Megf10 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Megf10
Entrez Gene ID	70417
Full Name	multiple EGF-like-domains 10
Synonyms	3000002B06Rik,Gm331
General protein information	Preferred Names multiple EGF-like-domains 10 Names multiple epidermal growth factor-like domains protein 10 multiple EGF-like domains protein 10
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001979.2	NP_001001979.1	multiple epidermal growth factor-like domains protein 10 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Megf10	NP_001001979.1
Danio rerio (zebrafish)	megf10	XP_001922524.2
Xenopus tropicalis (tropical clawed frog)	megf10	NP_001072726.1
Pan troglodytes (chimpanzee)	MEGF10	XP_517907.2
Bos taurus (cattle)	MEGF10	NP_001039916.2
	MEGF10	XP_001097941.1
Canis lupus familiaris (dog)	MEGF10	XP_005626533.1
Homo sapiens (human)	MEGF10	NP_115822.1
Rattus norvegicus (Norway rat)	Megf10	NP_001094127.1
Gallus gallus (chicken)	MEGF10	XP_424719.3

Gene Ontology
Bibliography

Related articles in PubMed

Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.
Saha M, Mitsuhashi S, Jones MD, Manko K, Reddy HM, Bruels CC, Cho KA, Pacak CA, Draper I, Kang PB
Human molecular genetics26(15)2984-3000(2017 Aug)

Expression of MEGF10 in cholinergic and glutamatergic neurons.
Fujita Y, Maeda T, Kamaishi K, Saito R, Chiba K, Shen X, Zou K, Komano H
Neuroscience letters65325-30(2017 Jul)

Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes.
Iram T, Ramirez-Ortiz Z, Byrne MH, Coleman UA, Kingery ND, Means TK, Frenkel D, El Khoury J
The Journal of neuroscience : the official journal of the Society for Neuroscience36(19)5185-92(2016 05)

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.
Chung WS, Clarke LE, Wang GX, Stafford BK, Sher A, Chakraborty C, Joung J, Foo LC, Thompson A, Chen C, Smith SJ, Barres BA
Nature504(7480)394-400(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Megf10 binds with high affinity to C1q, an eat-me signal for apoptotic cells. Cells expressing Megf10 with EMARDD mutations have impaired apoptotic cell clearance and impaired binding to C1q.
Title: Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes.

studies reveal a novel role for astrocytes in mediating synapse elimination in the developing and adult brain, identify MEGF10 and MERTK as critical proteins in the synapse remodelling underlying neural circuit refinement
Title: Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.

Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy.
Title: Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy.

These results indicated that both Jedi-1 and MEGF10 can mediate phagocytosis independently through the recruitment of Syk.
Title: Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk.

in mouse, two related transmembrane proteins, MEGF10 and MEGF11, have critical roles in the formation of mosaics by two retinal interneuron subtypes, starburst amacrine cells and horizontal cells
Title: MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.

The following Megf10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Megf10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18399	NM_001001979.2 Latest version!	Mus musculus multiple EGF-like-domains 10 (Megf10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Megf10 ( NM_001001979.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001001979.1 Mus musculus multiple EGF-like-domains 10 (Megf10), mRNA.

