Ercc8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ercc8
Entrez Gene ID	71991
Full Name	excision repaiross-complementing rodent repair deficiency, complementation group 8
Synonyms	2410022P04Rik,2810431L23Rik,4631412O06Rik,B130065P18Rik,Ckn1,Csa
General protein information	Preferred Names excision repaiross-complementing rodent repair deficiency, complementation group 8 Names DNA excision repair protein ERCC-8 Cockayne syndrome 1 homolog cockayne syndrome WD repeat protein CSA homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 D2.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_028042.3	NP_082318.2	DNA excision repair protein ERCC-8
NM_001362403.1	NP_001349332.1	DNA excision repair protein ERCC-8 isoform 2
NM_028042.4	NP_082318.2	DNA excision repair protein ERCC-8 isoform 1
XM_017315608.1	XP_017171097.1	DNA excision repair protein ERCC-8 isoform X1
XM_011244697.2	XP_011242999.1	DNA excision repair protein ERCC-8 isoform X2
XM_006517763.3	XP_006517826.1	DNA excision repair protein ERCC-8 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ERCC8	NP_000073.1
Arabidopsis thaliana (thale cress)	AT1G19750	NP_173405.2
Xenopus tropicalis (tropical clawed frog)	ercc8	NP_001017179.1
Pan troglodytes (chimpanzee)	ERCC8	XP_003310766.1
Bos taurus (cattle)	ERCC8	NP_001103651.1
Oryza sativa (rice)	Os01g0857900	NP_001044857.2
Rattus norvegicus (Norway rat)	Ercc8	NP_001101120.2
Arabidopsis thaliana (thale cress)	ATCSA-1	NP_001031098.1
Canis lupus familiaris (dog)	ERCC8	XP_544353.1
Mus musculus (house mouse)	Ercc8	NP_082318.2
Gallus gallus (chicken)	ERCC8	XP_424742.1
Danio rerio (zebrafish)	ercc8	NP_001005984.1
Schizosaccharomyces pombe (fission yeast)	ckn1	NP_595307.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice.
Rainey RN, Ng SY, Llamas J, van der Horst GT, Segil N
The Journal of neuroscience : the official journal of the Society for Neuroscience36(17)4758-70(2016 04)

Cockayne syndrome group B (Csb) and group a (Csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.
Nagtegaal AP, Rainey RN, van der Pluijm I, Brandt RM, van der Horst GT, Borst JG, Segil N
The Journal of neuroscience : the official journal of the Society for Neuroscience35(10)4280-6(2015 Mar)

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.
Jaarsma D, van der Pluijm I, de Waard MC, Haasdijk ED, Brandt R, Vermeij M, Rijksen Y, Maas A, van Steeg H, Hoeijmakers JH, van der Horst GT
PLoS genetics7(12)e1002405(2011 Dec)

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging.
Kamenisch Y, Fousteri M, Knoch J, von Thaler AK, Fehrenbacher B, Kato H, Becker T, Doll? ME, Kuiper R, Majora M, Schaller M, van der Horst GT, van Steeg H, R?cken M, Rapaport D, Krutmann J, Mullenders LH, Berneburg M
The Journal of experimental medicine207(2)379-90(2010 Feb)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonistrated that Cockayne syndrome group A deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.
Title: Cockayne syndrome group B (Csb) and group a (Csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.

MtDNA mutations are highly increased in cells from subcutaneous fat of aged Csa(-/-) mice
Title: Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging.

difference in oxidative DNA damage sensitivity between CSA- and CSB-deficient cell lines and mice
Title: Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage.

