Lsm1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsm1
Entrez Gene ID	67207
Full Name	LSM1 homolog, mRNA degradation associated
Synonyms	2810025O06Rik,CASM
General protein information	Preferred Names LSM1 homolog, mRNA degradation associated Names U6 snRNA-associated Sm-like protein LSm1 LSM1 homolog, U6 small nuclear RNA associated U6 small nuclear RNA associated
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 A2

mRNA and Protein(s)

mRNA	Protein	Name
XM_011242156.3	XP_011240458.1	U6 snRNA-associated Sm-like protein LSm1 isoform X1
XM_011242156.2	XP_011240458.1	U6 snRNA-associated Sm-like protein LSm1 isoform X1
NM_026032.1	NP_080308.1	U6 snRNA-associated Sm-like protein LSm1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LSM1	XP_532806.3
Bos taurus (cattle)	LSM1	NP_001017952.1
Eremothecium gossypii	AGOS_AFL212C	NP_985338.1
Schizosaccharomyces pombe (fission yeast)	lsm1	NP_595520.1
Arabidopsis thaliana (thale cress)	AT3G14080	NP_850580.1
Homo sapiens (human)	LSM1	NP_055277.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001686	XP_321407.3
Caenorhabditis elegans (roundworm)	lsm-1	NP_496385.1
Mus musculus (house mouse)	Lsm1	NP_080308.1
Rattus norvegicus (Norway rat)	Lsm1	NP_001102346.1
Danio rerio (zebrafish)	lsm1	NP_001003551.1
Drosophila melanogaster (fruit fly)	LSm1	NP_611559.1
Kluyveromyces lactis	KLLA0E15159g	XP_454633.1
Magnaporthe oryzae (rice blast fungus)	MGG_03195	XP_003716791.1
Xenopus tropicalis (tropical clawed frog)	lsm1	NP_001011191.1
Pan troglodytes (chimpanzee)	LSM1	XP_001170479.1
Saccharomyces cerevisiae (baker's yeast)	LSM1	NP_012411.1
Oryza sativa (rice)	Os04g0445800	NP_001052905.1
Gallus gallus (chicken)	LSM1	XP_424387.4

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Yang G, Smibert CA, Kaplan DR, Miller FD
Neuron84(4)723-39(2014 Nov)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.
Hoefig KP, Rath N, Heinz GA, Wolf C, Dameris J, Schepers A, Kremmer E, Ansel KM, Heissmeyer V
Nature structural & molecular biology20(1)73-81(2013 Jan)

Minor spliceosome components are predominantly localized in the nucleus.
Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Per?l? N, Nymark M, Turunen JJ, L?hrmann R, Frilander MJ
Proceedings of the National Academy of Sciences of the United States of America105(25)8655-60(2008 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lsm1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsm1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01438	NM_026032.1 Latest version!	Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu70097	XM_011242156.3 Latest version!	Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu70097	XM_011242156.2	Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsm1 ( XM_011242156.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011240458.1 Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70097
Clone ID Related Accession (Same CDS sequence)	XM_011242156.3 , XM_011242156.2
Accession Version	XM_011242156.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011242156.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTATA TGCCCGGCAC CGCCAGCCTC ATCGAGGACA TCGACAAAAA GCACTTGGTC 
CTACTTCGAG ATGGAAGAAC ACTTATAGGT TTTTTAAGAA GCATTGATCA ATTTGCTAAC 
TTAGTGCTCC ATCAGACTGT GGAGCGAATT CATGTGGGCA AAAAGTACGG TGATATTCCT 
CGAGGGATTT TCGTGGTCAG AGGAGAGAAT GTGGTCCTAC TAGGAGAAAT AGCACCAGTC 
AGGACCAGCA AGGACACCAG GAGTTCTCTG CCATGCCTCT CTCAACGAAG TGGAGATCAG 
CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011240458.1
CDS	137..442
Translation	MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIAPVRTSKDTRSSLPCLSQRSGDQR

Target ORF information:

RefSeq Version	XM_011242156.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242156.2

ORF Insert Sequence:

ATGAACTATA TGCCCGGCAC CGCCAGCCTC ATCGAGGACA TCGACAAAAA GCACTTGGTC 
CTACTTCGAG ATGGAAGAAC ACTTATAGGT TTTTTAAGAA GCATTGATCA ATTTGCTAAC 
TTAGTGCTCC ATCAGACTGT GGAGCGAATT CATGTGGGCA AAAAGTACGG TGATATTCCT 
CGAGGGATTT TCGTGGTCAG AGGAGAGAAT GTGGTCCTAC TAGGAGAAAT AGCACCAGTC 
AGGACCAGCA AGGACACCAG GAGTTCTCTG CCATGCCTCT CTCAACGAAG TGGAGATCAG 
CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm1 ( NM_026032.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080308.1 Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), mRNA.

