Myo1e cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Myo1e
Entrez Gene ID	71602
Full Name	myosin IE
Synonyms	2310020N23Rik,9130023P14Rik,AA407778,myosin-1e,myr 3
General protein information	Preferred Names myosin IE Names unconventional myosin-Ie molecular motor unconventional myosin 1E
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 D\|9 39.41 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011242814.1	XP_011241116.1	unconventional myosin-Ie isoform X1
NM_181072.3	NP_851417.2	unconventional myosin-Ie

Pathways from BioSystems

Homologies

Homo sapiens (human)	MYO1E	NP_004989.2
Pan troglodytes (chimpanzee)	MYO1E	XP_510448.2
	MYO1E	XP_002804857.1
Bos taurus (cattle)	MYO1E	XP_002690899.2
Mus musculus (house mouse)	Myo1e	NP_851417.2
Gallus gallus (chicken)	MYO1E	XP_413782.4
Caenorhabditis elegans (roundworm)	hum-1	NP_492393.1
Canis lupus familiaris (dog)	MYO1E	XP_535500.3
Rattus norvegicus (Norway rat)	Myo1e	NP_775124.1
Danio rerio (zebrafish)	myo1ea	XP_005168984.1
Xenopus tropicalis (tropical clawed frog)	myo1e.2	NP_001011082.1

Gene Ontology
Bibliography

Related articles in PubMed

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.
Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, B?ttcher RT, Lee JH, Ordog T, Meves A
Proceedings of the National Academy of Sciences of the United States of America114(15)3933-3938(2017 Apr)

Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.
Ouderkirk-Pecone JL, Goreczny GJ, Chase SE, Tatum AH, Turner CE, Krendel M
Oncotarget7(29)46419-46432(2016 Jul)

Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate.
Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P
BMC biology1419(2016 Mar)

Crucial role for the LSP1-myosin1e bimolecular complex in the regulation of Fc? receptor-driven phagocytosis.
Maxeiner S, Shi N, Schalla C, Aydin G, Hoss M, Vogel S, Zenke M, Sechi AS
Molecular biology of the cell26(9)1652-64(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the LSP1-myosin1e bimolecular complex plays a pivotal role in the regulation of actin cytoskeleton remodeling during Fc gamma receptor-driven phagocytosis.
Title: Crucial role for the LSP1-myosin1e bimolecular complex in the regulation of Fc? receptor-driven phagocytosis.

Myo1e regulates TLR4-triggered macrophage spreading, chemokine release, and antigen presentation via MHC class II.
Title: Class I myosin Myo1e regulates TLR4-triggered macrophage spreading, chemokine release, and antigen presentation via MHC class II.

Overexpression of Myo1e can enhance podocyte migration ability, endocytosis, and attachment to the glomerular basement membrane
Title: Overexpression of Myo1e in mouse podocytes enhances cellular endocytosis, migration, and adhesion.

These findings suggest that myo1e represents a component of the slit diaphragm complex and may contribute to regulating junctional integrity in kidney podocytes.
Title: Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes.

Myo1e is a key component contributing to the functional integrity of podocytes.
Title: Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes.

The following Myo1e gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myo1e cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07935	NM_181072.3 Latest version!	Mus musculus myosin IE (Myo1e), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$650.30 $929.00
OMu70719	XM_011242814.1 Latest version!	Mus musculus myosin IE (Myo1e), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Myo1e ( NM_181072.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_851417.2 Mus musculus myosin IE (Myo1e), mRNA.

