Paxbp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Paxbp1
Entrez Gene ID	67367
Full Name	PAX3 and PAX7 binding protein 1
Synonyms	1810007M14Rik,C21orf66,Gcfc,Gcfc1,Pax3/7bp
General protein information	Preferred Names PAX3 and PAX7 binding protein 1 Names PAX3- and PAX7-binding protein 1 GC-rich sequence DNA-binding factor 1 GC-rich sequence DNA-binding factor homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 C3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_026110.2	NP_080386.3	PAX3- and PAX7-binding protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GCFC1	XP_001164401.1
Bos taurus (cattle)	GCFC1	NP_001069157.3
Mus musculus (house mouse)	Paxbp1	NP_080386.3
Rattus norvegicus (Norway rat)	Paxbp1	XP_001057305.1
Danio rerio (zebrafish)	zgc:158234	NP_001073652.2
Caenorhabditis elegans (roundworm)	F43G9.12	NP_001250839.1
	GCFC1	XP_001094648.1
Canis lupus familiaris (dog)	PAXBP1	XP_852159.2
Gallus gallus (chicken)	GCFC1	XP_004938445.1
Xenopus tropicalis (tropical clawed frog)	paxbp1	NP_001120364.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002035	XP_321016.5
Homo sapiens (human)	PAXBP1	NP_057715.2
Drosophila melanogaster (fruit fly)	CG1965	NP_649689.1

Gene Ontology
Bibliography

Related articles in PubMed

Widespread and dynamic translational control of red blood cell development.
Alvarez-Dominguez JR, Zhang X, Hu W
Blood129(5)619-629(2017 02)

Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism.
Diao Y, Guo X, Li Y, Sun K, Lu L, Jiang L, Fu X, Zhu H, Sun H, Wang H, Wu Z
Cell stem cell11(2)231-41(2012 Aug)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

A gene expression map of human chromosome 21 orthologues in the mouse.
Gitton Y, Dahmane N, Baik S, Ruiz i Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML,
Nature420(6915)586-90(2002 Dec)

Human chromosome 21 gene expression atlas in the mouse.
Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A
Nature420(6915)582-6(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Pax3/7BP as an essential adaptor linking Pax3/7 with the histone 3 lysine 4 (H3K4) methyltransferase to regulate the proliferation of muscle precursor cells
Title: Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism.