Price & Availability↑

CloneID	OMu01438
Clone ID Related Accession (Same CDS sequence)	NM_026032.1
Accession Version	NM_026032.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK041290.1. On or before Jul 24, 2006 this sequence version replaced XM_357867.4, XM_987686.1, XM_911934.2, XM_922221.2, XM_983898.1. ##Evidence-Data-START## Transcript exon combination :: AK041290.1, BC021460.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAACTATA TGCCCGGCAC CGCCAGCCTC ATCGAGGACA TCGACAAAAA GCACTTGGTC 
CTACTTCGAG ATGGAAGAAC ACTTATAGGT TTTTTAAGAA GCATTGATCA ATTTGCTAAC 
TTAGTGCTCC ATCAGACTGT GGAGCGAATT CATGTGGGCA AAAAGTACGG TGATATTCCT 
CGAGGGATTT TCGTGGTCAG AGGAGAGAAT GTGGTCCTAC TAGGAGAAAT AGACCTGGAG 
AAGGAGAGTG ACACGCCCCT TCAGCAAGTG TCTATTGAAG AGATCCTAGA GGAACAGAGG 
GTGCAACAGC AGACCAGACT GGAGGCAGAG AAGCTGAAGG TCCAGACCCT TAAAGATCGG 
GGCCTTTCCA TTCCTCGCGC AGACACTCTG GACGAGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080308.1
CDS	82..483
Translation	MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVQQQTRLEAEKLKVQTLKDRGLSIPRADTLDEY

Target ORF information:

RefSeq Version	NM_026032.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026032.1

ORF Insert Sequence:

ATGAACTATA TGCCCGGCAC CGCCAGCCTC ATCGAGGACA TCGACAAAAA GCACTTGGTC 
CTACTTCGAG ATGGAAGAAC ACTTATAGGT TTTTTAAGAA GCATTGATCA ATTTGCTAAC 
TTAGTGCTCC ATCAGACTGT GGAGCGAATT CATGTGGGCA AAAAGTACGG TGATATTCCT 
CGAGGGATTT TCGTGGTCAG AGGAGAGAAT GTGGTCCTAC TAGGAGAAAT AGACCTGGAG 
AAGGAGAGTG ACACGCCCCT TCAGCAAGTG TCTATTGAAG AGATCCTAGA GGAACAGAGG 
GTGCAACAGC AGACCAGACT GGAGGCAGAG AAGCTGAAGG TCCAGACCCT TAAAGATCGG 
GGCCTTTCCA TTCCTCGCGC AGACACTCTG GACGAGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm1 ( XM_011242156.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011240458.1 Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70097
Clone ID Related Accession (Same CDS sequence)	XM_011242156.3 , XM_011242156.2
Accession Version	XM_011242156.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011242156.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTATA TGCCCGGCAC CGCCAGCCTC ATCGAGGACA TCGACAAAAA GCACTTGGTC 
CTACTTCGAG ATGGAAGAAC ACTTATAGGT TTTTTAAGAA GCATTGATCA ATTTGCTAAC 
TTAGTGCTCC ATCAGACTGT GGAGCGAATT CATGTGGGCA AAAAGTACGG TGATATTCCT 
CGAGGGATTT TCGTGGTCAG AGGAGAGAAT GTGGTCCTAC TAGGAGAAAT AGCACCAGTC 
AGGACCAGCA AGGACACCAG GAGTTCTCTG CCATGCCTCT CTCAACGAAG TGGAGATCAG 
CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011240458.1
CDS	355..660
Translation	MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIAPVRTSKDTRSSLPCLSQRSGDQR

Target ORF information:

RefSeq Version	XM_011242156.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011242156.3

ORF Insert Sequence:

ATGAACTATA TGCCCGGCAC CGCCAGCCTC ATCGAGGACA TCGACAAAAA GCACTTGGTC 
CTACTTCGAG ATGGAAGAAC ACTTATAGGT TTTTTAAGAA GCATTGATCA ATTTGCTAAC 
TTAGTGCTCC ATCAGACTGT GGAGCGAATT CATGTGGGCA AAAAGTACGG TGATATTCCT 
CGAGGGATTT TCGTGGTCAG AGGAGAGAAT GTGGTCCTAC TAGGAGAAAT AGCACCAGTC 
AGGACCAGCA AGGACACCAG GAGTTCTCTG CCATGCCTCT CTCAACGAAG TGGAGATCAG 
CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Neuron84(4)723-39(2014 Nov)
Yang G,Smibert CA,Kaplan DR,Miller FD

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.
Nature structural & molecular biology20(1)73-81(2013 Jan)
Hoefig KP,Rath N,Heinz GA,Wolf C,Dameris J,Schepers A,Kremmer E,Ansel KM,Heissmeyer V

Minor spliceosome components are predominantly localized in the nucleus.
Proceedings of the National Academy of Sciences of the United States of America105(25)8655-60(2008 Jun)
Pessa HK,Will CL,Meng X,Schneider C,Watkins NJ,Per?l? N,Nymark M,Turunen JJ,L?hrmann R,Frilander MJ

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Lsm1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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