Price & Availability↑

CloneID	OMu18399
Clone ID Related Accession (Same CDS sequence)	NM_001001979.2
Accession Version	NM_001001979.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Mus musculus(house mouse)
Product	multiple epidermal growth factor-like domains protein 10 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK147238.1, BC075647.1 and AK013855.1. On Feb 18, 2010 this sequence version replaced NM_001001979.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147238.1, BC075647.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGATTT CTTCAAGTTC GTGCCTGGGC CTCATCTGCT CACTGCTCTG TCACTGGGTG 
GGGACAGCAT CCTCCCTGAA CCTGGAAGAC CCCAACGTAT GCAGCCACTG GGAAAGCTAC 
TCGGTGACTG TGCAGGAGTC GTATCCACAT CCCTTCGATC AGATCTACTA CACAAGCTGC 
ACCGACATCC TGAACTGGTT TAAATGCACA CGGCACAGAA TCAGCTACCG GACAGCCTAC 
CGCCACGGGG AGAAAACCAT GTATAGACGC AAATCCCAGT GTTGCCCAGG ATTTTATGAA 
AGCCGAGACA TGTGTGTCCC TCACTGTGCT GATAAATGTG TCCATGGTCG CTGCATTGCT 
CCAAACACCT GTCAGTGTGA GCCTGGCTGG GGTGGGACCA ACTGTAGCAG TGCTTGTGAT 
GGTGATCACT GGGGGCCTCA CTGCAGCAGC CGATGCCAGT GCAAAAACAG AGCTTTGTGT 
AACCCCATCA CCGGTGCTTG CCACTGCGCT GCGGGCTACC GGGGATGGCG CTGCGAGGAC 
CGTTGTGAAC AGGGCACGTA CGGTAACGAC TGTCACCAAA GATGCCAGTG TCAGAATGGA 
GCGACCTGTG ACCACATCAC TGGGGAATGC CGTTGTTCAC CTGGGTACAC TGGAGCCTTC 
TGTGAGGATC TTTGTCCTCC TGGCAAACAT GGTCCACATT GTGAGCAGAG GTGTCCCTGC 
CAAAATGGGG GTGTGTGCCA CCATGTCACT GGAGAGTGCT CTTGCCCTTC TGGTTGGATG 
GGCACAGTGT GTGGTCAGCC CTGCCCTGAG GGTCGCTTTG GAAAGAACTG TTCCCAAGAA 
TGCCAGTGTC ACAATGGAGG AACGTGTGAT GCTGCCACAG GCCAGTGTCA CTGCAGCCCA 
GGATACACAG GGGAACGGTG TCAGGACGAA TGTCCTGTTG GGAGCTATGG AGTTCGCTGT 
GCTGAGGCCT GCAGGTGTGT CAACGGAGGC AAGTGTTACC ACGTGAGTGG TACATGCCTG 
TGCGAAGCAG GCTTTTCGGG TGAACTTTGC GAGGCGCGCC TGTGTCCCGA GGGGCTTTAC 
GGCATCAAAT GTGACAAGCG GTGCCCCTGC CACCTGGACA ACACTCACAG CTGTCATCCC 
ATGTCTGGAG AGTGTGGCTG CAAGCCGGGT TGGTCGGGAC TGTACTGTAA TGAAACATGC 
TCCCCTGGAT TCTACGGGGA GGCTTGCCAA CAGATCTGCA GCTGCCAGAA CGGGGCGGAC 
TGCGACAGTG TGACTGGAAG GTGTGCCTGC GCTCCAGGAT TCAAAGGGAC TGACTGCTCT 
ACTCCGTGTC CTCTGGGACG CTACGGGATA AATTGTTCTT CTCGCTGTGG CTGTAAAAAT 
GATGCTGTCT GTTCTCCTGT GGATGGATCA TGTATCTGTA AGGCAGGCTG GCACGGGGTG 
GACTGTTCCA TCCGCTGCCC CAGTGGCACA TGGGGCTTTG GCTGTAACCT AACGTGTCAG 
TGCCTCAATG GCGGTGCCTG CAACACGCTG GATGGGACCT GCACCTGTGC GCCCGGATGG 
CGAGGCGCGA AGTGTGAATT TCCCTGCCAG GATGGCACTT ATGGGCTGAA CTGTGCCGAG 
CGCTGTGACT GCAGCCATGC AGATGGCTGT CACCCCACTA CAGGCCATTG CCGCTGCCTC 
CCTGGATGGT CAGGTGTGCA CTGTGACAGT GTGTGCGCTG AGGGACGCTG GGGTCCTAAC 
TGCTCGCTGC CCTGCTACTG TAAAAATGGG GCTTCGTGTT CTCCGGATGA TGGCATCTGT 
GAGTGTGCAC CCGGATTCCG AGGCACCACT TGCCAGAGAA TCTGCTCCCC CGGTTTTTAT 
GGACATCGCT GTAGCCAGAC CTGCCCGCAG TGTGTGCACA GCAGTGGGCC CTGCCACCAC 
ATCACGGGCC TGTGTGACTG CTTACCTGGC TTCACCGGTG CCCTGTGCAA TGAAGTGTGT 
