Fam220a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fam220a
Entrez Gene ID	67238
Full Name	family with sequence similarity 220, member A
Synonyms	1500026F15Rik,2810453I06Rik,AW047776,Acpin1,Sipar
General protein information	Preferred Names family with sequence similarity 220, member A Names protein FAM220A STAT3-interacting protein as a repressor acrosomal protein ACPIN1 salivary gland specific protein SAGSIN1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 G2

mRNA and Protein(s)

mRNA	Protein	Name
NM_133703.5	NP_598464.3	protein FAM220A
NM_026050.2	NP_080326.2	protein FAM220A
NM_133703.4	NP_598464.3	protein FAM220A
NM_026050.3	NP_080326.2	protein FAM220A

Pathways from BioSystems

Homologies

Homo sapiens (human)	FAM220A	NP_001032240.1
Canis lupus familiaris (dog)	FAM220A	XP_005621180.1
Rattus norvegicus (Norway rat)	Fam220a	NP_001017485.1
Pan troglodytes (chimpanzee)	FAM220A	XP_003318353.1
	LOC703785	XP_001090217.2
Mus musculus (house mouse)	Fam220a	NP_598464.3

Gene Ontology
Bibliography

Related articles in PubMed

Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.
Ren F, Geng Y, Minami T, Qiu Y, Feng Y, Liu C, Zhao J, Wang Y, Fan X, Wang Y, Li M, Li J, Chang Z
FEBS letters589(15)1890-6(2015 Jul)

SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.
Ren F, Su F, Ning H, Wang Y, Geng Y, Feng Y, Wang Y, Zhang Y, Jin Z, Li Y, Jia B, Chang Z
Cellular signalling25(11)2272-80(2013 Nov)

Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein.
Ueda T, Manabe H, Tokuhiro K, Hirose M, Matsuoka Y, Miyagawa Y, Tsujimura A, Fujita K, Wada M, Okuyama A, Nishimune Y, Tanaka H
International journal of urology : official journal of the Japanese Urological Association16(7)639-46(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results suggest that SIPAR terminates the activation of STAT3 through a dephosphorylation process that is dependent upon interaction with TC45 in the nucleus
Title: Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.

SIPAR, functioning as a new negative regulator, inhibits STAT3 activity by enhancing its dephosphorylation and represses melanoma progression.
Title: SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.

The two ORFs on the Acpin1 mRNA are independently translated in differentiated cells
Title: Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein.

The following Fam220a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fam220a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15218	NM_026050.3 Latest version!	Mus musculus family with sequence similarity 220, member A (Fam220a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu15218	NM_133703.5 Latest version!	Mus musculus family with sequence similarity 220, member A (Fam220a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OMu15218	NM_133703.4	Mus musculus family with sequence similarity 220, member A (Fam220a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu15218	NM_026050.2	Mus musculus family with sequence similarity 220, member A (Fam220a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fam220a ( NM_133703.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598464.3 Mus musculus family with sequence similarity 220, member A (Fam220a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu15218
Clone ID Related Accession (Same CDS sequence)	NM_133703.5 , NM_026050.2 , NM_133703.4 , NM_026050.3
Accession Version	NM_133703.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-30
Organism	Mus musculus(house mouse)
Product	protein FAM220A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC217112.7. On Jan 31, 2019 this sequence version replaced NM_133703.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK075875.1, BC100440.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598464.3
CDS	494..1276
Translation	MKAGRGTLGVCLAKQSQGGDPDKLACGLKKRSQKRNPSPSVVPSWTDQPVADSHGKSRATGAAASEMKHGQSKASLLHHGGFKVLQSLKGSVGRSSAPAASLGKAVALSPAPSEEQLAGMSHGIGDALGSDWPGREPRATDNRGQYLKGESWVSGRPGHPKLREVGFLRGEPPSAGPKGLGTWSELSHRYFELGQLPYAYPYYKVLPEGELRCVSLDRFNPGLSEETVEDEKTLKFFRWSADSRGVTGSAIFQISKSLMP

Target ORF information:

RefSeq Version	NM_133703.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus family with sequence similarity 220, member A (Fam220a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133703.5

ORF Insert Sequence:

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fam220a ( NM_026050.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080326.2 Mus musculus family with sequence similarity 220, member A (Fam220a), mRNA.

Price & Availability↑

CloneID	OMu15218
Clone ID Related Accession (Same CDS sequence)	NM_133703.5 , NM_026050.2 , NM_133703.4 , NM_026050.3
Accession Version	NM_026050.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Mus musculus(house mouse)
Product	protein FAM220A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY062850.1, AK014805.1 and BC085297.1. On Jan 17, 2008 this sequence version replaced NM_026050.1. Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK156614.1, AK014805.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080326.2
CDS	641..1423
Translation	MKAGRGTLGVCLAKQSQGGDPDKLACGLKKRSQKRNPSPSVVPSWTDQPVADSHGKSRATGAAASEMKHGQSKASLLHHGGFKVLQSLKGSVGRSSAPAASLGKAVALSPAPSEEQLAGMSHGIGDALGSDWPGREPRATDNRGQYLKGESWVSGRPGHPKLREVGFLRGEPPSAGPKGLGTWSELSHRYFELGQLPYAYPYYKVLPEGELRCVSLDRFNPGLSEETVEDEKTLKFFRWSADSRGVTGSAIFQISKSLMP

Target ORF information:

RefSeq Version	NM_026050.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus family with sequence similarity 220, member A (Fam220a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026050.2

ORF Insert Sequence:

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fam220a ( NM_133703.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598464.3 Mus musculus family with sequence similarity 220, member A (Fam220a), mRNA.

