Ndufa5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ndufa5
Entrez Gene ID	68202
Full Name	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
Synonyms	2900002J19Rik
General protein information	Preferred Names NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 Names NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 CI-13kD-B NADH-ubiquinone oxidoreductase 13 kDa-B subunit complex I subunit B13 complex I-13kD-B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 A3.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_026614.2	NP_080890.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 1
NM_001311068.1	NP_001297997.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 2
NM_001311068.2	NP_001297997.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 2
NM_026614.3	NP_080890.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 1

Pathways from BioSystems

Homologies

	NDUFA5	XP_002803497.1
Pan troglodytes (chimpanzee)	NDUFA5	NP_001065265.1
Rattus norvegicus (Norway rat)	Ndufa5	NP_037117.1
Danio rerio (zebrafish)	ndufa5	NP_001013474.1
Caenorhabditis elegans (roundworm)	CELE_C33A12.1	NP_501688.1
Xenopus tropicalis (tropical clawed frog)	ndufa5	NP_001039265.1
Canis lupus familiaris (dog)	NDUFA5	XP_532446.1
Homo sapiens (human)	NDUFA5	NP_004991.1
Gallus gallus (chicken)	NDUFA5	NP_001091106.1
Drosophila melanogaster (fruit fly)	CG6463	NP_648409.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005621	XP_315631.3
Bos taurus (cattle)	NDUFA5	NP_787023.1
Mus musculus (house mouse)	Ndufa5	NP_080890.1

Gene Ontology
Bibliography

Related articles in PubMed

Chronic Activation of ?2 AMPK Induces Obesity and Reduces ? Cell Function.
Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Mart?nez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, T?th M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H
Cell metabolism23(5)821-36(2016 May)

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Dai N, Zhao L, Wrighting D, Kr?mer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
Cell metabolism21(4)609-21(2015 Apr)

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.
Peralta S, Torraco A, Wenz T, Garcia S, Diaz F, Moraes CT
Human molecular genetics23(6)1399-412(2014 Mar)

Region-specific expression of mitochondrial complex I genes during murine brain development.
Wirtz S, Schuelke M
PloS one6(4)e18897(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

At the age of 11 months, mice with a central nervous system knockout of Ndufa5 (Ndufa5 CNS-KO) showed lethargy and loss of motor skills. In these mice cortices, the levels of NDUFA5 protein were reduced to 25% of controls. Fully assembled complex I (CI) levels were also greatly reduced in cortex and CI activity in homogenates was reduced to 60% of controls.
Title: Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.

The real-time RT-PCR analysis revealed that the expressions of the NDUFA5 mRNA, but not the ZNF9 mRNA level, were significantly up-regulated in all the tested cell lines derived from HPV-positive cervical cancer, HeLa, SW576, and CaSKi.
Title: Identification of NADH dehydrogenase 1 alpha subcomplex 5 capable to transform murine fibroblasts and overexpressed in human cervical carcinoma cell lines.

The following Ndufa5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ndufa5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu70235	NM_001311068.2 Latest version!	Mus musculus NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu14757	NM_026614.3 Latest version!	Mus musculus NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu70235	NM_001311068.1	Mus musculus NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu14757	NM_026614.2	Mus musculus NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ndufa5 ( NM_001311068.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001297997.1 Mus musculus NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu70235
Clone ID Related Accession (Same CDS sequence)	NM_001311068.1 , NM_001311068.2
Accession Version	NM_001311068.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 234bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-09
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY253904.1, BY247454.1 and W66892.1. On Jul 22, 2015 this sequence version replaced XM_006505161.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BU563501.1, BY247454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGGAGC CAGATGTTAA AAAATTAGAA GCCTTGCTTC AGGGTGGTGA AGTGGAAGAG 
GTGATTCTTC AGGCTGAAAA AGAACTAAGT CTGGCAAGGA AAATGTTGAA GTGGAAGCCA 
TGGGAGCCAT TGGTGGAAGA GCCGCCTGCT AACCAGTGGA AGTGGCCAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001297997.1
CDS	140..373
Translation	MAGLLKKTTGLVGLAVCDTPHEEPDVKKLEALLQGGEVEEVILQAEKELSLARKMLKWKPWEPLVEEPPANQWKWPI