CCCAGTGGCA GATTTGGGAA AAACTGTGCA GGCGTTTGTA CTTGCACCAA CAATGGCACC 
TGTAACCCCA TCGACAGATC CTGCCAGTGT TACCCAGGCT GGATTGGCAG TGACTGCTCC 
CAGCCCTGTC CACCTGCGCA CTGGGGTCCG AACTGCATCC ACACCTGCAA CTGCCACAAC 
GGAGCCTTTT GCAGCGCCTA TGATGGGGAA TGCAAATGCA CTCCTGGCTG GACGGGGCTC 
TACTGCACTC AGAGATGCCC TCTGGGCTTC TATGGTAAGG ACTGTGCACT GATATGCCAA 
TGTCAAAACG GAGCTGACTG CGACCATATC TCGGGGCAGT GTACCTGCCG CACGGGATTC 
ATGGGACGGC ACTGTGAACA GAAGTGCCCT GCGGGAACAT ACGGCTATGG CTGTCGCCAG 
ATCTGTGACT GTCTGAACAA CTCCACCTGT GACCACATCA CTGGCACGTG TTACTGTAGC 
CCAGGATGGA AAGGGGCACG ATGTGACCAA GCTGGGGTTA TCATCGTGGG CAATCTGAAC 
AGCTTAAGCC GGACCAGCAC CGCCCTTCCT GCCGATTCCT ATCAGATCGG GGCCATCGCG 
GGCATCGTGG TCCTCGTTCT TGTTGTGCTC TTCCTGCTGG CGCTGTTCAT CATCTACAGA 
CACAAGCAGA AGAGGAAGGA ATCAAGCATG CCGGCCGTGA CCTACACCCC CGCCATGAGG 
GTCATCAATG CAGACTATAC CATCGCAGAA ACCCTGCCTC ACAGCAATGG TGGAAATGCC 
AACAGCCACT ACTTTACCAA TCCCAGTTAT CACACACTTA GCCAGTGTGC CACATCCCCT 
CATGTGAACA ATAGGGACAG GATGACCATT GCAAAGTCAA AAAACAATCA GCTGTTTGTG 
AATCTTAAAA ATGTGAATCC AGGGAAGAGA GGGACATTGG TGGACTGCAC TGGGACATTG 
CCAGCTGACT GGAAGCAAGG AGGCTACCTC AATGAGCTTG GTGCTTTCGG GCTGGACAGA 
AGCTACATGG GAAAGTCCTT AAAAGATCTG GGGAAGAACT CTGAATATAA TTCAAGCACT 
TGCTCCTTAA GCAGCTCTGA AAACCCATAT GCCACCATTA AAGACCCGCC TGCACTCCTG 
CCTAAAAGCT CCGAGTGCGG CTACGTGGAG ATGAAGTCGC CGGCGCGGAG AGACTCCCCA 
TATGCAGAGA TCAACAACTC AACTCCAGCC AACAGGAATG TCTATGAAGT CGAACCTACA 
GTGAGCGTTG TGCAAGGAGT ATTCAGCAAC AGCGGTCACG TCACCCAAGA CCCATATGAC 
CTTCCAAAGA ACAGTCACAT CCCTTGCCAT TATGACCTGC TGCCAGTAAG GGACAGTTCA 
TCCTCCCCAA AGAGAGAGGA TGGTGGTGGC AGCAACAGCA CCAGCAGCAA CAGCACCAGC 
AGCAGCAGCA GCAGCAGTGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001979.1
CDS	659..4102
Translation	MAISSSSCLGLICSLLCHWVGTASSLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNWFKCTRHRISYRTAYRHGEKTMYRRKSQCCPGFYESRDMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCSSRCQCKNRALCNPITGACHCAAGYRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHITGECRCSPGYTGAFCEDLCPPGKHGPHCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGSYGVRCAEACRCVNGGKCYHVSGTCLCEAGFSGELCEARLCPEGLYGIKCDKRCPCHLDNTHSCHPMSGECGCKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGRCACAPGFKGTDCSTPCPLGRYGINCSSRCGCKNDAVCSPVDGSCICKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGAKCEFPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGVCTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPAGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALPADSYQIGAIAGIVVLVLVVLFLLALFIIYRHKQKRKESSMPAVTYTPAMRVINADYTIAETLPHSNGGNANSHYFTNPSYHTLSQCATSPHVNNRDRMTIAKSKNNQLFVNLKNVNPGKRGTLVDCTGTLPADWKQGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSTCSLSSSENPYATIKDPPALLPKSSECGYVEMKSPARRDSPYAEINNSTPANRNVYEVEPTVSVVQGVFSNSGHVTQDPYDLPKNSHIPCHYDLLPVRDSSSSPKREDGGGSNSTSSNSTSSSSSSSE