Price & Availability↑

CloneID	OMu15218
Clone ID Related Accession (Same CDS sequence)	NM_133703.5 , NM_026050.2 , NM_133703.4 , NM_026050.3
Accession Version	NM_133703.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Mus musculus(house mouse)
Product	protein FAM220A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY062850.1, BC100440.1 and BC085297.1. On Jan 17, 2008 this sequence version replaced NM_133703.3. Transcript Variant: This variant (2) lacks an internal 5' UTR exon, as compared to variant 1. ##Evidence-Data-START## Transcript exon combination :: BC085297.1, AK076127.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598464.3
CDS	508..1290
Translation	MKAGRGTLGVCLAKQSQGGDPDKLACGLKKRSQKRNPSPSVVPSWTDQPVADSHGKSRATGAAASEMKHGQSKASLLHHGGFKVLQSLKGSVGRSSAPAASLGKAVALSPAPSEEQLAGMSHGIGDALGSDWPGREPRATDNRGQYLKGESWVSGRPGHPKLREVGFLRGEPPSAGPKGLGTWSELSHRYFELGQLPYAYPYYKVLPEGELRCVSLDRFNPGLSEETVEDEKTLKFFRWSADSRGVTGSAIFQISKSLMP

Target ORF information:

RefSeq Version	NM_133703.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus family with sequence similarity 220, member A (Fam220a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133703.4

ORF Insert Sequence:

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fam220a ( NM_026050.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080326.2 Mus musculus family with sequence similarity 220, member A (Fam220a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15218
Clone ID Related Accession (Same CDS sequence)	NM_133703.5 , NM_026050.2 , NM_133703.4 , NM_026050.3
Accession Version	NM_026050.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-30
Organism	Mus musculus(house mouse)
Product	protein FAM220A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC217112.7. On Jan 31, 2019 this sequence version replaced NM_026050.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK156614.1, AK014805.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080326.2
CDS	627..1409
Translation	MKAGRGTLGVCLAKQSQGGDPDKLACGLKKRSQKRNPSPSVVPSWTDQPVADSHGKSRATGAAASEMKHGQSKASLLHHGGFKVLQSLKGSVGRSSAPAASLGKAVALSPAPSEEQLAGMSHGIGDALGSDWPGREPRATDNRGQYLKGESWVSGRPGHPKLREVGFLRGEPPSAGPKGLGTWSELSHRYFELGQLPYAYPYYKVLPEGELRCVSLDRFNPGLSEETVEDEKTLKFFRWSADSRGVTGSAIFQISKSLMP

Target ORF information:

RefSeq Version	NM_026050.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus family with sequence similarity 220, member A (Fam220a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026050.3

ORF Insert Sequence:

ATGAAGGCTG GGAGAGGGAC CCTGGGTGTC TGCCTGGCCA AACAGTCACA AGGAGGTGAC 
CCGGACAAAC TAGCATGTGG CCTTAAGAAA AGAAGTCAGA AGAGGAACCC CAGCCCATCA 
GTTGTGCCTT CTTGGACAGA CCAGCCTGTA GCAGATAGCC ATGGAAAGTC ACGGGCCACG 
GGGGCAGCAG CCTCAGAAAT GAAGCATGGT CAGAGCAAGG CCAGCCTCCT GCATCATGGT 
GGCTTCAAAG TGCTTCAGTC TCTGAAGGGA TCAGTGGGGA GGAGTTCAGC CCCAGCAGCC 
TCCCTCGGCA AGGCTGTGGC TCTGTCCCCT GCTCCTTCAG AAGAGCAACT AGCCGGGATG 
TCCCATGGCA TCGGGGATGC ACTAGGAAGT GACTGGCCAG GAAGAGAGCC CAGAGCCACA 
GACAACCGTG GACAGTACCT CAAAGGAGAG TCCTGGGTGT CAGGACGGCC AGGCCATCCA 
AAACTGAGGG AAGTGGGATT CCTAAGAGGT GAACCACCAA GTGCTGGCCC CAAGGGGCTA 
GGCACCTGGT CAGAACTGTC TCACCGATAC TTTGAGCTGG GCCAGCTGCC ATATGCTTAC 
CCCTATTATA AAGTTCTCCC AGAAGGCGAG CTGAGGTGTG TGTCCCTTGA CCGTTTCAAT 
CCCGGGCTTT CAGAGGAAAC AGTAGAAGAT GAGAAAACTC TCAAGTTCTT CAGATGGTCC 
GCAGATAGTC GTGGGGTCAC TGGCTCTGCA ATCTTCCAGA TTAGCAAGTC TCTGATGCCA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.
FEBS letters589(15)1890-6(2015 Jul)
Ren F,Geng Y,Minami T,Qiu Y,Feng Y,Liu C,Zhao J,Wang Y,Fan X,Wang Y,Li M,Li J,Chang Z

SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.
Cellular signalling25(11)2272-80(2013 Nov)
Ren F,Su F,Ning H,Wang Y,Geng Y,Feng Y,Wang Y,Zhang Y,Jin Z,Li Y,Jia B,Chang Z

Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein.
International journal of urology : official journal of the Japanese Urological Association16(7)639-46(2009 Jul)
Ueda T,Manabe H,Tokuhiro K,Hirose M,Matsuoka Y,Miyagawa Y,Tsujimura A,Fujita K,Wada M,Okuyama A,Nishimune Y,Tanaka H

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Fam220a cDNA ORF clone, Mus musculus(house mouse)

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