Herc6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Herc6
Entrez Gene ID	67138
Full Name	hect domain and RLD 6
Synonyms	1700121D12Rik,2510038N07Rik,4930427L17Rik,AI451296,CEB1,Herc5
General protein information	Preferred Names hect domain and RLD 6 Names E3 ISG15--protein ligase Herc6 hect domain and RLD 5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 B3\|6

mRNA and Protein(s)

mRNA	Protein	Name
NM_025992.2	NP_080268.1	E3 ISG15--protein ligase Herc6

Pathways from BioSystems

Homologies

	HERC6	XP_002804182.1
Bos taurus (cattle)	HERC6	NP_001179573.1
Homo sapiens (human)	HERC6	NP_060382.3
Canis lupus familiaris (dog)	HERC6	XP_851549.1
Pan troglodytes (chimpanzee)	HERC6	XP_001160851.1
Xenopus tropicalis (tropical clawed frog)	herc6	XP_002938670.2
Mus musculus (house mouse)	Herc6	NP_080268.1
Rattus norvegicus (Norway rat)	Herc6	XP_006236645.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.
Arimoto K, Hishiki T, Kiyonari H, Abe T, Cheng C, Yan M, Fan JB, Futakuchi M, Tsuda H, Murakami Y, Suzuki H, Zhang DE, Shimotohno K
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research35(5)351-8(2015 May)

Mice without macroH2A histone variants.
Pehrson JR, Changolkar LN, Costanzi C, Leu NA
Molecular and cellular biology34(24)4523-33(2014 Dec)

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T
Cancer cell24(3)305-17(2013 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that in addition to promoting protein ISGylation, Herc6 has a novel and protein ISGylation-independent function in the male reproductive system.
Title: Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.

Data show that the HerC6 N-terminal RCC1-like domain (RLD) allows ISG15 conjugation.
Title: HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells.

mHERC6 is essential for endogenous murine ISGylation and thus represents the dominant ISG15 E3 ligase in mice.
Title: mHERC6 is the essential ISG15 E3 ligase in the murine system.

Expression of the Herc5-mediated ubiquitin-like protein ISGylation system can distinctly potentiate interferon-beta-induced antiviral effects against influenza A virus.
Title: Herc5 attenuates influenza A virus by catalyzing ISGylation of viral NS1 protein.

The following Herc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Herc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18367	NM_025992.2 Latest version!	Mus musculus hect domain and RLD 6 (Herc6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Herc6 ( NM_025992.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080268.1 Mus musculus hect domain and RLD 6 (Herc6), mRNA.

