Msmo1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Msmo1
Entrez Gene ID	66234
Full Name	methylsterol monoxygenase 1
Synonyms	1500001G16Rik,C78600,DESP4,ERG25,Sc4mol
General protein information	Preferred Names methylsterol monoxygenase 1 Names methylsterol monooxygenase 1 C-4 methylsterol oxidase sterol-C4-methyl oxidase-like
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 B3.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_025436.3	NP_079712.1	methylsterol monooxygenase 1
NM_025436.2	NP_079712.1	methylsterol monooxygenase 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MSMO1	XP_003310610.1
Gallus gallus (chicken)	MSMO1	NP_001006438.1
Danio rerio (zebrafish)	msmo1	NP_998518.1
Homo sapiens (human)	MSMO1	NP_006736.1
Rattus norvegicus (Norway rat)	Msmo1	NP_543162.1
	SC4MOL	XP_001101517.1
Bos taurus (cattle)	MSMO1	NP_001092333.1
Mus musculus (house mouse)	Sc4mol	NP_079712.1
Magnaporthe oryzae (rice blast fungus)	MGG_17103	XP_003716576.1
Xenopus tropicalis (tropical clawed frog)	msmo1	NP_001072809.1

Gene Ontology
Bibliography

Related articles in PubMed

Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.
Lowther KM, Favero F, Yang CR, Taylor HS, Seli E
Biology of reproduction96(2)341-351(2017 02)

A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
?i?ecio?lu M, Budak H, Geffers L, ?ankaya M, ?iftci M, Thaller C, Eichele G, K?frevio?lu ??, ?zdemir H
Journal of lipid research56(8)1551-9(2015 Aug)

Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.
Patra D, DeLassus E, Liang G, Sandell LJ
PloS one9(8)e105674(2014)

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This work identifies a critical role for SC4MOL and NSDHL in the regulation of EGFR signaling and endocytic trafficking and suggests novel strategies to increase the potency of EGFR antagonists in tumors
Title: Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.

The following Msmo1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Msmo1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19069	NM_025436.3 Latest version!	Mus musculus methylsterol monoxygenase 1 (Msmo1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu19069	NM_025436.2	Mus musculus methylsterol monoxygenase 1 (Msmo1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Msmo1 ( NM_025436.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079712.1 Mus musculus methylsterol monoxygenase 1 (Msmo1), mRNA.

Price & Availability↑

CloneID	OMu19069
Clone ID Related Accession (Same CDS sequence)	NM_025436.3 , NM_025436.2
Accession Version	NM_025436.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	methylsterol monooxygenase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK005090.1 and AC152168.2. On Jun 14, 2018 this sequence version replaced NM_025436.2. ##Evidence-Data-START## Transcript exon combination :: AK005090.1, AK151135.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCACAA ACAAAAGTGT TGGCGTGTTC AGCTCTGCAT CCCTGGCTGT GGAGTATGTG 
GACTCACTGT TGCCGGAGAA TCCTCTGCAG GAGCCCTTTA AGAATGCTTG GGTCTACATG 
TTGGACAACT ATACAAAGTT CCAGATCGCA ACCTGGGGCT CCCTGATAGT TCACGAAGCC 
ATCTATTTCT TGTTCTCTTT ACCTGGATTC CTATTCCAGT TTATACCTTA CATGAGAAAG 
TACAAGATTC AAAAGGATAA ACCAGAAACC TTCGAAGGCC AGTGGAAGTG TTTGAAAAAA 
ATTCTATTTA ATCATTTTTT TATCCAGTTG CCTCTGATTT GTGGAACATA CTATTTTACA 
GAGTTTTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTACTT AACTTTGGCA 
AGGTGTTTGG GCTGTGCAGT CATTGAGGAC ACCTGGCATT ATTTCCTGCA CAGACTCCTT 
CACCACAAGA GAATTTATAA ATACATTCAT AAAGTCCATC ACGAGTTTCA GGCTCCATTT 
GGAATCGAAG CAGAATACGC ACATCCCTTG GAAACCCTGA TTCTTGGGAC AGGATTTTTC 
ATCGGAATTG TGCTTTTGTG TGATCACGTA ATTCTCCTGT GGGCATGGGT GACCATACGT 
TTGCTGGAAA CCATCGATGT GCACAGCGGT TATGATATTC CTCTCAACCC GCTGAACTTG 
GTTCCTTTTT ATACGGGCGC TCGGCACCAT GATTTCCACC ACATGAACTT CATTGGGAAT 
TATGCCTCCA CCTTCACGTG GTGGGATAAA CTCTTTGGGA CAGATGCCCA GTATCATGCC 
TACATTGAAA AATCGAAGAA GCTTGGGAAA AAGTCTGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079712.1
CDS	102..983
Translation	MATNKSVGVFSSASLAVEYVDSLLPENPLQEPFKNAWVYMLDNYTKFQIATWGSLIVHEAIYFLFSLPGFLFQFIPYMRKYKIQKDKPETFEGQWKCLKKILFNHFFIQLPLICGTYYFTEFFNIPYDWERMPRWYLTLARCLGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGIEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLVPFYTGARHHDFHHMNFIGNYASTFTWWDKLFGTDAQYHAYIEKSKKLGKKSD