The following Paxbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Paxbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01587	NM_026110.2 Latest version!	Mus musculus PAX3 and PAX7 binding protein 1 (Paxbp1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Paxbp1 ( NM_026110.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080386.3 Mus musculus PAX3 and PAX7 binding protein 1 (Paxbp1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu01587
Clone ID Related Accession (Same CDS sequence)	NM_026110.2
Accession Version	NM_026110.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2760bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	PAX3- and PAX7-binding protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC141885.3. On or before Apr 9, 2009 this sequence version replaced XM_904433.2, XM_358888.5, NM_026110.1. Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164141, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCCGAA AGGCCCGGCG GGTGAACGTG CGCAAGCGGA ACGACTCGGA GGAGGAGGAG 
CGGGAGCGCG ATGAGGAGCA GGAGCCGCCA CCGTTGCTGC CCCCGCCGGC CTCGGGAGAA 
GAGCCCGGCC CTGGCGGCGG CGACCGGGCC CCCGCGGGGG AGTCGCTCCT GGGCCCGGGG 
CCGCTGCCGC CGCCGCCCTC CGCGCACCAC CCGGGCCTCG GCGCTGAGGC CGGGGGCGGC 
ATCTCCGGCG GCGCGGAGCC CGGCAATGGG CTGAAGCCGC GCAAGAGGCC TCGCGAGAAC 
AAAGAGGTGC CCAGGGCCAG CCTGCTCAGC TTCCAAGACG AGGAGGAAGA AAATGAAGAA 
GTGTTCAAAG TAAAGAAATC AAGTTACAGC AAAAAGATAG TTAAATTGCT TAAGAAAGAA 
TATAAAGAAG ACCTTGAAAA ATCAAAGATC AAGACAGAAC TCAACACAGC AGCTGACAGT 
GACCAGCCTC TGGACAAAAC GTGTCATGCT AAGGACACAA ACCCAGAAGA TGGAGTTGTC 
ATCAGCGAGC ACGGTGAGGA TGAAATGGAC ATGGAGAGCG AGAAGGAGGA GGAGAAGCCC 
AAGGCCGGGG GCGCCTTCTC CAATGCTCTG TCTTCCCTGA ACGTGCTCCG CCCAGGAGAA 
ATCCCAGATG CAGCTTTCAT ACATGCTGCA AGAAAGAAGC GACAACTGGC CCGGGAGCTG 
GGCGACTTCA CGCCTCACGA CAGTGAGCCT GGCAAAGGCC GCCTCGTCCG CGAGGACGAG 
AATGATGCCA GCGACGATGA GGACGATGAT GAGAAGCGCC GGATCGTTTT TTCTGTGAAG 
GAAAAGTCAC AAAGACAAAA GATCGCTGAG GAGATAGGTA TTGAGGGGAG TGACGATGAC 
GCGTTAGTAA CTGGAGAGCA AGACGAGGAG CTCAGCCGCT GGGAGCAGGA GCAGATTAGA 
AAAGGAATTA ACATCCCTCA GGTTCAAGCA AGTCAGCCCA GTGAAGTGAA TGTGTACTAC 
CAGAACACCT ACCAGACAAT GCCTTACGGT GCATCCTATG GCATACCGTA TAGTTACACA 
GCCTATGGAT CATCAGATGC CAAGTCTCAA AAAACAGATA ATACAGTCCC TTTCAAAACT 
CCCAGTAATG AGATGGCTCC CGTTACTATT GATTTGGTAA AGAGACAGCT TAAAGACAGG 
TTGGACTCCA TGAAAGAATT GCACAAAACC AATCAACAGC AGCATGAAAA ACATCTGCAA 
AGCCGAGTGG ACTCCACCAG GGCTATTGAG AGATTAGAAG GGTCTTCTGG GGGTATTGGT 
GAACGGTATA AATTTTTGCA AGAAATGCGA GGGTATGTCC AAGACTTGCT TGAGTGTTTC 
