BCAS2 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	BCAS2
Entrez Gene ID	68183
Full Name	breast carcinoma amplified sequence 2
Synonyms	6430539P16Rik,AI132645,C76366,C80030
General protein information	Preferred Names breast carcinoma amplified sequence 2 Names pre-mRNA-splicing factor SPF27 DNA amplified in mammary carcinoma 1 protein breast carcinoma-amplified sequence 2 homolog
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 3 Map Location: 3\|3 F2.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001356330.1	NP_001343259.1	pre-mRNA-splicing factor SPF27 isoform 2
NM_001356331.1	NP_001343260.1	pre-mRNA-splicing factor SPF27 isoform 3
XM_006501965.1	XP_006502028.1	pre-mRNA-splicing factor SPF27 isoform X1
NM_026602.4	NP_080878.2	pre-mRNA-splicing factor SPF27 isoform 1
NM_026602.3	NP_080878.2	pre-mRNA-splicing factor SPF27

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Bcas2	NP_001099928.1
Gallus gallus (chicken)	BCAS2	NP_001244224.1
Danio rerio (zebrafish)	bcas2	NP_001007775.1
Arabidopsis thaliana (thale cress)	MOS4	NP_566599.1
Homo sapiens (human)	BCAS2	NP_005863.1
Drosophila melanogaster (fruit fly)	CG4980	NP_651596.1
Xenopus tropicalis (tropical clawed frog)	bcas2	NP_988924.1
Canis lupus familiaris (dog)	BCAS2	XP_533014.1
Bos taurus (cattle)	BCAS2	NP_001015540.1
Mus musculus (house mouse)	Bcas2	NP_080878.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002305	XP_312666.3
Pan troglodytes (chimpanzee)	BCAS2	XP_003308351.1
Caenorhabditis elegans (roundworm)	T12A2.7	NP_498360.2

Gene Ontology
Bibliography

Related articles in PubMed

BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.
Liu W, Wang F, Xu Q, Shi J, Zhang X, Lu X, Zhao ZA, Gao Z, Ma H, Duan E, Gao F, Gao S, Yi Z, Li L
Nature communications814182(2017 Jan)

Conditional Knockout of Breast Carcinoma Amplified Sequence 2 (BCAS2) in Mouse Forebrain Causes Dendritic Malformation via ?-catenin.
Huang CW, Chen YW, Lin YR, Chen PH, Chou MH, Lee LJ, Wang PY, Wu JT, Tsao YP, Chen SL
Scientific reports634927(2016 Oct)

Maternal BCAS2 protects genomic integrity in mouse early embryonic development.
Xu Q, Wang F, Xiang Y, Zhang X, Zhao ZA, Gao Z, Liu W, Lu X, Liu Y, Yu XJ, Wang H, Huang J, Yi Z, Gao S, Li L
Development (Cambridge, England)142(22)3943-53(2015 Nov)

BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
Liao S, Du R, Wang L, Qu Z, Cui X, Li C, Liu F, Huang M, Wang J, Chen J, Gao M, Yu S, Tang Z, Li DW, Jiang T, Liu M
The international journal of biochemistry & cell biology6878-86(2015 Nov)

A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, N?rnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Doll? P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A
PLoS biology9(1)e1000582(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Maternal BCAS2 protects genomic integrity in mouse early embryonic development.
Title: Maternal BCAS2 protects genomic integrity in mouse early embryonic development.

BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
Title: BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.

The following BCAS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BCAS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu32219	NM_001356330.1 Latest version!	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu83862	NM_001356331.1 Latest version!	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu32219	XM_006501965.1 Latest version!	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu02654	NM_026602.4 Latest version!	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu02654	NM_026602.3	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BCAS2 ( NM_001356330.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001343259.1 Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu32219
Clone ID Related Accession (Same CDS sequence)	NM_001356330.1 , XM_006501965.1
Accession Version	NM_001356330.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	pre-mRNA-splicing factor SPF27 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC150894.4. On Sep 29, 2017 this sequence version replaced XM_006501965.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BG921072.1, BI653022.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAG 
AAACATATTC AAGATTTGAA CTGGCAGCGA AAGAACATGC AGCTTACAGC TGGATCTAAG 
CTGAGAGAAA TGGAGTCAAA CTGGGTGTCG CTGGTGAGTA AGAACTATGA GATTGAGCGG 
ACGATTGTCC AGCTGGAGAA CGAGATCTAT CAGATCAAGC AGCAGCACGG GGAGGCCAAC 
AAGGAAAACA TCCGCCAAGA CTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001343259.1
CDS	119..745
Translation	MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNEKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Target ORF information:

RefSeq Version	NM_001356330.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001356330.1

ORF Insert Sequence:

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAG 
AAACATATTC AAGATTTGAA CTGGCAGCGA AAGAACATGC AGCTTACAGC TGGATCTAAG 
CTGAGAGAAA TGGAGTCAAA CTGGGTGTCG CTGGTGAGTA AGAACTATGA GATTGAGCGG 
ACGATTGTCC AGCTGGAGAA CGAGATCTAT CAGATCAAGC AGCAGCACGG GGAGGCCAAC 
AAGGAAAACA TCCGCCAAGA CTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCAS2 ( NM_001356331.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001343260.1 Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu83862
Clone ID Related Accession (Same CDS sequence)	NM_001356331.1
Accession Version	NM_001356331.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	pre-mRNA-splicing factor SPF27 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC150894.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC023382.1, BI249654.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAAATG AATTTGAAAG ACTCGCTGCT CGACAACCGA TTGAATTACT CAGCATGAAA 
CGATATGAAC TTCCAGCCCC TTCCTCAGGT CAAAAAAATG ACATTACTGC ATGGCAAGAA 
TGTGTAAACA ATTCTATGGC TCAGTTGGAG CACCAGGCGG TCCGGATCGA GAATCTGGAG 
CTGATGTCAC AGCATGGATG CAATGCCTGG AAGGTGTACA ATGAAAATCT TGTTCATATG 
ATTGAACATG CACAGAAAGA GCTTCAGAAG TTAAGGAAAC ATATTCAAGA TTTGAACTGG 
CAGCGAAAGA ACATGCAGCT TACAGCTGGA TCTAAGCTGA GAGAAATGGA GTCAAACTGG 
GTGTCGCTGG TGAGTAAGAA CTATGAGATT GAGCGGACGA TTGTCCAGCT GGAGAACGAG 
ATCTATCAGA TCAAGCAGCA GCACGGGGAG GCCAACAAGG AAAACATCCG CCAAGACTTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001343260.1
CDS	355..837
Translation	MRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Target ORF information:

RefSeq Version	NM_001356331.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001356331.1

ORF Insert Sequence:

ATGAGAAATG AATTTGAAAG ACTCGCTGCT CGACAACCGA TTGAATTACT CAGCATGAAA 
CGATATGAAC TTCCAGCCCC TTCCTCAGGT CAAAAAAATG ACATTACTGC ATGGCAAGAA 
TGTGTAAACA ATTCTATGGC TCAGTTGGAG CACCAGGCGG TCCGGATCGA GAATCTGGAG 
CTGATGTCAC AGCATGGATG CAATGCCTGG AAGGTGTACA ATGAAAATCT TGTTCATATG 
ATTGAACATG CACAGAAAGA GCTTCAGAAG TTAAGGAAAC ATATTCAAGA TTTGAACTGG 
CAGCGAAAGA ACATGCAGCT TACAGCTGGA TCTAAGCTGA GAGAAATGGA GTCAAACTGG 
GTGTCGCTGG TGAGTAAGAA CTATGAGATT GAGCGGACGA TTGTCCAGCT GGAGAACGAG 
ATCTATCAGA TCAAGCAGCA GCACGGGGAG GCCAACAAGG AAAACATCCG CCAAGACTTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCAS2 ( XM_006501965.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006502028.1 Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu32219
Clone ID Related Accession (Same CDS sequence)	NM_001356330.1 , XM_006501965.1
Accession Version	XM_006501965.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	pre-mRNA-splicing factor SPF27 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000069.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAG 
AAACATATTC AAGATTTGAA CTGGCAGCGA AAGAACATGC AGCTTACAGC TGGATCTAAG 
CTGAGAGAAA TGGAGTCAAA CTGGGTGTCG CTGGTGAGTA AGAACTATGA GATTGAGCGG 
ACGATTGTCC AGCTGGAGAA CGAGATCTAT CAGATCAAGC AGCAGCACGG GGAGGCCAAC 
AAGGAAAACA TCCGCCAAGA CTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006502028.1
CDS	114..740
Translation	MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNEKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Target ORF information:

RefSeq Version	XM_006501965.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006501965.1

ORF Insert Sequence:

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAG 
AAACATATTC AAGATTTGAA CTGGCAGCGA AAGAACATGC AGCTTACAGC TGGATCTAAG 
CTGAGAGAAA TGGAGTCAAA CTGGGTGTCG CTGGTGAGTA AGAACTATGA GATTGAGCGG 
ACGATTGTCC AGCTGGAGAA CGAGATCTAT CAGATCAAGC AGCAGCACGG GGAGGCCAAC 
AAGGAAAACA TCCGCCAAGA CTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCAS2 ( NM_026602.4 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_080878.2 Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu02654
Clone ID Related Accession (Same CDS sequence)	NM_026602.4 , NM_026602.3
Accession Version	NM_026602.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	pre-mRNA-splicing factor SPF27 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC150894.4. On Sep 29, 2017 this sequence version replaced NM_026602.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK153513.1, SRR1660815.310677.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAA 
AATCTTGTTC ATATGATTGA ACATGCACAG AAAGAGCTTC AGAAGTTAAG GAAACATATT 
CAAGATTTGA ACTGGCAGCG AAAGAACATG CAGCTTACAG CTGGATCTAA GCTGAGAGAA 
ATGGAGTCAA ACTGGGTGTC GCTGGTGAGT AAGAACTATG AGATTGAGCG GACGATTGTC 
CAGCTGGAGA ACGAGATCTA TCAGATCAAG CAGCAGCACG GGGAGGCCAA CAAGGAAAAC 
ATCCGCCAAG ACTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080878.2
CDS	119..796
Translation	MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Target ORF information:

RefSeq Version	NM_026602.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026602.4

ORF Insert Sequence:

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAA 
AATCTTGTTC ATATGATTGA ACATGCACAG AAAGAGCTTC AGAAGTTAAG GAAACATATT 
CAAGATTTGA ACTGGCAGCG AAAGAACATG CAGCTTACAG CTGGATCTAA GCTGAGAGAA 
ATGGAGTCAA ACTGGGTGTC GCTGGTGAGT AAGAACTATG AGATTGAGCG GACGATTGTC 
CAGCTGGAGA ACGAGATCTA TCAGATCAAG CAGCAGCACG GGGAGGCCAA CAAGGAAAAC 
ATCCGCCAAG ACTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCAS2 ( NM_026602.3 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_080878.2 Mus musculus breast carcinoma amplified sequence 2 (Bcas2), mRNA.

Price & Availability↑

CloneID	OMu02654
Clone ID Related Accession (Same CDS sequence)	NM_026602.4 , NM_026602.3
Accession Version	NM_026602.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-27
Organism	Mus musculus(House mouse)
Product	pre-mRNA-splicing factor SPF27
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC150894.4. On Oct 26, 2006 this sequence version replaced NM_026602.2. Sequence Note: This RefSeq record was created using sequence from the reference genome strain C57BL/6J because transcripts from the reference strain were not available for the full length of the gene. ##Evidence-Data-START## Transcript exon combination :: AK153513.1, SRR1660815.310677.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAA 
AATCTTGTTC ATATGATTGA ACATGCACAG AAAGAGCTTC AGAAGTTAAG GAAACATATT 
CAAGATTTGA ACTGGCAGCG AAAGAACATG CAGCTTACAG CTGGATCTAA GCTGAGAGAA 
ATGGAGTCAA ACTGGGTGTC GCTGGTGAGT AAGAACTATG AGATTGAGCG GACGATTGTC 
CAGCTGGAGA ACGAGATCTA TCAGATCAAG CAGCAGCACG GGGAGGCCAA CAAGGAAAAC 
ATCCGCCAAG ACTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080878.2
CDS	63..740
Translation	MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Target ORF information:

RefSeq Version	NM_026602.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus breast carcinoma amplified sequence 2 (Bcas2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026602.3

