H1f7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	H1f7
Entrez Gene ID	70069
Full Name	H1 histone family, member N, testis-specific
Synonyms	1700026P10Rik,H1.7,H1t2,Hanp1,mH1t2
General protein information	Preferred Names H1 histone family, member N, testis-specific Names testis-specific H1 histone expressed in haploid spermatids during spermiogenesis, specifically at the apical pole of round and elongating spermatids haploid germ cell-specific nuclear protein 1 histone H1t2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 F1
Summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. This gene encodes a testis specific protein that is required for spermatogenesis and male fertility. [provided by RefSeq, Oct 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_027304.2	NP_081580.2	testis-specific H1 histone

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Role of H1 linker histones in mammalian development and stem cell differentiation.
Pan C, Fan Y
Biochimica et biophysica acta1859(3)496-509(2016 Mar)

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice.
Tang MC, Jacobs SA, Mattiske DM, Soh YM, Graham AN, Tran A, Lim SL, Hudson DF, Kalitsis P, O'Bryan MK, Wong LH, Mann JR
PLoS genetics11(2)e1004964(2015 Feb)

Histone variants: key players of chromatin.
Biterge B, Schneider R
Cell and tissue research356(3)457-66(2014 Jun)

A unified phylogeny-based nomenclature for histone variants.
Talbert PB, Ahmad K, Almouzni G, Ausi? J, Berger F, Bhalla PL, Bonner WM, Cande WZ, Chadwick BP, Chan SW, Cross GA, Cui L, Dimitrov SI, Doenecke D, Eirin-L?pez JM, Gorovsky MA, Hake SB, Hamkalo BA, Holec S, Jacobsen SE, Kamieniarz K, Khochbin S, Ladurner AG, Landsman D, Latham JA, Loppin B, Malik HS, Marzluff WF, Pehrson JR, Postberg J, Schneider R, Singh MB, Smith MM, Thompson E, Torres-Padilla ME, Tremethick DJ, Turner BM, Waterborg JH, Wollmann H, Yelagandula R, Zhu B, Henikoff S
Epigenetics & chromatin57(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

H1T2 can be a useful molecular marker revealing chromatin disorganization in spermatids.
Title: Changes in intranuclear chromatin architecture induce bipolar nuclear localization of histone variant H1T2 in male haploid spermatids.

HANP1/H1T2 is essential for nuclear formation in functional spermatozoa and is specifically involved in the replacement of histones with protamines during spermiogenesis
Title: HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility.

The following H1f7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H1f7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58591	NM_027304.2 Latest version!	Mus musculus H1.7 linker histone (H1f7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

H1f7 ( NM_027304.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081580.2 Mus musculus H1.7 linker histone (H1f7), mRNA.