Target ORF information:

RefSeq Version	NM_025436.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus methylsterol monoxygenase 1 (Msmo1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025436.3

ORF Insert Sequence:

ATGGCCACAA ACAAAAGTGT TGGCGTGTTC AGCTCTGCAT CCCTGGCTGT GGAGTATGTG 
GACTCACTGT TGCCGGAGAA TCCTCTGCAG GAGCCCTTTA AGAATGCTTG GGTCTACATG 
TTGGACAACT ATACAAAGTT CCAGATCGCA ACCTGGGGCT CCCTGATAGT TCACGAAGCC 
ATCTATTTCT TGTTCTCTTT ACCTGGATTC CTATTCCAGT TTATACCTTA CATGAGAAAG 
TACAAGATTC AAAAGGATAA ACCAGAAACC TTCGAAGGCC AGTGGAAGTG TTTGAAAAAA 
ATTCTATTTA ATCATTTTTT TATCCAGTTG CCTCTGATTT GTGGAACATA CTATTTTACA 
GAGTTTTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTACTT AACTTTGGCA 
AGGTGTTTGG GCTGTGCAGT CATTGAGGAC ACCTGGCATT ATTTCCTGCA CAGACTCCTT 
CACCACAAGA GAATTTATAA ATACATTCAT AAAGTCCATC ACGAGTTTCA GGCTCCATTT 
GGAATCGAAG CAGAATACGC ACATCCCTTG GAAACCCTGA TTCTTGGGAC AGGATTTTTC 
ATCGGAATTG TGCTTTTGTG TGATCACGTA ATTCTCCTGT GGGCATGGGT GACCATACGT 
TTGCTGGAAA CCATCGATGT GCACAGCGGT TATGATATTC CTCTCAACCC GCTGAACTTG 
GTTCCTTTTT ATACGGGCGC TCGGCACCAT GATTTCCACC ACATGAACTT CATTGGGAAT 
TATGCCTCCA CCTTCACGTG GTGGGATAAA CTCTTTGGGA CAGATGCCCA GTATCATGCC 
TACATTGAAA AATCGAAGAA GCTTGGGAAA AAGTCTGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msmo1 ( NM_025436.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079712.1 Mus musculus methylsterol monoxygenase 1 (Msmo1), mRNA.

