Tnfsf13 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnfsf13
Entrez Gene ID	69583
Full Name	tumor necrosis factor (ligand) superfamily, member 13
Synonyms	2310026N09Rik,April,Tall2,Tnlg7b,Trdl1
General protein information	Preferred Names tumor necrosis factor (ligand) superfamily, member 13 Names tumor necrosis factor ligand superfamily member 13 a proliferation-inducing ligand tumor necrosis factor ligand 7b
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001159505.1	NP_001152977.1	tumor necrosis factor ligand superfamily member 13 isoform 2
NM_023517.2	NP_076006.2	tumor necrosis factor ligand superfamily member 13 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TNFSF13	NP_001192059.1
Mus musculus (house mouse)	Tnfsf13	NP_076006.2
Homo sapiens (human)	TNFSF13	NP_003799.1
Canis lupus familiaris (dog)	TNFSF13	NP_001192098.1
Bos taurus (cattle)	TNFSF13	NP_001029819.1
Rattus norvegicus (Norway rat)	Tnfsf13	NP_001009623.1
Xenopus tropicalis (tropical clawed frog)	LOC101730941	XP_004919464.1

Gene Ontology
Bibliography

Related articles in PubMed

TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo.
McWilliams TG, Howard L, Wyatt S, Davies AM
Experimental neurology298(Pt A)97-103(2017 Dec)

CD138 mediates selection of mature plasma cells by regulating their survival.
McCarron MJ, Park PW, Fooksman DR
Blood129(20)2749-2759(2017 05)

TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.
Tran NL, Schneider P, Santiago-Raber ML
European journal of immunology47(4)713-723(2017 04)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study identifies APRIL as a new target involved in B-cell activation, in the maintenance of plasma cell survival and subsequent increased autoantibody production that sustains lupus development in mice
Title: TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.

p40, a Lactobacillus rhamnosus-derived protein upregulates EGFR-dependent APRIL expression in intestinal epithelial cells, which may contribute to promoting IgA production
Title: An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells.

Our data indicate that APRIL contributes to fibrotic scar formation after spinal cord injury by mediating the inflammatory response
Title: Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury.

the elevated presence of APRIL and BLyS in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL-expressing B cells/plasma cells.
Title: The B Cell-Stimulatory Cytokines BLyS and APRIL Are Elevated in Human Periodontitis and Are Required for B Cell-Dependent Bone Loss in Experimental Murine Periodontitis.

this is the first study to implicate the APRIL signal transduction pathway in the pathogenesis of nephrogenic IgA production. Moreover, our findings identify APRIL as a potential target of therapy.
Title: Pathogenic Role of a Proliferation-Inducing Ligand (APRIL) in Murine IgA Nephropathy.

The following Tnfsf13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnfsf13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07488	NM_001159505.1 Latest version!	Mus musculus tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OMu03664	NM_023517.2 Latest version!	Mus musculus tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnfsf13 ( NM_001159505.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001152977.1 Mus musculus tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu07488
Clone ID Related Accession (Same CDS sequence)	NM_001159505.1
Accession Version	NM_001159505.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	tumor necrosis factor ligand superfamily member 13 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK009514.1, AK134028.1 and AL603707.5. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) lacks one internal aa, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK134028.1, AK170351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAGCCT CATCTCCAGG CCACATGGGG GGCTCAGTCA GAGAGCCAGC CCTTTCGGTT 
GCTCTTTGGT TGAGTTGGGG GGCAGTTCTG GGGGCTGTGA CTTGTGCTGT CGCACTACTG 
ATCCAACAGA CAGAGCTGCA AAGCCTAAGG CGGGAGGTGA GCCGGCTGCA GCGGAGTGGA 
GGGCCTTCCC AGAAGCAGGG AGAGCGCCCA TGGCAGAGCC TCTGGGAGCA GAGTCCTGAT 
GTCCTGGAAG CCTGGAAGGA TGGGGCGAAA TCTCGGAGAA GGAGAGCAGT ACTCACCCAG 
AAGCACAAGA AGAAGCACTC AGTCCTGCAT CTTGTTCCAG TTAACATTAC CTCCAAGGAC 
TCTGACGTGA CAGAGGTGAT GTGGCAACCA GTACTTAGGC GTGGGAGAGG CCTGGAGGCC 
CAGGGAGACA TTGTACGAGT CTGGGACACT GGAATTTATC TGCTCTATAG TCAGGTCCTG 
TTTCATGATG TGACTTTCAC AATGGGTCAG GTGGTATCTC GGGAAGGACA AGGGAGAAGA 
GAAACTCTAT TCCGATGTAT CAGAAGTATG CCTTCTGATC CTGACCGTGC CTACAATAGC 
TGCTACAGTG CAGGTGTCTT TCATTTACAT CAAGGGGATA TTATCACTGT CAAAATTCCA 
CGGGCAAACG CAAAACTTAG CCTTTCTCCG CATGGAACAT TCCTGGGGTT TGTGAAACTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152977.1
CDS	296..1018
Translation	MPASSPGHMGGSVREPALSVALWLSWGAVLGAVTCAVALLIQQTELQSLRREVSRLQRSGGPSQKQGERPWQSLWEQSPDVLEAWKDGAKSRRRRAVLTQKHKKKHSVLHLVPVNITSKDSDVTEVMWQPVLRRGRGLEAQGDIVRVWDTGIYLLYSQVLFHDVTFTMGQVVSREGQGRRETLFRCIRSMPSDPDRAYNSCYSAGVFHLHQGDIITVKIPRANAKLSLSPHGTFLGFVKL

