGAAGATAAT 
TTTAACACTG CAATGCAAGT GCTGCGGGAT GCAGGTGATT TGGCCAAAGG AGACCAGAAG 
GGACGGAAAG GAGGAACAAA AGGTCCATCA AATGTGTTCA AGATTGTGAA GATGATTATG 
GAGAGAAATT TCCAGCCTGT GATCATCTTC AGTTTCAGTA AGAAGGACTG TGAAGCATAT 
GCTCTTCAGA TGACGAAGCT AGACTTCAAC ACAGATGAAG AAAAGAAGAT GGTTGAAGAA 
GTTTTCAATA ATGCAATTGA CTGCTTGTCT GATGAAGATA AAAAGCTCCC TCAGGTTGAA 
CATGTGCTTC CACTTTTGAA GCGGGGGATT GGTATTCACC ATGGTGGCTT ACTTCCTATT 
TTGAAAGAAA CTATAGAAAT TCTCTTTTCT GAAGGATTGA TAAAGGCTTT ATTTGCCACA 
GAGACTTTTG CTATGGGAAT TAACATGCCA GCTAGAACTG TTTTATTTAC AAATGCCCGT 
AAATATGACG GAAAGGACTT CAGATGGATT TCCTCTGGCG AGTACATCCA GATGTCTGGT 
CGCGCAGGAA GGAGAGGCAT GGACGACAGA GGGATTGTGA TTCTTATGGT AGACGAGAAG 
ATGAGCCCAA CTATTGGAAA GCAGCTGCTT AAGGGGTCAG CTGATCCTCT GAACAGTGCT 
TTCCATCTGA CCTATAACAT GGTTTTGAAC TTACTAAGAG TAGAAGAAAT TAACCCCGAG 
TACATGCTTG AAAAATCCTT CTACCAGTTT CAGCATTATA GAGCAATTCC AGGGGTCGTA 
GAAAAGGTAA AGAACTCAGA AGAGCAGTAT AATAAAATAG TCATTCCCAA TGAAGAAAAT 
GTGGTCATCT ATTACAAGAT TAGACAGCAA CTTGCCAAGC TGGGAAAAGA GATTGAAGAA 
TATATTCATA AACCAAAGTA CTGCTTACCC TTTCTACAGC CAGGCCGTTT GGTAAAGGTG 
AAAAATGAAG GCGATGATTT CGGCTGGGGA GTAGTAGTGA ACTTCTCAAA AAAGTCAAAT 
GTCAAGCCCA ATTCTGGCGA ACTGGATCCC TTGTATGTGG TGGAAGTCCT CCTGCGCTGT 
AGCAAGGAAA GCCTGAAGAA CTCAGCCACC GAGGCAGCAA AGCCAGCGAA GCCAGACGAG 
AAAGGGGAGA TGCAGGTTGT TCCAGTTTTG GTGCATCTCC TGTCTGCCAT CAGCACTGTC 
AGGCTCTATA TTCCAAAAGA CCTTCGACCT GTGGACAACA GACAGAGTGT CTTAAAATCC 
ATACAGGAAG TTCAAAGGCG CTTTCCCGAC GGCGTTCCTC TGTTAGATCC GATCGATGAT 
ATGGGCATCC AAGATCAAGG ACTGAAGAAA GTCATCCAGA AAGTAGAGGC CTTTGAGCAT 
CGCATGTACT CACACCCACT CCACAATGAT CCTAACTTGG AAACTGTTTA TACACTGTGT 
GAAAGAAAGG CCCAGATTGC ACTAGATATC AAGTCTGCAA AGAGAGAACT GAAGAAGGCA 
AGAACTGTTC TGCAAATGGA CGAGCTCAAA TGCCGCAAGC GCGTGCTGAG ACGGCTGGGC 
TTTGCGACAT CGTCGGATGT CATAGAGATG AAAGGACGGG TGGCTTGTGA AATAAGCAGT 
GCGGACGAGC TCCTTCTAAC GGAGATGATG TTCAATGGGC TTTTCAATGA CCTTTCTTCA 
GAGCAGGCAA CCGCACTGTT AAGCTGTTTT GTGTTTCAAG AGAATTCTAG TGAGATGCCC 
AAACTAACAG AGCAGTTAGC TGGACCACTC CGACAAATGC AGGAATGTGC TAAAAGGATT 
GCAAAAGTTT CAGCAGAGGC AAAGCTGGAG ATTGATGAAG AAACTTACCT AAGCTCATTC 
AAGCCTCACC TGATGGATGT GGTGTATACC TGGGCAACTG GGGCCACATT TGCCCATATC 
TGCAAAATGA CAGATGTTTT CGAAGGCAGT ATAATTCGTT GTATGAGGCG TCTGGAAGAA 
CTGCTTCGAC AGATGTGTCA AGCAGCAAAA GCCATTGGAA ACACAGAGCT GGAGAACAAA 
TTTGCTGAAG GAATTACCAA AATCAAGAGG GATATTGTAT TTGCTGCCAG CCTCTACTTA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss of the RNA helicase SKIV2L2 impairs mitotic progression and replication-dependent histone mRNA turnover in murine cell lines.
RNA (New York, N.Y.)23(6)910-926(2017 06)
Onderak AM,Anderson JT

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.
Cell169(3)523-537.e15(2017 Apr)
Lim J,Giri PK,Kazadi D,Laffleur B,Zhang W,Grinstein V,Pefanis E,Brown LM,Ladewig E,Martin O,Chen Y,Rabadan R,Boyer F,Rothschild G,Cogn? M,Pinaud E,Deng H,Basu U

Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.
Nature immunology17(12)1373-1380(2016 Dec)
Xing J,Weng L,Yuan B,Wang Z,Jia L,Jin R,Lu H,Li XC,Liu YJ,Zhang Z

Certain adenylated non-coding RNAs, including 5' leader sequences of primary microRNA transcripts, accumulate in mouse cells following depletion of the RNA helicase MTR4.
PloS one9(6)e99430(2014)
Dorweiler JE,Ni T,Zhu J,Munroe SH,Anderson JT

Localization of a novel RNA-binding protein, SKIV2L2, to the nucleus in the round spermatids of mice.
The Journal of reproduction and development57(4)457-67(2011 Sep)
Osman BA,Kawashima A,Tamba M,Satoh E,Kato Y,Iki A,Konishi K,Matsuda M,Okamura N

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Mtrex cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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