Exosc3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Exosc3
Entrez Gene ID	66362
Full Name	exosome component 3
Synonyms	2310005D06Rik,AI593501,Rrp40
General protein information	Preferred Names exosome component 3 Names exosome complex component RRP40 exosome complex exonuclease RRP40 ribosomal RNA-processing protein 40
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001362788.1	NP_001349717.1	exosome complex component RRP40 isoform 2
NM_025513.3	NP_079789.1	exosome complex component RRP40
NM_025513.4	NP_079789.1	exosome complex component RRP40 isoform 1

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	exos-3	NP_492751.1
Eremothecium gossypii	AGOS_ADL196W	NP_983900.2
Schizosaccharomyces pombe (fission yeast)	SPAC22A12.12c	NP_593242.1
Bos taurus (cattle)	EXOSC3	NP_001030474.1
Rattus norvegicus (Norway rat)	Exosc3	NP_001101406.1
Saccharomyces cerevisiae (baker's yeast)	RRP40	NP_014499.2
Neurospora crassa	NCU00693	XP_965833.1
Canis lupus familiaris (dog)	EXOSC3	XP_538738.1
Mus musculus (house mouse)	Exosc3	NP_079789.1
Gallus gallus (chicken)	EXOSC3	NP_001186445.1
Danio rerio (zebrafish)	exosc3	NP_001025132.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010247	XP_319438.3
Kluyveromyces lactis	KLLA0E02091g	XP_454042.1
	EXOSC3	XP_001114719.1
Arabidopsis thaliana (thale cress)	AT4G32175	NP_680755.2
Arabidopsis thaliana (thale cress)	AT2G25355	NP_565592.1
Oryza sativa (rice)	Os01g0661400	NP_001043778.1
Homo sapiens (human)	EXOSC3	NP_057126.2
Pan troglodytes (chimpanzee)	EXOSC3	XP_520587.2
Drosophila melanogaster (fruit fly)	Rrp40	NP_722725.1
Magnaporthe oryzae (rice blast fungus)	MGG_02843	XP_003720894.1
Xenopus tropicalis (tropical clawed frog)	LOC100491278	XP_002936379.2

Gene Ontology
Bibliography

Related articles in PubMed

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.
Rialdi A, Hultquist J, Jimenez-Morales D, Peralta Z, Campisi L, Fenouil R, Moshkina N, Wang ZZ, Laffleur B, Kaake RM, McGregor MJ, Haas K, Pefanis E, Albrecht RA, Pache L, Chanda S, Jen J, Ochando J, Byun M, Basu U, Garc?a-Sastre A, Krogan N, van Bakel H, Marazzi I
Cell169(4)679-692.e14(2017 May)

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.
Lim J, Giri PK, Kazadi D, Laffleur B, Zhang W, Grinstein V, Pefanis E, Brown LM, Ladewig E, Martin O, Chen Y, Rabadan R, Boyer F, Rothschild G, Cogn? M, Pinaud E, Deng H, Basu U
Cell169(3)523-537.e15(2017 Apr)

Widespread and dynamic translational control of red blood cell development.
Alvarez-Dominguez JR, Zhang X, Hu W
Blood129(5)619-629(2017 02)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity.
Pefanis E, Wang J, Rothschild G, Lim J, Kazadi D, Sun J, Federation A, Chao J, Elliott O, Liu ZP, Economides AN, Bradner JE, Rabadan R, Basu U
Cell161(4)774-89(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EXOSC3 mutations account for 30%-40% of patients with PCH1 with variability in survival and clinical severity that is correlated with the genotype.
Title: Pontocerebellar hypoplasia type 1: clinical spectrum and relevance of EXOSC3 mutations.

The following Exosc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exosc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13448	NM_025513.4 Latest version!	Mus musculus exosome component 3 (Exosc3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu84359	NM_001362788.1 Latest version!	Mus musculus exosome component 3 (Exosc3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu13448	NM_025513.3	Mus musculus exosome component 3 (Exosc3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Exosc3 ( NM_025513.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079789.1 Mus musculus exosome component 3 (Exosc3), mRNA.