AGTGAAAAGG TGCCACTGAT TAATGAACTT GAATCAGCAA TACATCAGCT GTACAAACAG 
CGAGCTTCCC GCCTTGTCCA AAGACGACAA GATGATATTA AAGATGAATC TTCGGAGTTT 
TCAAGCCATT CAAATAAAGC TTTGATGGCA CCAAATCTTG ATTCCTTTGG ACGTGATCGG 
GCACTTTATC AAGAACATGC AAAACGTCGG ATTGCAGAGC GGGAAGCCAG GAGGACTCGC 
CGTAGGCAAG CCAGAGAGCA AACCGGTCAG ATGGCAGATC ACCTGGAAGG CCTGTCCAGT 
GATGATGAAG AGACGTCTAC AGATATTACT AATTTCAATC TGGAGAAAGA TCGAATTTTG 
AAAGAGTCTA GCAAAGTTTT TGAAGATGTC CTTGAGAGTT TCTATTCAAT TGACTGCATT 
AAAGCACAGT TTGAAGCATG GCGTTCAAAA TACTACATGT CCTATAAGGA TGCTTATATT 
GGTCTTTGTC TGCCCAAACT GTTCAACCCC CTAATCAGAC TTCAGCTTCT CACCTGGACT 
CCTCTTGAGG CAAAATGCCG TGACTTTGAA ACCATGCTGT GGTTTGAATC TCTGCTGTTC 
TATGGCTGTG AAGACCGAGA GCAGGAGAAG GATGAGGCTG ACGTTGCTCT GCTGCCCACC 
ATTGTGGAGA AGGTCATTCT CCCCAAGCTG ACAGTGATAG CTGAAACCAT GTGGGATCCC 
TTTTCTACAA CACAGACTTC AAGGATGGTT GGAATCACAA TGAAATTAAT AAATGGCTAC 
CCCTCAGTAG TCAATGCAGA CAATAAAAAC ACGCAGGTAT ACCTTAAAGC TCTTTTACTG 
AGGATGAGAA GAACTTTAGA TGATGATGTA TTTATGCCCC TATATCCCAA AAATGTCTTA 
GAAAATAAAA ATTCTGGGCC TTACTTATTT TTTCAACGAC AGTTTTGGTC GTCTGTTAAG 
CTATTGGGAA ATTTTCTTCA GTGGTATGGC ATTTTCTCAA ACAAAACTCT TCAGGAGTTA 
TCAATAGATG GCTTGTTAAA CAGATACATC CTTATGGCTT TTCAGAACTC AGAATACGGA 
GATGACAGCA TCAGAAAAGC CCAAAATGTA ATCAACTGTT TCCCTAAACA GTGGTTTGTG 
AATCTGAAAG GAGAAAGAAC TATTTCTCAG TTAGAAAATT TTTGCCGATA TCTTGTACAT 
TTAGCAGATA CAATTTACAG GAACAGTATT GGGTGCTCTG ATGTGGAAAA AAGAAATGCA 
AGGGAAAATA TAAAACAGAT AGTAAAACTT CTTGCAAGCG TTCGGGCTTT GGATCACGCT 
ATATCTGTTG CAAGTGACCA CAATGTGAAG GAAGTCAAGT CTCTGATTGA AGGAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080386.3
CDS	26..2785
Translation	MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPASGEEPGPGGGDRAPAGESLLGPGPLPPPPSAHHPGLGAEAGGGISGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNTAADSDQPLDKTCHAKDTNPEDGVVISEHGEDEMDMESEKEEEKPKAGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQLARELGDFTPHDSEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPSEVNVYYQNTYQTMPYGASYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMAPVTIDLVKRQLKDRLDSMKELHKTNQQQHEKHLQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRRQAREQTGQMADHLEGLSSDDEETSTDITNFNLEKDRILKESSKVFEDVLESFYSIDCIKAQFEAWRSKYYMSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFETMLWFESLLFYGCEDREQEKDEADVALLPTIVEKVILPKLTVIAETMWDPFSTTQTSRMVGITMKLINGYPSVVNADNKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKLLGNFLQWYGIFSNKTLQELSIDGLLNRYILMAFQNSEYGDDSIRKAQNVINCFPKQWFVNLKGERTISQLENFCRYLVHLADTIYRNSIGCSDVEKRNARENIKQIVKLLASVRALDHAISVASDHNVKEVKSLIEGK