Price & Availability↑

CloneID	OMu18367
Clone ID Related Accession (Same CDS sequence)	NM_025992.2
Accession Version	NM_025992.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3012bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-22
Organism	Mus musculus(house mouse)
Product	E3 ISG15--protein ligase Herc6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC142212.4 and AC127307.3. On Jul 9, 2009 this sequence version replaced NM_025992.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK147960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGTATTTCA GCTGGGCTGC AGGAAGCCGG AAGCCTCGGC GCCTGAAGGC GGGAACCAGC 
GGCATTGAAC TCTTGCAGGC AGCCAGCGGG GAACACCACT CGCTCCTACT GTTCAGCAAC 
CACAGGGTGT ATTCCTGCGG GGACAACAGC TGGGGACAGC TGGGCCAGAG GAGAGACCAG 
AGTACCGAAA GGCCAGAACC AATTCAGGCA CTGAATGATC TGCATGTTGA CCTGGTGAGC 
TGTGGGAAGG AACACTCTGT GGCTGTCTGC CACAAAGGAA AGGTCTTCGC TTGGGGAGCC 
GGTTCTGAAG GGCAGCTGGG GATTGGAGAA TTTAAGGAAA TAAGCTTTAT GCCTACGAAA 
ATAAAAGCTC TGGCTGGCAT AAAAATAATC CAAGTTTCCT GTGGACACTA CCACTCTTTG 
GCCTTATCAG AAGATGGCCA CGTGTTTTCA TGGGGAAGGA ACAGTGAAGG ACAACTGGGC 
CTGGGGAAGA ATTCCCGTTC TCAAGCTATT CCACAGAAGG TGAAGTCTCT GGAGGGGATC 
CCACTGGCTC AGGTTGCTGC AGGTGGCACA CACAGTTTTG CTCTGTCTCT CACGGGGACA 
TCATTTGGCT GGGGGAGCAA CAGATCTGGG CAGTTGGCTC TCAGCGGGAA CAAAGTTAAA 
GAACAAATCT ACAAGCCGCA TTCAATTGGT GCCCTGAAGA ATCTGAGTGT GATTTATATT 
AGCTGTGGTT ATGAGCATAC TGCAGTGCTT ACTGAGGAGG GACAAGTGTT TACATTTGGA 
GGCAATAGCT CTGGACAACT ACAGCCCAGC CCCAGGAGTG GACAAAGAGG CCCACAACTC 
ATAGAAGGAA TTGGTGGCCG TGTTTCACAG ATAGAGTGCG CAAGTTATCA CACCATTGCA 
TATGTCTACA CCACTGGTCA GGTGGTATCT TTAGGCCGTG GACCAAGTCA CACAAGCAAC 
CCAACTCATC AGGAGGCCCC CGCAGAGAAC TCTGATATTA CCTGCCTGCT AGCTGCAGAG 
GACCTTGTGG ATATTGAAGT CAAAGACATT TTTGCTGGAG CACACGCCAA CTTTGTGACA 
ACTCGTCGGG TATCACATAC TAGGTCTACA GGTGTTTCCA TGAAAATCCT GCCAGAAATA 
ATCCGAATCA ACCAGTCTCT GGTAAAGAAA TGGAGAGCAG CAAATAAAAG AAAAGATCGT 
GAAGGCGCCA AAAGAGAAAT CAGCTTGATA TTTTCATCTT CTGCTTGTTT GACAGCGAGC 
TTTCTGAAGA AAAGAGATGC TGGAGAGAAT AATCTCATTG ATGTGGACTT AAAACTGGCA 
AGAGATGTCT TCAAGAAGTT AACAACAGAG AAATGGATTT CTTCTTTGAT AACCACGTGT 
CTTGAGGAGT ATCTGCTCAG AGATCTTCCA TACAGTTCTC CACACCAAGA AGCTCTACTT 
GTTTTTCTTT TGCTCCCAGA ATGTTCCATT ATGCAGGATC CTAAGAACTG GAAGACCCTG 
GCATTTGAAT TTGCAAAAGC TATTCATAAA ATGGGTCCAC AGTCATTAGC ATTCCTGAGA 
ACGTGTTGGG CATCTTTGGA AGTTTCTTCA CTGAACATAC TGGTTCAGAT GCTAAAGAAA 
GCCATCATCT CTCAAATACA GTATGGAGTT GCAACGGAGC AGTATATTAC TAATATTAAA 
GTTCTTTTAG AAGTGATAAA AGAAGTGCAT AAGGCTAACT GTCAACTTCC AGAAAGTGCC 