Price & Availability↑

CloneID	OMu13448
Clone ID Related Accession (Same CDS sequence)	NM_025513.3 , NM_025513.4
Accession Version	NM_025513.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Mus musculus(house mouse)
Product	exosome complex component RRP40
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL772285.9. On May 1, 2007 this sequence version replaced NM_025513.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC054085.1, BC023669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGAAG TACTGTCCGC GGGACCGGAG TCGGTGGCGG GCTGCCGAGC ACGGGCCGTG 
CACAAGGTGC TGAATCAGGT GGTTCTCCCC GGGGAGGAGC TGGTGCTGCC GGACCACGAG 
GACGTAGACG GCCTTGGCGG CGCCGGGGAG CAGCCGTTAC GCCTGAATGC GGGTGCGCGC 
CCGAGGCTGC GCGTAGTGTG TGGCCCAGGT TTGCGACGCT GCGGGGACCG TCTGCTGGTC 
ACCAAGTGTG GCCGCCTGCG TCACAAGGAG CCCAGCGGAG GCGGCGGCGG CGTTTACTGG 
GTGGACTCGC AGCAGAAGCG GTATGTACCT GTGAAAGGGG ACCACGTGAT TGGCATAGTG 
ATCGCTAAAT CTGGAGATAT ATTCAAAGTT GATGTTGGAG GGAGTGAGCC AGCGTCTTTG 
TCTTACCTGG CATTTGAAGG GGCAACTAAA AGAAACAGAC CAAATGTGCA GGTTGGAGAT 
CTCATCTATG GCCAGTGTGT GGTCGCTAAT AAAGACATGG AACCAGAGAT GGTCTGCATT 
GACAGCTGTG GCCGCGCCAA TGGGATGGGT GTGATTGGGC AGGATGGCCT GCTCTTCAAA 
GTGACGTTGG GCTTAATTAG AAAGCTATTA GCTCCAGATT GTGAAATTGT GCAAGAGCTG 
GGAAAACTCT ATCCATTGGA GATTGTGTTT GGAATGAATG GAAGAATATG GGTCAAAGCT 
AAGACCATTC AGCAGACGTT AATTTTAGCA AATGTCTTAG AAGCTTGTGA ACACATGACA 
ACAGAGCAAA GAAAACAGAT CTTTGCCAGA CTGGCAGAGA GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079789.1
CDS	13..837
Translation	MAEVLSAGPESVAGCRARAVHKVLNQVVLPGEELVLPDHEDVDGLGGAGEQPLRLNAGARPRLRVVCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARLAES

Target ORF information:

RefSeq Version	NM_025513.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus exosome component 3 (Exosc3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025513.3

ORF Insert Sequence:

ATGGCTGAAG TACTGTCCGC GGGACCGGAG TCGGTGGCGG GCTGCCGAGC ACGGGCCGTG 
CACAAGGTGC TGAATCAGGT GGTTCTCCCC GGGGAGGAGC TGGTGCTGCC GGACCACGAG 
GACGTAGACG GCCTTGGCGG CGCCGGGGAG CAGCCGTTAC GCCTGAATGC GGGTGCGCGC 
CCGAGGCTGC GCGTAGTGTG TGGCCCAGGT TTGCGACGCT GCGGGGACCG TCTGCTGGTC 
ACCAAGTGTG GCCGCCTGCG TCACAAGGAG CCCAGCGGAG GCGGCGGCGG CGTTTACTGG 
GTGGACTCGC AGCAGAAGCG GTATGTACCT GTGAAAGGGG ACCACGTGAT TGGCATAGTG 
ATCGCTAAAT CTGGAGATAT ATTCAAAGTT GATGTTGGAG GGAGTGAGCC AGCGTCTTTG 
TCTTACCTGG CATTTGAAGG GGCAACTAAA AGAAACAGAC CAAATGTGCA GGTTGGAGAT 
CTCATCTATG GCCAGTGTGT GGTCGCTAAT AAAGACATGG AACCAGAGAT GGTCTGCATT 
GACAGCTGTG GCCGCGCCAA TGGGATGGGT GTGATTGGGC AGGATGGCCT GCTCTTCAAA 
GTGACGTTGG GCTTAATTAG AAAGCTATTA GCTCCAGATT GTGAAATTGT GCAAGAGCTG 
GGAAAACTCT ATCCATTGGA GATTGTGTTT GGAATGAATG GAAGAATATG GGTCAAAGCT 
AAGACCATTC AGCAGACGTT AATTTTAGCA AATGTCTTAG AAGCTTGTGA ACACATGACA 
ACAGAGCAAA GAAAACAGAT CTTTGCCAGA CTGGCAGAGA GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Exosc3 ( NM_025513.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079789.1 Mus musculus exosome component 3 (Exosc3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu13448
Clone ID Related Accession (Same CDS sequence)	NM_025513.3 , NM_025513.4
Accession Version	NM_025513.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	exosome complex component RRP40 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL772285.9. On Apr 27, 2018 this sequence version replaced NM_025513.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC023669.1, BC054085.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TACTGTCCGC GGGACCGGAG TCGGTGGCGG GCTGCCGAGC ACGGGCCGTG 
CACAAGGTGC TGAATCAGGT GGTTCTCCCC GGGGAGGAGC TGGTGCTGCC GGACCACGAG 
GACGTAGACG GCCTTGGCGG CGCCGGGGAG CAGCCGTTAC GCCTGAATGC GGGTGCGCGC 
CCGAGGCTGC GCGTAGTGTG TGGCCCAGGT TTGCGACGCT GCGGGGACCG TCTGCTGGTC 
ACCAAGTGTG GCCGCCTGCG TCACAAGGAG CCCAGCGGAG GCGGCGGCGG CGTTTACTGG 
GTGGACTCGC AGCAGAAGCG GTATGTACCT GTGAAAGGGG ACCACGTGAT TGGCATAGTG 
ATCGCTAAAT CTGGAGATAT ATTCAAAGTT GATGTTGGAG GGAGTGAGCC AGCGTCTTTG 
TCTTACCTGG CATTTGAAGG GGCAACTAAA AGAAACAGAC CAAATGTGCA GGTTGGAGAT 
CTCATCTATG GCCAGTGTGT GGTCGCTAAT AAAGACATGG AACCAGAGAT GGTCTGCATT 
GACAGCTGTG GCCGCGCCAA TGGGATGGGT GTGATTGGGC AGGATGGCCT GCTCTTCAAA 
GTGACGTTGG GCTTAATTAG AAAGCTATTA GCTCCAGATT GTGAAATTGT GCAAGAGCTG 
GGAAAACTCT ATCCATTGGA GATTGTGTTT GGAATGAATG GAAGAATATG GGTCAAAGCT 
AAGACCATTC AGCAGACGTT AATTTTAGCA AATGTCTTAG AAGCTTGTGA ACACATGACA 
ACAGAGCAAA GAAAACAGAT CTTTGCCAGA CTGGCAGAGA GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079789.1
CDS	26..850
Translation	MAEVLSAGPESVAGCRARAVHKVLNQVVLPGEELVLPDHEDVDGLGGAGEQPLRLNAGARPRLRVVCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARLAES

Target ORF information:

RefSeq Version	NM_025513.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus exosome component 3 (Exosc3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025513.4

ORF Insert Sequence:

ATGGCTGAAG TACTGTCCGC GGGACCGGAG TCGGTGGCGG GCTGCCGAGC ACGGGCCGTG 
CACAAGGTGC TGAATCAGGT GGTTCTCCCC GGGGAGGAGC TGGTGCTGCC GGACCACGAG 
GACGTAGACG GCCTTGGCGG CGCCGGGGAG CAGCCGTTAC GCCTGAATGC GGGTGCGCGC 
CCGAGGCTGC GCGTAGTGTG TGGCCCAGGT TTGCGACGCT GCGGGGACCG TCTGCTGGTC 
ACCAAGTGTG GCCGCCTGCG TCACAAGGAG CCCAGCGGAG GCGGCGGCGG CGTTTACTGG 
GTGGACTCGC AGCAGAAGCG GTATGTACCT GTGAAAGGGG ACCACGTGAT TGGCATAGTG 
ATCGCTAAAT CTGGAGATAT ATTCAAAGTT GATGTTGGAG GGAGTGAGCC AGCGTCTTTG 
TCTTACCTGG CATTTGAAGG GGCAACTAAA AGAAACAGAC CAAATGTGCA GGTTGGAGAT 
CTCATCTATG GCCAGTGTGT GGTCGCTAAT AAAGACATGG AACCAGAGAT GGTCTGCATT 
GACAGCTGTG GCCGCGCCAA TGGGATGGGT GTGATTGGGC AGGATGGCCT GCTCTTCAAA 
GTGACGTTGG GCTTAATTAG AAAGCTATTA GCTCCAGATT GTGAAATTGT GCAAGAGCTG 
GGAAAACTCT ATCCATTGGA GATTGTGTTT GGAATGAATG GAAGAATATG GGTCAAAGCT 
AAGACCATTC AGCAGACGTT AATTTTAGCA AATGTCTTAG AAGCTTGTGA ACACATGACA 
ACAGAGCAAA GAAAACAGAT CTTTGCCAGA CTGGCAGAGA GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Exosc3 ( NM_001362788.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001349717.1 Mus musculus exosome component 3 (Exosc3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu84359
Clone ID Related Accession (Same CDS sequence)	NM_001362788.1
Accession Version	NM_001362788.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	exosome complex component RRP40 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL772285.9. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AV504859.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TACTGTCCGC GGGACCGGAG TCGGTGGCGG GCTGCCGAGC ACGGGCCGTG 
CACAAGTATG TACCTGTGAA AGGGGACCAC GTGATTGGCA TAGTGATCGC TAAATCTGGA 
GATATATTCA AAGTTGATGT TGGAGGGAGT GAGCCAGCGT CTTTGTCTTA CCTGGCATTT 
GAAGGGGCAA CTAAAAGAAA CAGACCAAAT GTGCAGGTTG GAGATCTCAT CTATGGCCAG 
TGTGTGGTCG CTAATAAAGA CATGGAACCA GAGATGGTCT GCATTGACAG CTGTGGCCGC 
GCCAATGGGA TGGGTGTGAT TGGGCAGGAT GGCCTGCTCT TCAAAGTGAC GTTGGGCTTA 
ATTAGAAAGC TATTAGCTCC AGATTGTGAA ATTGTGCAAG AGCTGGGAAA ACTCTATCCA 
TTGGAGATTG TGTTTGGAAT GAATGGAAGA ATATGGGTCA AAGCTAAGAC CATTCAGCAG 
ACGTTAATTT TAGCAAATGT CTTAGAAGCT TGTGAACACA TGACAACAGA GCAAAGAAAA 
CAGATCTTTG CCAGACTGGC AGAGAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001349717.1
CDS	26..595
Translation	MAEVLSAGPESVAGCRARAVHKYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARLAES

Target ORF information:

RefSeq Version	NM_001362788.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus exosome component 3 (Exosc3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001362788.1

ORF Insert Sequence:

ATGGCTGAAG TACTGTCCGC GGGACCGGAG TCGGTGGCGG GCTGCCGAGC ACGGGCCGTG 
CACAAGTATG TACCTGTGAA AGGGGACCAC GTGATTGGCA TAGTGATCGC TAAATCTGGA 
GATATATTCA AAGTTGATGT TGGAGGGAGT GAGCCAGCGT CTTTGTCTTA CCTGGCATTT 
GAAGGGGCAA CTAAAAGAAA CAGACCAAAT GTGCAGGTTG GAGATCTCAT CTATGGCCAG 
TGTGTGGTCG CTAATAAAGA CATGGAACCA GAGATGGTCT GCATTGACAG CTGTGGCCGC 
GCCAATGGGA TGGGTGTGAT TGGGCAGGAT GGCCTGCTCT TCAAAGTGAC GTTGGGCTTA 
ATTAGAAAGC TATTAGCTCC AGATTGTGAA ATTGTGCAAG AGCTGGGAAA ACTCTATCCA 
TTGGAGATTG TGTTTGGAAT GAATGGAAGA ATATGGGTCA AAGCTAAGAC CATTCAGCAG 
ACGTTAATTT TAGCAAATGT CTTAGAAGCT TGTGAACACA TGACAACAGA GCAAAGAAAA 
CAGATCTTTG CCAGACTGGC AGAGAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.
Cell169(4)679-692.e14(2017 May)
Rialdi A,Hultquist J,Jimenez-Morales D,Peralta Z,Campisi L,Fenouil R,Moshkina N,Wang ZZ,Laffleur B,Kaake RM,McGregor MJ,Haas K,Pefanis E,Albrecht RA,Pache L,Chanda S,Jen J,Ochando J,Byun M,Basu U,Garc?a-Sastre A,Krogan N,van Bakel H,Marazzi I

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.
Cell169(3)523-537.e15(2017 Apr)
Lim J,Giri PK,Kazadi D,Laffleur B,Zhang W,Grinstein V,Pefanis E,Brown LM,Ladewig E,Martin O,Chen Y,Rabadan R,Boyer F,Rothschild G,Cogn? M,Pinaud E,Deng H,Basu U

Widespread and dynamic translational control of red blood cell development.
Blood129(5)619-629(2017 02)
Alvarez-Dominguez JR,Zhang X,Hu W

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity.
Cell161(4)774-89(2015 May)
Pefanis E,Wang J,Rothschild G,Lim J,Kazadi D,Sun J,Federation A,Chao J,Elliott O,Liu ZP,Economides AN,Bradner JE,Rabadan R,Basu U

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Exosc3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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