Price & Availability↑

CloneID	OMu07935
Clone ID Related Accession (Same CDS sequence)	NM_181072.3
Accession Version	NM_181072.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3324bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	unconventional myosin-Ie
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK029145.1, CX242330.1, BB220783.2, BY761514.1, BG086565.2, BG076620.2, AA250515.1, AK018649.1 and CAAA01204697.1. On or before Mar 2, 2012 this sequence version replaced XM_003689436.1, NM_181072.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC051391.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAGCA AAGGCGCCTA CCGGTACCAT TGGCAGAGCC ACAATGTCAA GCACAGTGGT 
GTGGACGACA TGGTTCTACT GTCCAAGATC ACAGAGAGCT CCATTGTAGA GAACCTGAAG 
AAGAGATACA TGGACGACTA TATTTTTACA TATATAGGGT CTGTATTAAT CTCTGTCAAC 
CCATTCAAGC AAATGCCATA TTTTGGAGAA AAAGAAGTCG AAATGTACCA AGGAGCGGCA 
CAGTATGAGA ACCCGCCTCA TATCTATGCC CTTGCTGATA GTATGTACAG AAACATGATC 
ATCGACAGAG AGAACCAGTG TGTCATCATC AGCGGTGAAA GTGGTGCTGG AAAGACAGTG 
GCTGCCAAGT ACATTATGAG CTATGTCTCC AGAGTGTCTG GAGGAGGCCC CAAGGTCCAG 
CATGTGAAGG ACATCATCCT TCAATCCAAC CCGCTCCTGG AGGCCTTCGG AAACGCCAAG 
ACAGTGCGCA ACAACAACTC CAGCCGATTT GGAAAATACT TTGAAATCCA GTTCAGTCCA 
GGTGGGGAAC CAGATGGTGG CAAGATCTCC AACTTCCTTC TGGAAAAGTC CAGAGTGGTG 
ATGCGGAACC CGGGGGAACG GAGCTTCCAC ATATTCTACC AGCTCATTGA GGGTGCCTCT 
CCAGAGCAGA AGCAAAGCCT TGGCATCACC AGCATGGACT ACTATTACTA CCTGAGCCTC 
TCGGGGTCCT ACAAGGTGGA TGACATTGAT GACAAGCGGG ATTTCCAGGA AACCCTGCAC 
GCCATGAATG TGATTGGAAT CTTCTCGGAA GAGCAGACTC TCGTGTTGCA GATTGTGGCT 
GGAATTCTCC ACTTGGGAAA CATCAGCTTC AAAGAAGTGG GCAACTATGC CGCCGTGGAG 
AGTGAAGAAT TTTTGGCTTT TCCTGCGTAT CTGCTGGGTA TAAACCAAGA CCGGTTAAAA 
GAGAAGCTAA CGAGCCGCCA GATGGACAGT AAGTGGGGAG GAAAGTCAGA GTCCATCCAT 
GTGACCCTCA ACGTGGAGCA GGCCTGCTAC ACCAGGGACG CGCTCGCCAA GGCCCTGCAC 
GCACGAGTCT TTGATTTCTT GGTAGATTCT ATCAATAAAG CCATGGAGAA GGACCACGAG 
GAGTACAACA TTGGAGTCCT GGACATCTAT GGCTTTGAAA TATTTCAGAA AAATGGCTTT 
GAGCAGTTCT GCATCAATTT CGTTAACGAA AAATTACAGC AGATTTTTAT TGAGCTGACG 
CTAAAAGCAG AGCAGGAAGA ATACGTTCAG GAGGGAATAA GATGGACACC CATTGAATAT 
TTCAATAATA AAATCGTGTG TGACCTCATA GAGAGCAAAG TCAACCCTCC TGGGATTATG 
AGCATCCTGG ATGACGTGTG CGCCACCATG CATGCTGTGG GTGAGGGGGC TGACCAGACT 
CTGCTACAGA AGCTCCAGAT GCAGATCGGG AGCCATGAGC ACTTCAACAG CTGGAACCAA 
GGCTTCATCA TTCACCACTA CGCTGGGAAG GTTTCCTATG ACATGGACGG CTTCTGCGAA 
AGGAACCGGG ATGTGCTTTT CATGGACCTG ATTGAACTCA TGCAGAGCAG TGAGCTGCCT 
