Decr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Decr1
Entrez Gene ID	67460
Full Name	2,4-dienoyl CoA reductase 1, mitochondrial
Synonyms	1200012F07Rik,Decr,Nadph
General protein information	Preferred Names 2,4-dienoyl CoA reductase 1, mitochondrial Names 2,4-dienoyl-CoA reductase, mitochondrial 4-enoyl-CoA reductase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 A2

mRNA and Protein(s)

mRNA	Protein	Name
NM_026172.4	NP_080448.1	2,4-dienoyl-CoA reductase, mitochondrial precursor
NM_026172.3	NP_080448.1	2,4-dienoyl-CoA reductase, mitochondrial precursor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	decr1	NP_001002444.2
Gallus gallus (chicken)	DECR1	XP_418328.1
Xenopus tropicalis (tropical clawed frog)	decr1	NP_001076813.1
Pan troglodytes (chimpanzee)	DECR1	XP_001138969.1
Canis lupus familiaris (dog)	DECR1	XP_535127.4
Homo sapiens (human)	DECR1	NP_001350.1
Bos taurus (cattle)	DECR1	NP_001068891.1
Mus musculus (house mouse)	Decr1	NP_080448.1
	DECR1	XP_001085155.1
Rattus norvegicus (Norway rat)	Decr1	NP_476545.2

Gene Ontology
Bibliography

Related articles in PubMed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
Zhou L, Dai H, Wu J, Zhou M, Yuan H, Du J, Yang L, Wu X, Xu H, Hua Y, Xu J, Zheng L, Shen B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(1)132-147(2017 01)

Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
Boyle MP, Bernard A, Thompson CL, Ng L, Boe A, Mortrud M, Hawrylycz MJ, Jones AR, Hevner RF, Lein ES
The Journal of comparative neurology519(11)2061-89(2011 Aug)

Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
Miinalainen IJ, Schmitz W, Huotari A, Autio KJ, Soininen R, Ver Loren van Themaat E, Baes M, Herzig KH, Conzelmann E, Hiltunen JK
PLoS genetics5(7)e1000543(2009 Jul)

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y
Molecular cell23(4)607-18(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Fasted Decr(-/-) mice displayed increased serum acylcarnitines and unimpaired ketogenesis.
Title: Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.

The following Decr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Decr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14704	NM_026172.4 Latest version!	Mus musculus 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu14704	NM_026172.3	Mus musculus 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Decr1 ( NM_026172.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080448.1 Mus musculus 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), mRNA.

Price & Availability↑

CloneID	OMu14704
Clone ID Related Accession (Same CDS sequence)	NM_026172.4 , NM_026172.3
Accession Version	NM_026172.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	2,4-dienoyl-CoA reductase, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC046972.1. On May 4, 2018 this sequence version replaced NM_026172.3. ##Evidence-Data-START## Transcript exon combination :: BC046972.1, AK146003.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCTGC TGGGCCGTGC GTTCTTTGCT GGGGTGTCCC GCCTCCCCTG CGATCCGGGT 
CCTCAGAGGT TTTTCAGCTT TGGAACAAAA ACACTGTATC AAAGCAAAGA TGCTCCACAG 
TCTAAATTCT TCCAGCCCGT TTTAAAGCCT ATGCTACCAC CTGATGCTTT TCAAGGAAAA 
GTGGCTTTCA TTACTGGAGG AGGGACTGGC CTTGGCAAGG CAATGACAAC TTTCTTGTCT 
ACCCTGGGTG CCCAGTGTGT GATAGCCAGC AGAAATATTG ATGTTTTGAA AGCGACTGCA 
GAAGAGATTT CTTCTAAAAC TGGAAACAAG GTTCATGCGA TTCGGTGTGA TGTTCGAGAT 
CCTGATATGG TACATAACAC AGTGCTGGAA CTGATCAAAG TTGCAGGGCA TCCGGATGTG 
GTGATAAACA ACGCGGCAGG GAACTTCATT TCCCCCAGTG AGAGACTGAC TCCCAATGGC 
TGGAAGACCA TAACTGACAT AGTTCTCAAT GGCACAGCCT ATGTGACACT AGAAATTGGA 
AAGCAGCTAA TTAAAGCACA GAAAGGAGCT GCGTTTCTTG CCATCACTAC CATCTATGCT 
GAGAGTGGAT CAGGCTTTGT AATGCCAAGT TCTTCAGCCA AATCAGGCGT GGAAGCCATG 
AATAAGTCAC TTGCAGCTGA ATGGGGTAGA TATGGAATGC GTTTCAACAT AATTCAGCCA 
GGACCTATCA AAACCAAAGG AGCCTTTAGC CGTTTGGACC CGACTGGAAG ATTTGAGAAG 
GAGATGATTG ACAGAATCCC CTGTGGTCGT CTGGGAACTA TGGAGGAACT TGCAAATCTG 
GCCACTTTCC TATGCAGTGA TTATGCCTCT TGGATTAATG GAGCAGTCAT TAGATTTGAC 
GGTGGAGAGG AAGTATTTCT GTCAGGTGAA TTCAACTCTC TAAAGAAGGT CACCAAGGAG 
GAGTGGGATA TAATCGAAGG GCTCATCAGG AAGACAAAAG GCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080448.1
CDS	27..1034
Translation	MALLGRAFFAGVSRLPCDPGPQRFFSFGTKTLYQSKDAPQSKFFQPVLKPMLPPDAFQGKVAFITGGGTGLGKAMTTFLSTLGAQCVIASRNIDVLKATAEEISSKTGNKVHAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLTPNGWKTITDIVLNGTAYVTLEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGRFEKEMIDRIPCGRLGTMEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDIIEGLIRKTKGS

Target ORF information:

RefSeq Version	NM_026172.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026172.4

ORF Insert Sequence:

ATGGCGCTGC TGGGCCGTGC GTTCTTTGCT GGGGTGTCCC GCCTCCCCTG CGATCCGGGT 
CCTCAGAGGT TTTTCAGCTT TGGAACAAAA ACACTGTATC AAAGCAAAGA TGCTCCACAG 
TCTAAATTCT TCCAGCCCGT TTTAAAGCCT ATGCTACCAC CTGATGCTTT TCAAGGAAAA 
GTGGCTTTCA TTACTGGAGG AGGGACTGGC CTTGGCAAGG CAATGACAAC TTTCTTGTCT 
ACCCTGGGTG CCCAGTGTGT GATAGCCAGC AGAAATATTG ATGTTTTGAA AGCGACTGCA 
GAAGAGATTT CTTCTAAAAC TGGAAACAAG GTTCATGCGA TTCGGTGTGA TGTTCGAGAT 
CCTGATATGG TACATAACAC AGTGCTGGAA CTGATCAAAG TTGCAGGGCA TCCGGATGTG 
GTGATAAACA ACGCGGCAGG GAACTTCATT TCCCCCAGTG AGAGACTGAC TCCCAATGGC 
TGGAAGACCA TAACTGACAT AGTTCTCAAT GGCACAGCCT ATGTGACACT AGAAATTGGA 
AAGCAGCTAA TTAAAGCACA GAAAGGAGCT GCGTTTCTTG CCATCACTAC CATCTATGCT 
GAGAGTGGAT CAGGCTTTGT AATGCCAAGT TCTTCAGCCA AATCAGGCGT GGAAGCCATG 
AATAAGTCAC TTGCAGCTGA ATGGGGTAGA TATGGAATGC GTTTCAACAT AATTCAGCCA 
GGACCTATCA AAACCAAAGG AGCCTTTAGC CGTTTGGACC CGACTGGAAG ATTTGAGAAG 
GAGATGATTG ACAGAATCCC CTGTGGTCGT CTGGGAACTA TGGAGGAACT TGCAAATCTG 
GCCACTTTCC TATGCAGTGA TTATGCCTCT TGGATTAATG GAGCAGTCAT TAGATTTGAC 
GGTGGAGAGG AAGTATTTCT GTCAGGTGAA TTCAACTCTC TAAAGAAGGT CACCAAGGAG 
GAGTGGGATA TAATCGAAGG GCTCATCAGG AAGACAAAAG GCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Decr1 ( NM_026172.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080448.1 Mus musculus 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), mRNA.

Price & Availability↑

CloneID	OMu14704
Clone ID Related Accession (Same CDS sequence)	NM_026172.4 , NM_026172.3
Accession Version	NM_026172.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-28
Organism	Mus musculus(house mouse)
Product	2,4-dienoyl-CoA reductase, mitochondrial precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC046972.1. On Jun 19, 2003 this sequence version replaced NM_026172.2. ##Evidence-Data-START## Transcript exon combination :: BC046972.1, AK146003.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCGCTGC TGGGCCGTGC GTTCTTTGCT GGGGTGTCCC GCCTCCCCTG CGATCCGGGT 
CCTCAGAGGT TTTTCAGCTT TGGAACAAAA ACACTGTATC AAAGCAAAGA TGCTCCACAG 
TCTAAATTCT TCCAGCCCGT TTTAAAGCCT ATGCTACCAC CTGATGCTTT TCAAGGAAAA 
GTGGCTTTCA TTACTGGAGG AGGGACTGGC CTTGGCAAGG CAATGACAAC TTTCTTGTCT 
ACCCTGGGTG CCCAGTGTGT GATAGCCAGC AGAAATATTG ATGTTTTGAA AGCGACTGCA 
GAAGAGATTT CTTCTAAAAC TGGAAACAAG GTTCATGCGA TTCGGTGTGA TGTTCGAGAT 
CCTGATATGG TACATAACAC AGTGCTGGAA CTGATCAAAG TTGCAGGGCA TCCGGATGTG 
GTGATAAACA ACGCGGCAGG GAACTTCATT TCCCCCAGTG AGAGACTGAC TCCCAATGGC 
TGGAAGACCA TAACTGACAT AGTTCTCAAT GGCACAGCCT ATGTGACACT AGAAATTGGA 
AAGCAGCTAA TTAAAGCACA GAAAGGAGCT GCGTTTCTTG CCATCACTAC CATCTATGCT 
GAGAGTGGAT CAGGCTTTGT AATGCCAAGT TCTTCAGCCA AATCAGGCGT GGAAGCCATG 
AATAAGTCAC TTGCAGCTGA ATGGGGTAGA TATGGAATGC GTTTCAACAT AATTCAGCCA 
GGACCTATCA AAACCAAAGG AGCCTTTAGC CGTTTGGACC CGACTGGAAG ATTTGAGAAG 
GAGATGATTG ACAGAATCCC CTGTGGTCGT CTGGGAACTA TGGAGGAACT TGCAAATCTG 
GCCACTTTCC TATGCAGTGA TTATGCCTCT TGGATTAATG GAGCAGTCAT TAGATTTGAC 
GGTGGAGAGG AAGTATTTCT GTCAGGTGAA TTCAACTCTC TAAAGAAGGT CACCAAGGAG 
GAGTGGGATA TAATCGAAGG GCTCATCAGG AAGACAAAAG GCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080448.1
CDS	157..1164
Translation	MALLGRAFFAGVSRLPCDPGPQRFFSFGTKTLYQSKDAPQSKFFQPVLKPMLPPDAFQGKVAFITGGGTGLGKAMTTFLSTLGAQCVIASRNIDVLKATAEEISSKTGNKVHAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLTPNGWKTITDIVLNGTAYVTLEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGRFEKEMIDRIPCGRLGTMEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDIIEGLIRKTKGS

Target ORF information:

RefSeq Version	NM_026172.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026172.3

ORF Insert Sequence:

ATGGCGCTGC TGGGCCGTGC GTTCTTTGCT GGGGTGTCCC GCCTCCCCTG CGATCCGGGT 
CCTCAGAGGT TTTTCAGCTT TGGAACAAAA ACACTGTATC AAAGCAAAGA TGCTCCACAG 
TCTAAATTCT TCCAGCCCGT TTTAAAGCCT ATGCTACCAC CTGATGCTTT TCAAGGAAAA 
GTGGCTTTCA TTACTGGAGG AGGGACTGGC CTTGGCAAGG CAATGACAAC TTTCTTGTCT 
ACCCTGGGTG CCCAGTGTGT GATAGCCAGC AGAAATATTG ATGTTTTGAA AGCGACTGCA 
GAAGAGATTT CTTCTAAAAC TGGAAACAAG GTTCATGCGA TTCGGTGTGA TGTTCGAGAT 
CCTGATATGG TACATAACAC AGTGCTGGAA CTGATCAAAG TTGCAGGGCA TCCGGATGTG 
GTGATAAACA ACGCGGCAGG GAACTTCATT TCCCCCAGTG AGAGACTGAC TCCCAATGGC 
TGGAAGACCA TAACTGACAT AGTTCTCAAT GGCACAGCCT ATGTGACACT AGAAATTGGA 
AAGCAGCTAA TTAAAGCACA GAAAGGAGCT GCGTTTCTTG CCATCACTAC CATCTATGCT 
GAGAGTGGAT CAGGCTTTGT AATGCCAAGT TCTTCAGCCA AATCAGGCGT GGAAGCCATG 
AATAAGTCAC TTGCAGCTGA ATGGGGTAGA TATGGAATGC GTTTCAACAT AATTCAGCCA 
GGACCTATCA AAACCAAAGG AGCCTTTAGC CGTTTGGACC CGACTGGAAG ATTTGAGAAG 
GAGATGATTG ACAGAATCCC CTGTGGTCGT CTGGGAACTA TGGAGGAACT TGCAAATCTG 
GCCACTTTCC TATGCAGTGA TTATGCCTCT TGGATTAATG GAGCAGTCAT TAGATTTGAC 
GGTGGAGAGG AAGTATTTCT GTCAGGTGAA TTCAACTCTC TAAAGAAGGT CACCAAGGAG 
GAGTGGGATA TAATCGAAGG GCTCATCAGG AAGACAAAAG GCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(1)132-147(2017 01)
Zhou L,Dai H,Wu J,Zhou M,Yuan H,Du J,Yang L,Wu X,Xu H,Hua Y,Xu J,Zheng L,Shen B

Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
The Journal of comparative neurology519(11)2061-89(2011 Aug)
Boyle MP,Bernard A,Thompson CL,Ng L,Boe A,Mortrud M,Hawrylycz MJ,Jones AR,Hevner RF,Lein ES

Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
PLoS genetics5(7)e1000543(2009 Jul)
Miinalainen IJ,Schmitz W,Huotari A,Autio KJ,Soininen R,Ver Loren van Themaat E,Baes M,Herzig KH,Conzelmann E,Hiltunen JK

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
Molecular cell23(4)607-18(2006 Aug)
Kim SC,Sprung R,Chen Y,Xu Y,Ball H,Pei J,Cheng T,Kho Y,Xiao H,Xiao L,Grishin NV,White M,Yang XJ,Zhao Y

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Decr1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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