Target ORF information:

RefSeq Version	NM_001311068.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001311068.1

ORF Insert Sequence:

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGGAGC CAGATGTTAA AAAATTAGAA GCCTTGCTTC AGGGTGGTGA AGTGGAAGAG 
GTGATTCTTC AGGCTGAAAA AGAACTAAGT CTGGCAAGGA AAATGTTGAA GTGGAAGCCA 
TGGGAGCCAT TGGTGGAAGA GCCGCCTGCT AACCAGTGGA AGTGGCCAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ndufa5 ( NM_001311068.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001297997.1 Mus musculus NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu70235
Clone ID Related Accession (Same CDS sequence)	NM_001311068.1 , NM_001311068.2
Accession Version	NM_001311068.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 234bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC153635.4, BY253904.1, BY247454.1 and W66892.1. On Mar 1, 2018 this sequence version replaced NM_001311068.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BU563501.1, BY247454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGGAGC CAGATGTTAA AAAATTAGAA GCCTTGCTTC AGGGTGGTGA AGTGGAAGAG 
GTGATTCTTC AGGCTGAAAA AGAACTAAGT CTGGCAAGGA AAATGTTGAA GTGGAAGCCA 
TGGGAGCCAT TGGTGGAAGA GCCGCCTGCT AACCAGTGGA AGTGGCCAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001297997.1
CDS	145..378
Translation	MAGLLKKTTGLVGLAVCDTPHEEPDVKKLEALLQGGEVEEVILQAEKELSLARKMLKWKPWEPLVEEPPANQWKWPI

Target ORF information:

RefSeq Version	NM_001311068.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001311068.2

ORF Insert Sequence:

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGGAGC CAGATGTTAA AAAATTAGAA GCCTTGCTTC AGGGTGGTGA AGTGGAAGAG 
GTGATTCTTC AGGCTGAAAA AGAACTAAGT CTGGCAAGGA AAATGTTGAA GTGGAAGCCA 
TGGGAGCCAT TGGTGGAAGA GCCGCCTGCT AACCAGTGGA AGTGGCCAAT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ndufa5 ( NM_026614.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080890.1 Mus musculus NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14757
Clone ID Related Accession (Same CDS sequence)	NM_026614.2 , NM_026614.3
Accession Version	NM_026614.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 351bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-09
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK019301.1. On Apr 5, 2007 this sequence version replaced NM_026614.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK019301.1, BY712440.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGAGGC TCACAATATT GTATACAAAG ACTCTTGATA TTCTGAAGCA CTTTCCTAAA 
CATGCAGCCT ATAGAAAATA CACAGAACAG ATCACCAACG AGAAGCTGGA TATGGTCAAG 
GCGGAGCCAG ATGTTAAAAA ATTAGAAGCC TTGCTTCAGG GTGGTGAAGT GGAAGAGGTG 
ATTCTTCAGG CTGAAAAAGA ACTAAGTCTG GCAAGGAAAA TGTTGAAGTG GAAGCCATGG 
GAGCCATTGG TGGAAGAGCC GCCTGCTAAC CAGTGGAAGT GGCCAATATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080890.1
CDS	142..492
Translation	MAGLLKKTTGLVGLAVCDTPHERLTILYTKTLDILKHFPKHAAYRKYTEQITNEKLDMVKAEPDVKKLEALLQGGEVEEVILQAEKELSLARKMLKWKPWEPLVEEPPANQWKWPI

Target ORF information:

RefSeq Version	NM_026614.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026614.2

ORF Insert Sequence:

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGAGGC TCACAATATT GTATACAAAG ACTCTTGATA TTCTGAAGCA CTTTCCTAAA 
CATGCAGCCT ATAGAAAATA CACAGAACAG ATCACCAACG AGAAGCTGGA TATGGTCAAG 
GCGGAGCCAG ATGTTAAAAA ATTAGAAGCC TTGCTTCAGG GTGGTGAAGT GGAAGAGGTG 
ATTCTTCAGG CTGAAAAAGA ACTAAGTCTG GCAAGGAAAA TGTTGAAGTG GAAGCCATGG 
GAGCCATTGG TGGAAGAGCC GCCTGCTAAC CAGTGGAAGT GGCCAATATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ndufa5 ( NM_026614.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080890.1 Mus musculus NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14757
Clone ID Related Accession (Same CDS sequence)	NM_026614.2 , NM_026614.3
Accession Version	NM_026614.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 351bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY253904.1, AK019301.1 and W66892.1. On Mar 1, 2018 this sequence version replaced NM_026614.2. ##Evidence-Data-START## Transcript exon combination :: BY712440.1, AK019301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGAGGC TCACAATATT GTATACAAAG ACTCTTGATA TTCTGAAGCA CTTTCCTAAA 
CATGCAGCCT ATAGAAAATA CACAGAACAG ATCACCAACG AGAAGCTGGA TATGGTCAAG 
GCGGAGCCAG ATGTTAAAAA ATTAGAAGCC TTGCTTCAGG GTGGTGAAGT GGAAGAGGTG 
ATTCTTCAGG CTGAAAAAGA ACTAAGTCTG GCAAGGAAAA TGTTGAAGTG GAAGCCATGG 
GAGCCATTGG TGGAAGAGCC GCCTGCTAAC CAGTGGAAGT GGCCAATATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080890.1
CDS	145..495
Translation	MAGLLKKTTGLVGLAVCDTPHERLTILYTKTLDILKHFPKHAAYRKYTEQITNEKLDMVKAEPDVKKLEALLQGGEVEEVILQAEKELSLARKMLKWKPWEPLVEEPPANQWKWPI

Target ORF information:

RefSeq Version	NM_026614.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026614.3

ORF Insert Sequence:

ATGGCGGGCT TGCTGAAAAA GACAACTGGC CTGGTGGGGT TGGCGGTGTG CGACACTCCA 
CACGAGAGGC TCACAATATT GTATACAAAG ACTCTTGATA TTCTGAAGCA CTTTCCTAAA 
CATGCAGCCT ATAGAAAATA CACAGAACAG ATCACCAACG AGAAGCTGGA TATGGTCAAG 
GCGGAGCCAG ATGTTAAAAA ATTAGAAGCC TTGCTTCAGG GTGGTGAAGT GGAAGAGGTG 
ATTCTTCAGG CTGAAAAAGA ACTAAGTCTG GCAAGGAAAA TGTTGAAGTG GAAGCCATGG 
GAGCCATTGG TGGAAGAGCC GCCTGCTAAC CAGTGGAAGT GGCCAATATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chronic Activation of ?2 AMPK Induces Obesity and Reduces ? Cell Function.
Cell metabolism23(5)821-36(2016 May)
Yavari A,Stocker CJ,Ghaffari S,Wargent ET,Steeples V,Czibik G,Pinter K,Bellahcene M,Woods A,Mart?nez de Morentin PB,Cansell C,Lam BY,Chuster A,Petkevicius K,Nguyen-Tu MS,Martinez-Sanchez A,Pullen TJ,Oliver PL,Stockenhuber A,Nguyen C,Lazdam M,O'Dowd JF,Harikumar P,T?th M,Beall C,Kyriakou T,Parnis J,Sarma D,Katritsis G,Wortmann DD,Harper AR,Brown LA,Willows R,Gandra S,Poncio V,de Oliveira Figueiredo MJ,Qi NR,Peirson SN,McCrimmon RJ,Gereben B,Tretter L,Fekete C,Redwood C,Yeo GS,Heisler LK,Rutter GA,Smith MA,Withers DJ,Carling D,Sternick EB,Arch JR,Cawthorne MA,Watkins H,Ashrafian H

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Cell metabolism21(4)609-21(2015 Apr)
Dai N,Zhao L,Wrighting D,Kr?mer D,Majithia A,Wang Y,Cracan V,Borges-Rivera D,Mootha VK,Nahrendorf M,Thorburn DR,Minichiello L,Altshuler D,Avruch J

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.
Human molecular genetics23(6)1399-412(2014 Mar)
Peralta S,Torraco A,Wenz T,Garcia S,Diaz F,Moraes CT

Region-specific expression of mitochondrial complex I genes during murine brain development.
PloS one6(4)e18897(2011 Apr)
Wirtz S,Schuelke M

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Ndufa5 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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