Rgcc cDNA ORF clone, Mus musculus(house mouse)

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.
Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF
Proceedings of the National Academy of Sciences of the United States of America110(10)4081-6(2013 Mar)

results identify RGC-32 as a novel regulator of Th17 cell differentiation in vitro and in vivo and suggest that RGC-32 is a potential therapeutic target in multiple sclerosis and other Th17-mediated autoimmune diseases
Title: RGC-32 Promotes Th17 Cell Differentiation and Enhances Experimental Autoimmune Encephalomyelitis.

results demonstrate that RGC-32 contributes to the development of hepatic steatosis by facilitating de novo lipogenesis through activating liver X receptor, leading to the induction of SREBP-1c and its target genes
Title: RGC-32 Deficiency Protects against Hepatic Steatosis by Reducing Lipogenesis.

RGC-32 is involved in controlling the cell cycle of T cells in vivo, and this effect is mediated by IL-2 in a PI3K-dependent fashion.
Title: RGC-32 is a novel regulator of the T-lymphocyte cell cycle.

RGC32 plays an important role in diet-induced obesity and insulin resistance, and thus it may serve as a potential novel drug target for developing therapeutics to treat obesity and metabolic disorders.
Title: RGC32 deficiency protects against high-fat diet-induced obesity and insulin resistance in mice.

results demonstrate for the first time that RGC-32 is a novel membrane regulator for macrophage phagocytosis.
Title: Response gene to complement 32 protein promotes macrophage phagocytosis via activation of protein kinase C pathway.