Coq2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Coq2
Entrez Gene ID	71883
Full Name	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Synonyms	2310002F18Rik,PHB:PPT
General protein information	Preferred Names coenzyme Q2 4-hydroxybenzoate polyprenyltransferase Names 4-hydroxybenzoate polyprenyltransferase, mitochondrial 4-HB polyprenyltransferase PHB:polyprenyltransferase coenzyme Q2 homolog, prenyltransferase para-hydroxybenzoate--polyprenyltransferase, mitochondrial
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 E4

mRNA and Protein(s)

mRNA	Protein	Name
NM_027978.2	NP_082254.2	4-hydroxybenzoate polyprenyltransferase, mitochondrial precursor

Pathways from BioSystems

Homologies

	LOC707681	XP_002808454.1
Rattus norvegicus (Norway rat)	Coq2	NP_001037720.1
Gallus gallus (chicken)	COQ2	XP_420564.3
Danio rerio (zebrafish)	coq2	NP_001082955.1
Drosophila melanogaster (fruit fly)	Coq2	NP_649789.1
Saccharomyces cerevisiae (baker's yeast)	COQ2	NP_014439.3
Eremothecium gossypii	AGOS_AGL231W	NP_986436.1
Schizosaccharomyces pombe (fission yeast)	ppt1	NP_593219.2
Neurospora crassa	NCU01553	XP_956256.1
Pan troglodytes (chimpanzee)	COQ2	XP_526592.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004513	XP_003436832.1
Caenorhabditis elegans (roundworm)	coq-2	NP_871684.1
Arabidopsis thaliana (thale cress)	PPT1	NP_001190815.1
Homo sapiens (human)	COQ2	NP_056512.5
Bos taurus (cattle)	COQ2	NP_001039358.1
Mus musculus (house mouse)	Coq2	NP_082254.2
Kluyveromyces lactis	KLLA0F10307g	XP_455549.1
Canis lupus familiaris (dog)	COQ2	XP_535634.2
Magnaporthe oryzae (rice blast fungus)	MGG_01067	XP_003717872.1
Oryza sativa (rice)	Os08g0322600	NP_001061539.1
Xenopus tropicalis (tropical clawed frog)	LOC100486844	XP_002936501.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues.
Parrado-Fern?ndez C, L?pez-Lluch G, Rodr?guez-Bies E, Santa-Cruz S, Navas P, Ramsey JJ, Villalba JM
Free radical biology & medicine50(12)1728-36(2011 Jun)

Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice.
O'Leary J, Osborne LR
PloS one6(8)e23868(2011)

Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.
Tkatchenko TV, Moreno-Rodriguez RA, Conway SJ, Molkentin JD, Markwald RR, Tkatchenko AV
Physiological genomics39(3)160-8(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues
Title: Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues.

The following Coq2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Coq2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu13033	NM_027978.2 Latest version!	Mus musculus coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (Coq2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Coq2 ( NM_027978.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082254.2 Mus musculus coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (Coq2), mRNA.

Price & Availability↑

CloneID	OMu13033
Clone ID Related Accession (Same CDS sequence)	NM_027978.2
Accession Version	NM_027978.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	4-hydroxybenzoate polyprenyltransferase, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK009092.1 and CK626929.1. On Feb 6, 2008 this sequence version replaced NM_027978.1. ##Evidence-Data-START## Transcript exon combination :: AK009092.1, BC080773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGCTGCGCT GGGGAGGCGC GGGGCTCGCG CGGGGCCTGC GGGCCGTTCG GTCCGCATGG 
CTGCGAGGTC CGCGCGGGCT CCCATTGGCC CTGGTGCGCA GCGCAGGGGT TCCGGGCGCG 
CGGGATCGGC GAGCCCCGGC CCCCGGGACG CAGCGGGGCC GAGCTCTCAG CCTGTCGGCC 
GCGGCCGTGG TGAACTCGGC GCCCCGCCCG CTGCAGCCCT ACCTGCGCCT CATGCGCCTG 
GACAAGCCCA TAGGAACCTG GCTGCTGTAT TTGCCATGCA CTTGGAGCAT TGGTCTGGCC 
GCTGACCCAG GTTGTTTTCC AGACTGGTAC ATGTTATCAC TTTTTGGCAC TGGAGCTATT 
CTGATGCGTG GAGCAGGCTG TACTATTAAT GACATGTGGG ACCGTGACTT CGATAAAAAG 
GTTACAAGGA CAGCAAACCG CCCAATCGCT GCTGGAGACA TTTCGACCTT CCAGTCCTTC 
GTCTTCCTTG GGGGACAGCT GACCTTGGCA CTGGGCGTTC TCCTGTGTTT AAACTACTAC 
AGTATAGCAA TGGGAGCAGC GTCCTTACTT CTTGTCGTCA CCTACCCACT AGTGAAAAGA 
ATCACGTTTT GGCCTCAGTT GGCTTTGGGA TTGACTTTTA ATTGGGGTGC GTTACTCGGA 
TGGTCTGCTG TCAAGGGCTC CTGTGATCCG GCTGTATGCC TGCCTCTGTA TTTTTCTGGA 
GTTATGTGGA CACTGATATA TGATACTATC TATGCCCACC AGGACAAGAA AGACGATGCT 
CTGATCGGCC TGAAGTCCAC AGCACTGCTG TTCCAGGAGA ACACAAGGCA GTGGCTTAGT 
GGCTTTGGGG TCGCCATGGT GGCAGCGCTG AGCCTGGCGG GAGCCAACAA TGGTCAGACT 
GTCCCCTACT ACGCTGCTGT GGCTGCGGTG GGAGCCCACC TGGCTCACCA GATTTACACT 
GTAGACATCC ACAGAGCCGA GGACTGCTGG GACAAGTTCA CCTCCAACCG CACAGTAGGA 
ATGCTCCTGT TCTTAGGGAT TGTCCTTGGA AACCTGTGCA AAGAAAAGAC GGAAGAAGCA 
AAAGATGCTG AAGCTGTTAG AGTGGGAAGT GAGCAGACGA GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082254.2
CDS	16..1140
Translation	MLRWGGAGLARGLRAVRSAWLRGPRGLPLALVRSAGVPGARDRRAPAPGTQRGRALSLSAAAVVNSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAADPGCFPDWYMLSLFGTGAILMRGAGCTINDMWDRDFDKKVTRTANRPIAAGDISTFQSFVFLGGQLTLALGVLLCLNYYSIAMGAASLLLVVTYPLVKRITFWPQLALGLTFNWGALLGWSAVKGSCDPAVCLPLYFSGVMWTLIYDTIYAHQDKKDDALIGLKSTALLFQENTRQWLSGFGVAMVAALSLAGANNGQTVPYYAAVAAVGAHLAHQIYTVDIHRAEDCWDKFTSNRTVGMLLFLGIVLGNLCKEKTEEAKDAEAVRVGSEQTS