Target ORF information:

RefSeq Version	NM_001159505.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159505.1

ORF Insert Sequence:

ATGCCAGCCT CATCTCCAGG CCACATGGGG GGCTCAGTCA GAGAGCCAGC CCTTTCGGTT 
GCTCTTTGGT TGAGTTGGGG GGCAGTTCTG GGGGCTGTGA CTTGTGCTGT CGCACTACTG 
ATCCAACAGA CAGAGCTGCA AAGCCTAAGG CGGGAGGTGA GCCGGCTGCA GCGGAGTGGA 
GGGCCTTCCC AGAAGCAGGG AGAGCGCCCA TGGCAGAGCC TCTGGGAGCA GAGTCCTGAT 
GTCCTGGAAG CCTGGAAGGA TGGGGCGAAA TCTCGGAGAA GGAGAGCAGT ACTCACCCAG 
AAGCACAAGA AGAAGCACTC AGTCCTGCAT CTTGTTCCAG TTAACATTAC CTCCAAGGAC 
TCTGACGTGA CAGAGGTGAT GTGGCAACCA GTACTTAGGC GTGGGAGAGG CCTGGAGGCC 
CAGGGAGACA TTGTACGAGT CTGGGACACT GGAATTTATC TGCTCTATAG TCAGGTCCTG 
TTTCATGATG TGACTTTCAC AATGGGTCAG GTGGTATCTC GGGAAGGACA AGGGAGAAGA 
GAAACTCTAT TCCGATGTAT CAGAAGTATG CCTTCTGATC CTGACCGTGC CTACAATAGC 
TGCTACAGTG CAGGTGTCTT TCATTTACAT CAAGGGGATA TTATCACTGT CAAAATTCCA 
CGGGCAAACG CAAAACTTAG CCTTTCTCCG CATGGAACAT TCCTGGGGTT TGTGAAACTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tnfsf13 ( NM_023517.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_076006.2 Mus musculus tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu03664
Clone ID Related Accession (Same CDS sequence)	NM_023517.2
Accession Version	NM_023517.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	tumor necrosis factor ligand superfamily member 13 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK009514.1, AK134028.1 and BY463961.1. On Oct 13, 2005 this sequence version replaced NM_023517.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK009514.1, BC069900.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAGCCT CATCTCCAGG CCACATGGGG GGCTCAGTCA GAGAGCCAGC CCTTTCGGTT 
GCTCTTTGGT TGAGTTGGGG GGCAGTTCTG GGGGCTGTGA CTTGTGCTGT CGCACTACTG 
ATCCAACAGA CAGAGCTGCA AAGCCTAAGG CGGGAGGTGA GCCGGCTGCA GCGGAGTGGA 
GGGCCTTCCC AGAAGCAGGG AGAGCGCCCA TGGCAGAGCC TCTGGGAGCA GAGTCCTGAT 
GTCCTGGAAG CCTGGAAGGA TGGGGCGAAA TCTCGGAGAA GGAGAGCAGT ACTCACCCAG 
AAGCACAAGA AGAAGCACTC AGTCCTGCAT CTTGTTCCAG TTAACATTAC CTCCAAGGCA 
GACTCTGACG TGACAGAGGT GATGTGGCAA CCAGTACTTA GGCGTGGGAG AGGCCTGGAG 
GCCCAGGGAG ACATTGTACG AGTCTGGGAC ACTGGAATTT ATCTGCTCTA TAGTCAGGTC 
CTGTTTCATG ATGTGACTTT CACAATGGGT CAGGTGGTAT CTCGGGAAGG ACAAGGGAGA 
AGAGAAACTC TATTCCGATG TATCAGAAGT ATGCCTTCTG ATCCTGACCG TGCCTACAAT 
AGCTGCTACA GTGCAGGTGT CTTTCATTTA CATCAAGGGG ATATTATCAC TGTCAAAATT 
CCACGGGCAA ACGCAAAACT TAGCCTTTCT CCGCATGGAA CATTCCTGGG GTTTGTGAAA 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076006.2
CDS	296..1021
Translation	MPASSPGHMGGSVREPALSVALWLSWGAVLGAVTCAVALLIQQTELQSLRREVSRLQRSGGPSQKQGERPWQSLWEQSPDVLEAWKDGAKSRRRRAVLTQKHKKKHSVLHLVPVNITSKADSDVTEVMWQPVLRRGRGLEAQGDIVRVWDTGIYLLYSQVLFHDVTFTMGQVVSREGQGRRETLFRCIRSMPSDPDRAYNSCYSAGVFHLHQGDIITVKIPRANAKLSLSPHGTFLGFVKL