TTTATAAAGT CTTTATTTCC TGAAAACCTG CAAGCTGACA AGAAAGGGCG CCCAACGACC 
GCAGGAAGCA AAATAAAGAA ACAAGCCAAC GACCTGGTGA GCACCCTGAT GAAATGCACA 
CCCCACTACA TTCGCTGCAT AAAACCAAAC GAAACCAAGA AGCCTAAAGA CTGGGAGGAG 
AGCAGAGTGA AGCATCAAGT GGAGTACCTG GGTCTCAAAG AAAACATCCG AGTGAGAAGA 
GCTGGTTATG CTTATCGGCG TGTCTTCCAG AAGTTTCTAC AGAGGTATGC CATTCTGACC 
AAAGCTACCT GGCCTGTGTG GAGAGGAGAT GAGAAACAAG GTGTCCTCCA TCTACTGCAG 
TCTGTCAACA TGGACAGCGA CCAGTTCCAG CTTGGGAGAA GTAAAGTGTT CATCAAAGCC 
CCAGAGTCTC TGTTTCTTCT AGAAGAGATG AGAGAGAGAA AGTACGATGG TTACGCACGT 
GTGATACAGA AAACATGGAG GAAGTTCGTG GCCCGCAAGA AATATGTTCA AATGAGAGAA 
GAAGCCTCAG ACCTGCTGTT GAACAAGAAG GAGAGGAGGA GAAACAGCAT CAACCGAAAC 
TTCATCGGGG ACTACATCGG GATGGAGGAG CGCCCGGAAC TGCAGCAGTT TGTAGGCAAG 
AGGGAGAAGA TTGACTTTGC TGACACAGTC ACCAAGTACG ACAGGAGGTT CAAGGGTGTC 
AAGCGAGACC TGCTGCTAAC CCCCAAGTGC TTGTACTTAA TTGGAAGGGA GAAGGTGAAG 
CAAGGCCCAG ACAAAGGTGT TGTGAAGGAA GTCCTGAAGC GGAGGATCGA GGTGGAAAGG 
ATCCTGTCCG TGTCCCTCAG TACCATGCAG GATGACATCT TCATTCTCCA CGAGCAAGAA 
TATGACAGTT TGCTGGAGTC CGTCTTTAAA ACGGAGTTCC TGAGCCTCTT AGCAAAGCGA 
TACGAGGAAA AAACCCAGAA GCAACTACCT CTGAAATTCA GCAATACCCT TGAACTGAAG 
TTGAAAAAGG AGAACTGGGG TCCCTGGAGT GCAGGGGGCT CCCGGCAAGT GCAGTTCCAC 
CAAGGCTTCG GTGACCTGGC TATCCTCAAG CCCAGCAACA AAGTGCTGCA GGTCAGCATC 
GGACCCGGGC TGCCCAAGAA CTCCCGTCCT ACCAGAAGAA ACACCGTCAC CAGCAGAGGG 
TATCCAGGTG GAACTAAGAA CAATTACCCG ATGAGAGCTG CCCCTGCTCC CCCAGGATGC 
CATCAAAACG GAGTCATACG AAACCAGTTT GTGCCTCCTC CCCATGCCTT TGGAAACCAG 
AGGTCCAATC AGAAAAGCCT GTACACCTCT ATGGCCCGCC CACCCTTGCC AAGGCAACAG 
TCCACCGGCT CGGATCGATT GTCTCAGACG CCAGAGAGCC TGGATTTCCT CAAGGTCCCG 
GACCAGGGTG TTGCTGGAGT CCGAAGACAA ACGAGCAGCC GGCCTCCCCC AGCAGGGGGC 
AGACCAAAGC CTCAACCCAA GCCTAAGCCT CAGGTGCCAC AGTGCAAGGC CTTGTATGCC 
TATGATGCTC AGGACACGGA CGAACTCAGC TTCAACGCCA ACGATATTAT TGATATTATT 
AAAGAAGACC CTTCTGGCTG GTGGACGGGT AGACTACGAG GCAAGCAGGG CCTGTTTCCT 
AACAACTACG TCACCAAGAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_851417.2
CDS	352..3675
Translation	MGSKGAYRYHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEVEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEERPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGVVKEVLKRRIEVERILSVSLSTMQDDIFILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAILKPSNKVLQVSIGPGLPKNSRPTRRNTVTSRGYPGGTKNNYPMRAAPAPPGCHQNGVIRNQFVPPPHAFGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGVAGVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI

Target ORF information:

RefSeq Version	NM_181072.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus myosin IE (Myo1e), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181072.3

ORF Insert Sequence:

ATGGGCAGCA AAGGCGCCTA CCGGTACCAT TGGCAGAGCC ACAATGTCAA GCACAGTGGT 
GTGGACGACA TGGTTCTACT GTCCAAGATC ACAGAGAGCT CCATTGTAGA GAACCTGAAG 
AAGAGATACA TGGACGACTA TATTTTTACA TATATAGGGT CTGTATTAAT CTCTGTCAAC 
CCATTCAAGC AAATGCCATA TTTTGGAGAA AAAGAAGTCG AAATGTACCA AGGAGCGGCA 
CAGTATGAGA ACCCGCCTCA TATCTATGCC CTTGCTGATA GTATGTACAG AAACATGATC 
ATCGACAGAG AGAACCAGTG TGTCATCATC AGCGGTGAAA GTGGTGCTGG AAAGACAGTG 
GCTGCCAAGT ACATTATGAG CTATGTCTCC AGAGTGTCTG GAGGAGGCCC CAAGGTCCAG 
CATGTGAAGG ACATCATCCT TCAATCCAAC CCGCTCCTGG AGGCCTTCGG AAACGCCAAG 
ACAGTGCGCA ACAACAACTC CAGCCGATTT GGAAAATACT TTGAAATCCA GTTCAGTCCA 
GGTGGGGAAC CAGATGGTGG CAAGATCTCC AACTTCCTTC TGGAAAAGTC CAGAGTGGTG 
ATGCGGAACC CGGGGGAACG GAGCTTCCAC ATATTCTACC AGCTCATTGA GGGTGCCTCT 
CCAGAGCAGA AGCAAAGCCT TGGCATCACC AGCATGGACT ACTATTACTA CCTGAGCCTC 
TCGGGGTCCT ACAAGGTGGA TGACATTGAT GACAAGCGGG ATTTCCAGGA AACCCTGCAC 
GCCATGAATG TGATTGGAAT CTTCTCGGAA GAGCAGACTC TCGTGTTGCA GATTGTGGCT 
GGAATTCTCC ACTTGGGAAA CATCAGCTTC AAAGAAGTGG GCAACTATGC CGCCGTGGAG 
AGTGAAGAAT TTTTGGCTTT TCCTGCGTAT CTGCTGGGTA TAAACCAAGA CCGGTTAAAA 
GAGAAGCTAA CGAGCCGCCA GATGGACAGT AAGTGGGGAG GAAAGTCAGA GTCCATCCAT 
GTGACCCTCA ACGTGGAGCA GGCCTGCTAC ACCAGGGACG CGCTCGCCAA GGCCCTGCAC 
GCACGAGTCT TTGATTTCTT GGTAGATTCT ATCAATAAAG CCATGGAGAA GGACCACGAG 
GAGTACAACA TTGGAGTCCT GGACATCTAT GGCTTTGAAA TATTTCAGAA AAATGGCTTT 
GAGCAGTTCT GCATCAATTT CGTTAACGAA AAATTACAGC AGATTTTTAT TGAGCTGACG 
CTAAAAGCAG AGCAGGAAGA ATACGTTCAG GAGGGAATAA GATGGACACC CATTGAATAT 
TTCAATAATA AAATCGTGTG TGACCTCATA GAGAGCAAAG TCAACCCTCC TGGGATTATG 
AGCATCCTGG ATGACGTGTG CGCCACCATG CATGCTGTGG GTGAGGGGGC TGACCAGACT 
CTGCTACAGA AGCTCCAGAT GCAGATCGGG AGCCATGAGC ACTTCAACAG CTGGAACCAA 
GGCTTCATCA TTCACCACTA CGCTGGGAAG GTTTCCTATG ACATGGACGG CTTCTGCGAA 
AGGAACCGGG ATGTGCTTTT CATGGACCTG ATTGAACTCA TGCAGAGCAG TGAGCTGCCT 
TTTATAAAGT CTTTATTTCC TGAAAACCTG CAAGCTGACA AGAAAGGGCG CCCAACGACC 
GCAGGAAGCA AAATAAAGAA ACAAGCCAAC GACCTGGTGA GCACCCTGAT GAAATGCACA 
CCCCACTACA TTCGCTGCAT AAAACCAAAC GAAACCAAGA AGCCTAAAGA CTGGGAGGAG 
AGCAGAGTGA AGCATCAAGT GGAGTACCTG GGTCTCAAAG AAAACATCCG AGTGAGAAGA 
GCTGGTTATG CTTATCGGCG TGTCTTCCAG AAGTTTCTAC AGAGGTATGC CATTCTGACC 
AAAGCTACCT GGCCTGTGTG GAGAGGAGAT GAGAAACAAG GTGTCCTCCA TCTACTGCAG 
TCTGTCAACA TGGACAGCGA CCAGTTCCAG CTTGGGAGAA GTAAAGTGTT CATCAAAGCC 
CCAGAGTCTC TGTTTCTTCT AGAAGAGATG AGAGAGAGAA AGTACGATGG TTACGCACGT 
GTGATACAGA AAACATGGAG GAAGTTCGTG GCCCGCAAGA AATATGTTCA AATGAGAGAA 
GAAGCCTCAG ACCTGCTGTT GAACAAGAAG GAGAGGAGGA GAAACAGCAT CAACCGAAAC 
TTCATCGGGG ACTACATCGG GATGGAGGAG CGCCCGGAAC TGCAGCAGTT TGTAGGCAAG 
AGGGAGAAGA TTGACTTTGC TGACACAGTC ACCAAGTACG ACAGGAGGTT CAAGGGTGTC 
AAGCGAGACC TGCTGCTAAC CCCCAAGTGC TTGTACTTAA TTGGAAGGGA GAAGGTGAAG 
