Nkiras2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nkiras2
Entrez Gene ID	71966
Full Name	NFKB inhibitor interacting Ras-like protein 2
Synonyms	2410003M04Rik,4930527H08Rik,D630018G21Rik,KBRAS2
General protein information	Preferred Names NFKB inhibitor interacting Ras-like protein 2 Names NF-kappa-B inhibitor-interacting Ras-like protein 2 I-kappa-B-interacting Ras-like protein 2 kappa B-Ras protein 2 kappaB-Ras2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 D

mRNA and Protein(s)

mRNA	Protein	Name
XM_017314776.1	XP_017170265.1	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1
XM_030246341.1	XP_030102201.1	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1
NM_028024.2	NP_082300.1	NF-kappa-B inhibitor-interacting Ras-like protein 2
XM_017314775.1	XP_017170264.1	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nkiras2	NP_001099309.1
Gallus gallus (chicken)	NKIRAS2	NP_001006333.1
Danio rerio (zebrafish)	nkiras2	NP_001003433.1
Xenopus tropicalis (tropical clawed frog)	nkiras2	XP_002939079.1
Homo sapiens (human)	NKIRAS2	NP_001138399.1
Canis lupus familiaris (dog)	NKIRAS2	XP_537638.1
Mus musculus (house mouse)	Nkiras2	NP_082300.1
Pan troglodytes (chimpanzee)	NKIRAS2	XP_003953066.1
	NKIRAS2	XP_001093984.2
Bos taurus (cattle)	NKIRAS2	NP_001068855.1
Danio rerio (zebrafish)	LOC100538046	XP_003198129.1

Gene Ontology
Bibliography

Related articles in PubMed

?B-Ras proteins regulate both NF-?B-dependent inflammation and Ral-dependent proliferation.
Oeckinghaus A, Postler TS, Rao P, Schmitt H, Schmitt V, Grinberg-Bleyer Y, K?hn LI, Gruber CW, Lienhard GE, Ghosh S
Cell reports8(6)1793-1807(2014 Sep)

KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.
Tago K, Funakoshi-Tago M, Sakinawa M, Mizuno N, Itoh H
The Journal of biological chemistry285(40)30622-33(2010 Oct)

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ
PLoS genetics5(6)e1000511(2009 Jun)

RelA/p65 regulation of IkappaBbeta.
Hertlein E, Wang J, Ladner KJ, Bakkar N, Guttridge DC
Molecular and cellular biology25(12)4956-68(2005 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

KappaB-Ras2 is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.
Title: KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.

The following Nkiras2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nkiras2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04975	NM_028024.2 Latest version!	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu04975	XM_017314776.1 Latest version!	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu04975	XM_030246341.1 Latest version!	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu04975	XM_017314775.1 Latest version!	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nkiras2 ( NM_028024.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082300.1 Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), mRNA.

Price & Availability↑

CloneID	OMu04975
Clone ID Related Accession (Same CDS sequence)	XM_017314776.1 , XM_030246341.1 , NM_028024.2 , XM_017314775.1
Accession Version	NM_028024.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	NF-kappa-B inhibitor-interacting Ras-like protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL591469.9. On Nov 17, 2006 this sequence version replaced NM_028024.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK010371.1, AK083475.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082300.1
CDS	69..644
Translation	MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGAELPKHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFIYLASKMTQPQSKSAFPLSRKNKGSGSLDG

Target ORF information:

RefSeq Version	NM_028024.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028024.2

ORF Insert Sequence:

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nkiras2 ( XM_017314776.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170265.1 Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu04975
Clone ID Related Accession (Same CDS sequence)	XM_017314776.1 , XM_030246341.1 , NM_028024.2 , XM_017314775.1
Accession Version	XM_017314776.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170265.1
CDS	396..971
Translation	MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGAELPKHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFIYLASKMTQPQSKSAFPLSRKNKGSGSLDG

Target ORF information:

RefSeq Version	XM_017314776.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017314776.1

ORF Insert Sequence:

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nkiras2 ( XM_030246341.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030102201.1 Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04975
Clone ID Related Accession (Same CDS sequence)	XM_017314776.1 , XM_030246341.1 , NM_028024.2 , XM_017314775.1
Accession Version	XM_030246341.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030102201.1
CDS	1176..1751
Translation	MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGAELPKHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFIYLASKMTQPQSKSAFPLSRKNKGSGSLDG

Target ORF information:

RefSeq Version	XM_030246341.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246341.1

ORF Insert Sequence:

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nkiras2 ( XM_017314775.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170264.1 Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04975
Clone ID Related Accession (Same CDS sequence)	XM_017314776.1 , XM_030246341.1 , NM_028024.2 , XM_017314775.1
Accession Version	XM_017314775.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170264.1
CDS	402..977
Translation	MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGAELPKHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFIYLASKMTQPQSKSAFPLSRKNKGSGSLDG

Target ORF information:

RefSeq Version	XM_017314775.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017314775.1

ORF Insert Sequence:

ATGGGGAAGA GCTGCAAGGT GGTCGTGTGC GGCCAGGCAT CTGTGGGCAA AACTTCAATC 
CTTGAGCAGC TTCTGTACGG GAACCATGTC GTGGGTTCTG AGATGATCGA GACCCAGGAG 
GACATCTATG TAGGCTCCAT CGAGACAGAC CGAGGGGTGC GGGAGCAGGT GCGTTTCTAT 
GATACACGGG GTCTCCGGGA TGGGGCCGAG CTGCCCAAGC ACTGCTTCTC CTGCACCGAT 
GGCTACGTCC TGGTCTACAG CACAGACAGC CGAGAGTCGT TCCAGCGCGT CGAGCTGCTC 
AAGAAGGAGA TCGACAAGTC CAAGGACAAG AAGGAGGTCA CCATCGTGGT CCTTGGCAAC 
AAGTGTGACC TGCAGGAGCA GCGTCGCGTA GACCCTGACG TGGCCCAGCA CTGGGCCAAG 
TCCGAGAAGG TGAAGCTATG GGAGGTGTCG GTGGCTGACC GACGCTCCCT CCTAGAGCCT 
TTCATCTACC TGGCCAGCAA GATGACCCAG CCGCAGAGCA AGTCTGCCTT CCCCCTCAGC 
CGCAAGAACA AGGGCAGCGG CTCCTTGGAT GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

?B-Ras proteins regulate both NF-?B-dependent inflammation and Ral-dependent proliferation.
Cell reports8(6)1793-1807(2014 Sep)
Oeckinghaus A,Postler TS,Rao P,Schmitt H,Schmitt V,Grinberg-Bleyer Y,K?hn LI,Gruber CW,Lienhard GE,Ghosh S

KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.
The Journal of biological chemistry285(40)30622-33(2010 Oct)
Tago K,Funakoshi-Tago M,Sakinawa M,Mizuno N,Itoh H

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
PLoS genetics5(6)e1000511(2009 Jun)
Sansom SN,Griffiths DS,Faedo A,Kleinjan DJ,Ruan Y,Smith J,van Heyningen V,Rubenstein JL,Livesey FJ

RelA/p65 regulation of IkappaBbeta.
Molecular and cellular biology25(12)4956-68(2005 Jun)
Hertlein E,Wang J,Ladner KJ,Bakkar N,Guttridge DC

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Nkiras2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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