Mpzl1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mpzl1
Entrez Gene ID	68481
Full Name	myelin protein zero-like 1
Synonyms	1110007A10Rik,PZR
General protein information	Preferred Names myelin protein zero-like 1 Names myelin protein zero-like protein 1 protein zero-related
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 H2.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001347128.1	NP_001334057.1	myelin protein zero-like protein 1 isoform c precursor
NM_001083897.1	NP_001077366.1	myelin protein zero-like protein 1 isoform a precursor
NM_001001880.2	NP_001001880.1	myelin protein zero-like protein 1 isoform b precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MPZL1	XP_524952.3
Bos taurus (cattle)	MPZL1	NP_001069626.1
Mus musculus (house mouse)	Mpzl1	NP_001077366.1
Gallus gallus (chicken)	MPZL1	XP_416652.4
Canis lupus familiaris (dog)	MPZL1	XP_537211.3
Rattus norvegicus (Norway rat)	Mpzl1	NP_001007729.1
Xenopus tropicalis (tropical clawed frog)	mpzl1	XP_004912325.1
	MPZL1	XP_001089242.1
Danio rerio (zebrafish)	mpzl1l	NP_001244269.1
Homo sapiens (human)	MPZL1	NP_003944.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.
Leiva AG, Chen AL, Devarajan P, Chen Z, Damanpour S, Hall JA, Bianco AC, Li J, Badiavas EV, Zaias J, Miteva M, Romanelli P, Nouri K, Cao Wikramanayake T
The Journal of investigative dermatology134(7)1817-1827(2014 Jul)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation.
Eminaga S, Bennett AM
The Journal of biological chemistry283(22)15328-38(2008 May)

Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells.
Kusano K, Thomas TN, Fujiwara K
Endothelium : journal of endothelial cell research15(3)127-36(2008 May-Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data reveal a complex role for Mpzl3 in the control of skin development, hair growth, and adipose cell functions.
Title: Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.

SIRPalpha and PZR serve as scaffolds that facilitate plasma membrane recruitment and signaling of NS-associated SHP-2 mutants.
Title: Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation.

Phosphorylation and localization of PZR in cultufred endothelial cells is reported.
Title: Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells.

describe the function of the mPZR isoforms in vivo, particularly with respect to their roles in regulating SHP-2-dependent cell migration during development.
Title: The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation.

The following Mpzl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mpzl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu28832	NM_001347128.1 Latest version!	Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu02823	NM_001083897.1 Latest version!	Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu10415	NM_001001880.2 Latest version!	Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mpzl1 ( NM_001347128.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334057.1 Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu28832
Clone ID Related Accession (Same CDS sequence)	NM_001347128.1
Accession Version	NM_001347128.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	myelin protein zero-like protein 1 isoform c precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102776.10. On Nov 16, 2016 this sequence version replaced XM_006496974.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CO804764.1, BE304068.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164133 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGAGG CCGTCGGAGC CGTGGCACTG ATTGCGGCCC CGGCCCGCCG GCGCTGGCTG 
TGGTCGGTGC TAGCCGCGAT GCTCGGGCTG TTGACAGCTA GAATATCAGC CTTGGAGGTC 
CATACTCCTA AAGAAATCTT TGTGGTGAAT GGGACACAAG GGAAGCTGAC TTGCACATTC 
GATTCTCCTA ACACAACTGG ATGGTTGACC ACGGTCTCCT GGAGCTTCCA GCCAGACGGC 
ACCGACAGCG CCGTGTCGGG CCCAGTCATT TACGCACAGT TAGACCACTC TGGCGGACAC 
CACAGCGGCA AGATTAATAA GTCAGAGTCG GTTGTGTATG CGGACATCCG GAAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334057.1
CDS	149..508
Translation	MAEAVGAVALIAAPARRRWLWSVLAAMLGLLTARISALEVHTPKEIFVVNGTQGKLTCTFDSPNTTGWLTTVSWSFQPDGTDSAVSGPVIYAQLDHSGGHHSGKINKSESVVYADIRKD

Target ORF information:

RefSeq Version	NM_001347128.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347128.1

ORF Insert Sequence:

ATGGCAGAGG CCGTCGGAGC CGTGGCACTG ATTGCGGCCC CGGCCCGCCG GCGCTGGCTG 
TGGTCGGTGC TAGCCGCGAT GCTCGGGCTG TTGACAGCTA GAATATCAGC CTTGGAGGTC 
CATACTCCTA AAGAAATCTT TGTGGTGAAT GGGACACAAG GGAAGCTGAC TTGCACATTC 
GATTCTCCTA ACACAACTGG ATGGTTGACC ACGGTCTCCT GGAGCTTCCA GCCAGACGGC 
ACCGACAGCG CCGTGTCGGG CCCAGTCATT TACGCACAGT TAGACCACTC TGGCGGACAC 
CACAGCGGCA AGATTAATAA GTCAGAGTCG GTTGTGTATG CGGACATCCG GAAAGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mpzl1 ( NM_001083897.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001077366.1 Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu02823
Clone ID Related Accession (Same CDS sequence)	NM_001083897.1
Accession Version	NM_001083897.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	myelin protein zero-like protein 1 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB871672.1, AK169385.1 and CX210059.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: AK090278.1, AK169385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGAGG CCGTCGGAGC CGTGGCACTG ATTGCGGCCC CGGCCCGCCG GCGCTGGCTG 
TGGTCGGTGC TAGCCGCGAT GCTCGGGCTG TTGACAGCTA GAATATCAGC CTTGGAGGTC 
CATACTCCTA AAGAAATCTT TGTGGTGAAT GGGACACAAG GGAAGCTGAC TTGCACATTC 
GATTCTCCTA ACACAACTGG ATGGTTGACC ACGGTCTCCT GGAGCTTCCA GCCAGACGGC 
ACCGACAGCG CCGTGTCGTT TTTCCACTAC TCACAAGGAC AGGTGTACAT TGGGGATTAT 
CCACCATTTA AAGACCGAGT CACCTGGGCT GGGGACCTTG ACAAGAAAGA TGCATCAATC 
AATATAGAAA ATATTCAGGC TGTTCACAAT GGCACCTATA TCTGCGATGT CAAAAATCCT 
CCTGACATTG TTGTGCGGCC TGGACACATT AGGCTCCACG TGGTGGAAAT AGACAACCTG 
TTGGTGTTCC TGGTTTGGGT GGTGGTGGGC ACTGTCACTG CTGTGGTCCT TGGCCTCACT 
CTGCTCATCA GCTTGGTCCT GGTCGTCCTC TACAGAAGGA AACATTCGAA GCGGGATTAT 
ACCGGCTGCA GTACCTCAGA GCGTTTGTCA CCAGTTAAGC AGGCTCCACG GAAGTGTCCC 
TCCGACACAG AGGGTCTAGT AAAGAGTCCG CCTTCCGCCG GATCTCACCA GGGCCCAGTC 
ATTTACGCAC AGTTAGACCA CTCTGGCGGA CACCACAGCG GCAAGATTAA TAAGTCAGAG 
TCGGTTGTGT ATGCGGACAT CCGGAAAGAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001077366.1
CDS	149..961
Translation	MAEAVGAVALIAAPARRRWLWSVLAAMLGLLTARISALEVHTPKEIFVVNGTQGKLTCTFDSPNTTGWLTTVSWSFQPDGTDSAVSFFHYSQGQVYIGDYPPFKDRVTWAGDLDKKDASINIENIQAVHNGTYICDVKNPPDIVVRPGHIRLHVVEIDNLLVFLVWVVVGTVTAVVLGLTLLISLVLVVLYRRKHSKRDYTGCSTSERLSPVKQAPRKCPSDTEGLVKSPPSAGSHQGPVIYAQLDHSGGHHSGKINKSESVVYADIRKD

Target ORF information:

RefSeq Version	NM_001083897.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001083897.1

ORF Insert Sequence:

ATGGCAGAGG CCGTCGGAGC CGTGGCACTG ATTGCGGCCC CGGCCCGCCG GCGCTGGCTG 
TGGTCGGTGC TAGCCGCGAT GCTCGGGCTG TTGACAGCTA GAATATCAGC CTTGGAGGTC 
CATACTCCTA AAGAAATCTT TGTGGTGAAT GGGACACAAG GGAAGCTGAC TTGCACATTC 
GATTCTCCTA ACACAACTGG ATGGTTGACC ACGGTCTCCT GGAGCTTCCA GCCAGACGGC 
ACCGACAGCG CCGTGTCGTT TTTCCACTAC TCACAAGGAC AGGTGTACAT TGGGGATTAT 
CCACCATTTA AAGACCGAGT CACCTGGGCT GGGGACCTTG ACAAGAAAGA TGCATCAATC 
AATATAGAAA ATATTCAGGC TGTTCACAAT GGCACCTATA TCTGCGATGT CAAAAATCCT 
CCTGACATTG TTGTGCGGCC TGGACACATT AGGCTCCACG TGGTGGAAAT AGACAACCTG 
TTGGTGTTCC TGGTTTGGGT GGTGGTGGGC ACTGTCACTG CTGTGGTCCT TGGCCTCACT 
CTGCTCATCA GCTTGGTCCT GGTCGTCCTC TACAGAAGGA AACATTCGAA GCGGGATTAT 
ACCGGCTGCA GTACCTCAGA GCGTTTGTCA CCAGTTAAGC AGGCTCCACG GAAGTGTCCC 
TCCGACACAG AGGGTCTAGT AAAGAGTCCG CCTTCCGCCG GATCTCACCA GGGCCCAGTC 
ATTTACGCAC AGTTAGACCA CTCTGGCGGA CACCACAGCG GCAAGATTAA TAAGTCAGAG 
TCGGTTGTGT ATGCGGACAT CCGGAAAGAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mpzl1 ( NM_001001880.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001001880.1 Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu10415
Clone ID Related Accession (Same CDS sequence)	NM_001001880.2
Accession Version	NM_001001880.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	myelin protein zero-like protein 1 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB871672.1, BC072563.1 and CX210059.1. On Apr 5, 2007 this sequence version replaced NM_001001880.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform b) has a shorter and distinct C-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.197397.1, BC072563.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164141 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGAGG CCGTCGGAGC CGTGGCACTG ATTGCGGCCC CGGCCCGCCG GCGCTGGCTG 
TGGTCGGTGC TAGCCGCGAT GCTCGGGCTG TTGACAGCTA GAATATCAGC CTTGGAGGTC 
CATACTCCTA AAGAAATCTT TGTGGTGAAT GGGACACAAG GGAAGCTGAC TTGCACATTC 
GATTCTCCTA ACACAACTGG ATGGTTGACC ACGGTCTCCT GGAGCTTCCA GCCAGACGGC 
ACCGACAGCG CCGTGTCGTT TTTCCACTAC TCACAAGGAC AGGTGTACAT TGGGGATTAT 
CCACCATTTA AAGACCGAGT CACCTGGGCT GGGGACCTTG ACAAGAAAGA TGCATCAATC 
AATATAGAAA ATATTCAGGC TGTTCACAAT GGCACCTATA TCTGCGATGT CAAAAATCCT 
CCTGACATTG TTGTGCGGCC TGGACACATT AGGCTCCACG TGGTGGAAAT AGACAACCTG 
TTGGTGTTCC TGGTTTGGGT GGTGGTGGGC ACTGTCACTG CTGTGGTCCT TGGCCTCACT 
CTGCTCATCA GCTTGGTCCT GGTCGTCCTC TACAGAAGGA AACATTCGAA GCGGGATTAT 
ACCGGGGCCC AGTCATTTAC GCACAGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001880.1
CDS	149..778
Translation	MAEAVGAVALIAAPARRRWLWSVLAAMLGLLTARISALEVHTPKEIFVVNGTQGKLTCTFDSPNTTGWLTTVSWSFQPDGTDSAVSFFHYSQGQVYIGDYPPFKDRVTWAGDLDKKDASINIENIQAVHNGTYICDVKNPPDIVVRPGHIRLHVVEIDNLLVFLVWVVVGTVTAVVLGLTLLISLVLVVLYRRKHSKRDYTGAQSFTHS

Target ORF information:

RefSeq Version	NM_001001880.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus myelin protein zero-like 1 (Mpzl1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001880.2

ORF Insert Sequence:

ATGGCAGAGG CCGTCGGAGC CGTGGCACTG ATTGCGGCCC CGGCCCGCCG GCGCTGGCTG 
TGGTCGGTGC TAGCCGCGAT GCTCGGGCTG TTGACAGCTA GAATATCAGC CTTGGAGGTC 
CATACTCCTA AAGAAATCTT TGTGGTGAAT GGGACACAAG GGAAGCTGAC TTGCACATTC 
GATTCTCCTA ACACAACTGG ATGGTTGACC ACGGTCTCCT GGAGCTTCCA GCCAGACGGC 
ACCGACAGCG CCGTGTCGTT TTTCCACTAC TCACAAGGAC AGGTGTACAT TGGGGATTAT 
CCACCATTTA AAGACCGAGT CACCTGGGCT GGGGACCTTG ACAAGAAAGA TGCATCAATC 
AATATAGAAA ATATTCAGGC TGTTCACAAT GGCACCTATA TCTGCGATGT CAAAAATCCT 
CCTGACATTG TTGTGCGGCC TGGACACATT AGGCTCCACG TGGTGGAAAT AGACAACCTG 
TTGGTGTTCC TGGTTTGGGT GGTGGTGGGC ACTGTCACTG CTGTGGTCCT TGGCCTCACT 
CTGCTCATCA GCTTGGTCCT GGTCGTCCTC TACAGAAGGA AACATTCGAA GCGGGATTAT 
ACCGGGGCCC AGTCATTTAC GCACAGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.
The Journal of investigative dermatology134(7)1817-1827(2014 Jul)
Leiva AG,Chen AL,Devarajan P,Chen Z,Damanpour S,Hall JA,Bianco AC,Li J,Badiavas EV,Zaias J,Miteva M,Romanelli P,Nouri K,Cao Wikramanayake T

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation.
The Journal of biological chemistry283(22)15328-38(2008 May)
Eminaga S,Bennett AM

Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells.
Endothelium : journal of endothelial cell research15(3)127-36(2008 May-Jun)
Kusano K,Thomas TN,Fujiwara K

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Mpzl1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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