Price & Availability↑

CloneID	OMu19069
Clone ID Related Accession (Same CDS sequence)	NM_025436.3 , NM_025436.2
Accession Version	NM_025436.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-09
Organism	Mus musculus(house mouse)
Product	methylsterol monooxygenase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK005090.1. On Apr 6, 2007 this sequence version replaced NM_025436.1. ##Evidence-Data-START## Transcript exon combination :: AK005090.1, AK151135.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGCCACAA ACAAAAGTGT TGGCGTGTTC AGCTCTGCAT CCCTGGCTGT GGAGTATGTG 
GACTCACTGT TGCCGGAGAA TCCTCTGCAG GAGCCCTTTA AGAATGCTTG GGTCTACATG 
TTGGACAACT ATACAAAGTT CCAGATCGCA ACCTGGGGCT CCCTGATAGT TCACGAAGCC 
ATCTATTTCT TGTTCTCTTT ACCTGGATTC CTATTCCAGT TTATACCTTA CATGAGAAAG 
TACAAGATTC AAAAGGATAA ACCAGAAACC TTCGAAGGCC AGTGGAAGTG TTTGAAAAAA 
ATTCTATTTA ATCATTTTTT TATCCAGTTG CCTCTGATTT GTGGAACATA CTATTTTACA 
GAGTTTTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTACTT AACTTTGGCA 
AGGTGTTTGG GCTGTGCAGT CATTGAGGAC ACCTGGCATT ATTTCCTGCA CAGACTCCTT 
CACCACAAGA GAATTTATAA ATACATTCAT AAAGTCCATC ACGAGTTTCA GGCTCCATTT 
GGAATCGAAG CAGAATACGC ACATCCCTTG GAAACCCTGA TTCTTGGGAC AGGATTTTTC 
ATCGGAATTG TGCTTTTGTG TGATCACGTA ATTCTCCTGT GGGCATGGGT GACCATACGT 
TTGCTGGAAA CCATCGATGT GCACAGCGGT TATGATATTC CTCTCAACCC GCTGAACTTG 
GTTCCTTTTT ATACGGGCGC TCGGCACCAT GATTTCCACC ACATGAACTT CATTGGGAAT 
TATGCCTCCA CCTTCACGTG GTGGGATAAA CTCTTTGGGA CAGATGCCCA GTATCATGCC 
TACATTGAAA AATCGAAGAA GCTTGGGAAA AAGTCTGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079712.1
CDS	102..983
Translation	MATNKSVGVFSSASLAVEYVDSLLPENPLQEPFKNAWVYMLDNYTKFQIATWGSLIVHEAIYFLFSLPGFLFQFIPYMRKYKIQKDKPETFEGQWKCLKKILFNHFFIQLPLICGTYYFTEFFNIPYDWERMPRWYLTLARCLGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGIEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLVPFYTGARHHDFHHMNFIGNYASTFTWWDKLFGTDAQYHAYIEKSKKLGKKSD

Target ORF information:

RefSeq Version	NM_025436.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus methylsterol monoxygenase 1 (Msmo1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025436.2

ORF Insert Sequence:

ATGGCCACAA ACAAAAGTGT TGGCGTGTTC AGCTCTGCAT CCCTGGCTGT GGAGTATGTG 
GACTCACTGT TGCCGGAGAA TCCTCTGCAG GAGCCCTTTA AGAATGCTTG GGTCTACATG 
TTGGACAACT ATACAAAGTT CCAGATCGCA ACCTGGGGCT CCCTGATAGT TCACGAAGCC 
ATCTATTTCT TGTTCTCTTT ACCTGGATTC CTATTCCAGT TTATACCTTA CATGAGAAAG 
TACAAGATTC AAAAGGATAA ACCAGAAACC TTCGAAGGCC AGTGGAAGTG TTTGAAAAAA 
ATTCTATTTA ATCATTTTTT TATCCAGTTG CCTCTGATTT GTGGAACATA CTATTTTACA 
GAGTTTTTCA ATATTCCTTA TGATTGGGAA AGAATGCCAA GATGGTACTT AACTTTGGCA 
AGGTGTTTGG GCTGTGCAGT CATTGAGGAC ACCTGGCATT ATTTCCTGCA CAGACTCCTT 
CACCACAAGA GAATTTATAA ATACATTCAT AAAGTCCATC ACGAGTTTCA GGCTCCATTT 
GGAATCGAAG CAGAATACGC ACATCCCTTG GAAACCCTGA TTCTTGGGAC AGGATTTTTC 
ATCGGAATTG TGCTTTTGTG TGATCACGTA ATTCTCCTGT GGGCATGGGT GACCATACGT 
TTGCTGGAAA CCATCGATGT GCACAGCGGT TATGATATTC CTCTCAACCC GCTGAACTTG 
GTTCCTTTTT ATACGGGCGC TCGGCACCAT GATTTCCACC ACATGAACTT CATTGGGAAT 
TATGCCTCCA CCTTCACGTG GTGGGATAAA CTCTTTGGGA CAGATGCCCA GTATCATGCC 
TACATTGAAA AATCGAAGAA GCTTGGGAAA AAGTCTGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.
Biology of reproduction96(2)341-351(2017 02)
Lowther KM,Favero F,Yang CR,Taylor HS,Seli E

A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
Journal of lipid research56(8)1551-9(2015 Aug)
?i?ecio?lu M,Budak H,Geffers L,?ankaya M,?iftci M,Thaller C,Eichele G,K?frevio?lu ??,?zdemir H

Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.
PloS one9(8)e105674(2014)
Patra D,DeLassus E,Liang G,Sandell LJ

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Miller JA,Nathanson J,Franjic D,Shim S,Dalley RA,Shapouri S,Smith KA,Sunkin SM,Bernard A,Bennett JL,Lee CK,Hawrylycz MJ,Jones AR,Amaral DG,?estan N,Gage FH,Lein ES

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Msmo1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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