The following Ercc8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ercc8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu49121	NM_001362403.1 Latest version!	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu49121	XM_006517763.3 Latest version!	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu05014	NM_028042.4 Latest version!	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu70812	XM_011244697.2 Latest version!	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu78524	XM_017315608.1 Latest version!	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu05014	NM_028042.3	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ercc8 ( NM_001362403.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001349332.1 Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu49121
Clone ID Related Accession (Same CDS sequence)	NM_001362403.1 , XM_006517763.3
Accession Version	NM_001362403.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	DNA excision repair protein ERCC-8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK014517.1 and BC056463.1. On Apr 14, 2018 this sequence version replaced XM_006517763.3. ##Evidence-Data-START## Transcript exon combination :: AK157504.1, AK014517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCACAT CCAGCTCATT TGATAAAACT CTGAAAGTGT GGGATACAAA CACATTGCAG 
GCTGCAGATG TGTTTAATTT TGAGGAAACA GTTTACAGTC ATCACATGTC CCCAGCAGCC 
ACCAAGCACT GTCTGGTAGC AGTTGGAACA AGAGGACCCA AGGTACAACT TTGTGACTTA 
AAGTCTGGAT CCTGTTCTCA CATTCTACAG GGTCACAGAC AGGAAATCTT GGCAGTTTCC 
TGGTCACCAC GCCATGACTA TATCTTGGCA ACAGCAAGTG CTGACAGTAG AGTAAAATTA 
TGGGATGTGA GAAGAGCGTC AGGATGCTTG CTTACTCTTG ACCAGCATAA TGGGAAAAAG 
TCACAAGCTG CTGAATCAGC AAACACTGCT CACAATGGGA AAGTTAACGG CTTATGTTTT 
ACAAGTGACG GCCTTCACCT GCTCACCATT GGCACAGACA ACCGAATGCG CCTCTGGAAT 
AGCTCCAGCG GGGACAACAC CCTGGTGAAC TATGGGAAGG TGTGTAATGA CAGCAGGAAA 
GGGCTGCAGT TCGCTGTCTC CTGTGGCTGC AGCTCAGAGT TTGTGTTTGT TCCCCACGGC 
AGCACCATCG CTGTGTACGC AGTCCACTCG GGAGAGCGGC TCGCCATGCT CAAGGGACAT 
TACAAAAGCG TCGACTGCTG TGTGTTCCAG CCTAATTTCC AGGAACTTTA CAGTGGAAGC 
AGGGACTGCA ATATTCTTGC TTGGGTACCA CCTTCCTATG AGCCAGTTCC TGATGATGAC 
GATGAAGCTC CAGCCAAATC CCAGTTAAAC CCAGCATTCG CGGACGCCTG GAGCAGCAGT 
GACGAGGATG GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001349332.1
CDS	294..1148
Translation	MFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRHDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAAESANTAHNGKVNGLCFTSDGLHLLTIGTDNRMRLWNSSSGDNTLVNYGKVCNDSRKGLQFAVSCGCSSEFVFVPHGSTIAVYAVHSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPPSYEPVPDDDDEAPAKSQLNPAFADAWSSSDEDG

Target ORF information:

RefSeq Version	NM_001362403.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001362403.1

ORF Insert Sequence:

ATGTTCACAT CCAGCTCATT TGATAAAACT CTGAAAGTGT GGGATACAAA CACATTGCAG 
GCTGCAGATG TGTTTAATTT TGAGGAAACA GTTTACAGTC ATCACATGTC CCCAGCAGCC 
ACCAAGCACT GTCTGGTAGC AGTTGGAACA AGAGGACCCA AGGTACAACT TTGTGACTTA 
AAGTCTGGAT CCTGTTCTCA CATTCTACAG GGTCACAGAC AGGAAATCTT GGCAGTTTCC 
TGGTCACCAC GCCATGACTA TATCTTGGCA ACAGCAAGTG CTGACAGTAG AGTAAAATTA 
TGGGATGTGA GAAGAGCGTC AGGATGCTTG CTTACTCTTG ACCAGCATAA TGGGAAAAAG 
TCACAAGCTG CTGAATCAGC AAACACTGCT CACAATGGGA AAGTTAACGG CTTATGTTTT 
ACAAGTGACG GCCTTCACCT GCTCACCATT GGCACAGACA ACCGAATGCG CCTCTGGAAT 
AGCTCCAGCG GGGACAACAC CCTGGTGAAC TATGGGAAGG TGTGTAATGA CAGCAGGAAA 
GGGCTGCAGT TCGCTGTCTC CTGTGGCTGC AGCTCAGAGT TTGTGTTTGT TCCCCACGGC 
AGCACCATCG CTGTGTACGC AGTCCACTCG GGAGAGCGGC TCGCCATGCT CAAGGGACAT 
TACAAAAGCG TCGACTGCTG TGTGTTCCAG CCTAATTTCC AGGAACTTTA CAGTGGAAGC 
AGGGACTGCA ATATTCTTGC TTGGGTACCA CCTTCCTATG AGCCAGTTCC TGATGATGAC 
GATGAAGCTC CAGCCAAATC CCAGTTAAAC CCAGCATTCG CGGACGCCTG GAGCAGCAGT 
GACGAGGATG GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ercc8 ( XM_006517763.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517826.1 Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu49121
Clone ID Related Accession (Same CDS sequence)	NM_001362403.1 , XM_006517763.3
Accession Version	XM_006517763.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	DNA excision repair protein ERCC-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517763.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCACAT CCAGCTCATT TGATAAAACT CTGAAAGTGT GGGATACAAA CACATTGCAG 
GCTGCAGATG TGTTTAATTT TGAGGAAACA GTTTACAGTC ATCACATGTC CCCAGCAGCC 
ACCAAGCACT GTCTGGTAGC AGTTGGAACA AGAGGACCCA AGGTACAACT TTGTGACTTA 
AAGTCTGGAT CCTGTTCTCA CATTCTACAG GGTCACAGAC AGGAAATCTT GGCAGTTTCC 
TGGTCACCAC GCCATGACTA TATCTTGGCA ACAGCAAGTG CTGACAGTAG AGTAAAATTA 
TGGGATGTGA GAAGAGCGTC AGGATGCTTG CTTACTCTTG ACCAGCATAA TGGGAAAAAG 
TCACAAGCTG CTGAATCAGC AAACACTGCT CACAATGGGA AAGTTAACGG CTTATGTTTT 
ACAAGTGACG GCCTTCACCT GCTCACCATT GGCACAGACA ACCGAATGCG CCTCTGGAAT 
AGCTCCAGCG GGGACAACAC CCTGGTGAAC TATGGGAAGG TGTGTAATGA CAGCAGGAAA 
GGGCTGCAGT TCGCTGTCTC CTGTGGCTGC AGCTCAGAGT TTGTGTTTGT TCCCCACGGC 
AGCACCATCG CTGTGTACGC AGTCCACTCG GGAGAGCGGC TCGCCATGCT CAAGGGACAT 
TACAAAAGCG TCGACTGCTG TGTGTTCCAG CCTAATTTCC AGGAACTTTA CAGTGGAAGC 
AGGGACTGCA ATATTCTTGC TTGGGTACCA CCTTCCTATG AGCCAGTTCC TGATGATGAC 
GATGAAGCTC CAGCCAAATC CCAGTTAAAC CCAGCATTCG CGGACGCCTG GAGCAGCAGT 
GACGAGGATG GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517826.1
CDS	297..1151
Translation	MFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRHDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAAESANTAHNGKVNGLCFTSDGLHLLTIGTDNRMRLWNSSSGDNTLVNYGKVCNDSRKGLQFAVSCGCSSEFVFVPHGSTIAVYAVHSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPPSYEPVPDDDDEAPAKSQLNPAFADAWSSSDEDG

Target ORF information:

RefSeq Version	XM_006517763.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517763.3

ORF Insert Sequence:

ATGTTCACAT CCAGCTCATT TGATAAAACT CTGAAAGTGT GGGATACAAA CACATTGCAG 
GCTGCAGATG TGTTTAATTT TGAGGAAACA GTTTACAGTC ATCACATGTC CCCAGCAGCC 
ACCAAGCACT GTCTGGTAGC AGTTGGAACA AGAGGACCCA AGGTACAACT TTGTGACTTA 
AAGTCTGGAT CCTGTTCTCA CATTCTACAG GGTCACAGAC AGGAAATCTT GGCAGTTTCC 
TGGTCACCAC GCCATGACTA TATCTTGGCA ACAGCAAGTG CTGACAGTAG AGTAAAATTA 
TGGGATGTGA GAAGAGCGTC AGGATGCTTG CTTACTCTTG ACCAGCATAA TGGGAAAAAG 
TCACAAGCTG CTGAATCAGC AAACACTGCT CACAATGGGA AAGTTAACGG CTTATGTTTT 
ACAAGTGACG GCCTTCACCT GCTCACCATT GGCACAGACA ACCGAATGCG CCTCTGGAAT 
AGCTCCAGCG GGGACAACAC CCTGGTGAAC TATGGGAAGG TGTGTAATGA CAGCAGGAAA 
GGGCTGCAGT TCGCTGTCTC CTGTGGCTGC AGCTCAGAGT TTGTGTTTGT TCCCCACGGC 
AGCACCATCG CTGTGTACGC AGTCCACTCG GGAGAGCGGC TCGCCATGCT CAAGGGACAT 
TACAAAAGCG TCGACTGCTG TGTGTTCCAG CCTAATTTCC AGGAACTTTA CAGTGGAAGC 
AGGGACTGCA ATATTCTTGC TTGGGTACCA CCTTCCTATG AGCCAGTTCC TGATGATGAC 
GATGAAGCTC CAGCCAAATC CCAGTTAAAC CCAGCATTCG CGGACGCCTG GAGCAGCAGT 
GACGAGGATG GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ercc8 ( NM_028042.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082318.2 Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), mRNA.