TTCATCATAA ATGAGCTTTC TGGCATCTTT AACTTTGATG CAGAGGCAGG AAGAATGTTC 
ATACGGCATA ACGATCTGGA CTGTACAGAA TCCTCAGATA TGGTTGTTTT CAGTGATTTT 
CTATTTGTCT TTGATTTGCC ATCCAAAATT AAACTAATGA AATGTGACTC ATTTGTAAAA 
CTGATGTCTG AAGTCATGGC ATTTCCAGAA AAGATGAGCT CCCCACCATA CCTTATACTG 
AAAGTCAGAC GAAGTCACCT GGTGGAAGAC ACATTGCGTC AATTAAGACA AGTGGAAGAC 
TTTGACCTTA GGAAGCAACT ATCGGTTGGA TTTATTAATG AAATTCGTCC TGAGGCTGGG 
GGAGTGAGTT CAGAGTTCTT CCACTGTATA TTTGAAGAGA TGACAGACCC CAAATATGAA 
ATGTTCATAT ATCCTGAAAA GGGTTCCAGC ATGTGGTTTC CAGTCAATCC CAAGTTTGAG 
AAGAGCAGCT ATTTCCTATT TGGGATCTTA TGTGGACTCT CCCTACATAA CTTAAAGGTT 
ATCAACCTTC CTTTCCCACT GGCTTTATAT AAAAAACTTT TGAACCAAAA GCCATCTTTG 
GAAGACTTAA AAGAACTTAG TCTTCCCTTG GGGAGGAATT TGCAAGAAGT TCTAAATTGT 
GAGGCTGGTG ATATTGAAGA ACTTCACATG TATTTTTCTA TATACTGGGA TCAAAAAGAT 
GTTGATTTAA TTCCAGATGG GATCTCTGTG CCTGTGAATG AAACCAACAA GAGAGACTAT 
GTGTCTAAGT ATGTTGATTA CATTTTTAAC ATCTCTATAA AGACGATTTA TGAAGAATTT 
CATAGAGGAT TTTACAAAGT GTGTAACTGG GATATAATTA GGCAATTCCA GCCCGAAGAA 
CTAATGACAG CAATAATTGG AAATGCTACT TGTGACTGGA AACAATTTGA AAATAATTCA 
AAGTATAAAG ATGGATATGA CAAATCACAC CCAACTATTC TGCTGTTTTG GAAGGCTTTC 
CATGACTTAA CTTTGGATGA AAAGAAAAAA TTCCTCTTGT TTCTTACAGG ATGTGATAGG 
CTGCATGTGA AAGGCCTACA GAATGAAGGA ATAGTATTCC GGTGTTCTGA AACCTTCAGT 
GAAGAAGATA ACCCAAGATC ATTGACATGT CACAGGATGC TAGACCTACC TAAGTATTCC 
TCAATGCGAA GGATGAAGGA AGCACTTCAG GTTGCAATCA ACAATAGCAC GGGATTTGTC 
TCACAGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080268.1
CDS	46..3057
Translation	MYFSWAAGSRKPRRLKAGTSGIELLQAASGEHHSLLLFSNHRVYSCGDNSWGQLGQRRDQSTERPEPIQALNDLHVDLVSCGKEHSVAVCHKGKVFAWGAGSEGQLGIGEFKEISFMPTKIKALAGIKIIQVSCGHYHSLALSEDGHVFSWGRNSEGQLGLGKNSRSQAIPQKVKSLEGIPLAQVAAGGTHSFALSLTGTSFGWGSNRSGQLALSGNKVKEQIYKPHSIGALKNLSVIYISCGYEHTAVLTEEGQVFTFGGNSSGQLQPSPRSGQRGPQLIEGIGGRVSQIECASYHTIAYVYTTGQVVSLGRGPSHTSNPTHQEAPAENSDITCLLAAEDLVDIEVKDIFAGAHANFVTTRRVSHTRSTGVSMKILPEIIRINQSLVKKWRAANKRKDREGAKREISLIFSSSACLTASFLKKRDAGENNLIDVDLKLARDVFKKLTTEKWISSLITTCLEEYLLRDLPYSSPHQEALLVFLLLPECSIMQDPKNWKTLAFEFAKAIHKMGPQSLAFLRTCWASLEVSSLNILVQMLKKAIISQIQYGVATEQYITNIKVLLEVIKEVHKANCQLPESAFIINELSGIFNFDAEAGRMFIRHNDLDCTESSDMVVFSDFLFVFDLPSKIKLMKCDSFVKLMSEVMAFPEKMSSPPYLILKVRRSHLVEDTLRQLRQVEDFDLRKQLSVGFINEIRPEAGGVSSEFFHCIFEEMTDPKYEMFIYPEKGSSMWFPVNPKFEKSSYFLFGILCGLSLHNLKVINLPFPLALYKKLLNQKPSLEDLKELSLPLGRNLQEVLNCEAGDIEELHMYFSIYWDQKDVDLIPDGISVPVNETNKRDYVSKYVDYIFNISIKTIYEEFHRGFYKVCNWDIIRQFQPEELMTAIIGNATCDWKQFENNSKYKDGYDKSHPTILLFWKAFHDLTLDEKKKFLLFLTGCDRLHVKGLQNEGIVFRCSETFSEEDNPRSLTCHRMLDLPKYSSMRRMKEALQVAINNSTGFVSQE