ORF Insert Sequence:

ATGGCGGGCA CGGGCTTGGT AGCCGGAGAG GTGGTGGTAG ATGCGCTACC ATATTTTGAC 
CAAGGCTATG AGGCACCCGG CGTGCGGGAA GCGGCGGCGG CCCTGGTGGA GGAGGAGACG 
CGCAGATACC GACCTACCAA GAACTACCTG AGCTACCTGA CGGCCCCGGA TTATTCTGCC 
TTTGAAACAG ACATAATGAG AAATGAATTT GAAAGACTCG CTGCTCGACA ACCGATTGAA 
TTACTCAGCA TGAAACGATA TGAACTTCCA GCCCCTTCCT CAGGTCAAAA AAATGACATT 
ACTGCATGGC AAGAATGTGT AAACAATTCT ATGGCTCAGT TGGAGCACCA GGCGGTCCGG 
ATCGAGAATC TGGAGCTGAT GTCACAGCAT GGATGCAATG CCTGGAAGGT GTACAATGAA 
AATCTTGTTC ATATGATTGA ACATGCACAG AAAGAGCTTC AGAAGTTAAG GAAACATATT 
CAAGATTTGA ACTGGCAGCG AAAGAACATG CAGCTTACAG CTGGATCTAA GCTGAGAGAA 
ATGGAGTCAA ACTGGGTGTC GCTGGTGAGT AAGAACTATG AGATTGAGCG GACGATTGTC 
CAGCTGGAGA ACGAGATCTA TCAGATCAAG CAGCAGCACG GGGAGGCCAA CAAGGAAAAC 
ATCCGCCAAG ACTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.
Nature communications814182(2017 Jan)
Liu W,Wang F,Xu Q,Shi J,Zhang X,Lu X,Zhao ZA,Gao Z,Ma H,Duan E,Gao F,Gao S,Yi Z,Li L

Conditional Knockout of Breast Carcinoma Amplified Sequence 2 (BCAS2) in Mouse Forebrain Causes Dendritic Malformation via ?-catenin.
Scientific reports634927(2016 Oct)
Huang CW,Chen YW,Lin YR,Chen PH,Chou MH,Lee LJ,Wang PY,Wu JT,Tsao YP,Chen SL

Maternal BCAS2 protects genomic integrity in mouse early embryonic development.
Development (Cambridge, England)142(22)3943-53(2015 Nov)
Xu Q,Wang F,Xiang Y,Zhang X,Zhao ZA,Gao Z,Liu W,Lu X,Liu Y,Yu XJ,Wang H,Huang J,Yi Z,Gao S,Li L

BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
The international journal of biochemistry & cell biology6878-86(2015 Nov)
Liao S,Du R,Wang L,Qu Z,Cui X,Li C,Liu F,Huang M,Wang J,Chen J,Gao M,Yu S,Tang Z,Li DW,Jiang T,Liu M

A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
PLoS biology9(1)e1000582(2011 Jan)
Diez-Roux G,Banfi S,Sultan M,Geffers L,Anand S,Rozado D,Magen A,Canidio E,Pagani M,Peluso I,Lin-Marq N,Koch M,Bilio M,Cantiello I,Verde R,De Masi C,Bianchi SA,Cicchini J,Perroud E,Mehmeti S,Dagand E,Schrinner S,N?rnberger A,Schmidt K,Metz K,Zwingmann C,Brieske N,Springer C,Hernandez AM,Herzog S,Grabbe F,Sieverding C,Fischer B,Schrader K,Brockmeyer M,Dettmer S,Helbig C,Alunni V,Battaini MA,Mura C,Henrichsen CN,Garcia-Lopez R,Echevarria D,Puelles E,Garcia-Calero E,Kruse S,Uhr M,Kauck C,Feng G,Milyaev N,Ong CK,Kumar L,Lam M,Semple CA,Gyenesei A,Mundlos S,Radelof U,Lehrach H,Sarmientos P,Reymond A,Davidson DR,Doll? P,Antonarakis SE,Yaspo ML,Martinez S,Baldock RA,Eichele G,Ballabio A

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BCAS2 cDNA ORF clone, Mus musculus(House mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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