Target ORF information:

RefSeq Version	NM_026110.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus PAX3 and PAX7 binding protein 1 (Paxbp1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026110.2

ORF Insert Sequence:

ATGTTCCGAA AGGCCCGGCG GGTGAACGTG CGCAAGCGGA ACGACTCGGA GGAGGAGGAG 
CGGGAGCGCG ATGAGGAGCA GGAGCCGCCA CCGTTGCTGC CCCCGCCGGC CTCGGGAGAA 
GAGCCCGGCC CTGGCGGCGG CGACCGGGCC CCCGCGGGGG AGTCGCTCCT GGGCCCGGGG 
CCGCTGCCGC CGCCGCCCTC CGCGCACCAC CCGGGCCTCG GCGCTGAGGC CGGGGGCGGC 
ATCTCCGGCG GCGCGGAGCC CGGCAATGGG CTGAAGCCGC GCAAGAGGCC TCGCGAGAAC 
AAAGAGGTGC CCAGGGCCAG CCTGCTCAGC TTCCAAGACG AGGAGGAAGA AAATGAAGAA 
GTGTTCAAAG TAAAGAAATC AAGTTACAGC AAAAAGATAG TTAAATTGCT TAAGAAAGAA 
TATAAAGAAG ACCTTGAAAA ATCAAAGATC AAGACAGAAC TCAACACAGC AGCTGACAGT 
GACCAGCCTC TGGACAAAAC GTGTCATGCT AAGGACACAA ACCCAGAAGA TGGAGTTGTC 
ATCAGCGAGC ACGGTGAGGA TGAAATGGAC ATGGAGAGCG AGAAGGAGGA GGAGAAGCCC 
AAGGCCGGGG GCGCCTTCTC CAATGCTCTG TCTTCCCTGA ACGTGCTCCG CCCAGGAGAA 
ATCCCAGATG CAGCTTTCAT ACATGCTGCA AGAAAGAAGC GACAACTGGC CCGGGAGCTG 
GGCGACTTCA CGCCTCACGA CAGTGAGCCT GGCAAAGGCC GCCTCGTCCG CGAGGACGAG 
AATGATGCCA GCGACGATGA GGACGATGAT GAGAAGCGCC GGATCGTTTT TTCTGTGAAG 
GAAAAGTCAC AAAGACAAAA GATCGCTGAG GAGATAGGTA TTGAGGGGAG TGACGATGAC 
GCGTTAGTAA CTGGAGAGCA AGACGAGGAG CTCAGCCGCT GGGAGCAGGA GCAGATTAGA 
AAAGGAATTA ACATCCCTCA GGTTCAAGCA AGTCAGCCCA GTGAAGTGAA TGTGTACTAC 
CAGAACACCT ACCAGACAAT GCCTTACGGT GCATCCTATG GCATACCGTA TAGTTACACA 
GCCTATGGAT CATCAGATGC CAAGTCTCAA AAAACAGATA ATACAGTCCC TTTCAAAACT 
CCCAGTAATG AGATGGCTCC CGTTACTATT GATTTGGTAA AGAGACAGCT TAAAGACAGG 
TTGGACTCCA TGAAAGAATT GCACAAAACC AATCAACAGC AGCATGAAAA ACATCTGCAA 
AGCCGAGTGG ACTCCACCAG GGCTATTGAG AGATTAGAAG GGTCTTCTGG GGGTATTGGT 
GAACGGTATA AATTTTTGCA AGAAATGCGA GGGTATGTCC AAGACTTGCT TGAGTGTTTC 
AGTGAAAAGG TGCCACTGAT TAATGAACTT GAATCAGCAA TACATCAGCT GTACAAACAG 
CGAGCTTCCC GCCTTGTCCA AAGACGACAA GATGATATTA AAGATGAATC TTCGGAGTTT 
TCAAGCCATT CAAATAAAGC TTTGATGGCA CCAAATCTTG ATTCCTTTGG ACGTGATCGG 
GCACTTTATC AAGAACATGC AAAACGTCGG ATTGCAGAGC GGGAAGCCAG GAGGACTCGC 
CGTAGGCAAG CCAGAGAGCA AACCGGTCAG ATGGCAGATC ACCTGGAAGG CCTGTCCAGT 
GATGATGAAG AGACGTCTAC AGATATTACT AATTTCAATC TGGAGAAAGA TCGAATTTTG 
AAAGAGTCTA GCAAAGTTTT TGAAGATGTC CTTGAGAGTT TCTATTCAAT TGACTGCATT 
AAAGCACAGT TTGAAGCATG GCGTTCAAAA TACTACATGT CCTATAAGGA TGCTTATATT 
GGTCTTTGTC TGCCCAAACT GTTCAACCCC CTAATCAGAC TTCAGCTTCT CACCTGGACT 
CCTCTTGAGG CAAAATGCCG TGACTTTGAA ACCATGCTGT GGTTTGAATC TCTGCTGTTC 
TATGGCTGTG AAGACCGAGA GCAGGAGAAG GATGAGGCTG ACGTTGCTCT GCTGCCCACC 
ATTGTGGAGA AGGTCATTCT CCCCAAGCTG ACAGTGATAG CTGAAACCAT GTGGGATCCC 
TTTTCTACAA CACAGACTTC AAGGATGGTT GGAATCACAA TGAAATTAAT AAATGGCTAC 
CCCTCAGTAG TCAATGCAGA CAATAAAAAC ACGCAGGTAT ACCTTAAAGC TCTTTTACTG 
AGGATGAGAA GAACTTTAGA TGATGATGTA TTTATGCCCC TATATCCCAA AAATGTCTTA 
GAAAATAAAA ATTCTGGGCC TTACTTATTT TTTCAACGAC AGTTTTGGTC GTCTGTTAAG 
CTATTGGGAA ATTTTCTTCA GTGGTATGGC ATTTTCTCAA ACAAAACTCT TCAGGAGTTA 
TCAATAGATG GCTTGTTAAA CAGATACATC CTTATGGCTT TTCAGAACTC AGAATACGGA 
GATGACAGCA TCAGAAAAGC CCAAAATGTA ATCAACTGTT TCCCTAAACA GTGGTTTGTG 
AATCTGAAAG GAGAAAGAAC TATTTCTCAG TTAGAAAATT TTTGCCGATA TCTTGTACAT 
TTAGCAGATA CAATTTACAG GAACAGTATT GGGTGCTCTG ATGTGGAAAA AAGAAATGCA 
AGGGAAAATA TAAAACAGAT AGTAAAACTT CTTGCAAGCG TTCGGGCTTT GGATCACGCT 
ATATCTGTTG CAAGTGACCA CAATGTGAAG GAAGTCAAGT CTCTGATTGA AGGAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread and dynamic translational control of red blood cell development.
Blood129(5)619-629(2017 02)
Alvarez-Dominguez JR,Zhang X,Hu W

Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism.
Cell stem cell11(2)231-41(2012 Aug)
Diao Y,Guo X,Li Y,Sun K,Lu L,Jiang L,Fu X,Zhu H,Sun H,Wang H,Wu Z

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

A gene expression map of human chromosome 21 orthologues in the mouse.
Nature420(6915)586-90(2002 Dec)
Gitton Y,Dahmane N,Baik S,Ruiz i Altaba A,Neidhardt L,Scholze M,Herrmann BG,Kahlem P,Benkahla A,Schrinner S,Yildirimman R,Herwig R,Lehrach H,Yaspo ML,

Human chromosome 21 gene expression atlas in the mouse.
Nature420(6915)582-6(2002 Dec)
Reymond A,Marigo V,Yaylaoglu MB,Leoni A,Ucla C,Scamuffa N,Caccioppoli C,Dermitzakis ET,Lyle R,Banfi S,Eichele G,Antonarakis SE,Ballabio A

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Paxbp1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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