Price & Availability↑

CloneID	OMu58591
Clone ID Related Accession (Same CDS sequence)	NM_027304.2
Accession Version	NM_027304.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Mus musculus(house mouse)
Product	testis-specific H1 histone
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC105982.10, BC052363.1 and AB016273.1. On Sep 3, 2009 this sequence version replaced NM_027304.1. ##RefSeq-Attributes-START## replication-independent histone :: PMID: 24781148 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAGG CTGTCCAGCC CAGTGGGGAA TCCCAAGGCG CAGAACTTAC GATCCAGATC 
CAGCAGCCTG CAGAGAGAGC CCTGAGAACG CCAGCCAAGC GGGGTACGCA GTCAGTGCTC 
AGAGTGTCCC AGCTGCTGCT CAGGGCCATT GCTGGCCACC AGCACCTGAC TCTGGATGCG 
CTCAAGAAGG AGCTGGGAAA CGCCGGCTAC GAAGTGCGCC GGGAGATCTC CTCTCACCAC 
GAGGGGAAGT CCACCAGGTT GGAGAAAGGC ACGCTCCTGA GGGTCAGTGG CAGCGACGCT 
GCTGGCTACT TCAGGGTCTG GAAGATTTCA AAGCCGAGGG AAAAGGCGGG ACAATCCCGG 
TTGACGCTGG GCAGCCACTC TTCTGGGAAG ACCGTGCTCA AATCCCCCAG ACCACTCAGG 
CCCCGCTCGC GTCGCAAGGC AGCCAAGAAG GCCAGAGAAG TCTGGAGACG CAAGGCCAGG 
GCTTTGAAGG CAAGGTCCAG GAGGGTCAGA ACAAGGTCCA CATCAGGGGC CAGATCAAGG 
ACCAGGTCAA GAGCCTCTTC AAGGGCCACT TCAAGGGCCA CATCAAGGGC CAGATCAAGA 
GCCCGGTCAA GGGCCCAGTC AAGTGCCAGA TCAAGCGCCA GGTCAAGCGC CAAGTCAAGC 
GCCAAGTCAA GCACCAGGTC TAGCGCCAAG TCATGGGCCA GGTCAAAGGC TAGGTCAAGG 
GCAAGGTCTA GAGCTAAGGA CCTAGTGCGT TCCAAAGCCC GGGAACAGGC TCAGGCCAGG 
GAACAGGCTC GTGCTAGAGC CAGGGAACAG GCTCATGCCA GAGCCAGGAC ACAAGACTGG 
GTCAGGGCCA AGGCACAGGA GTTTGTCAGT GCCAAAGAGC AGCAGTACGT CAGAGCCAAG 
GAGCAGGAGC GTGCCAAGGC CAGGGAACAG GTGCGTATCG GAGCCAGGGA TGAAGCCAGG 
ATCAAGGCAA AAGATTACAA CAGAGTACGG CCTACAAAGG AAGACACCAG TCCTAGGCCA 
GCAGAGGAGA AGAGTTCAAA CTCCAAACTC AGGGAAGAGA AGGGACAGGA ACCCGAGAGG 
CCAGTAAAAC AGACCATCCA GAAACCAGCT CTGGACAACG CTCCCAGCAT ACAAGGAAAA 
GCATGCACAA AGTCTTTTAC CAAAAGTGGT CAGCCTGGGG ACACTGAGTC TCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081580.2
CDS	42..1238
Translation	MAEAVQPSGESQGAELTIQIQQPAERALRTPAKRGTQSVLRVSQLLLRAIAGHQHLTLDALKKELGNAGYEVRREISSHHEGKSTRLEKGTLLRVSGSDAAGYFRVWKISKPREKAGQSRLTLGSHSSGKTVLKSPRPLRPRSRRKAAKKAREVWRRKARALKARSRRVRTRSTSGARSRTRSRASSRATSRATSRARSRARSRAQSSARSSARSSAKSSAKSSTRSSAKSWARSKARSRARSRAKDLVRSKAREQAQAREQARARAREQAHARARTQDWVRAKAQEFVSAKEQQYVRAKEQERAKAREQVRIGARDEARIKAKDYNRVRPTKEDTSPRPAEEKSSNSKLREEKGQEPERPVKQTIQKPALDNAPSIQGKACTKSFTKSGQPGDTESP

Target ORF information:

RefSeq Version	NM_027304.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus H1.7 linker histone (H1f7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027304.2

ORF Insert Sequence:

ATGGCTGAGG CTGTCCAGCC CAGTGGGGAA TCCCAAGGCG CAGAACTTAC GATCCAGATC 
CAGCAGCCTG CAGAGAGAGC CCTGAGAACG CCAGCCAAGC GGGGTACGCA GTCAGTGCTC 
AGAGTGTCCC AGCTGCTGCT CAGGGCCATT GCTGGCCACC AGCACCTGAC TCTGGATGCG 
CTCAAGAAGG AGCTGGGAAA CGCCGGCTAC GAAGTGCGCC GGGAGATCTC CTCTCACCAC 
GAGGGGAAGT CCACCAGGTT GGAGAAAGGC ACGCTCCTGA GGGTCAGTGG CAGCGACGCT 
GCTGGCTACT TCAGGGTCTG GAAGATTTCA AAGCCGAGGG AAAAGGCGGG ACAATCCCGG 
TTGACGCTGG GCAGCCACTC TTCTGGGAAG ACCGTGCTCA AATCCCCCAG ACCACTCAGG 
CCCCGCTCGC GTCGCAAGGC AGCCAAGAAG GCCAGAGAAG TCTGGAGACG CAAGGCCAGG 
GCTTTGAAGG CAAGGTCCAG GAGGGTCAGA ACAAGGTCCA CATCAGGGGC CAGATCAAGG 
ACCAGGTCAA GAGCCTCTTC AAGGGCCACT TCAAGGGCCA CATCAAGGGC CAGATCAAGA 
GCCCGGTCAA GGGCCCAGTC AAGTGCCAGA TCAAGCGCCA GGTCAAGCGC CAAGTCAAGC 
GCCAAGTCAA GCACCAGGTC TAGCGCCAAG TCATGGGCCA GGTCAAAGGC TAGGTCAAGG 
GCAAGGTCTA GAGCTAAGGA CCTAGTGCGT TCCAAAGCCC GGGAACAGGC TCAGGCCAGG 
GAACAGGCTC GTGCTAGAGC CAGGGAACAG GCTCATGCCA GAGCCAGGAC ACAAGACTGG 
GTCAGGGCCA AGGCACAGGA GTTTGTCAGT GCCAAAGAGC AGCAGTACGT CAGAGCCAAG 
GAGCAGGAGC GTGCCAAGGC CAGGGAACAG GTGCGTATCG GAGCCAGGGA TGAAGCCAGG 
ATCAAGGCAA AAGATTACAA CAGAGTACGG CCTACAAAGG AAGACACCAG TCCTAGGCCA 
GCAGAGGAGA AGAGTTCAAA CTCCAAACTC AGGGAAGAGA AGGGACAGGA ACCCGAGAGG 
CCAGTAAAAC AGACCATCCA GAAACCAGCT CTGGACAACG CTCCCAGCAT ACAAGGAAAA 
GCATGCACAA AGTCTTTTAC CAAAAGTGGT CAGCCTGGGG ACACTGAGTC TCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of H1 linker histones in mammalian development and stem cell differentiation.
Biochimica et biophysica acta1859(3)496-509(2016 Mar)
Pan C,Fan Y

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice.
PLoS genetics11(2)e1004964(2015 Feb)
Tang MC,Jacobs SA,Mattiske DM,Soh YM,Graham AN,Tran A,Lim SL,Hudson DF,Kalitsis P,O'Bryan MK,Wong LH,Mann JR

Histone variants: key players of chromatin.
Cell and tissue research356(3)457-66(2014 Jun)
Biterge B,Schneider R

A unified phylogeny-based nomenclature for histone variants.
Epigenetics & chromatin57(2012 Jun)
Talbert PB,Ahmad K,Almouzni G,Ausi? J,Berger F,Bhalla PL,Bonner WM,Cande WZ,Chadwick BP,Chan SW,Cross GA,Cui L,Dimitrov SI,Doenecke D,Eirin-L?pez JM,Gorovsky MA,Hake SB,Hamkalo BA,Holec S,Jacobsen SE,Kamieniarz K,Khochbin S,Ladurner AG,Landsman D,Latham JA,Loppin B,Malik HS,Marzluff WF,Pehrson JR,Postberg J,Schneider R,Singh MB,Smith MM,Thompson E,Torres-Padilla ME,Tremethick DJ,Turner BM,Waterborg JH,Wollmann H,Yelagandula R,Zhu B,Henikoff S

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H1f7 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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