Target ORF information:

RefSeq Version	NM_023517.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023517.2

ORF Insert Sequence:

ATGCCAGCCT CATCTCCAGG CCACATGGGG GGCTCAGTCA GAGAGCCAGC CCTTTCGGTT 
GCTCTTTGGT TGAGTTGGGG GGCAGTTCTG GGGGCTGTGA CTTGTGCTGT CGCACTACTG 
ATCCAACAGA CAGAGCTGCA AAGCCTAAGG CGGGAGGTGA GCCGGCTGCA GCGGAGTGGA 
GGGCCTTCCC AGAAGCAGGG AGAGCGCCCA TGGCAGAGCC TCTGGGAGCA GAGTCCTGAT 
GTCCTGGAAG CCTGGAAGGA TGGGGCGAAA TCTCGGAGAA GGAGAGCAGT ACTCACCCAG 
AAGCACAAGA AGAAGCACTC AGTCCTGCAT CTTGTTCCAG TTAACATTAC CTCCAAGGCA 
GACTCTGACG TGACAGAGGT GATGTGGCAA CCAGTACTTA GGCGTGGGAG AGGCCTGGAG 
GCCCAGGGAG ACATTGTACG AGTCTGGGAC ACTGGAATTT ATCTGCTCTA TAGTCAGGTC 
CTGTTTCATG ATGTGACTTT CACAATGGGT CAGGTGGTAT CTCGGGAAGG ACAAGGGAGA 
AGAGAAACTC TATTCCGATG TATCAGAAGT ATGCCTTCTG ATCCTGACCG TGCCTACAAT 
AGCTGCTACA GTGCAGGTGT CTTTCATTTA CATCAAGGGG ATATTATCAC TGTCAAAATT 
CCACGGGCAA ACGCAAAACT TAGCCTTTCT CCGCATGGAA CATTCCTGGG GTTTGTGAAA 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo.
Experimental neurology298(Pt A)97-103(2017 Dec)
McWilliams TG,Howard L,Wyatt S,Davies AM

CD138 mediates selection of mature plasma cells by regulating their survival.
Blood129(20)2749-2759(2017 05)
McCarron MJ,Park PW,Fooksman DR

TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.
European journal of immunology47(4)713-723(2017 04)
Tran NL,Schneider P,Santiago-Raber ML

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Tnfsf13 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報