Price & Availability↑

CloneID	OMu05014
Clone ID Related Accession (Same CDS sequence)	NM_028042.3 , NM_028042.4
Accession Version	NM_028042.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-29
Organism	Mus musculus(house mouse)
Product	DNA excision repair protein ERCC-8
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK157175.1. On Apr 5, 2007 this sequence version replaced NM_028042.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK157175.1, AK010576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGTGC TGACAGTAGA GTAAAATTAT GGGATGTGAG AAGAGCGTCA 
GGATGCTTGC TTACTCTTGA CCAGCATAAT GGGAAAAAGT CACAAGCTGC TGAATCAGCA 
AACACTGCTC ACAATGGGAA AGTTAACGGC TTATGTTTTA CAAGTGACGG CCTTCACCTG 
CTCACCATTG GCACAGACAA CCGAATGCGC CTCTGGAATA GCTCCAGCGG GGACAACACC 
CTGGTGAACT ATGGGAAGGT GTGTAATGAC AGCAGGAAAG GGCTGCAGTT CGCTGTCTCC 
TGTGGCTGCA GCTCAGAGTT TGTGTTTGTT CCCCACGGCA GCACCATCGC TGTGTACGCA 
GTCCACTCGG GAGAGCGGCT CGCCATGCTC AAGGGACATT ACAAAAGCGT CGACTGCTGT 
GTGTTCCAGC CTAATTTCCA GGAACTTTAC AGTGGAAGCA GGGACTGCAA TATTCTTGCT 
TGGGTACCAC CTTCCTATGA GCCAGTTCCT GATGATGACG ATGAAGCTCC AGCCAAATCC 
CAGTTAAACC CAGCATTCGC GGACGCCTGG AGCAGCAGTG ACGAGGATGG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082318.2
CDS	57..1250
Translation	MLSFLSARQSGLEDPLRLRRAQSTRRVLGLELNKDRDVERIHGSGVNTLDIEPVEGRYMLSGGSDGVVVLYDLENASRQPHYTCKAVCSVGRSHPDVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRHDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAAESANTAHNGKVNGLCFTSDGLHLLTIGTDNRMRLWNSSSGDNTLVNYGKVCNDSRKGLQFAVSCGCSSEFVFVPHGSTIAVYAVHSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPPSYEPVPDDDDEAPAKSQLNPAFADAWSSSDEDG

Target ORF information:

RefSeq Version	NM_028042.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028042.3

ORF Insert Sequence:

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGTGC TGACAGTAGA GTAAAATTAT GGGATGTGAG AAGAGCGTCA 
GGATGCTTGC TTACTCTTGA CCAGCATAAT GGGAAAAAGT CACAAGCTGC TGAATCAGCA 
AACACTGCTC ACAATGGGAA AGTTAACGGC TTATGTTTTA CAAGTGACGG CCTTCACCTG 
CTCACCATTG GCACAGACAA CCGAATGCGC CTCTGGAATA GCTCCAGCGG GGACAACACC 
CTGGTGAACT ATGGGAAGGT GTGTAATGAC AGCAGGAAAG GGCTGCAGTT CGCTGTCTCC 
TGTGGCTGCA GCTCAGAGTT TGTGTTTGTT CCCCACGGCA GCACCATCGC TGTGTACGCA 
GTCCACTCGG GAGAGCGGCT CGCCATGCTC AAGGGACATT ACAAAAGCGT CGACTGCTGT 
GTGTTCCAGC CTAATTTCCA GGAACTTTAC AGTGGAAGCA GGGACTGCAA TATTCTTGCT 
TGGGTACCAC CTTCCTATGA GCCAGTTCCT GATGATGACG ATGAAGCTCC AGCCAAATCC 
CAGTTAAACC CAGCATTCGC GGACGCCTGG AGCAGCAGTG ACGAGGATGG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ercc8 ( NM_028042.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082318.2 Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05014
Clone ID Related Accession (Same CDS sequence)	NM_028042.3 , NM_028042.4
Accession Version	NM_028042.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	DNA excision repair protein ERCC-8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK010576.1 and BC056463.1. On Apr 14, 2018 this sequence version replaced NM_028042.3. ##Evidence-Data-START## Transcript exon combination :: AK157175.1, AK010576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGTGC TGACAGTAGA GTAAAATTAT GGGATGTGAG AAGAGCGTCA 
GGATGCTTGC TTACTCTTGA CCAGCATAAT GGGAAAAAGT CACAAGCTGC TGAATCAGCA 
AACACTGCTC ACAATGGGAA AGTTAACGGC TTATGTTTTA CAAGTGACGG CCTTCACCTG 
CTCACCATTG GCACAGACAA CCGAATGCGC CTCTGGAATA GCTCCAGCGG GGACAACACC 
CTGGTGAACT ATGGGAAGGT GTGTAATGAC AGCAGGAAAG GGCTGCAGTT CGCTGTCTCC 
TGTGGCTGCA GCTCAGAGTT TGTGTTTGTT CCCCACGGCA GCACCATCGC TGTGTACGCA 
GTCCACTCGG GAGAGCGGCT CGCCATGCTC AAGGGACATT ACAAAAGCGT CGACTGCTGT 
GTGTTCCAGC CTAATTTCCA GGAACTTTAC AGTGGAAGCA GGGACTGCAA TATTCTTGCT 
TGGGTACCAC CTTCCTATGA GCCAGTTCCT GATGATGACG ATGAAGCTCC AGCCAAATCC 
CAGTTAAACC CAGCATTCGC GGACGCCTGG AGCAGCAGTG ACGAGGATGG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082318.2
CDS	57..1250
Translation	MLSFLSARQSGLEDPLRLRRAQSTRRVLGLELNKDRDVERIHGSGVNTLDIEPVEGRYMLSGGSDGVVVLYDLENASRQPHYTCKAVCSVGRSHPDVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRHDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAAESANTAHNGKVNGLCFTSDGLHLLTIGTDNRMRLWNSSSGDNTLVNYGKVCNDSRKGLQFAVSCGCSSEFVFVPHGSTIAVYAVHSGERLAMLKGHYKSVDCCVFQPNFQELYSGSRDCNILAWVPPSYEPVPDDDDEAPAKSQLNPAFADAWSSSDEDG

Target ORF information:

RefSeq Version	NM_028042.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028042.4

ORF Insert Sequence:

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGTGC TGACAGTAGA GTAAAATTAT GGGATGTGAG AAGAGCGTCA 
GGATGCTTGC TTACTCTTGA CCAGCATAAT GGGAAAAAGT CACAAGCTGC TGAATCAGCA 
AACACTGCTC ACAATGGGAA AGTTAACGGC TTATGTTTTA CAAGTGACGG CCTTCACCTG 
CTCACCATTG GCACAGACAA CCGAATGCGC CTCTGGAATA GCTCCAGCGG GGACAACACC 
CTGGTGAACT ATGGGAAGGT GTGTAATGAC AGCAGGAAAG GGCTGCAGTT CGCTGTCTCC 
TGTGGCTGCA GCTCAGAGTT TGTGTTTGTT CCCCACGGCA GCACCATCGC TGTGTACGCA 
GTCCACTCGG GAGAGCGGCT CGCCATGCTC AAGGGACATT ACAAAAGCGT CGACTGCTGT 
GTGTTCCAGC CTAATTTCCA GGAACTTTAC AGTGGAAGCA GGGACTGCAA TATTCTTGCT 
TGGGTACCAC CTTCCTATGA GCCAGTTCCT GATGATGACG ATGAAGCTCC AGCCAAATCC 
CAGTTAAACC CAGCATTCGC GGACGCCTGG AGCAGCAGTG ACGAGGATGG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ercc8 ( XM_011244697.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242999.1 Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X4, mRNA.