Target ORF information:

RefSeq Version	NM_001001979.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus multiple EGF-like-domains 10 (Megf10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001979.2

ORF Insert Sequence:

ATGGCGATTT CTTCAAGTTC GTGCCTGGGC CTCATCTGCT CACTGCTCTG TCACTGGGTG 
GGGACAGCAT CCTCCCTGAA CCTGGAAGAC CCCAACGTAT GCAGCCACTG GGAAAGCTAC 
TCGGTGACTG TGCAGGAGTC GTATCCACAT CCCTTCGATC AGATCTACTA CACAAGCTGC 
ACCGACATCC TGAACTGGTT TAAATGCACA CGGCACAGAA TCAGCTACCG GACAGCCTAC 
CGCCACGGGG AGAAAACCAT GTATAGACGC AAATCCCAGT GTTGCCCAGG ATTTTATGAA 
AGCCGAGACA TGTGTGTCCC TCACTGTGCT GATAAATGTG TCCATGGTCG CTGCATTGCT 
CCAAACACCT GTCAGTGTGA GCCTGGCTGG GGTGGGACCA ACTGTAGCAG TGCTTGTGAT 
GGTGATCACT GGGGGCCTCA CTGCAGCAGC CGATGCCAGT GCAAAAACAG AGCTTTGTGT 
AACCCCATCA CCGGTGCTTG CCACTGCGCT GCGGGCTACC GGGGATGGCG CTGCGAGGAC 
CGTTGTGAAC AGGGCACGTA CGGTAACGAC TGTCACCAAA GATGCCAGTG TCAGAATGGA 
GCGACCTGTG ACCACATCAC TGGGGAATGC CGTTGTTCAC CTGGGTACAC TGGAGCCTTC 
TGTGAGGATC TTTGTCCTCC TGGCAAACAT GGTCCACATT GTGAGCAGAG GTGTCCCTGC 
CAAAATGGGG GTGTGTGCCA CCATGTCACT GGAGAGTGCT CTTGCCCTTC TGGTTGGATG 
GGCACAGTGT GTGGTCAGCC CTGCCCTGAG GGTCGCTTTG GAAAGAACTG TTCCCAAGAA 
TGCCAGTGTC ACAATGGAGG AACGTGTGAT GCTGCCACAG GCCAGTGTCA CTGCAGCCCA 
GGATACACAG GGGAACGGTG TCAGGACGAA TGTCCTGTTG GGAGCTATGG AGTTCGCTGT 
GCTGAGGCCT GCAGGTGTGT CAACGGAGGC AAGTGTTACC ACGTGAGTGG TACATGCCTG 
TGCGAAGCAG GCTTTTCGGG TGAACTTTGC GAGGCGCGCC TGTGTCCCGA GGGGCTTTAC 
GGCATCAAAT GTGACAAGCG GTGCCCCTGC CACCTGGACA ACACTCACAG CTGTCATCCC 
ATGTCTGGAG AGTGTGGCTG CAAGCCGGGT TGGTCGGGAC TGTACTGTAA TGAAACATGC 
TCCCCTGGAT TCTACGGGGA GGCTTGCCAA CAGATCTGCA GCTGCCAGAA CGGGGCGGAC 
TGCGACAGTG TGACTGGAAG GTGTGCCTGC GCTCCAGGAT TCAAAGGGAC TGACTGCTCT 
ACTCCGTGTC CTCTGGGACG CTACGGGATA AATTGTTCTT CTCGCTGTGG CTGTAAAAAT 
GATGCTGTCT GTTCTCCTGT GGATGGATCA TGTATCTGTA AGGCAGGCTG GCACGGGGTG 
GACTGTTCCA TCCGCTGCCC CAGTGGCACA TGGGGCTTTG GCTGTAACCT AACGTGTCAG 
TGCCTCAATG GCGGTGCCTG CAACACGCTG GATGGGACCT GCACCTGTGC GCCCGGATGG 
CGAGGCGCGA AGTGTGAATT TCCCTGCCAG GATGGCACTT ATGGGCTGAA CTGTGCCGAG 
CGCTGTGACT GCAGCCATGC AGATGGCTGT CACCCCACTA CAGGCCATTG CCGCTGCCTC 
CCTGGATGGT CAGGTGTGCA CTGTGACAGT GTGTGCGCTG AGGGACGCTG GGGTCCTAAC 
TGCTCGCTGC CCTGCTACTG TAAAAATGGG GCTTCGTGTT CTCCGGATGA TGGCATCTGT 
GAGTGTGCAC CCGGATTCCG AGGCACCACT TGCCAGAGAA TCTGCTCCCC CGGTTTTTAT 
GGACATCGCT GTAGCCAGAC CTGCCCGCAG TGTGTGCACA GCAGTGGGCC CTGCCACCAC 
ATCACGGGCC TGTGTGACTG CTTACCTGGC TTCACCGGTG CCCTGTGCAA TGAAGTGTGT 
CCCAGTGGCA GATTTGGGAA AAACTGTGCA GGCGTTTGTA CTTGCACCAA CAATGGCACC 