Target ORF information:

RefSeq Version	NM_027978.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (Coq2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027978.2

ORF Insert Sequence:

ATGCTGCGCT GGGGAGGCGC GGGGCTCGCG CGGGGCCTGC GGGCCGTTCG GTCCGCATGG 
CTGCGAGGTC CGCGCGGGCT CCCATTGGCC CTGGTGCGCA GCGCAGGGGT TCCGGGCGCG 
CGGGATCGGC GAGCCCCGGC CCCCGGGACG CAGCGGGGCC GAGCTCTCAG CCTGTCGGCC 
GCGGCCGTGG TGAACTCGGC GCCCCGCCCG CTGCAGCCCT ACCTGCGCCT CATGCGCCTG 
GACAAGCCCA TAGGAACCTG GCTGCTGTAT TTGCCATGCA CTTGGAGCAT TGGTCTGGCC 
GCTGACCCAG GTTGTTTTCC AGACTGGTAC ATGTTATCAC TTTTTGGCAC TGGAGCTATT 
CTGATGCGTG GAGCAGGCTG TACTATTAAT GACATGTGGG ACCGTGACTT CGATAAAAAG 
GTTACAAGGA CAGCAAACCG CCCAATCGCT GCTGGAGACA TTTCGACCTT CCAGTCCTTC 
GTCTTCCTTG GGGGACAGCT GACCTTGGCA CTGGGCGTTC TCCTGTGTTT AAACTACTAC 
AGTATAGCAA TGGGAGCAGC GTCCTTACTT CTTGTCGTCA CCTACCCACT AGTGAAAAGA 
ATCACGTTTT GGCCTCAGTT GGCTTTGGGA TTGACTTTTA ATTGGGGTGC GTTACTCGGA 
TGGTCTGCTG TCAAGGGCTC CTGTGATCCG GCTGTATGCC TGCCTCTGTA TTTTTCTGGA 
GTTATGTGGA CACTGATATA TGATACTATC TATGCCCACC AGGACAAGAA AGACGATGCT 
CTGATCGGCC TGAAGTCCAC AGCACTGCTG TTCCAGGAGA ACACAAGGCA GTGGCTTAGT 
GGCTTTGGGG TCGCCATGGT GGCAGCGCTG AGCCTGGCGG GAGCCAACAA TGGTCAGACT 
GTCCCCTACT ACGCTGCTGT GGCTGCGGTG GGAGCCCACC TGGCTCACCA GATTTACACT 
GTAGACATCC ACAGAGCCGA GGACTGCTGG GACAAGTTCA CCTCCAACCG CACAGTAGGA 
ATGCTCCTGT TCTTAGGGAT TGTCCTTGGA AACCTGTGCA AAGAAAAGAC GGAAGAAGCA 
AAAGATGCTG AAGCTGTTAG AGTGGGAAGT GAGCAGACGA GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues.
Free radical biology & medicine50(12)1728-36(2011 Jun)
Parrado-Fern?ndez C,L?pez-Lluch G,Rodr?guez-Bies E,Santa-Cruz S,Navas P,Ramsey JJ,Villalba JM

Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice.
PloS one6(8)e23868(2011)
O'Leary J,Osborne LR

Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.
Physiological genomics39(3)160-8(2009 Nov)
Tkatchenko TV,Moreno-Rodriguez RA,Conway SJ,Molkentin JD,Markwald RR,Tkatchenko AV

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Coq2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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