Clec4b1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clec4b1
Entrez Gene ID	69810
Full Name	C-type lectin domain family 4, member b1
Synonyms	1810046I24Rik,Aplra2,Clec4b,DCAR,DCARbeta,Dcar2
General protein information	Preferred Names C-type lectin domain family 4, member b1 Names C-type lectin domain family 4, member b1 antigen presenting cell lectin-like receptor A2 dendritic cell immunoactivating receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 F2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001190310.1	NP_001177239.1	C-type lectin domain family 4, member b1 isoform 1
XM_006506570.1	XP_006506633.1	C-type lectin domain family 4, member b1 isoform X1
NM_027218.3	NP_081494.1	C-type lectin domain family 4, member b1 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Clec4b1	NP_001177239.1
Pan troglodytes (chimpanzee)	CLEC4C	XP_003952146.1
	LOC100424643	XP_002798519.1
Homo sapiens (human)	CLEC4C	NP_569708.1

Gene Ontology
Bibliography

Related articles in PubMed

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection.
Toyonaga K, Torigoe S, Motomura Y, Kamichi T, Hayashi JM, Morita YS, Noguchi N, Chuma Y, Kiyohara H, Matsuo K, Tanaka H, Nakagawa Y, Sakuma T, Ohmuraya M, Yamamoto T, Umemura M, Matsuzaki G, Yoshikai Y, Yano I, Miyamoto T, Yamasaki S
Immunity45(6)1245-1257(2016 12)

Ubiquitous versus restricted expression of the two mouse dendritic cell C-type lectin receptors, DCIR1 and DCAR2, among myeloid cells.
Kishimoto A, Watanabe M, Terauchi K, Kojima T, Kameda Y, Yamamoto K, Matsumoto N
Biochemical and biophysical research communications467(2)383-8(2015 Nov)

Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing.
Nakagawa Y, Sakuma T, Nakagata N, Yamasaki S, Takeda N, Ohmuraya M, Yamamoto T
Experimental animals63(3)349-55(2014)

Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex.
Flornes LM, Bryceson YT, Spurkland A, Lorentzen JC, Dissen E, Fossum S
Immunogenetics56(7)506-17(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DCAR is a critical receptor for phosphatidyl-inositol mannosides that functions to promote T cell responses against mycobacteria
Title: C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection.

While DCIR1 was ubiquitously expressed on myeloid cells in various immune organs, significant expression of DCAR2 was detected only on subpopulations of conventional dendritic cells from bone marrow and skin-draining lymph nodes.
Title: Ubiquitous versus restricted expression of the two mouse dendritic cell C-type lectin receptors, DCIR1 and DCAR2, among myeloid cells.

identifed a novel C-type lectin receptor, dendritic cell immunoactivating receptor (DCAR), whose extracellular lectin domain is highly homologous to that of dendritic cell immunoreceptor(DCIR) [DCAR]
Title: Dendritic cell immunoactivating receptor, a novel C-type lectin immunoreceptor, acts as an activating receptor through association with Fc receptor gamma chain.

The following Clec4b1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clec4b1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01252	NM_001190310.1 Latest version!	Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu03887	NM_027218.3 Latest version!	Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu37561	XM_006506570.1 Latest version!	Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clec4b1 ( NM_001190310.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001177239.1 Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu01252
Clone ID Related Accession (Same CDS sequence)	NM_001190310.1
Accession Version	NM_001190310.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 4, member b1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124337.15. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY365134.1, AY230259.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTTCAGG AAAGACAGCT ACAAGGGAAG GCAGTCTCCT GGTCCCTGAG ACTCTGGTCA 
GCTGCTGTGA TTTCTATCTT ACTCCTCAGC ACCTGTTTCA TTGCGAGCTG TGTGGTCACT 
TACCAGTTTA GTATGGACAA GCCAAATAGA AGACTATCTG AACTTGACAG GTACCATTCA 
TTGACCTGCT TCAGTGAAGG GAATATGGTG TCAGACAAAG TCTGGAGCTG TTGCCCAAAG 
GATTGGAAGC TATTTGGTTC CCACTGCTAC TTGGTTCCCA CAGTTTTTTC ATCAGCATCT 
TGGAACAAGA GTGAGGAGAA CTGCTCCCGC ATGGGTGCTC ATCTAGTGGT GATCCATAGC 
CAGGAGGAGC AGGATTTCAT CACTGGGATC TTGGACATTC ATGCTGCTTA TTTTATAGGG 
TTGTGGGATA CAGGCCATCG GCAATGGCAA TGGGTTGATC AGACACCATA TGAAGAAAGT 
GTCACATTCT GGCACAATGG TGAGCCCAGC AGTGACAATG AAAAATGTGT TACAGTATAT 
TACCGTCGGA ATATTGGATG GGGCTGGAAT GATATCTCTT GCAATCTTAA ACAGAAGTCA 
GTTTGTCAGA TGAAGAAAAT AAACTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177239.1
CDS	137..766
Translation	MVQERQLQGKAVSWSLRLWSAAVISILLLSTCFIASCVVTYQFSMDKPNRRLSELDRYHSLTCFSEGNMVSDKVWSCCPKDWKLFGSHCYLVPTVFSSASWNKSEENCSRMGAHLVVIHSQEEQDFITGILDIHAAYFIGLWDTGHRQWQWVDQTPYEESVTFWHNGEPSSDNEKCVTVYYRRNIGWGWNDISCNLKQKSVCQMKKINL