TGTAACCCCA TCGACAGATC CTGCCAGTGT TACCCAGGCT GGATTGGCAG TGACTGCTCC 
CAGCCCTGTC CACCTGCGCA CTGGGGTCCG AACTGCATCC ACACCTGCAA CTGCCACAAC 
GGAGCCTTTT GCAGCGCCTA TGATGGGGAA TGCAAATGCA CTCCTGGCTG GACGGGGCTC 
TACTGCACTC AGAGATGCCC TCTGGGCTTC TATGGTAAGG ACTGTGCACT GATATGCCAA 
TGTCAAAACG GAGCTGACTG CGACCATATC TCGGGGCAGT GTACCTGCCG CACGGGATTC 
ATGGGACGGC ACTGTGAACA GAAGTGCCCT GCGGGAACAT ACGGCTATGG CTGTCGCCAG 
ATCTGTGACT GTCTGAACAA CTCCACCTGT GACCACATCA CTGGCACGTG TTACTGTAGC 
CCAGGATGGA AAGGGGCACG ATGTGACCAA GCTGGGGTTA TCATCGTGGG CAATCTGAAC 
AGCTTAAGCC GGACCAGCAC CGCCCTTCCT GCCGATTCCT ATCAGATCGG GGCCATCGCG 
GGCATCGTGG TCCTCGTTCT TGTTGTGCTC TTCCTGCTGG CGCTGTTCAT CATCTACAGA 
CACAAGCAGA AGAGGAAGGA ATCAAGCATG CCGGCCGTGA CCTACACCCC CGCCATGAGG 
GTCATCAATG CAGACTATAC CATCGCAGAA ACCCTGCCTC ACAGCAATGG TGGAAATGCC 
AACAGCCACT ACTTTACCAA TCCCAGTTAT CACACACTTA GCCAGTGTGC CACATCCCCT 
CATGTGAACA ATAGGGACAG GATGACCATT GCAAAGTCAA AAAACAATCA GCTGTTTGTG 
AATCTTAAAA ATGTGAATCC AGGGAAGAGA GGGACATTGG TGGACTGCAC TGGGACATTG 
CCAGCTGACT GGAAGCAAGG AGGCTACCTC AATGAGCTTG GTGCTTTCGG GCTGGACAGA 
AGCTACATGG GAAAGTCCTT AAAAGATCTG GGGAAGAACT CTGAATATAA TTCAAGCACT 
TGCTCCTTAA GCAGCTCTGA AAACCCATAT GCCACCATTA AAGACCCGCC TGCACTCCTG 
CCTAAAAGCT CCGAGTGCGG CTACGTGGAG ATGAAGTCGC CGGCGCGGAG AGACTCCCCA 
TATGCAGAGA TCAACAACTC AACTCCAGCC AACAGGAATG TCTATGAAGT CGAACCTACA 
GTGAGCGTTG TGCAAGGAGT ATTCAGCAAC AGCGGTCACG TCACCCAAGA CCCATATGAC 
CTTCCAAAGA ACAGTCACAT CCCTTGCCAT TATGACCTGC TGCCAGTAAG GGACAGTTCA 
TCCTCCCCAA AGAGAGAGGA TGGTGGTGGC AGCAACAGCA CCAGCAGCAA CAGCACCAGC 
AGCAGCAGCA GCAGCAGTGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.
Human molecular genetics26(15)2984-3000(2017 Aug)
Saha M,Mitsuhashi S,Jones MD,Manko K,Reddy HM,Bruels CC,Cho KA,Pacak CA,Draper I,Kang PB

Expression of MEGF10 in cholinergic and glutamatergic neurons.
Neuroscience letters65325-30(2017 Jul)
Fujita Y,Maeda T,Kamaishi K,Saito R,Chiba K,Shen X,Zou K,Komano H

Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience36(19)5185-92(2016 05)
Iram T,Ramirez-Ortiz Z,Byrne MH,Coleman UA,Kingery ND,Means TK,Frenkel D,El Khoury J

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.
Nature504(7480)394-400(2013 Dec)
Chung WS,Clarke LE,Wang GX,Stafford BK,Sher A,Chakraborty C,Joung J,Foo LC,Thompson A,Chen C,Smith SJ,Barres BA

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Megf10 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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