CAAGGCCCAG ACAAAGGTGT TGTGAAGGAA GTCCTGAAGC GGAGGATCGA GGTGGAAAGG 
ATCCTGTCCG TGTCCCTCAG TACCATGCAG GATGACATCT TCATTCTCCA CGAGCAAGAA 
TATGACAGTT TGCTGGAGTC CGTCTTTAAA ACGGAGTTCC TGAGCCTCTT AGCAAAGCGA 
TACGAGGAAA AAACCCAGAA GCAACTACCT CTGAAATTCA GCAATACCCT TGAACTGAAG 
TTGAAAAAGG AGAACTGGGG TCCCTGGAGT GCAGGGGGCT CCCGGCAAGT GCAGTTCCAC 
CAAGGCTTCG GTGACCTGGC TATCCTCAAG CCCAGCAACA AAGTGCTGCA GGTCAGCATC 
GGACCCGGGC TGCCCAAGAA CTCCCGTCCT ACCAGAAGAA ACACCGTCAC CAGCAGAGGG 
TATCCAGGTG GAACTAAGAA CAATTACCCG ATGAGAGCTG CCCCTGCTCC CCCAGGATGC 
CATCAAAACG GAGTCATACG AAACCAGTTT GTGCCTCCTC CCCATGCCTT TGGAAACCAG 
AGGTCCAATC AGAAAAGCCT GTACACCTCT ATGGCCCGCC CACCCTTGCC AAGGCAACAG 
TCCACCGGCT CGGATCGATT GTCTCAGACG CCAGAGAGCC TGGATTTCCT CAAGGTCCCG 
GACCAGGGTG TTGCTGGAGT CCGAAGACAA ACGAGCAGCC GGCCTCCCCC AGCAGGGGGC 
AGACCAAAGC CTCAACCCAA GCCTAAGCCT CAGGTGCCAC AGTGCAAGGC CTTGTATGCC 
TATGATGCTC AGGACACGGA CGAACTCAGC TTCAACGCCA ACGATATTAT TGATATTATT 
AAAGAAGACC CTTCTGGCTG GTGGACGGGT AGACTACGAG GCAAGCAGGG CCTGTTTCCT 
AACAACTACG TCACCAAGAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Myo1e ( XM_011242814.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011241116.1 Mus musculus myosin IE (Myo1e), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70719
Clone ID Related Accession (Same CDS sequence)	XM_011242814.1
Accession Version	XM_011242814.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	unconventional myosin-Ie isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGACTT CAGAGCCACT TCCTCTTATG ACTAAACCCG GCAGCAAAGG CGCCTACCGG 
TACCATTGGC AGAGCCACAA TGTCAAGCAC AGTGGTGTGG ACGACATGGT TCTACTGTCC 
AAGATCACAG AGAGCTCCAT TGTAGAGAAC CTGAAGAAGA GATACATGGA CGACTATATT 
TTTACATATA TAGGGTCTGT ATTAATCTCT GTCAACCCAT TCAAGCAAAT GCCATATTTT 
GGAGAAAAAG AAGTCGAAAT GTACCAAGGA GCGGCACAGT ATGAGAACCC GCCTCATATC 
TATGCCCTTG CTGATAGTAT GTACAGAAAC ATGATCATCG ACAGAGAGAA CCAGTGTGTC 
ATCATCAGCG GTGAAAGTGG TGCTGGAAAG ACAGTGGCTG CCAAGTACAT TATGAGCTAT 
GTCTCCAGAG TGTCTGGAGG AGGCCCCAAG GTCCAGCATG TGAAGGACAT CATCCTTCAA 
TCCAACCCGC TCCTGGAGGC CTTCGGAAAC GCCAAGACAG TGCGCAACAA CAACTCCAGC 
CGATTTGGAA AATACTTTGA AATCCAGTTC AGTCCAGGTG GGGAACCAGA TGGTGGCAAG 
ATCTCCAACT TCCTTCTGGA AAAGTCCAGA GTGGTGATGC GGAACCCGGG GGAACGGAGC 
TTCCACATAT TCTACCAGCT CATTGAGGGT GCCTCTCCAG AGCAGAAGCA AAGCCTTGGC 
ATCACCAGCA TGGACTACTA TTACTACCTG AGCCTCTCGG GGTCCTACAA GGTGGATGAC 
ATTGATGACA AGCGGGATTT CCAGGAAACC CTGCACGCCA TGAATGTGAT TGGAATCTTC 
TCGGAAGAGC AGACTCTCGT GTTGCAGATT GTGGCTGGAA TTCTCCACTT GGGAAACATC 
AGCTTCAAAG AAGTGGGCAA CTATGCCGCC GTGGAGAGTG AAGAATTTTT GGCTTTTCCT 
GCGTATCTGC TGGGTATAAA CCAAGACCGG TTAAAAGAGA AGCTAACGAG CCGCCAGATG 
GACAGTAAGT GGGGAGGAAA GTCAGAGTCC ATCCATGTGA CCCTCAACGT GGAGCAGGCC 
TGCTACACCA GGGACGCGCT CGCCAAGGCC CTGCACGCAC GAGTCTTTGA TTTCTTGGTA 
GATTCTATCA ATAAAGCCAT GGAGAAGGAC CACGAGGAGT ACAACATTGG AGTCCTGGAC 
ATCTATGGCT TTGAAATATT TCAGAAAAAT GGCTTTGAGC AGTTCTGCAT CAATTTCGTT 