Target ORF information:

RefSeq Version	NM_001190310.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190310.1

ORF Insert Sequence:

ATGGTTCAGG AAAGACAGCT ACAAGGGAAG GCAGTCTCCT GGTCCCTGAG ACTCTGGTCA 
GCTGCTGTGA TTTCTATCTT ACTCCTCAGC ACCTGTTTCA TTGCGAGCTG TGTGGTCACT 
TACCAGTTTA GTATGGACAA GCCAAATAGA AGACTATCTG AACTTGACAG GTACCATTCA 
TTGACCTGCT TCAGTGAAGG GAATATGGTG TCAGACAAAG TCTGGAGCTG TTGCCCAAAG 
GATTGGAAGC TATTTGGTTC CCACTGCTAC TTGGTTCCCA CAGTTTTTTC ATCAGCATCT 
TGGAACAAGA GTGAGGAGAA CTGCTCCCGC ATGGGTGCTC ATCTAGTGGT GATCCATAGC 
CAGGAGGAGC AGGATTTCAT CACTGGGATC TTGGACATTC ATGCTGCTTA TTTTATAGGG 
TTGTGGGATA CAGGCCATCG GCAATGGCAA TGGGTTGATC AGACACCATA TGAAGAAAGT 
GTCACATTCT GGCACAATGG TGAGCCCAGC AGTGACAATG AAAAATGTGT TACAGTATAT 
TACCGTCGGA ATATTGGATG GGGCTGGAAT GATATCTCTT GCAATCTTAA ACAGAAGTCA 
GTTTGTCAGA TGAAGAAAAT AAACTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clec4b1 ( NM_027218.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081494.1 Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu03887
Clone ID Related Accession (Same CDS sequence)	NM_027218.3
Accession Version	NM_027218.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 4, member b1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AA914236.1, AK007794.1 and AC124337.15. On Jun 15, 2010 this sequence version replaced NM_027218.2. Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY230260.1, BY707802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTTCAGG AAAGACAGCT ACAAGGGAAG GCAGTCTCCT GGTCCCTGAG ACTCTGGTCA 
GCTGCTGTGA TTTCTATCTT ACTCCTCAGC ACCTGTTTCA TTGCGAGCTG TGTGGACAAA 
GTCTGGAGCT GTTGCCCAAA GGATTGGAAG CTATTTGGTT CCCACTGCTA CTTGGTTCCC 
ACAGTTTTTT CATCAGCATC TTGGAACAAG AGTGAGGAGA ACTGCTCCCG CATGGGTGCT 
CATCTAGTGG TGATCCATAG CCAGGAGGAG CAGGATTTCA TCACTGGGAT CTTGGACATT 
CATGCTGCTT ATTTTATAGG GTTGTGGGAT ACAGGCCATC GGCAATGGCA ATGGGTTGAT 
CAGACACCAT ATGAAGAAAG TGTCACATTC TGGCACAATG GTGAGCCCAG CAGTGACAAT 
GAAAAATGTG TTACAGTATA TTACCGTCGG AATATTGGAT GGGGCTGGAA TGATATCTCT 
TGCAATCTTA AACAGAAGTC AGTTTGTCAG ATGAAGAAAA TAAACTTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081494.1
CDS	137..667
Translation	MVQERQLQGKAVSWSLRLWSAAVISILLLSTCFIASCVDKVWSCCPKDWKLFGSHCYLVPTVFSSASWNKSEENCSRMGAHLVVIHSQEEQDFITGILDIHAAYFIGLWDTGHRQWQWVDQTPYEESVTFWHNGEPSSDNEKCVTVYYRRNIGWGWNDISCNLKQKSVCQMKKINL

Target ORF information:

RefSeq Version	NM_027218.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027218.3

ORF Insert Sequence:

ATGGTTCAGG AAAGACAGCT ACAAGGGAAG GCAGTCTCCT GGTCCCTGAG ACTCTGGTCA 
GCTGCTGTGA TTTCTATCTT ACTCCTCAGC ACCTGTTTCA TTGCGAGCTG TGTGGACAAA 
GTCTGGAGCT GTTGCCCAAA GGATTGGAAG CTATTTGGTT CCCACTGCTA CTTGGTTCCC 
ACAGTTTTTT CATCAGCATC TTGGAACAAG AGTGAGGAGA ACTGCTCCCG CATGGGTGCT 
CATCTAGTGG TGATCCATAG CCAGGAGGAG CAGGATTTCA TCACTGGGAT CTTGGACATT 
CATGCTGCTT ATTTTATAGG GTTGTGGGAT ACAGGCCATC GGCAATGGCA ATGGGTTGAT 
CAGACACCAT ATGAAGAAAG TGTCACATTC TGGCACAATG GTGAGCCCAG CAGTGACAAT 
GAAAAATGTG TTACAGTATA TTACCGTCGG AATATTGGAT GGGGCTGGAA TGATATCTCT 
TGCAATCTTA AACAGAAGTC AGTTTGTCAG ATGAAGAAAA TAAACTTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clec4b1 ( XM_006506570.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506633.1 Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37561
Clone ID Related Accession (Same CDS sequence)	XM_006506570.1
Accession Version	XM_006506570.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 4, member b1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACAAGC CAAATAGAAG ACTATCTGAA CTTGACAGGT ACCATTCATT GACCTGCTTC 
AGTGAAGGGA ATATGGTGTC AGACAAAGTC TGGAGCTGTT GCCCAAAGGA TTGGAAGCTA 
TTTGGTTCCC ACTGCTACTT GGTTCCCACA GTTTTTTCAT CAGCATCTTG GAACAAGAGT 
GAGGAGAACT GCTCCCGCAT GGGTGCTCAT CTAGTGGTGA TCCATAGCCA GGAGGAGCAG 
GATTTCATCA CTGGGATCTT GGACATTCAT GCTGCTTATT TTATAGGGTT GTGGGATACA 
GGCCATCGGC AATGGCAATG GGTTGATCAG ACACCATATG AAGAAAGTGT CACATTCTGG 
CACAATGGTG AGCCCAGCAG TGACAATGAA AAATGTGTTA CAGTATATTA CCGTCGGAAT 
ATTGGATGGG GCTGGAATGA TATCTCTTGC AATCTTAAAC AGAAGTCAGT TTGTCAGATG 
AAGAAAATAA ACTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506633.1
CDS	173..670
Translation	MDKPNRRLSELDRYHSLTCFSEGNMVSDKVWSCCPKDWKLFGSHCYLVPTVFSSASWNKSEENCSRMGAHLVVIHSQEEQDFITGILDIHAAYFIGLWDTGHRQWQWVDQTPYEESVTFWHNGEPSSDNEKCVTVYYRRNIGWGWNDISCNLKQKSVCQMKKINL

Target ORF information:

RefSeq Version	XM_006506570.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 4, member b1 (Clec4b1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506570.1

ORF Insert Sequence:

ATGGACAAGC CAAATAGAAG ACTATCTGAA CTTGACAGGT ACCATTCATT GACCTGCTTC 
AGTGAAGGGA ATATGGTGTC AGACAAAGTC TGGAGCTGTT GCCCAAAGGA TTGGAAGCTA 
TTTGGTTCCC ACTGCTACTT GGTTCCCACA GTTTTTTCAT CAGCATCTTG GAACAAGAGT 
GAGGAGAACT GCTCCCGCAT GGGTGCTCAT CTAGTGGTGA TCCATAGCCA GGAGGAGCAG 
GATTTCATCA CTGGGATCTT GGACATTCAT GCTGCTTATT TTATAGGGTT GTGGGATACA 
GGCCATCGGC AATGGCAATG GGTTGATCAG ACACCATATG AAGAAAGTGT CACATTCTGG 
CACAATGGTG AGCCCAGCAG TGACAATGAA AAATGTGTTA CAGTATATTA CCGTCGGAAT 
ATTGGATGGG GCTGGAATGA TATCTCTTGC AATCTTAAAC AGAAGTCAGT TTGTCAGATG 
AAGAAAATAA ACTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection.
Immunity45(6)1245-1257(2016 12)
Toyonaga K,Torigoe S,Motomura Y,Kamichi T,Hayashi JM,Morita YS,Noguchi N,Chuma Y,Kiyohara H,Matsuo K,Tanaka H,Nakagawa Y,Sakuma T,Ohmuraya M,Yamamoto T,Umemura M,Matsuzaki G,Yoshikai Y,Yano I,Miyamoto T,Yamasaki S

Ubiquitous versus restricted expression of the two mouse dendritic cell C-type lectin receptors, DCIR1 and DCAR2, among myeloid cells.
Biochemical and biophysical research communications467(2)383-8(2015 Nov)
Kishimoto A,Watanabe M,Terauchi K,Kojima T,Kameda Y,Yamamoto K,Matsumoto N

Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing.
Experimental animals63(3)349-55(2014)
Nakagawa Y,Sakuma T,Nakagata N,Yamasaki S,Takeda N,Ohmuraya M,Yamamoto T

Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex.
Immunogenetics56(7)506-17(2004 Oct)
Flornes LM,Bryceson YT,Spurkland A,Lorentzen JC,Dissen E,Fossum S

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Clec4b1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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