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CloneID	OMu70812
Clone ID Related Accession (Same CDS sequence)	XM_011244697.2
Accession Version	XM_011244697.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 705bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	DNA excision repair protein ERCC-8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011244697.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGGTG CACATGTATG AGTGTAAGCC AGCGGCTGAC ACTGGGGTTG 
TCGTCCTCCA CTGGATTTAT TCAGAAGCTC TCCACTGAGC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011242999.1
CDS	83..787
Translation	MLSFLSARQSGLEDPLRLRRAQSTRRVLGLELNKDRDVERIHGSGVNTLDIEPVEGRYMLSGGSDGVVVLYDLENASRQPHYTCKAVCSVGRSHPDVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRHDYILATARCTCMSVSQRLTLGLSSSTGFIQKLSTEP

Target ORF information:

RefSeq Version	XM_011244697.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011244697.2

ORF Insert Sequence:

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGGTG CACATGTATG AGTGTAAGCC AGCGGCTGAC ACTGGGGTTG 
TCGTCCTCCA CTGGATTTAT TCAGAAGCTC TCCACTGAGC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ercc8 ( XM_017315608.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017171097.1 Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OMu78524
Clone ID Related Accession (Same CDS sequence)	XM_017315608.1
Accession Version	XM_017315608.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	DNA excision repair protein ERCC-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGGTG CACATGTATG AGTAGGTGCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017171097.1
CDS	83..727
Translation	MLSFLSARQSGLEDPLRLRRAQSTRRVLGLELNKDRDVERIHGSGVNTLDIEPVEGRYMLSGGSDGVVVLYDLENASRQPHYTCKAVCSVGRSHPDVHKYSVETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRHDYILATARCTCMSRCI

Target ORF information:

RefSeq Version	XM_017315608.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017315608.1

ORF Insert Sequence:

ATGTTGAGCT TTTTGTCCGC TCGACAGTCG GGTTTGGAGG ACCCTCTTCG CTTGCGTAGA 
GCGCAGTCCA CACGGAGGGT CCTGGGGCTG GAGTTAAACA AAGACAGGGA TGTGGAAAGA 
ATCCATGGCA GTGGGGTTAA CACCCTCGAC ATTGAGCCCG TTGAAGGAAG ATACATGTTG 
TCAGGTGGCT CCGATGGCGT GGTTGTACTC TATGACCTTG AGAACGCCAG CAGACAGCCC 
CATTACACAT GTAAAGCAGT GTGTTCCGTT GGCAGAAGCC ATCCCGATGT TCACAAATAC 
AGCGTGGAGA CTGTTCAGTG GTATCCTCAT GACACTGGCA TGTTCACATC CAGCTCATTT 
GATAAAACTC TGAAAGTGTG GGATACAAAC ACATTGCAGG CTGCAGATGT GTTTAATTTT 
GAGGAAACAG TTTACAGTCA TCACATGTCC CCAGCAGCCA CCAAGCACTG TCTGGTAGCA 
GTTGGAACAA GAGGACCCAA GGTACAACTT TGTGACTTAA AGTCTGGATC CTGTTCTCAC 
ATTCTACAGG GTCACAGACA GGAAATCTTG GCAGTTTCCT GGTCACCACG CCATGACTAT 
ATCTTGGCAA CAGCAAGGTG CACATGTATG AGTAGGTGCA TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience36(17)4758-70(2016 04)
Rainey RN,Ng SY,Llamas J,van der Horst GT,Segil N

Cockayne syndrome group B (Csb) and group a (Csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(10)4280-6(2015 Mar)
Nagtegaal AP,Rainey RN,van der Pluijm I,Brandt RM,van der Horst GT,Borst JG,Segil N

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.
PLoS genetics7(12)e1002405(2011 Dec)
Jaarsma D,van der Pluijm I,de Waard MC,Haasdijk ED,Brandt R,Vermeij M,Rijksen Y,Maas A,van Steeg H,Hoeijmakers JH,van der Horst GT

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging.
The Journal of experimental medicine207(2)379-90(2010 Feb)
Kamenisch Y,Fousteri M,Knoch J,von Thaler AK,Fehrenbacher B,Kato H,Becker T,Doll? ME,Kuiper R,Majora M,Schaller M,van der Horst GT,van Steeg H,R?cken M,Rapaport D,Krutmann J,Mullenders LH,Berneburg M

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

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Ercc8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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