AACGAAAAAT TACAGCAGAT TTTTATTGAG CTGACGCTAA AAGCAGAGCA GGAAGAATAC 
GTTCAGGAGG GAATAAGATG GACACCCATT GAATATTTCA ATAATAAAAT CGTGTGTGAC 
CTCATAGAGA GCAAAGTCAA CCCTCCTGGG ATTATGAGCA TCCTGGATGA CGTGTGCGCC 
ACCATGCATG CTGTGGGTGA GGGGGCTGAC CAGACTCTGC TACAGAAGCT CCAGATGCAG 
ATCGGGAGCC ATGAGCACTT CAACAGCTGG AACCAAGGCT TCATCATTCA CCACTACGCT 
GGGAAGGTTT CCTATGACAT GGACGGCTTC TGCGAAAGGA ACCGGGATGT GCTTTTCATG 
GACCTGATTG AACTCATGCA GAGCAGTGAG CTGCCTTTTA TAAAGTCTTT ATTTCCTGAA 
AACCTGCAAG CTGACAAGAA AGGGCGCCCA ACGACCGCAG GAAGCAAAAT AAAGAAACAA 
GCCAACGACC TGGTGAGCAC CCTGATGAAA TGCACACCCC ACTACATTCG CTGCATAAAA 
CCAAACGAAA CCAAGAAGCC TAAAGACTGG GAGGAGAGCA GAGTGAAGCA TCAAGTGGAG 
TACCTGGGTC TCAAAGAAAA CATCCGAGTG AGAAGAGCTG GTTATGCTTA TCGGCGTGTC 
TTCCAGAAGT TTCTACAGAG GTATGCCATT CTGACCAAAG CTACCTGGCC TGTGTGGAGA 
GGAGATGAGA AACAAGGTGT CCTCCATCTA CTGCAGTCTG TCAACATGGA CAGCGACCAG 
TTCCAGCTTG GGAGAAGTAA AGTGTTCATC AAAGCCCCAG AGTCTCTGTT TCTTCTAGAA 
GAGATGAGAG AGAGAAAGTA CGATGGTTAC GCACGTGTGA TACAGAAAAC ATGGAGGAAG 
TTCGTGGCCC GCAAGAAATA TGTTCAAATG AGAGAAGAAG CCTCAGACCT GCTGTTGAAC 
AAGAAGGAGA GGAGGAGAAA CAGCATCAAC CGAAACTTCA TCGGGGACTA CATCGGGATG 
GAGGAGCGCC CGGAACTGCA GCAGTTTGTA GGCAAGAGGG AGAAGATTGA CTTTGCTGAC 
ACAGTCACCA AGTACGACAG GAGGTTCAAG GGTGTCAAGC GAGACCTGCT GCTAACCCCC 
AAGTGCTTGT ACTTAATTGG AAGGGAGAAG GTGAAGCAAG GCCCAGACAA AGGTGTTGTG 
AAGGAAGTCC TGAAGCGGAG GATCGAGGTG GAAAGGATCC TGTCCGTGTC CCTCAGTACC 
ATGCAGGATG ACATCTTCAT TCTCCACGAG CAAGAATATG ACAGTTTGCT GGAGTCCGTC 
TTTAAAACGG AGTTCCTGAG CCTCTTAGCA AAGCGATACG AGGAAAAAAC CCAGAAGCAA 
CTACCTCTGA AATTCAGCAA TACCCTTGAA CTGAAGTTGA AAAAGGAGAA CTGGGGTCCC 
TGGAGTGCAG GGGGCTCCCG GCAAGTGCAG TTCCACCAAG GCTTCGGTGA CCTGGCTATC 
CTCAAGCCCA GCAACAAAGT GCTGCAGGTC AGCATCGGAC CCGGGCTGCC CAAGAACTCC 
CGTCCTACCA GAAGAAACAC CGTCACCAGC AGAGGGTATC CAGGTGGAAC TAAGAACAAT 
TACCCGATGA GAGCTGCCCC TGCTCCCCCA GGATGCCATC AAAACGGAGT CATACGAAAC 
CAGTTTGTGC CTCCTCCCCA TGCCTTTGGA AACCAGAGGT CCAATCAGAA AAGCCTGTAC 
ACCTCTATGG CCCGCCCACC CTTGCCAAGG CAACAGTCCA CCGGCTCGGA TCGATTGTCT 
CAGACGCCAG AGAGCCTGGA TTTCCTCAAG GTCCCGGACC AGGGTGTTGC TGGAGTCCGA 
AGACAAACGA GCAGCCGGCC TCCCCCAGCA GGGGGCAGAC CAAAGCCTCA ACCCAAGCCT 
AAGCCTCAGG TGCCACAGTG CAAGGCCTTG TATGCCTATG ATGCTCAGGA CACGGACGAA 
CTCAGCTTCA ACGCCAACGA TATTATTGAT ATTATTAAAG AAGACCCTTC TGGCTGGTGG 
ACGGGTAGAC TACGAGGCAA GCAGGGCCTG TTTCCTAACA ACTACGTCAC CAAGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241116.1
CDS	16..3375
Translation	MGTSEPLPLMTKPGSKGAYRYHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEVEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEERPELQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGVVKEVLKRRIEVERILSVSLSTMQDDIFILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAILKPSNKVLQVSIGPGLPKNSRPTRRNTVTSRGYPGGTKNNYPMRAAPAPPGCHQNGVIRNQFVPPPHAFGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGVAGVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI

Target ORF information:

RefSeq Version	XM_011242814.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus myosin IE (Myo1e), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242814.1

ORF Insert Sequence:

ATGGGGACTT CAGAGCCACT TCCTCTTATG ACTAAACCCG GCAGCAAAGG CGCCTACCGG 
TACCATTGGC AGAGCCACAA TGTCAAGCAC AGTGGTGTGG ACGACATGGT TCTACTGTCC 
AAGATCACAG AGAGCTCCAT TGTAGAGAAC CTGAAGAAGA GATACATGGA CGACTATATT 
TTTACATATA TAGGGTCTGT ATTAATCTCT GTCAACCCAT TCAAGCAAAT GCCATATTTT 
GGAGAAAAAG AAGTCGAAAT GTACCAAGGA GCGGCACAGT ATGAGAACCC GCCTCATATC 
TATGCCCTTG CTGATAGTAT GTACAGAAAC ATGATCATCG ACAGAGAGAA CCAGTGTGTC 
ATCATCAGCG GTGAAAGTGG TGCTGGAAAG ACAGTGGCTG CCAAGTACAT TATGAGCTAT 
GTCTCCAGAG TGTCTGGAGG AGGCCCCAAG GTCCAGCATG TGAAGGACAT CATCCTTCAA 
TCCAACCCGC TCCTGGAGGC CTTCGGAAAC GCCAAGACAG TGCGCAACAA CAACTCCAGC 
CGATTTGGAA AATACTTTGA AATCCAGTTC AGTCCAGGTG GGGAACCAGA TGGTGGCAAG 
ATCTCCAACT TCCTTCTGGA AAAGTCCAGA GTGGTGATGC GGAACCCGGG GGAACGGAGC 
TTCCACATAT TCTACCAGCT CATTGAGGGT GCCTCTCCAG AGCAGAAGCA AAGCCTTGGC 
ATCACCAGCA TGGACTACTA TTACTACCTG AGCCTCTCGG GGTCCTACAA GGTGGATGAC 
ATTGATGACA AGCGGGATTT CCAGGAAACC CTGCACGCCA TGAATGTGAT TGGAATCTTC 
TCGGAAGAGC AGACTCTCGT GTTGCAGATT GTGGCTGGAA TTCTCCACTT GGGAAACATC 
AGCTTCAAAG AAGTGGGCAA CTATGCCGCC GTGGAGAGTG AAGAATTTTT GGCTTTTCCT 
GCGTATCTGC TGGGTATAAA CCAAGACCGG TTAAAAGAGA AGCTAACGAG CCGCCAGATG 
GACAGTAAGT GGGGAGGAAA GTCAGAGTCC ATCCATGTGA CCCTCAACGT GGAGCAGGCC 
TGCTACACCA GGGACGCGCT CGCCAAGGCC CTGCACGCAC GAGTCTTTGA TTTCTTGGTA 
GATTCTATCA ATAAAGCCAT GGAGAAGGAC CACGAGGAGT ACAACATTGG AGTCCTGGAC 
ATCTATGGCT TTGAAATATT TCAGAAAAAT GGCTTTGAGC AGTTCTGCAT CAATTTCGTT 
AACGAAAAAT TACAGCAGAT TTTTATTGAG CTGACGCTAA AAGCAGAGCA GGAAGAATAC 
GTTCAGGAGG GAATAAGATG GACACCCATT GAATATTTCA ATAATAAAAT CGTGTGTGAC 
CTCATAGAGA GCAAAGTCAA CCCTCCTGGG ATTATGAGCA TCCTGGATGA CGTGTGCGCC 
ACCATGCATG CTGTGGGTGA GGGGGCTGAC CAGACTCTGC TACAGAAGCT CCAGATGCAG 
ATCGGGAGCC ATGAGCACTT CAACAGCTGG AACCAAGGCT TCATCATTCA CCACTACGCT 
GGGAAGGTTT CCTATGACAT GGACGGCTTC TGCGAAAGGA ACCGGGATGT GCTTTTCATG 
GACCTGATTG AACTCATGCA GAGCAGTGAG CTGCCTTTTA TAAAGTCTTT ATTTCCTGAA 
AACCTGCAAG CTGACAAGAA AGGGCGCCCA ACGACCGCAG GAAGCAAAAT AAAGAAACAA 
GCCAACGACC TGGTGAGCAC CCTGATGAAA TGCACACCCC ACTACATTCG CTGCATAAAA 
CCAAACGAAA CCAAGAAGCC TAAAGACTGG GAGGAGAGCA GAGTGAAGCA TCAAGTGGAG 
TACCTGGGTC TCAAAGAAAA CATCCGAGTG AGAAGAGCTG GTTATGCTTA TCGGCGTGTC 
TTCCAGAAGT TTCTACAGAG GTATGCCATT CTGACCAAAG CTACCTGGCC TGTGTGGAGA 
GGAGATGAGA AACAAGGTGT CCTCCATCTA CTGCAGTCTG TCAACATGGA CAGCGACCAG 
TTCCAGCTTG GGAGAAGTAA AGTGTTCATC AAAGCCCCAG AGTCTCTGTT TCTTCTAGAA 