Target ORF information:

RefSeq Version	NM_025992.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus hect domain and RLD 6 (Herc6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025992.2

ORF Insert Sequence:

ATGTATTTCA GCTGGGCTGC AGGAAGCCGG AAGCCTCGGC GCCTGAAGGC GGGAACCAGC 
GGCATTGAAC TCTTGCAGGC AGCCAGCGGG GAACACCACT CGCTCCTACT GTTCAGCAAC 
CACAGGGTGT ATTCCTGCGG GGACAACAGC TGGGGACAGC TGGGCCAGAG GAGAGACCAG 
AGTACCGAAA GGCCAGAACC AATTCAGGCA CTGAATGATC TGCATGTTGA CCTGGTGAGC 
TGTGGGAAGG AACACTCTGT GGCTGTCTGC CACAAAGGAA AGGTCTTCGC TTGGGGAGCC 
GGTTCTGAAG GGCAGCTGGG GATTGGAGAA TTTAAGGAAA TAAGCTTTAT GCCTACGAAA 
ATAAAAGCTC TGGCTGGCAT AAAAATAATC CAAGTTTCCT GTGGACACTA CCACTCTTTG 
GCCTTATCAG AAGATGGCCA CGTGTTTTCA TGGGGAAGGA ACAGTGAAGG ACAACTGGGC 
CTGGGGAAGA ATTCCCGTTC TCAAGCTATT CCACAGAAGG TGAAGTCTCT GGAGGGGATC 
CCACTGGCTC AGGTTGCTGC AGGTGGCACA CACAGTTTTG CTCTGTCTCT CACGGGGACA 
TCATTTGGCT GGGGGAGCAA CAGATCTGGG CAGTTGGCTC TCAGCGGGAA CAAAGTTAAA 
GAACAAATCT ACAAGCCGCA TTCAATTGGT GCCCTGAAGA ATCTGAGTGT GATTTATATT 
AGCTGTGGTT ATGAGCATAC TGCAGTGCTT ACTGAGGAGG GACAAGTGTT TACATTTGGA 
GGCAATAGCT CTGGACAACT ACAGCCCAGC CCCAGGAGTG GACAAAGAGG CCCACAACTC 
ATAGAAGGAA TTGGTGGCCG TGTTTCACAG ATAGAGTGCG CAAGTTATCA CACCATTGCA 
TATGTCTACA CCACTGGTCA GGTGGTATCT TTAGGCCGTG GACCAAGTCA CACAAGCAAC 
CCAACTCATC AGGAGGCCCC CGCAGAGAAC TCTGATATTA CCTGCCTGCT AGCTGCAGAG 
GACCTTGTGG ATATTGAAGT CAAAGACATT TTTGCTGGAG CACACGCCAA CTTTGTGACA 
ACTCGTCGGG TATCACATAC TAGGTCTACA GGTGTTTCCA TGAAAATCCT GCCAGAAATA 
ATCCGAATCA ACCAGTCTCT GGTAAAGAAA TGGAGAGCAG CAAATAAAAG AAAAGATCGT 
GAAGGCGCCA AAAGAGAAAT CAGCTTGATA TTTTCATCTT CTGCTTGTTT GACAGCGAGC 
TTTCTGAAGA AAAGAGATGC TGGAGAGAAT AATCTCATTG ATGTGGACTT AAAACTGGCA 
AGAGATGTCT TCAAGAAGTT AACAACAGAG AAATGGATTT CTTCTTTGAT AACCACGTGT 
CTTGAGGAGT ATCTGCTCAG AGATCTTCCA TACAGTTCTC CACACCAAGA AGCTCTACTT 
GTTTTTCTTT TGCTCCCAGA ATGTTCCATT ATGCAGGATC CTAAGAACTG GAAGACCCTG 
GCATTTGAAT TTGCAAAAGC TATTCATAAA ATGGGTCCAC AGTCATTAGC ATTCCTGAGA 
ACGTGTTGGG CATCTTTGGA AGTTTCTTCA CTGAACATAC TGGTTCAGAT GCTAAAGAAA 
GCCATCATCT CTCAAATACA GTATGGAGTT GCAACGGAGC AGTATATTAC TAATATTAAA 
GTTCTTTTAG AAGTGATAAA AGAAGTGCAT AAGGCTAACT GTCAACTTCC AGAAAGTGCC 
