Tpgs2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tpgs2
Entrez Gene ID	66648
Full Name	tubulin polyglutamylase complex subunit 2
Synonyms	5730437P09Rik,5730494M16Rik,AI666318,Pgs2
General protein information	Preferred Names tubulin polyglutamylase complex subunit 2 Names tubulin polyglutamylase complex subunit 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 A2

mRNA and Protein(s)

mRNA	Protein	Name
XM_006526156.3	XP_006526219.1	tubulin polyglutamylase complex subunit 2 isoform X1
XM_006526157.3	XP_006526220.1	tubulin polyglutamylase complex subunit 2 isoform X2
XM_006526156.4	XP_006526219.1	tubulin polyglutamylase complex subunit 2 isoform X1
NM_001142698.1	NP_001136170.1	tubulin polyglutamylase complex subunit 2 isoform c
NM_001142697.1	NP_001136169.1	tubulin polyglutamylase complex subunit 2 isoform b
NM_001004361.2	NP_001004361.2	tubulin polyglutamylase complex subunit 2 isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	TPGS2	NP_056291.2
Mus musculus (house mouse)	Tpgs2	NP_001004361.2
	C18orf10	XP_001107335.1
Rattus norvegicus (Norway rat)	Tpgs2	NP_001014169.2
Gallus gallus (chicken)	C18ORF10	XP_004937136.1
Xenopus tropicalis (tropical clawed frog)	tpgs2	NP_001016890.1
Bos taurus (cattle)	TPGS2	NP_001095714.1
Drosophila melanogaster (fruit fly)	CG6931	NP_648536.1
Pan troglodytes (chimpanzee)	TPGS2	XP_001140586.1
Canis lupus familiaris (dog)	TPGS2	XP_537279.4
Danio rerio (zebrafish)	tpgs2	NP_001002208.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010475	XP_311469.2

Gene Ontology
Bibliography

Related articles in PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.
Evsikov AV, Graber JH, Brockman JM, Hampl A, Holbrook AE, Singh P, Eppig JJ, Solter D, Knowles BB
Genes & development20(19)2713-27(2006 Oct)

Tubulin polyglutamylase enzymes are members of the TTL domain protein family.
Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Edd? B
Science (New York, N.Y.)308(5729)1758-62(2005 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tpgs2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tpgs2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06506	NM_001142697.1 Latest version!	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu06507	NM_001142698.1 Latest version!	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu10586	NM_001004361.2 Latest version!	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu54731	XM_006526157.3 Latest version!	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu54730	XM_006526156.4 Latest version!	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu54730	XM_006526156.3	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tpgs2 ( NM_001142697.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001136169.1 Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu06506
Clone ID Related Accession (Same CDS sequence)	NM_001142697.1
Accession Version	NM_001142697.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Mus musculus(house mouse)
Product	tubulin polyglutamylase complex subunit 2 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DV655125.1, AC124441.5 and AI666318.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation from a downstream start codon, compared to variant 1. The resulting isoform (b) is shorter at the N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DV655125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164141 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATTTCTT CATGGGAACA GAAAAACAAT TGTGTGATGC CTGAGGATGT GAGAAACTTC 
TACTTGATGA CCAATGGTTT TCACATGACC TGGAGTGTGA AGCTAGATGA GCACATTATT 
CCACTGGGAA GCATGGTGAT TAACGGCATT TCAAAACTGA CTCAGCTCAT CCAGTCTTCT 
GTGTACTCAC TTCCTAATGC ACCAACTCTG GCAGACCTAG AGGACGATAC TCAAGAAGGA 
AATGAAGACC ACCAGCTAGA GAAGCCTCAC TTTGACTGTC GCAGTGCAAT ATTTGAGCTG 
GATTCATGCA ATGGGAATGG GAAAGTTTGC CTCGTCTACA AAAATGGGAA ACCTGGGTTA 
GCTCATGACA CTGAGATATG GTTCCTGGAC AGAGCATTAT ACTGGCACTT TCTCACGGAT 
ACCTTTACCG CCTATTACCG CCTGCTCATC ACCCACCTGG GCCTGCCCCA GTGGCAGTAT 
GCCTTTACCA GCTATGGCAT TAGCCCACAG GCCAAGCAAT GGTTCAGTAT GTACAAACCC 
ATCACCTACA ACACAAGCCT GCTCACAGAA GAGTCCGACA ACTTTGTGAA CAAGCTAGAC 
CCCAGCAAAG TGTTCAAGAG CAAGAACAAG ATTTTAATCC CAAAAAAGAA AGGGCCTGTA 
CCACCTGCCA GTGGTCAGAA AGGGCCTGGG CCCTTACCTC CTCCTACCTC TAAGCCTACC 
ACAGGCTCTG GAAATCCTGT CCGAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136169.1
CDS	157..906
Translation	MISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFVNKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK

Target ORF information:

RefSeq Version	NM_001142697.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142697.1

ORF Insert Sequence:

ATGATTTCTT CATGGGAACA GAAAAACAAT TGTGTGATGC CTGAGGATGT GAGAAACTTC 
TACTTGATGA CCAATGGTTT TCACATGACC TGGAGTGTGA AGCTAGATGA GCACATTATT 
CCACTGGGAA GCATGGTGAT TAACGGCATT TCAAAACTGA CTCAGCTCAT CCAGTCTTCT 
GTGTACTCAC TTCCTAATGC ACCAACTCTG GCAGACCTAG AGGACGATAC TCAAGAAGGA 
AATGAAGACC ACCAGCTAGA GAAGCCTCAC TTTGACTGTC GCAGTGCAAT ATTTGAGCTG 
GATTCATGCA ATGGGAATGG GAAAGTTTGC CTCGTCTACA AAAATGGGAA ACCTGGGTTA 
GCTCATGACA CTGAGATATG GTTCCTGGAC AGAGCATTAT ACTGGCACTT TCTCACGGAT 
ACCTTTACCG CCTATTACCG CCTGCTCATC ACCCACCTGG GCCTGCCCCA GTGGCAGTAT 
GCCTTTACCA GCTATGGCAT TAGCCCACAG GCCAAGCAAT GGTTCAGTAT GTACAAACCC 
ATCACCTACA ACACAAGCCT GCTCACAGAA GAGTCCGACA ACTTTGTGAA CAAGCTAGAC 
CCCAGCAAAG TGTTCAAGAG CAAGAACAAG ATTTTAATCC CAAAAAAGAA AGGGCCTGTA 
CCACCTGCCA GTGGTCAGAA AGGGCCTGGG CCCTTACCTC CTCCTACCTC TAAGCCTACC 
ACAGGCTCTG GAAATCCTGT CCGAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tpgs2 ( NM_001142698.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001136170.1 Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu06507
Clone ID Related Accession (Same CDS sequence)	NM_001142698.1
Accession Version	NM_001142698.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Mus musculus(house mouse)
Product	tubulin polyglutamylase complex subunit 2 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ770487.1, BC060253.1, AK141632.1 and AC124441.5. Transcript Variant: This variant (3) differs in the 3' UTR and 3' coding region, compared to variant 1. The resulting isoform (c) is shorter and has a distinct C-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGAGGAGA CAACGCCCCC ACTGCAAGCC GGCAGCAAGC CGCACCTTGA GAAGTTGACC 
CTAGGCGTCA CTCGCATCCT GGAATCTTCC CCAGGTGTGA CCGAGGTGAG CATAATAGAA 
AAGCTGCCTG CTGAGCGTCA TATGATTTCT TCATGGGAAC AGAAAAACAA TTGTGTGATG 
CCTGAGGATG TGAGAAACTT CTACTTGATG ACCAATGGTT TTCACATGAC CTGGAGTGTG 
AAGCTAGATG AGCACATTAT TCCACTGGGA AGCATGGTGA TTAACGGCAT TTCAAAACTG 
ACTCAGCTCA TCCAGTCTTC TGTGTACTCA CTTCCTAATG CACCAACTCT GGCAGACCTA 
GAGGACGATA CTCAAGAAGG AAATGAAGAC CACCAGCTAG AGAAGCCTCA CTTTGACTGT 
CGCAGTGCAA TATTTGAGCT GGATTCATGC AATGGGAATG GGAAAGTTTG CCTCGTCTAC 
AAAAATGGGA AACCTGGGTT AGCTCATGAC ACTGAGATAT GGTTCCTGGA CAGAGCATTA 
TACTGGCACT TTCTCACGGA TACCTTTACC GCCTATTACC GCCTGCTCAT CACCCACCTG 
GGCCTGCCCC AGTGGCAGTA TGCCTTTACC AGCTATGGCA TTAGCCCACA GGCCAAGGTA 
GCTTCTATCT ATAGTCAAGA AGAAAGCATG AATTTCCAAG CAACATCTGT TAGAAACCAA 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136170.1
CDS	270..995
Translation	MEETTPPLQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHMISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKVASIYSQEESMNFQATSVRNQW

Target ORF information:

RefSeq Version	NM_001142698.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142698.1

ORF Insert Sequence:

ATGGAGGAGA CAACGCCCCC ACTGCAAGCC GGCAGCAAGC CGCACCTTGA GAAGTTGACC 
CTAGGCGTCA CTCGCATCCT GGAATCTTCC CCAGGTGTGA CCGAGGTGAG CATAATAGAA 
AAGCTGCCTG CTGAGCGTCA TATGATTTCT TCATGGGAAC AGAAAAACAA TTGTGTGATG 
CCTGAGGATG TGAGAAACTT CTACTTGATG ACCAATGGTT TTCACATGAC CTGGAGTGTG 
AAGCTAGATG AGCACATTAT TCCACTGGGA AGCATGGTGA TTAACGGCAT TTCAAAACTG 
ACTCAGCTCA TCCAGTCTTC TGTGTACTCA CTTCCTAATG CACCAACTCT GGCAGACCTA 
GAGGACGATA CTCAAGAAGG AAATGAAGAC CACCAGCTAG AGAAGCCTCA CTTTGACTGT 
CGCAGTGCAA TATTTGAGCT GGATTCATGC AATGGGAATG GGAAAGTTTG CCTCGTCTAC 
AAAAATGGGA AACCTGGGTT AGCTCATGAC ACTGAGATAT GGTTCCTGGA CAGAGCATTA 
TACTGGCACT TTCTCACGGA TACCTTTACC GCCTATTACC GCCTGCTCAT CACCCACCTG 
GGCCTGCCCC AGTGGCAGTA TGCCTTTACC AGCTATGGCA TTAGCCCACA GGCCAAGGTA 
GCTTCTATCT ATAGTCAAGA AGAAAGCATG AATTTCCAAG CAACATCTGT TAGAAACCAA 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tpgs2 ( NM_001004361.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001004361.2 Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10586
Clone ID Related Accession (Same CDS sequence)	NM_001004361.2
Accession Version	NM_001004361.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Mus musculus(house mouse)
Product	tubulin polyglutamylase complex subunit 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ770487.1, BC060253.1, AK017728.1, AC124441.5 and AI666318.1. On Dec 17, 2008 this sequence version replaced NM_001004361.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.200620.1, SRR1660821.181057.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164141 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGA CAACGCCCCC ACTGCAAGCC GGCAGCAAGC CGCACCTTGA GAAGTTGACC 
CTAGGCGTCA CTCGCATCCT GGAATCTTCC CCAGGTGTGA CCGAGGTGAG CATAATAGAA 
AAGCTGCCTG CTGAGCGTCA TATGATTTCT TCATGGGAAC AGAAAAACAA TTGTGTGATG 
CCTGAGGATG TGAGAAACTT CTACTTGATG ACCAATGGTT TTCACATGAC CTGGAGTGTG 
AAGCTAGATG AGCACATTAT TCCACTGGGA AGCATGGTGA TTAACGGCAT TTCAAAACTG 
ACTCAGCTCA TCCAGTCTTC TGTGTACTCA CTTCCTAATG CACCAACTCT GGCAGACCTA 
GAGGACGATA CTCAAGAAGG AAATGAAGAC CACCAGCTAG AGAAGCCTCA CTTTGACTGT 
CGCAGTGCAA TATTTGAGCT GGATTCATGC AATGGGAATG GGAAAGTTTG CCTCGTCTAC 
AAAAATGGGA AACCTGGGTT AGCTCATGAC ACTGAGATAT GGTTCCTGGA CAGAGCATTA 
TACTGGCACT TTCTCACGGA TACCTTTACC GCCTATTACC GCCTGCTCAT CACCCACCTG 
GGCCTGCCCC AGTGGCAGTA TGCCTTTACC AGCTATGGCA TTAGCCCACA GGCCAAGCAA 
TGGTTCAGTA TGTACAAACC CATCACCTAC AACACAAGCC TGCTCACAGA AGAGTCCGAC 
AACTTTGTGA ACAAGCTAGA CCCCAGCAAA GTGTTCAAGA GCAAGAACAA GATTTTAATC 
CCAAAAAAGA AAGGGCCTGT ACCACCTGCC AGTGGTCAGA AAGGGCCTGG GCCCTTACCT 
CCTCCTACCT CTAAGCCTAC CACAGGCTCT GGAAATCCTG TCCGAAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004361.2
CDS	270..1160
Translation	MEETTPPLQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHMISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFVNKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK

Target ORF information:

RefSeq Version	NM_001004361.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004361.2

ORF Insert Sequence:

ATGGAGGAGA CAACGCCCCC ACTGCAAGCC GGCAGCAAGC CGCACCTTGA GAAGTTGACC 
CTAGGCGTCA CTCGCATCCT GGAATCTTCC CCAGGTGTGA CCGAGGTGAG CATAATAGAA 
AAGCTGCCTG CTGAGCGTCA TATGATTTCT TCATGGGAAC AGAAAAACAA TTGTGTGATG 
CCTGAGGATG TGAGAAACTT CTACTTGATG ACCAATGGTT TTCACATGAC CTGGAGTGTG 
AAGCTAGATG AGCACATTAT TCCACTGGGA AGCATGGTGA TTAACGGCAT TTCAAAACTG 
ACTCAGCTCA TCCAGTCTTC TGTGTACTCA CTTCCTAATG CACCAACTCT GGCAGACCTA 
GAGGACGATA CTCAAGAAGG AAATGAAGAC CACCAGCTAG AGAAGCCTCA CTTTGACTGT 
CGCAGTGCAA TATTTGAGCT GGATTCATGC AATGGGAATG GGAAAGTTTG CCTCGTCTAC 
AAAAATGGGA AACCTGGGTT AGCTCATGAC ACTGAGATAT GGTTCCTGGA CAGAGCATTA 
TACTGGCACT TTCTCACGGA TACCTTTACC GCCTATTACC GCCTGCTCAT CACCCACCTG 
GGCCTGCCCC AGTGGCAGTA TGCCTTTACC AGCTATGGCA TTAGCCCACA GGCCAAGCAA 
TGGTTCAGTA TGTACAAACC CATCACCTAC AACACAAGCC TGCTCACAGA AGAGTCCGAC 
AACTTTGTGA ACAAGCTAGA CCCCAGCAAA GTGTTCAAGA GCAAGAACAA GATTTTAATC 
CCAAAAAAGA AAGGGCCTGT ACCACCTGCC AGTGGTCAGA AAGGGCCTGG GCCCTTACCT 
CCTCCTACCT CTAAGCCTAC CACAGGCTCT GGAAATCCTG TCCGAAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tpgs2 ( XM_006526156.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526219.1 Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54730
Clone ID Related Accession (Same CDS sequence)	XM_006526156.3 , XM_006526156.4
Accession Version	XM_006526156.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	tubulin polyglutamylase complex subunit 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526156.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTCTT CTGGAAATGA AGACCACCAG CTAGAGAAGC CTCACTTTGA CTGTCGCAGT 
GCAATATTTG AGCTGGATTC ATGCAATGGG AATGGGAAAG TTTGCCTCGT CTACAAAAAT 
GGGAAACCTG GGTTAGCTCA TGACACTGAG ATATGGTTCC TGGACAGAGC ATTATACTGG 
CACTTTCTCA CGGATACCTT TACCGCCTAT TACCGCCTGC TCATCACCCA CCTGGGCCTG 
CCCCAGTGGC AGTATGCCTT TACCAGCTAT GGCATTAGCC CACAGGCCAA GCAATGGTTC 
AGTATGTACA AACCCATCAC CTACAACACA AGCCTGCTCA CAGAAGAGTC CGACAACTTT 
GTGAACAAGC TAGACCCCAG CAAAGTGTTC AAGAGCAAGA ACAAGATTTT AATCCCAAAA 
AAGAAAGGGC CTGTACCACC TGCCAGTGGT CAGAAAGGGC CTGGGCCCTT ACCTCCTCCT 
ACCTCTAAGC CTACCACAGG CTCTGGAAAT CCTGTCCGAA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526219.1
CDS	29..553
Translation	MPSSGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFVNKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK

Target ORF information:

RefSeq Version	XM_006526156.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526156.3

ORF Insert Sequence:

ATGCCCTCTT CTGGAAATGA AGACCACCAG CTAGAGAAGC CTCACTTTGA CTGTCGCAGT 
GCAATATTTG AGCTGGATTC ATGCAATGGG AATGGGAAAG TTTGCCTCGT CTACAAAAAT 
GGGAAACCTG GGTTAGCTCA TGACACTGAG ATATGGTTCC TGGACAGAGC ATTATACTGG 
CACTTTCTCA CGGATACCTT TACCGCCTAT TACCGCCTGC TCATCACCCA CCTGGGCCTG 
CCCCAGTGGC AGTATGCCTT TACCAGCTAT GGCATTAGCC CACAGGCCAA GCAATGGTTC 
AGTATGTACA AACCCATCAC CTACAACACA AGCCTGCTCA CAGAAGAGTC CGACAACTTT 
GTGAACAAGC TAGACCCCAG CAAAGTGTTC AAGAGCAAGA ACAAGATTTT AATCCCAAAA 
AAGAAAGGGC CTGTACCACC TGCCAGTGGT CAGAAAGGGC CTGGGCCCTT ACCTCCTCCT 
ACCTCTAAGC CTACCACAGG CTCTGGAAAT CCTGTCCGAA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tpgs2 ( XM_006526157.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526220.1 Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu54731
Clone ID Related Accession (Same CDS sequence)	XM_006526157.3
Accession Version	XM_006526157.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	tubulin polyglutamylase complex subunit 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526157.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGA CAACGCCCCC ACTGCAAGCC GGCAGCAAGC CGCACCTTGA GAAGTTGACC 
CTAGGCGTCA CTCGCATCCT GGAATCTTCC CCAGGTGTGA CCGAGGTGAG CATAATAGAA 
AAGCTGCCTG CTGAGCGTCA TATGATTTCT TCATGGGAAC AGAAAAACAA TTGTGTGATG 
CCTGAGGATG TGAGAAACTT CTACTTGATG ACCAATGGTT TTCACATGAC CTGGAGTGTG 
AAGCTAGATG AGCACATTAT TCCACTGGGA AGCATGGTGA TTAACGGCAT TTCAAAACTG 
ACTCAGCTCA TCCAGTCTTC TGTGTACTCA CTTCCTAATG CACCAACTCT GGCAGACCTA 
GAGGACGATA CTCAAGAAGG AAGTCAGATA GAAGCAGAAG AGAAAACAAA AGAAAATTTC 
ATGAAGGAAA TTCCAGGGTC ATGTCTGTAT CCCATTTTTA ATTGTACTAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526220.1
CDS	401..874
Translation	MEETTPPLQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHMISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGSQIEAEEKTKENFMKEIPGSCLYPIFNCTI

Target ORF information:

RefSeq Version	XM_006526157.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526157.3

ORF Insert Sequence:

ATGGAGGAGA CAACGCCCCC ACTGCAAGCC GGCAGCAAGC CGCACCTTGA GAAGTTGACC 
CTAGGCGTCA CTCGCATCCT GGAATCTTCC CCAGGTGTGA CCGAGGTGAG CATAATAGAA 
AAGCTGCCTG CTGAGCGTCA TATGATTTCT TCATGGGAAC AGAAAAACAA TTGTGTGATG 
CCTGAGGATG TGAGAAACTT CTACTTGATG ACCAATGGTT TTCACATGAC CTGGAGTGTG 
AAGCTAGATG AGCACATTAT TCCACTGGGA AGCATGGTGA TTAACGGCAT TTCAAAACTG 
ACTCAGCTCA TCCAGTCTTC TGTGTACTCA CTTCCTAATG CACCAACTCT GGCAGACCTA 
GAGGACGATA CTCAAGAAGG AAGTCAGATA GAAGCAGAAG AGAAAACAAA AGAAAATTTC 
ATGAAGGAAA TTCCAGGGTC ATGTCTGTAT CCCATTTTTA ATTGTACTAT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tpgs2 ( XM_006526156.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526219.1 Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu54730
Clone ID Related Accession (Same CDS sequence)	XM_006526156.3 , XM_006526156.4
Accession Version	XM_006526156.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	tubulin polyglutamylase complex subunit 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006526156.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTCTT CTGGAAATGA AGACCACCAG CTAGAGAAGC CTCACTTTGA CTGTCGCAGT 
GCAATATTTG AGCTGGATTC ATGCAATGGG AATGGGAAAG TTTGCCTCGT CTACAAAAAT 
GGGAAACCTG GGTTAGCTCA TGACACTGAG ATATGGTTCC TGGACAGAGC ATTATACTGG 
CACTTTCTCA CGGATACCTT TACCGCCTAT TACCGCCTGC TCATCACCCA CCTGGGCCTG 
CCCCAGTGGC AGTATGCCTT TACCAGCTAT GGCATTAGCC CACAGGCCAA GCAATGGTTC 
AGTATGTACA AACCCATCAC CTACAACACA AGCCTGCTCA CAGAAGAGTC CGACAACTTT 
GTGAACAAGC TAGACCCCAG CAAAGTGTTC AAGAGCAAGA ACAAGATTTT AATCCCAAAA 
AAGAAAGGGC CTGTACCACC TGCCAGTGGT CAGAAAGGGC CTGGGCCCTT ACCTCCTCCT 
ACCTCTAAGC CTACCACAGG CTCTGGAAAT CCTGTCCGAA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526219.1
CDS	190..714
Translation	MPSSGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFVNKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK

Target ORF information:

RefSeq Version	XM_006526156.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus tubulin polyglutamylase complex subunit 2 (Tpgs2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526156.4

ORF Insert Sequence:

ATGCCCTCTT CTGGAAATGA AGACCACCAG CTAGAGAAGC CTCACTTTGA CTGTCGCAGT 
GCAATATTTG AGCTGGATTC ATGCAATGGG AATGGGAAAG TTTGCCTCGT CTACAAAAAT 
GGGAAACCTG GGTTAGCTCA TGACACTGAG ATATGGTTCC TGGACAGAGC ATTATACTGG 
CACTTTCTCA CGGATACCTT TACCGCCTAT TACCGCCTGC TCATCACCCA CCTGGGCCTG 
CCCCAGTGGC AGTATGCCTT TACCAGCTAT GGCATTAGCC CACAGGCCAA GCAATGGTTC 
AGTATGTACA AACCCATCAC CTACAACACA AGCCTGCTCA CAGAAGAGTC CGACAACTTT 
GTGAACAAGC TAGACCCCAG CAAAGTGTTC AAGAGCAAGA ACAAGATTTT AATCCCAAAA 
AAGAAAGGGC CTGTACCACC TGCCAGTGGT CAGAAAGGGC CTGGGCCCTT ACCTCCTCCT 
ACCTCTAAGC CTACCACAGG CTCTGGAAAT CCTGTCCGAA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.
Genes & development20(19)2713-27(2006 Oct)
Evsikov AV,Graber JH,Brockman JM,Hampl A,Holbrook AE,Singh P,Eppig JJ,Solter D,Knowles BB

Tubulin polyglutamylase enzymes are members of the TTL domain protein family.
Science (New York, N.Y.)308(5729)1758-62(2005 Jun)
Janke C,Rogowski K,Wloga D,Regnard C,Kajava AV,Strub JM,Temurak N,van Dijk J,Boucher D,van Dorsselaer A,Suryavanshi S,Gaertig J,Edd? B

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Tpgs2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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