GAGATGAGAG AGAGAAAGTA CGATGGTTAC GCACGTGTGA TACAGAAAAC ATGGAGGAAG 
TTCGTGGCCC GCAAGAAATA TGTTCAAATG AGAGAAGAAG CCTCAGACCT GCTGTTGAAC 
AAGAAGGAGA GGAGGAGAAA CAGCATCAAC CGAAACTTCA TCGGGGACTA CATCGGGATG 
GAGGAGCGCC CGGAACTGCA GCAGTTTGTA GGCAAGAGGG AGAAGATTGA CTTTGCTGAC 
ACAGTCACCA AGTACGACAG GAGGTTCAAG GGTGTCAAGC GAGACCTGCT GCTAACCCCC 
AAGTGCTTGT ACTTAATTGG AAGGGAGAAG GTGAAGCAAG GCCCAGACAA AGGTGTTGTG 
AAGGAAGTCC TGAAGCGGAG GATCGAGGTG GAAAGGATCC TGTCCGTGTC CCTCAGTACC 
ATGCAGGATG ACATCTTCAT TCTCCACGAG CAAGAATATG ACAGTTTGCT GGAGTCCGTC 
TTTAAAACGG AGTTCCTGAG CCTCTTAGCA AAGCGATACG AGGAAAAAAC CCAGAAGCAA 
CTACCTCTGA AATTCAGCAA TACCCTTGAA CTGAAGTTGA AAAAGGAGAA CTGGGGTCCC 
TGGAGTGCAG GGGGCTCCCG GCAAGTGCAG TTCCACCAAG GCTTCGGTGA CCTGGCTATC 
CTCAAGCCCA GCAACAAAGT GCTGCAGGTC AGCATCGGAC CCGGGCTGCC CAAGAACTCC 
CGTCCTACCA GAAGAAACAC CGTCACCAGC AGAGGGTATC CAGGTGGAAC TAAGAACAAT 
TACCCGATGA GAGCTGCCCC TGCTCCCCCA GGATGCCATC AAAACGGAGT CATACGAAAC 
CAGTTTGTGC CTCCTCCCCA TGCCTTTGGA AACCAGAGGT CCAATCAGAA AAGCCTGTAC 
ACCTCTATGG CCCGCCCACC CTTGCCAAGG CAACAGTCCA CCGGCTCGGA TCGATTGTCT 
CAGACGCCAG AGAGCCTGGA TTTCCTCAAG GTCCCGGACC AGGGTGTTGC TGGAGTCCGA 
AGACAAACGA GCAGCCGGCC TCCCCCAGCA GGGGGCAGAC CAAAGCCTCA ACCCAAGCCT 
AAGCCTCAGG TGCCACAGTG CAAGGCCTTG TATGCCTATG ATGCTCAGGA CACGGACGAA 
CTCAGCTTCA ACGCCAACGA TATTATTGAT ATTATTAAAG AAGACCCTTC TGGCTGGTGG 
ACGGGTAGAC TACGAGGCAA GCAGGGCCTG TTTCCTAACA ACTACGTCAC CAAGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.
Proceedings of the National Academy of Sciences of the United States of America114(15)3933-3938(2017 Apr)
Heim JB,Squirewell EJ,Neu A,Zocher G,Sominidi-Damodaran S,Wyles SP,Nikolova E,Behrendt N,Saunte DM,Lock-Andersen J,Gaonkar KS,Yan H,Sarkaria JN,Krendel M,van Deursen J,Sprangers R,Stehle T,B?ttcher RT,Lee JH,Ordog T,Meves A

Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.
Oncotarget7(29)46419-46432(2016 Jul)
Ouderkirk-Pecone JL,Goreczny GJ,Chase SE,Tatum AH,Turner CE,Krendel M

Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate.
BMC biology1419(2016 Mar)
Li A,Ma S,Smith SM,Lee MK,Fischer A,Borok Z,Bellusci S,Li C,Minoo P

Crucial role for the LSP1-myosin1e bimolecular complex in the regulation of Fc? receptor-driven phagocytosis.
Molecular biology of the cell26(9)1652-64(2015 May)
Maxeiner S,Shi N,Schalla C,Aydin G,Hoss M,Vogel S,Zenke M,Sechi AS

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Myo1e cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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