Rpl22l1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rpl22l1
Entrez Gene ID	68028
Full Name	ribosomal protein L22 like 1
Synonyms	3110001N18Rik,AU041196
General protein information	Preferred Names ribosomal protein L22 like 1 Names 60S ribosomal protein L22-like 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 A3

mRNA and Protein(s)

mRNA	Protein	Name
NM_026517.2	NP_080793.1	60S ribosomal protein L22-like 1 isoform 1
NM_026517.3	NP_080793.1	60S ribosomal protein L22-like 1 isoform 1
NM_001347226.2	NP_001334155.1	60S ribosomal protein L22-like 1 isoform 2
NM_001347226.1	NP_001334155.1	60S ribosomal protein L22-like 1 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RPL22L1	NP_001091600.1
Bos taurus (cattle)	LOC100294785	XP_002699371.1
Rattus norvegicus (Norway rat)	Rpl22l1	NP_001102018.1
Danio rerio (zebrafish)	rpl22l1	NP_001038800.1
Mus musculus (house mouse)	Rpl22l1	NP_080793.1
Gallus gallus (chicken)	RPL22L1	NP_001264646.1

Gene Ontology
Bibliography

Related articles in PubMed

Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.
Zhang Y, O'Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL
Cell reports18(2)545-556(2017 01)

Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition.
Wu N, Wei J, Wang Y, Yan J, Qin Y, Tong D, Pang B, Sun D, Sun H, Yu Y, Sun W, Meng X, Zhang C, Bai J, Chen F, Geng J, Lee KY, Fu S, Jin Y
PloS one10(11)e0143659(2015)

The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.
O'Leary MN, Schreiber KH, Zhang Y, Duc AC, Rao S, Hale JS, Academia EC, Shah SR, Morton JF, Holstein CA, Martin DB, Kaeberlein M, Ladiges WC, Fink PJ, Mackay VL, Wiest DL, Kennedy BK
PLoS genetics9(8)e1003708(2013)

Phosphoproteomic analysis of the developing mouse brain.
Ballif BA, Vill?n J, Beausoleil SA, Schwartz D, Gygi SP
Molecular & cellular proteomics : MCP3(11)1093-101(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rpl22, and its highly homologous paralog Rpl22-Like1 (Rpl22l1 or Like1) play critical, extraribosomal roles in embryogenesis.
Title: Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.

RPL22L1 induces epithelial-to-mesenchymal transition and is critical in maintaining the aggressive phenotype of ovarian cancer.
Title: Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition.

either ribosomal protein can support translation, knockdown of Rpl22l1 impairs growth of cells lacking Rpl22. Mechanistically, Rpl22 regulates Rpl22l1 directly by binding to an internal hairpin structure and repressing its expression
Title: The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.

The following Rpl22l1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rpl22l1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu31419	NM_001347226.2 Latest version!	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu14899	NM_026517.3 Latest version!	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu14899	NM_026517.2	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu31419	NM_001347226.1	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rpl22l1 ( NM_001347226.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334155.1 Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu31419
Clone ID Related Accession (Same CDS sequence)	NM_001347226.2 , NM_001347226.1
Accession Version	NM_001347226.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L22-like 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY196728.1, AK013966.1 and AC122490.3. On Mar 28, 2018 this sequence version replaced NM_001347226.1. ##Evidence-Data-START## Transcript exon combination :: CN834075.1, CN835045.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGA AAGACAAGAA GCCTAAGAAG TCCACCTGGA GGTTTCATTT GGACCTTACT 
CATCCAGTAG AAGATGGAAT TTTTGACTCT GGAAATTTTG AACAGTTTCT ACGGGAGAAG 
GTTAAAGTCA ATGGAAAAAC TGGAAATCTT GGCAATGTTG TTCACATTGA ACGCCTGAAG 
AATAAAATCA CAGTTGTTTC TGAGAAACAG TTCTCCAAAA GGTATTTGAA ATATCTTACC 
AAGAAATACC TTAAGAAGAA TAATCTCCGT GATTGGCTAC GTGTGGTCGC ATCTGACAAG 
GAGACTTACG AACTTCGTTA TTTCCAGATT AGTCAAGATG AAGATGGTTC AGAGTCTGAG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334155.1
CDS	28..393
Translation	MAPKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED

Target ORF information:

RefSeq Version	NM_001347226.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347226.2

ORF Insert Sequence:

ATGGCGCCGA AAGACAAGAA GCCTAAGAAG TCCACCTGGA GGTTTCATTT GGACCTTACT 
CATCCAGTAG AAGATGGAAT TTTTGACTCT GGAAATTTTG AACAGTTTCT ACGGGAGAAG 
GTTAAAGTCA ATGGAAAAAC TGGAAATCTT GGCAATGTTG TTCACATTGA ACGCCTGAAG 
AATAAAATCA CAGTTGTTTC TGAGAAACAG TTCTCCAAAA GGTATTTGAA ATATCTTACC 
AAGAAATACC TTAAGAAGAA TAATCTCCGT GATTGGCTAC GTGTGGTCGC ATCTGACAAG 
GAGACTTACG AACTTCGTTA TTTCCAGATT AGTCAAGATG AAGATGGTTC AGAGTCTGAG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rpl22l1 ( NM_001347226.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334155.1 Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu31419
Clone ID Related Accession (Same CDS sequence)	NM_001347226.2 , NM_001347226.1
Accession Version	NM_001347226.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L22-like 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK013966.1 and AC122490.3. On Nov 18, 2016 this sequence version replaced XM_006535531.2. ##Evidence-Data-START## Transcript exon combination :: CN834075.1, CD769670.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCCGA AAGACAAGAA GCCTAAGAAG TCCACCTGGA GGTTTCATTT GGACCTTACT 
CATCCAGTAG AAGATGGAAT TTTTGACTCT GGAAATTTTG AACAGTTTCT ACGGGAGAAG 
GTTAAAGTCA ATGGAAAAAC TGGAAATCTT GGCAATGTTG TTCACATTGA ACGCCTGAAG 
AATAAAATCA CAGTTGTTTC TGAGAAACAG TTCTCCAAAA GGTATTTGAA ATATCTTACC 
AAGAAATACC TTAAGAAGAA TAATCTCCGT GATTGGCTAC GTGTGGTCGC ATCTGACAAG 
GAGACTTACG AACTTCGTTA TTTCCAGATT AGTCAAGATG AAGATGGTTC AGAGTCTGAG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334155.1
CDS	25..390
Translation	MAPKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED

Target ORF information:

RefSeq Version	NM_001347226.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347226.1

ORF Insert Sequence:

ATGGCGCCGA AAGACAAGAA GCCTAAGAAG TCCACCTGGA GGTTTCATTT GGACCTTACT 
CATCCAGTAG AAGATGGAAT TTTTGACTCT GGAAATTTTG AACAGTTTCT ACGGGAGAAG 
GTTAAAGTCA ATGGAAAAAC TGGAAATCTT GGCAATGTTG TTCACATTGA ACGCCTGAAG 
AATAAAATCA CAGTTGTTTC TGAGAAACAG TTCTCCAAAA GGTATTTGAA ATATCTTACC 
AAGAAATACC TTAAGAAGAA TAATCTCCGT GATTGGCTAC GTGTGGTCGC ATCTGACAAG 
GAGACTTACG AACTTCGTTA TTTCCAGATT AGTCAAGATG AAGATGGTTC AGAGTCTGAG 
GACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rpl22l1 ( NM_026517.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080793.1 Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14899
Clone ID Related Accession (Same CDS sequence)	NM_026517.2 , NM_026517.3
Accession Version	NM_026517.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L22-like 1 isoform 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK008915.1. On Apr 6, 2007 this sequence version replaced NM_026517.1. ##Evidence-Data-START## Transcript exon combination :: AK008915.1, CB570612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCCGC AGAAAGACAA GAAGCCTAAG AAGTCCACCT GGAGGTTTCA TTTGGACCTT 
ACTCATCCAG TAGAAGATGG AATTTTTGAC TCTGGAAATT TTGAACAGTT TCTACGGGAG 
AAGGTTAAAG TCAATGGAAA AACTGGAAAT CTTGGCAATG TTGTTCACAT TGAACGCCTG 
AAGAATAAAA TCACAGTTGT TTCTGAGAAA CAGTTCTCCA AAAGGTATTT GAAATATCTT 
ACCAAGAAAT ACCTTAAGAA GAATAATCTC CGTGATTGGC TACGTGTGGT CGCATCTGAC 
AAGGAGACTT ACGAACTTCG TTATTTCCAG ATTAGTCAAG ATGAAGATGG TTCAGAGTCT 
GAGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080793.1
CDS	25..393
Translation	MAPQKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED

Target ORF information:

RefSeq Version	NM_026517.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026517.2

ORF Insert Sequence:

ATGGCGCCGC AGAAAGACAA GAAGCCTAAG AAGTCCACCT GGAGGTTTCA TTTGGACCTT 
ACTCATCCAG TAGAAGATGG AATTTTTGAC TCTGGAAATT TTGAACAGTT TCTACGGGAG 
AAGGTTAAAG TCAATGGAAA AACTGGAAAT CTTGGCAATG TTGTTCACAT TGAACGCCTG 
AAGAATAAAA TCACAGTTGT TTCTGAGAAA CAGTTCTCCA AAAGGTATTT GAAATATCTT 
ACCAAGAAAT ACCTTAAGAA GAATAATCTC CGTGATTGGC TACGTGTGGT CGCATCTGAC 
AAGGAGACTT ACGAACTTCG TTATTTCCAG ATTAGTCAAG ATGAAGATGG TTCAGAGTCT 
GAGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rpl22l1 ( NM_026517.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080793.1 Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu14899
Clone ID Related Accession (Same CDS sequence)	NM_026517.2 , NM_026517.3
Accession Version	NM_026517.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Mus musculus(house mouse)
Product	60S ribosomal protein L22-like 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY196728.1, AK008915.1 and AC122490.3. On Mar 19, 2018 this sequence version replaced NM_026517.2. ##Evidence-Data-START## Transcript exon combination :: CB317228.1, BU530579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGC AGAAAGACAA GAAGCCTAAG AAGTCCACCT GGAGGTTTCA TTTGGACCTT 
ACTCATCCAG TAGAAGATGG AATTTTTGAC TCTGGAAATT TTGAACAGTT TCTACGGGAG 
AAGGTTAAAG TCAATGGAAA AACTGGAAAT CTTGGCAATG TTGTTCACAT TGAACGCCTG 
AAGAATAAAA TCACAGTTGT TTCTGAGAAA CAGTTCTCCA AAAGGTATTT GAAATATCTT 
ACCAAGAAAT ACCTTAAGAA GAATAATCTC CGTGATTGGC TACGTGTGGT CGCATCTGAC 
AAGGAGACTT ACGAACTTCG TTATTTCCAG ATTAGTCAAG ATGAAGATGG TTCAGAGTCT 
GAGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080793.1
CDS	28..396
Translation	MAPQKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED

Target ORF information:

RefSeq Version	NM_026517.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribosomal protein L22 like 1 (Rpl22l1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026517.3

ORF Insert Sequence:

ATGGCGCCGC AGAAAGACAA GAAGCCTAAG AAGTCCACCT GGAGGTTTCA TTTGGACCTT 
ACTCATCCAG TAGAAGATGG AATTTTTGAC TCTGGAAATT TTGAACAGTT TCTACGGGAG 
AAGGTTAAAG TCAATGGAAA AACTGGAAAT CTTGGCAATG TTGTTCACAT TGAACGCCTG 
AAGAATAAAA TCACAGTTGT TTCTGAGAAA CAGTTCTCCA AAAGGTATTT GAAATATCTT 
ACCAAGAAAT ACCTTAAGAA GAATAATCTC CGTGATTGGC TACGTGTGGT CGCATCTGAC 
AAGGAGACTT ACGAACTTCG TTATTTCCAG ATTAGTCAAG ATGAAGATGG TTCAGAGTCT 
GAGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.
Cell reports18(2)545-556(2017 01)
Zhang Y,O'Leary MN,Peri S,Wang M,Zha J,Melov S,Kappes DJ,Feng Q,Rhodes J,Amieux PS,Morris DR,Kennedy BK,Wiest DL

Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition.
PloS one10(11)e0143659(2015)
Wu N,Wei J,Wang Y,Yan J,Qin Y,Tong D,Pang B,Sun D,Sun H,Yu Y,Sun W,Meng X,Zhang C,Bai J,Chen F,Geng J,Lee KY,Fu S,Jin Y

The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.
PLoS genetics9(8)e1003708(2013)
O'Leary MN,Schreiber KH,Zhang Y,Duc AC,Rao S,Hale JS,Academia EC,Shah SR,Morton JF,Holstein CA,Martin DB,Kaeberlein M,Ladiges WC,Fink PJ,Mackay VL,Wiest DL,Kennedy BK

Phosphoproteomic analysis of the developing mouse brain.
Molecular & cellular proteomics : MCP3(11)1093-101(2004 Nov)
Ballif BA,Vill?n J,Beausoleil SA,Schwartz D,Gygi SP

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Rpl22l1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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