TTCATCATAA ATGAGCTTTC TGGCATCTTT AACTTTGATG CAGAGGCAGG AAGAATGTTC 
ATACGGCATA ACGATCTGGA CTGTACAGAA TCCTCAGATA TGGTTGTTTT CAGTGATTTT 
CTATTTGTCT TTGATTTGCC ATCCAAAATT AAACTAATGA AATGTGACTC ATTTGTAAAA 
CTGATGTCTG AAGTCATGGC ATTTCCAGAA AAGATGAGCT CCCCACCATA CCTTATACTG 
AAAGTCAGAC GAAGTCACCT GGTGGAAGAC ACATTGCGTC AATTAAGACA AGTGGAAGAC 
TTTGACCTTA GGAAGCAACT ATCGGTTGGA TTTATTAATG AAATTCGTCC TGAGGCTGGG 
GGAGTGAGTT CAGAGTTCTT CCACTGTATA TTTGAAGAGA TGACAGACCC CAAATATGAA 
ATGTTCATAT ATCCTGAAAA GGGTTCCAGC ATGTGGTTTC CAGTCAATCC CAAGTTTGAG 
AAGAGCAGCT ATTTCCTATT TGGGATCTTA TGTGGACTCT CCCTACATAA CTTAAAGGTT 
ATCAACCTTC CTTTCCCACT GGCTTTATAT AAAAAACTTT TGAACCAAAA GCCATCTTTG 
GAAGACTTAA AAGAACTTAG TCTTCCCTTG GGGAGGAATT TGCAAGAAGT TCTAAATTGT 
GAGGCTGGTG ATATTGAAGA ACTTCACATG TATTTTTCTA TATACTGGGA TCAAAAAGAT 
GTTGATTTAA TTCCAGATGG GATCTCTGTG CCTGTGAATG AAACCAACAA GAGAGACTAT 
GTGTCTAAGT ATGTTGATTA CATTTTTAAC ATCTCTATAA AGACGATTTA TGAAGAATTT 
CATAGAGGAT TTTACAAAGT GTGTAACTGG GATATAATTA GGCAATTCCA GCCCGAAGAA 
CTAATGACAG CAATAATTGG AAATGCTACT TGTGACTGGA AACAATTTGA AAATAATTCA 
AAGTATAAAG ATGGATATGA CAAATCACAC CCAACTATTC TGCTGTTTTG GAAGGCTTTC 
CATGACTTAA CTTTGGATGA AAAGAAAAAA TTCCTCTTGT TTCTTACAGG ATGTGATAGG 
CTGCATGTGA AAGGCCTACA GAATGAAGGA ATAGTATTCC GGTGTTCTGA AACCTTCAGT 
GAAGAAGATA ACCCAAGATC ATTGACATGT CACAGGATGC TAGACCTACC TAAGTATTCC 
TCAATGCGAA GGATGAAGGA AGCACTTCAG GTTGCAATCA ACAATAGCAC GGGATTTGTC 
TCACAGGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research35(5)351-8(2015 May)
Arimoto K,Hishiki T,Kiyonari H,Abe T,Cheng C,Yan M,Fan JB,Futakuchi M,Tsuda H,Murakami Y,Suzuki H,Zhang DE,Shimotohno K

Mice without macroH2A histone variants.
Molecular and cellular biology34(24)4523-33(2014 Dec)
Pehrson JR,Changolkar LN,Costanzi C,Leu NA

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Cancer cell24(3)305-17(2013 Sep)
Nagamachi A,Matsui H,Asou H,Ozaki Y,Aki D,Kanai A,Takubo K,Suda T,Nakamura T,Wolff L,Honda H,Inaba T

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Herc6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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