Cts6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cts6
Entrez Gene ID	58518
Full Name	cathepsin 6
Synonyms	1600022N02Rik
General protein information	Preferred Names cathepsin 6 Names cathepsin 6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 B2\|13 32.67 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_021445.1	NP_067420.1	cathepsin 6 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ctsr	NP_783171.2
Mus musculus (house mouse)	Cts6	NP_067420.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Peg3 mutational effects on reproduction and placenta-specific gene families.
Kim J, Frey WD, He H, Kim H, Ekram MB, Bakshi A, Faisal M, Perera BP, Ye A, Teruyama R
PloS one8(12)e83359(2013)

Genomic evolution of the placenta using co-option and duplication and divergence.
Knox K, Baker JC
Genome research18(5)695-705(2008 May)

Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13.
Deussing J, Kouadio M, Rehman S, Werber I, Schwinde A, Peters C
Genomics79(2)225-40(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cts6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cts6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12351	NM_021445.1 Latest version!	Mus musculus cathepsin 6 (Cts6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cts6 ( NM_021445.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067420.1 Mus musculus cathepsin 6 (Cts6), mRNA.

Price & Availability↑

CloneID	OMu12351
Clone ID Related Accession (Same CDS sequence)	NM_021445.1
Accession Version	NM_021445.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Mus musculus(house mouse)
Product	cathepsin 6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF223401.1. ##Evidence-Data-START## Transcript exon combination :: AF223401.1, BC099455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGAGTCCTA CTTTATTTTT GGCCATCCTG TGTTTGGGAG TGGGCTCAGG TGCCCTAGCA 
CTTGATCCCA ATTTGAATGC TGAATGGCAT GATTGGAAGA AACAGTATGA AAAATCATAC 
ACCATGGAGG AAGAAGGACT GAGGAGAGCA ATATGGGAAG AAAACATGAG AATGATCAAA 
CTGCACAACT GGGAGAATAG CCTGGGGAAG AATAACTTCA CCTTGAAAAT GAATGAATTT 
GGTGACCTGA CTCCTGAAGA ACTCAGAAAA ATGATGAACA ATTTTCCAAT CTGGAGTCAC 
AAGAAGAGAA AAATCATCAG GAAGCGCGCA GTTGGTGATG TTCTACCCAA ATTTGTGGAC 
TGGAGAAAGA AAGGCTATGT GACTCGAGTA CGGAGACAGA AATTTTGTAA TTCCTGTTGG 
GCTTTTGCTG TGAATGGTGC CATAGAAGGA CAGATGTTCA AAAAAACTGG CAAACTCACC 
CCTCTGAGTG TTCAGAACCT AGTGGACTGT ACTAAAACTC AAGGAAATGA TGGCTGCCAA 
TGGGGTGATC CATACATTGC CTATGAATAT GTTTTGAATA ATGGAGGTCT GGAGGCTGAG 
GCAACCTATC CATATGAAGG AAAAGAAGGA CCATGCAGGT ACAATCCAAA GAATTCTAAG 
GCTGAAATCA CAGGATTTGT GTCCCTCCCA GAAAGCGAAG ATATTCTAAT GGAAGCTGTA 
GCAACTATTG GGCCCATCTC TGCTGCAGTG GATGCTTCCT TTAACAGATT CAGTTTCTAC 
GATGGAGGTA TTTATCATCA GCCAAATTGC AGCAATAATA CTGTGAATCA TGCAGTTCTG 
GTGGTTGGCT ATGGAACTGA GGGAAATGAA ACAGATGGCA ATAAGTACTG GCTAATCAAG 
AACAGCTGGG GTAGAAGATG GGGCATTGGA GGCTACATGA AGATTATCAG AGACCAGAAC 
AACCACTGTG GCATTGCTAC ATATGCACAT TATCCCATTG TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067420.1
CDS	65..1069
Translation	MSPTLFLAILCLGVGSGALALDPNLNAEWHDWKKQYEKSYTMEEEGLRRAIWEENMRMIKLHNWENSLGKNNFTLKMNEFGDLTPEELRKMMNNFPIWSHKKRKIIRKRAVGDVLPKFVDWRKKGYVTRVRRQKFCNSCWAFAVNGAIEGQMFKKTGKLTPLSVQNLVDCTKTQGNDGCQWGDPYIAYEYVLNNGGLEAEATYPYEGKEGPCRYNPKNSKAEITGFVSLPESEDILMEAVATIGPISAAVDASFNRFSFYDGGIYHQPNCSNNTVNHAVLVVGYGTEGNETDGNKYWLIKNSWGRRWGIGGYMKIIRDQNNHCGIATYAHYPIV

Target ORF information:

RefSeq Version	NM_021445.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cathepsin 6 (Cts6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021445.1

ORF Insert Sequence:

ATGAGTCCTA CTTTATTTTT GGCCATCCTG TGTTTGGGAG TGGGCTCAGG TGCCCTAGCA 
CTTGATCCCA ATTTGAATGC TGAATGGCAT GATTGGAAGA AACAGTATGA AAAATCATAC 
ACCATGGAGG AAGAAGGACT GAGGAGAGCA ATATGGGAAG AAAACATGAG AATGATCAAA 
CTGCACAACT GGGAGAATAG CCTGGGGAAG AATAACTTCA CCTTGAAAAT GAATGAATTT 
GGTGACCTGA CTCCTGAAGA ACTCAGAAAA ATGATGAACA ATTTTCCAAT CTGGAGTCAC 
AAGAAGAGAA AAATCATCAG GAAGCGCGCA GTTGGTGATG TTCTACCCAA ATTTGTGGAC 
TGGAGAAAGA AAGGCTATGT GACTCGAGTA CGGAGACAGA AATTTTGTAA TTCCTGTTGG 
GCTTTTGCTG TGAATGGTGC CATAGAAGGA CAGATGTTCA AAAAAACTGG CAAACTCACC 
CCTCTGAGTG TTCAGAACCT AGTGGACTGT ACTAAAACTC AAGGAAATGA TGGCTGCCAA 
TGGGGTGATC CATACATTGC CTATGAATAT GTTTTGAATA ATGGAGGTCT GGAGGCTGAG 
GCAACCTATC CATATGAAGG AAAAGAAGGA CCATGCAGGT ACAATCCAAA GAATTCTAAG 
GCTGAAATCA CAGGATTTGT GTCCCTCCCA GAAAGCGAAG ATATTCTAAT GGAAGCTGTA 
GCAACTATTG GGCCCATCTC TGCTGCAGTG GATGCTTCCT TTAACAGATT CAGTTTCTAC 
GATGGAGGTA TTTATCATCA GCCAAATTGC AGCAATAATA CTGTGAATCA TGCAGTTCTG 
GTGGTTGGCT ATGGAACTGA GGGAAATGAA ACAGATGGCA ATAAGTACTG GCTAATCAAG 
AACAGCTGGG GTAGAAGATG GGGCATTGGA GGCTACATGA AGATTATCAG AGACCAGAAC 
AACCACTGTG GCATTGCTAC ATATGCACAT TATCCCATTG TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Peg3 mutational effects on reproduction and placenta-specific gene families.
PloS one8(12)e83359(2013)
Kim J,Frey WD,He H,Kim H,Ekram MB,Bakshi A,Faisal M,Perera BP,Ye A,Teruyama R

Genomic evolution of the placenta using co-option and duplication and divergence.
Genome research18(5)695-705(2008 May)
Knox K,Baker JC

Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13.
Genomics79(2)225-40(2002 Feb)
Deussing J,Kouadio M,Rehman S,Werber I,Schwinde A,Peters C

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Cts6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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